Economical Reasons
Essential
• Energy Saver: • Decrease up to 100 kcal/kg of ME: Keep same FCR and ADG
• Improve ADG and FCR • AnDmicrobial Effect:
• Effects against gram posiDve bacteria: Clostridium perfringens (NE). • Effects against protozoa: Coccidiosis
• What are the energy effects of reducing NE or coccidiosis?
Broilers
• Energy Saver: • Decrease up to 90 kcal/kg of ME: Keep same producDon. • Decrease 3 g/day of the daily intake.
• AnDoxidant Effect: beRer persistency. • AnDmicrobial Effects:
• Effects against gram posiDve bacteria: Clostridium perfringens (NE). • Decreased mortality.
• What are the effects on energy and aminoacids when the microbial challenge is reduced?
Layers
• AnDmicrobial Effect: • Effects against gram posiDve bacteria: Clostridium perfringens (NE). • Effects against protozoa: Coccidiosis
• AnDoxidant Effect: • BeRer persistency. • BeRer hatchability.
Broiler Breeders
• Natural • No toxic residues in animal products • No negaDve interacDons
• No toxicity… (maybe this is client convincing!)
Nice… but not client convincing
AnDmicrobial • Protozoa • Gram PosiDve
DigesDon Enhancer • Energy Saver
AnDoxidant • BeRer ReproducDon • BeRer Carcass, Eggs
Essential
EssenDal Castor oil
Ricinoleic Acid
Cashew Nut Shell Liquid (CNSL)
Cardol Cardanol
Composition of Essential
Natural Divalent Ionophore • AcDvity against gram posiDve bacteria • AcDvity against protozoa
AnD-‐inflammatory • Downregulates EP3 receptors
Ricinoleic Acid
Natural Monovalent Ionophore • AcDvity against gram posiDve bacteria • AcDvity against protozoa
AnDoxidant
Cardol
AnDoxidant
Cardanol
Essential is conventional & natural 1. Tested levels of ricinoleic acid, cardol and cardanol.
2. Quality control of the Einal product. 3. Analysis of active compounds in the feed.
Synergistic Effect: Castor oil + CNSL
EssenDal
An#-‐inflammatory
An#oxidant An#microbial
A^er EssenDal
Healthy
Reddish
Integrity
Antimicrobial
Before EssenDal
Hemorragic
Yellowish
Petechia
Effects of Essential against three strains of Clostridium perfringens
Treatment CP 8-1 CP 8-2 CP 3-1
Control + + +
Essential - - -
(+) Bacterial growth; ( - ) No bacterial growth
Effects of Essential in broilers inoculated with E. acervulina, E. maxima and E. tenella (Lara et al., 2006)
Treatment Duodenum Ileum Cecum
Neg. Control 0.00 0.00 0.00
Neg. Control Inoculated 1.11a 1.17 1.78a
Salinomicin – Inoculated 0.72b 0.72 1.61a
Essential - Inoculated 0.67b 1.20 1.13b
abMeans in the same column with different superscripts differ P < 0.05
Intestinal lesion score of the birds 7 d after a coccidiosis challenge (21 d of age) with and without Essential supplementation.
a
b b
a
b b
abMeans with different superscripts are significantly different (P < 0.05).
Liveability (%) of the birds at 21 and 42 days of age with and without Essential supplementation.
