high value products
8th Edition of the Les Rendez-vous de Concarneau• September, 29th and 30th 2016
" Where Industry meets Science"
high value products from microalgae … with
economic relevance
Vítor Verdelho VieiraPresident - European Algae Biomass AssociationMember for the Board - A4F Algae for Future
What is ‘ high value ’ ?
What is ‘economic relevance’ ?
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What is the microalgae…
…value framework ?
1. Value depends on Composition
Polysacharides(starch, glucose,
sugars)
Essentialaminoacids pattern
similar to food
Pigments(chlorophyll,
carotenoids andastaxanthin )
Microalgae
Proteins Carbohydrates
50% 20-30%
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Essential vitamins (A, B1, B2, B6, B12, C, E, nicotinate, biotin, folic acid and pantothenic
acid)
PUFAs (ARA, EPA, DHA)
astaxanthin )
Microalgae
Lipids Othercompounds
20-30% < 5%
2. Value depends on Applications
• Food ingredients
• Healthfoods
Food
• Premix feeds
• Specialty feeds
Feed
• Nutraceuticals
• Pharmaceuticals
Health
• Cosmeceuticals
• Thalassotherapy
Cosmetics
Current applications
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• Biofuels
• CO2 mitigation
Fuels
• Biofertilizer
• Soil microalgae
Fertilizers
• N&P removal
• Bioremediation
Wastewater
• Biofibers
• Chemical industry
Chemicals
Emerging applications
3. Value depends on Purity Level
Increasingly Market driven
Current product demand
Aquaculture
Paste
Food & Feed
Aquaculture
Dried
Ceuticals
Extracts
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demand
New Products
BiorefineryConcept
Ceuticals
The products from microalgae have currently only three possible forms
4. Value depends on Formulation
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Only 3 possibilities:
PASTE DRIED EXTRACTS
Mostly for: Aquaculture Food & Feed Ceuticals
usually from 5 to 15% Dry Weight with different packaging
spray-dried,freeze-dried or just sun-dried
solvents, super-critically extracts or just with
mechanical processes
Value-chain analysis is a complex topic very often mentionedby non-experts that bring a highly confusing, misleading andunclear approach.
The 'value-chain' is defined in a business context as:" the interrelated operating activities businesses
5. Value depends on ‘value-chain’ Position
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" the interrelated operating activities businessesperform during the process of converting rawmaterials into finished products" .
The concept comes from business management and was first described and popularized by Michael Porterin his 1985 best-seller (Competitive Advantage: Creating and Sustaining Superior Performance).
Business value chain Product value chain
> Value-chain for microalgae biomass
PRODUCTION PROCESSING DISTRIBUTION
PRIMARY
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SUPPORT
PRODUCTS
APPLICATIONS
> Value-chain for microalgae based products
FORMULATION DISTRIBUTION
PRIMARY
The global microalgae value chainfor any microalgae or microalgaebased product can be quite simple
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SUPPORT
PRODUCTS
APPLICATIONS
based product can be quite simpleor complex. Different steps wherevalue is added along the processof transforming a biologicalmaterial in a product for a client oreven a consumer.
Different products can come-outin different points of the value-chain and they can be tradedforward to the next point of thechain or further to other point.
Packaging defines a product thatcan be traded.
