Download pdf - Cyclins and Cell Cycle Regulation - Abcam · 2009. 6. 8. · Cyclins and Cell Cycle Regulation Cell decides whether to continue Cell prepares to divide Cell division (mitosis) Cycle

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Page 1: Cyclins and Cell Cycle Regulation - Abcam · 2009. 6. 8. · Cyclins and Cell Cycle Regulation Cell decides whether to continue Cell prepares to divide Cell division (mitosis) Cycle

Cyclins and Cell Cycle Regulation

Cell decideswhether tocontinue

Cell preparesto divide

Cell division(mitosis)

Cycle begins

Cell grows

Replicationof DNA

Cyclin E

CDK2

Rb dephosphorylation

Rb

phosphorylation

G2

M

G1

S

Cyclin B/A

CDK1/ CDC2

Cyclin A

CDK2

Cyclin D

CDK4,6

Cdk2 antibody (ab7954) ATM (phospho S1981)

antibody (ab2888)

p21 antibody (ab18209) p57 Kip2 antibody (ab4058)

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