3.40 2.24 SEM
96.25 97.33b + 2 97.08 98.00b - 2 93.33 97.33b + 1.5 95.83 97.00b - 1.5 96.25 87.33a + 0
21 to 42 days 1 to 21 days Liveability (%)
Challenge Suplementation, Essential, kg/ton
abMeans with a different superscript letter within a column are significantly different (P < 0.05)
Energy Saver
Nutrient extracDon Economic Benefit
BeRer DigesDon
BeRer AbsorpDon
Miroflora Improvement
IntesDnal mucosa
protecDon
Enzyme acDvity
sDmulaDon
Energy extracDon
IntesDnal Integrity
Feed conversion (g of feed/g of gain) for the birds with and without Essential supplementation at 7 and 14 d of age (pre-challenge)
a
b b
c
c d d
d d
abTreatments differ (P = 0.0001) cdTreatments differ (P < 0.02)
Treatment Weight @ 42 d, kg Intake, kg FCR FCR @ 2.5 kg Control-0 3.093a 5.120a 1.682ab 1.512a
Essential-0 3.207b 5.206ab 1.648ab 1.446b Control-100 3.046a 5.198a 1.734c 1.578c
Essential-100 3.182b 5.269bc 1.681ab 1.487ab Control-200 2.968c 5.260bc 1.801d 1.667d
Essential-200 3.066a 5.322c 1.763ce 1.601ce Essentialgf-100 3.160b 5.260bc 1.690b 1.502a Essentialgf-200 3.018ac 5.301bc 1.785de 1.637de Essentialf-100 3.054a 5.200a 1.731c 1.572c Essentialf-200 2.971c 5.262bc 1.800d 1.666d
Effects of Essential on diets with different levels of energy
y = 0.0074x + 0.1843
y = 0.0065x + 0.5185
y = 0.008x + 0.0307
y = 0.007x + 0.4353
2.85
2.90
2.95
3.00
3.05
3.10
3.15
3.20
3.25
3.30
355 360 365 370 375 380 385 390 395 400 405 410
Wei
ght G
ain,
kg
EM, kcal/d
Control 35-42 d 21-42 d Essential Linear (Control) Linear (35-42 d) Linear (21-42 d) Linear (Essential)
Effects of Essential on ME
Effect of Dietary Supplementation of Essential® and Pharmaceuticals on Breast Meat Drip Loss
P<0.10
Effect of Dietary Supplementation of Essential® and Pharmaceuticals on TBARS values
*Means differ P < 0.02
Essential -‐ Layers
Test Protocol-‐I ProducDon under heat stress
Strain: Bovans White
Ages: 23 weeks
Number of birds:
2.957 with EssenDal (1.5 kg/MT)
17.667 Control
Weekly Production under heat stress
Weekly average Week Essen.al Control 23 58,8 61,4 24 65,6 65,5 25 76,7 70,8 26 86,4 74,3 27 86,9 76,7 28 87,0 72,4 29 85,3 73,2 30 82,6 72,8 31 86,9 74,8 32 82,2 76,4
Average 79,84 71,83
Daily Production
50.0
55.0
60.0
65.0
70.0
75.0
80.0
85.0
90.0
95.0
1 3 5 7 9 11 13 15 17 19 21 23 25 27 29 31 33 35 37 39 41 43 45 47 49 51 53 55 57 59 61 63 65 67 69
ESSENTIAL PADRÃO
Weekly Production
58.8
65.6
76.7
86.4 86.9 87 85.3
82.6
86.9
82.2
79.84
61.4
65.5
70.8
74.3
76.7
72.4 73.2 72.8 74.8
76.4
71.83
40
45
50
55
60
65
70
75
80
85
90
23 24 25 26 27 28 29 30 31 32 média
% Produ
c#on
Weeks
EssenDal Padrão
Conclusão
• The group supplemented with EssenDal showed beRer producDon than the control
Test Protocol -‐ II Strain: Hy-‐Line
Age: 56 weeks
Number of birds:
17.767 – White
4.437 – Red
Dosage: 1.5 kg/MT
Production Data
Week Produc#on Standard Produc#on % produc#on Mortality %
55 83 77,4 -‐5,6 0,144
56 82 76,9 -‐5,1 0,302
57 82 83,4 1,4 0,379
58 81 79,4 -‐1,6 0,390
59 81 79,6 -‐1,4 0,146
60 81 80,7 -‐0,3 0,269
61 80 78,2 -‐1,8 0,200
Production & Mortality
77.4 76.9
83.4
79.4 79.6 80.7
78.2
0.144
0.302
0.379 0.390
0.146
0.269 0.200
0.000
0.050
0.100
0.150
0.200
0.250
0.300
0.350
0.400
0.450
50.0
55.0
60.0
65.0
70.0
75.0
80.0
85.0
90.0
95.0
100.0
55 56 57 58 59 60 61
Produção mortalidade %
Beginning of Essential Supplementation
End of Essential Supplementation
Pictures of 1st necropsy (09/09/2011)
1st necropsy
1st necropsy
Pictures of 2nd necropsy (30/09/2011)
2nd necropsy
2nd necropsy
Piictures of 3rd necropsy (12/10/2011)
3rd necropsy
3rd necropsy
Conclusion • The birds were already post-‐peak and below the standard curve when the treatment began.
• During the treatment there was an improvement in the laying %. • In week 61, a^er ending the supplementaDon of EssenDal, the producDon fell.
• Mortality was 50% lower a^er EssenDal supplemenDon compared to the rest of the farm.
Effects of Essential supplementation on broiler breeder performance (Brazil)
AnDmicrobial • Protozoa • Gram PosiDve
DigesDon Enhancer • Energy Saver
AnDoxidant • BeRer ReproducDon • BeRer Carcass, Eggs
Essential
Recommended