Value chain and market values - examples
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Values for 2012 under updating
6. Value depends also on production Scale
SMALL SCALESMALL SCALE MEDIUM SCALEMEDIUM SCALE
< 5 haproduction: 10-100 ton /year
more than 500production facilities all over the world
5-50 haproduction: 100-500 ton/year
less than 300 production facilities mostly in China and other Asian countries
LARGE SCALELARGE SCALE
50-100 haproduction: 1000-5000 ton/y
less than 20 Spirulina production facilities with this scale
VERY LARGE SCALEVERY LARGE SCALE
> 100 ha > 5.000 ton /year
still no production facility with this sizeO
PE
N S
YS
TE
M
SU
RFA
CE
11/43LARGE SCALE DEPENDS ON HOW WE COMPARE WITH REFERENC ES
countries
CLO
SE
D S
YS
TE
M < 10 m3 -
production: < 1 ton/year
more than 100production facilities all over the world
SMALL SCALESMALL SCALE MEDIUM SCALEMEDIUM SCALE LARGE SCALELARGE SCALE VERY LARGE SCALEVERY LARGE SCALE
10-500 m3 production: 1-50 ton/year
less than 50production facilities all over the world
500-2.000 m3 production: 25-150 ton/year –
less than 10only 4 with more than 1.000 m3 (BGG, Algatech, Buggypower, Allmicroalgae)
> 2.000 m3
> 50-70 ton /year
still no production facility with this size
VO
LUM
E
there is also a very small scale > the microfarming with less than 0.5 ha
7. Value depends also on comparative reference
Soy: oil & meal Fish: oil & meal Algae: oil & meal
> 200 million ton/year of
production
> 7 million ton/year of
production
> 20 thousand ton/year of
production
Feed applications are the
most relevant
Feed applications are the
most relevant
Food applications are the
most relevant
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most relevant most relevant most relevant
Soy based feeds improved
with fish meal
Fish meal feeds are improved
with algae
Algae emerge as pre-mix feed
ingredient
Current value < 0.5 €
typically 0.35 €/Kg
Current value < 2 €
typically 1.5 €/Kg
Current value < 10 €
typically 10-20 €/kg
10 €/Kg is a high value
… when compared with 0.35€/Kg related oil products
Value chain and market values
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Values for 2012 – under updating
Value chain and market values
Values for 2012 – under updating
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Values for 2012 – under updating
Value chain and market values
Values for 2012 – under updating
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Value chain and market values
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Values for 2012 – under updating
Value chain and market values
Values for 2012 – under updating
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Values for 2012 – under updating
Value chain and market values
Values for 2012 – under updating
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Values for 2012 – under updating
Same examples
Aquaculture hatchery feeds
Aquarium feeds Premix feeds for farm animal
Specialty feeds for racing animal
Food ingredients for pet foods
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Agriculture extracts
Food ingredients Food supplements Nutraceuticals and health food
Cosmetics and cosmeceutical
Aquaculture hatchery feeds
www.tomalgae.comNannochloropsisoculata is the main cultured organism contained in PhytoBloom .
Nannochloropsis .
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www.phytobloom.com
www.brineshrimpdirect.com
http://reedmariculture.com/application_finfish.php
Nannochloropsis . Isochrysis
$47,25$75,00
AQUARIUM FEEDS
www.coralculture.co.uk/www.phytobloom.com
www.algaenergy.es/
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$29.99
www.petworldshop.com
www.phytobloom.com
www.dobbies.com/
www.bassleer.com
Chlorella
Spirulina
Farm animals premix feeds
Spirulina platensis, Haematococcus pluvialis, Chlorella sp, Chlorella protothecoides, Nannochloropsis sp, Chlorella sorokiniana,
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www.algaeinstitute.comwww.dhagold.com
DHA omega-3
www.tractorsupply.com/content_landing-page_dumor
www.actsinc.biz/algavit.html
Pet foods
www.watershed.net
Chlorella
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www.sunchlorellausa.com
www.livelypets.com
www.watershed.net
DHA omega-3
Racing animal speciality feeds
www.nouvelleresearch.com
Spirulina
DHA omega-3
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www.springtimeinc.com/product/longevity/All-Natural-Dog-Supplements
www.myshopping.com.au
www.dhagold.com
ww.algosud.com
Food ingredients
SPIRULINA
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http://elkenenstek.blogspot.pt/2013/10/elken-everyday.html
www.leebiscuits.com/pro03_filled_crackers.html
www.alibaba.com/product-detail/Spirulina-Filled-Crackers_160267840.htmlhttp://elkenenstek.blogspot.pt/2013/10/elken-everyday.html
http://m.shopclues.com/enerva-spirulina-cookies-2.html
Food ingredients
CHLORELLA AND SPIRULINA INGREDIENTS
€ 20,95
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www.emmaandtom.com www.jugojuice.com
http://www.bluebio.cn/
www.organo.dxneurope.eu/products
www.nl.nutress.eu
€42,40
http://www.mattisson.nl/shop/superfoods/absolute_supersmoothie_slimming_mix_bio_raw/47
Food ingredients
CHLORELLA AND SPIRULINA INGREDIENTS
www.algaeindustrymagazine.com Spirulina honey
€ 2,89
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www.spirulina.sg/Spirulina_Green_Tea.html
Spirulina contains 10-20% phycocyanin making it the best natural blue color for foods.
