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© 1994 Nature Publishing Group http://www.nature.com/nsmb

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© 1994 Nature Publishing Group http://www.nature.com/nsmb

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© 1994 Nature Publishing Group http://www.nature.com/nsmb

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© 1994 Nature Publishing Group http://www.nature.com/nsmb

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© 1994 Nature Publishing Group http://www.nature.com/nsmb

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