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Page 1: Cours du 28 novembre 2011 - Collège de France · Ba: Synthec Ansens strategy ... by the number of synon- ymous changes (depicted in blue); a value greater than one is used as evidence

Cours du 28 novembre 2011

Page 2: Cours du 28 novembre 2011 - Collège de France · Ba: Synthec Ansens strategy ... by the number of synon- ymous changes (depicted in blue); a value greater than one is used as evidence

Page 3: Cours du 28 novembre 2011 - Collège de France · Ba: Synthec Ansens strategy ... by the number of synon- ymous changes (depicted in blue); a value greater than one is used as evidence

Page 4: Cours du 28 novembre 2011 - Collège de France · Ba: Synthec Ansens strategy ... by the number of synon- ymous changes (depicted in blue); a value greater than one is used as evidence

Page 5: Cours du 28 novembre 2011 - Collège de France · Ba: Synthec Ansens strategy ... by the number of synon- ymous changes (depicted in blue); a value greater than one is used as evidence

Page 6: Cours du 28 novembre 2011 - Collège de France · Ba: Synthec Ansens strategy ... by the number of synon- ymous changes (depicted in blue); a value greater than one is used as evidence

Page 7: Cours du 28 novembre 2011 - Collège de France · Ba: Synthec Ansens strategy ... by the number of synon- ymous changes (depicted in blue); a value greater than one is used as evidence

Page 8: Cours du 28 novembre 2011 - Collège de France · Ba: Synthec Ansens strategy ... by the number of synon- ymous changes (depicted in blue); a value greater than one is used as evidence

Page 9: Cours du 28 novembre 2011 - Collège de France · Ba: Synthec Ansens strategy ... by the number of synon- ymous changes (depicted in blue); a value greater than one is used as evidence

Page 10: Cours du 28 novembre 2011 - Collège de France · Ba: Synthec Ansens strategy ... by the number of synon- ymous changes (depicted in blue); a value greater than one is used as evidence

Page 11: Cours du 28 novembre 2011 - Collège de France · Ba: Synthec Ansens strategy ... by the number of synon- ymous changes (depicted in blue); a value greater than one is used as evidence

Ba: Synthe8c An8sens strategy

Bb: Sponge strategy

Aa: DNA demethyla8ng agents and histone deacetylase inhibitors

Ab: Delivery of µRNA

Ac: Enhancing DICER ac8vity

Page 12: Cours du 28 novembre 2011 - Collège de France · Ba: Synthec Ansens strategy ... by the number of synon- ymous changes (depicted in blue); a value greater than one is used as evidence

Page 13: Cours du 28 novembre 2011 - Collège de France · Ba: Synthec Ansens strategy ... by the number of synon- ymous changes (depicted in blue); a value greater than one is used as evidence

Page 14: Cours du 28 novembre 2011 - Collège de France · Ba: Synthec Ansens strategy ... by the number of synon- ymous changes (depicted in blue); a value greater than one is used as evidence

Page 15: Cours du 28 novembre 2011 - Collège de France · Ba: Synthec Ansens strategy ... by the number of synon- ymous changes (depicted in blue); a value greater than one is used as evidence

Page 16: Cours du 28 novembre 2011 - Collège de France · Ba: Synthec Ansens strategy ... by the number of synon- ymous changes (depicted in blue); a value greater than one is used as evidence

Page 17: Cours du 28 novembre 2011 - Collège de France · Ba: Synthec Ansens strategy ... by the number of synon- ymous changes (depicted in blue); a value greater than one is used as evidence

Page 18: Cours du 28 novembre 2011 - Collège de France · Ba: Synthec Ansens strategy ... by the number of synon- ymous changes (depicted in blue); a value greater than one is used as evidence

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