www.spirulina.sg/Spirulina_Honey.html
Food ingredients
SPIRULINA COLOR INGREDIENT
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Net weight: 500 g.Origin: Spain
3,15€www.spirulina.sg/Spirulina_Beer.html
www.microlife.bio
48,00€
Food supplements
SPIRULINA + CHLORELLA + DUNALIELLA
150g Powder - $82.95 / 71.51€
60 Count Bottle - $39.95 / 34.44€
$49,95 / 37,80€.
www.dr-peterhartig.de/power-22 www.e21usa.com
www.agmfoods.com
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49,99€150g Powder - $82.95 / 71.51€ $49,95 / 37,80€.
Powder: $49,95 / 37,80€Caps (each 596 mg): $61,55 / 46,60
29.99 / 25.85€360 capsules: $ 44,95 / 31,18€267g: $34,95 / 24,23€
240g: $25,95 / 17,99€
www.nowfoods.com
www.nourishinghub.com.au
www.greensplus.com
Food supplements
498.56€
DUNALIELLA
$26,42 / 18,64€
www.nikken-miho.com/index_ecat.php?cPath=2www.ethicalnutrients.com.au
www.earthalchemi.com.au/product/algotene-red-marine-phytoplankton-60-cap/
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303.98 €
$20,01 / 15,11€
60 caps: $28,90 / 21,84€; 180 caps: $69,30 / 52,37€
$26,42 / 18,64€
www.thompsonsnutrition.com.au
Food supplements
SPIRULINA
$ 22.55
£21.59/ 907g
33/43$45,30 / 31,96€
CHLORELLA + DUNALIELLA
5 oz (142g): 12 - $39,95 / 28,20€2.5 oz (354g): 30 - $68,95 / 48,68
www.sunchlorella.com
www.hollandandbarrett.com/pages/product_detail.asp?pid=822&MCatID=5&prodid=882&cid=47
ASTAXANTHIN
www.astasupreme.co.nz
Price range: $49.90 -$59.90
Nutraceuticals and health food
product with 30% = 300 US$ =>
1000 US$/ Kg 100% equivalent
PHYCOCYANINwww.euglena.jp/en/
www.earthrise.com
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50% BETAGLUCAN = 25-35 US$/Kg
1000 US$/ Kg 100% equivalent
15 € the 100 g pack
SPIRULINA
www.algalscientific.com
www.algaenergy.es
Nutraceuticals and health food
www.dsm.com
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Cosmetics and cosmeceuticals
Cellular Swiss Ice Crystal Advanced Marine Biology Repairwear Uplifting Firming Creamwww.laprairieswitzerland.com www.clinique.com
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www.ahava.com
€24.95 - 250 ml
Spirulina
17,95 €
www.naturespirit.de
£7.69
www.aubreyorganicsuk.co.uk
Blue Green Algae
www.algaenergy.es
Chlorella vulgarisIsochrysis galbana (T-ISO)
Cosmetics and cosmeceuticals
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www.mibellebiochemistry.com
Cosmetics and cosmeceuticals
It was not until 2010 that the Salins group began to study the microorganisms on the Salins. The expert scientific team in valuation of microalgae will examine the case of Dunaliella salina , a species of salt-tolerant green algae (iewho copes well with high salt concentration environments)
www.salins.com www.spiruline-des-iles-dor.com
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www.eclae.com
Price range: 14€ - 65€
Agriculture growth promoters and fertilizers
SPIRULINA
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www.algaenergy.es/
www.biorizon.es/Bioalgal_Marine/Algafert_Abonos_es.html
A4F – ALGAE FOR FUTURE
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A4F – ALGAE FOR FUTURE September 2016
A4F AlgaFuel SA was
established in 2008 and is
dedicated to Design, Build,
Operate and Transfer
(DBOT) of large-scale
microalgae plants.
A4F has a very close relationship with the leading scientists and researchers in the field of
microalgae biotechnologies, as well as with the largest microalgae producers, worldwide.
Therefore, A4F is a first choice for any large-scale contract as the best
specialist company in almost every specific aspects of microalgae
production with the most extended knowledge network.
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As a global company, A4F collaborate
in R&D European projects and offer
our consultancy services in Europe
(Portugal, Spain, France, UK, the
Netherlands, Germany), in the Middle
East (Saudi Arabia), South America,
and wherever our clients are.
While being a company involved in many activities within microalgae cultivation,
both in R&D and in implementation of industrial production units, A4F also helps
the clients in the development of the final products, including the biorefinery
concept.
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Program Acronym Topic Start date Duration
GIAVAPGenetic modification of marine or freshwater
algae to better suit industrial applications2010Nov 36 months
BIOFAT Biofuels from microalgae 2011Apr 48 months
ALGAPLEX Mixotrophic microalgae growth 2009Oct 24 months
DEMA Direct bioethanol from microalgae 2012Dez 54 months
R&D PROJECTS
PHOTO.COMMPhotosynthetic communities in industrial
cultivation2012Oct 48 months
ProEcoWine Plant protection products from microalgae 2012Nov 24 months
D-Factory Cultivation and biorefinery for Dunaliella 2013Dec 48 months
PUFAChainDeveloping a pipeline of PUFA-derived products
from several species of microalgae2013Nov 48 months
ALFF The Algal Microbiome Friends and Foes 2014Dec 48 months
PHOTOFUELStimulating the innovation potential of SMEs for
a low carbon energy system. 2015Jul 48 months
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LISBON EXPERIMENTAL UNIT: SERVICES
• Production conditions optimization of freshwater and marine microalgae
• Chlorella, Haematococcus, Nannochloropsis, Dunaliella, Phaeodactylum,
Spirulina, Synechocystis, Thalasiossira, Chlamydomonas ….
• GMO and non-GMO
• Water and nutritive medium management/optimization
• Culture medium treatment and recycling optimization
• Cultivation systems custom engineering
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• Cultivation systems custom engineering
• Biomass harvesting and processing
• Training in PBR, GW and CRW operation
Inputs + Management ���� Production ���� Outputs
S01
Water treatment
and distribution
S11
Offices S04
Laboratory S08
Harvesting
S02
Nutritive media
distribution
S12
Data acquisition and
control
S05
Inoculum S09
Processing
S03
Carbon delivery S06
Production PBR
S10
Effluents and
water recycling
S07
Thermoregulation
Wastewater management
LISBON EXPERIMENTAL UNIT: SYSTEMS & LAYOUT
45
S06. PBR
S12
Utilies
Unit implantation layout and systems description.
S01S03 S10
S08&
S09
S07
S11
Water recycling
LISBON EXPERIMENTAL UNIT: GMO
• Greenhouse to confine the PBR production area;
• GH and processing area ground was made impervious;
• Wastewater piping from GH and processing areas is collected in gutters connected
to a closed system into a 10 m3 decontamination tank with an exterior pipe
container allowing detection of leakages;
• Closed system communication between GH and processing area.
46Unit implantation layout and systems description.
LISBON
INNOVATION INNOVATION
LABORATORY
LIL
47
Mission
• A4F’s LIL is fully equipped to support R&D
activities. It houses A4F’s microalgae culture
collection, culture collection bank (backups
and inocula improvement programs for
production units) and hosts R&D experimental
projects and analysis in supporting pilot scale
and industrial production units.
Research activities
LISBON INNOVATION LABORATORY
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Research activities
• Cultivation and Scale-up (GMO certification)
• Analytical Biochemistry
• Molecular Biology
• Bright field and Fluorescence Microscopy
LISBON INNOVATION LABORATORY
Culture collection
• A4F´s Culture Collection includes close to 100 strains
of microalgae and cyanobacteria on site and privileged
access to more than 1200 isolates through
partnerships and contracts.
• Microalgae are isolated from sites of interest or
acquired for clients, R&D projects, biotechnology
development.development.
49
SERVICES PROVIDED BY A4F
50
Consultancy services
• Business case study for microalgae production
• Assessment of sites for microalgae production plants
• Design of microalgae production plants
• Technology procurement and selection – infrastructure, production equipment,
SERVICES PROVIDED BY A4F
51
• Technology procurement and selection – infrastructure, production equipment,
downstream processing and utilities for microalgae production plants
• Start-up, diagnosis and optimization of microalgae production plants
• Production supervision, team training and technology transfer at Clients’
microalgae production plants
• Funding opportunities for microalgae projects
• Support in sales, development and licensing of novel microalgal products
Technology supply
• Photobioreactors – mainly tubular and flat-panel, other options possible
according to suitability for different projects
• Open ponds - cascade and conventional raceways, other options possible
according to suitability for different projects
Fermentation reactors for microalgae production – his is in partnership with a
SERVICES PROVIDED BY A4F
52
• Fermentation reactors for microalgae production – his is in partnership with a
specialist company in yeast and bacteria fermentors.
• Implementation of complete microalgae production plants: from cell to tons
• Development of a complete product application platform: from tons to market
• Integration of microalgae production with existing industrial facilities (cement,
power, effluent treatment, fertilizer, etc.)
SERVICES PROVIDED BY A4F
Technical services
• Microalgae strain isolation, selection and characterization
• Inoculum production
• Specialized analytical services: pigments, fatty acids, elemental analysis, etc
• Growth medium design, supply (for lab and industrial scale) and optimization
53
• Growth medium design, supply (for lab and industrial scale) and optimization
for photo, mixo and heterotrophic growth
• Small group training in microalgae cultivation at A4F premises
• Contract research and development – at lab scale and pilot scale – strain
optimization, contamination control tools, biomass enrichment, etc
• Supply of pilot scale (kilogram) amounts of microalgae biomass
At the end of this stage it was possible to:
• External market study of microalgae for food and feed applications
• Develop a detailed and final Business Case for the industrial production unit
• Industrial production unit engineering design and construction
ALGAFARM PILOT
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ALGAFARM
ALGAFARM is the world’s largest unit of microalgae production with closed tubular photobioreactors – 1300m3 of Culture
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18th-22nd November 2013
LiMBAC
2nd Edition will give a larger emphasis to pilot pl ant cultivation techniques
13th – 18th November 2016
SAVE DATESAVE DATE
Venue: A4F, Algae For Future, SACampus do Lumiar - Edifício E, r/c Estrada do Paço do Lumiar 1049-038 Lisboa, PortugalPhone: +351 218072499Website: www.a4f.ptMore information: [email protected] and RegistrationThe course fee is 800 € (for students) and 1600€ (for non-students)It includes the course and all supporting material, daily commutes between A4F and hotel, coffeebreaks, lunches and one conference dinnerAccommodationDiscount rates for hotel accommodation will be announced shortly.
1st edition LIMBAC - Lisbon, in 2013:• Attracted 50 participants from 23 countries, with an average age of 32;• A very interactive programme, participants from 18 companies and 17 Universities;• Focused largely on lectures about case studies of microalgae businesses;• Practical Lab sessions about isolation, cultivation;• Biochemical analysis of microalgae cultures.
2nd edition LiMBAC
Lisbon, 13 th to 18 th November 2016
The 2nd edition of the LIMBAC aims tofamiliarize participants with advancedconcepts of microalgae cultivation with aspecial attention to scale-up processes, largescale cultivation and downstream processing.The course will take an interdisciplinaryapproach, presenting lectures covering thewhole microalgae value chain as well as laband pilot plant practical sections whereparticipants will have hands-on experience inculturing microalgae. The course is targetedto participants with some background andexperience in the microalgae field.
18th-22nd November 2013
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Vítor Verdelho with special thanks to Joana Lapa This presentation is the confidential work product of A4F AlgaFuel SA and no portion of this
presentation may be copied, published, performed, or redistributed without the express
written authority of a A4F Officer. © Copyright 2016, A4F AlgaFuel SA