Clinical Presentation and Diagnosis of TuberculosisSlides from the web site http://www.tbrieder.org
Compiled by:
Hans L Rieder
Background of stained smears
Acid-alcoholdestainedsmear
Sulfuric aciddestainedsmear
Picture courtesy: Kim SJ. Unpublished Lecture Notes, Hanoi, August 31, 2001
a
b
c
Sturisoma festivum
Picture courtesy: Van Deun AJune 13, 2004
The Sites of Vertebral Tuberculosis
Paradiscal
Central
Anterior
Posteriorappendicial
PosteriorFacet joints
Tuli SM. Clin Orthopaed 2002;398:11-9
Posteriorappendicial
Affected Vertebrae in Spinal Tuberculosis
Cervical
Thoracic
Lumbar
Sacral
Chen WJ, et al. Acta Orthop Scand 1995;66:137-42
From: http://www.chirogeek.com/000_Disc_Anatomy.htm
Anatomy and the Nutrition of the Intervertebral Disc
Anterior Posterior
Pathogenesis of Tuberculosis of the Spine
De Vuyst D. Eur Radiol 2003;13:1809-19
Osseous Tuberculous Foci in the Hip
Acetabular
Epiphyseal
Trochanteric
Metaphyseal
Tuli SM. Clin Orthopaed 2002;398:11-9
At diagnosis After 2 months
Mycobacterium tuberculosis Bacteremia inFebrile Patients in Dar es Salaam, Tanzania
Per
cen
t
0
5
10
15
20
25
HIV neg
HIV pos
Archibald LK, et al. Clin Infect Dis 1998;26:290-6
died
survived
Donald PR, et al. N Engl J Med 2004;351:1719-20
Change in cerebrospinal fluid findings in a child with tuberculous meningitis
Date White cell count
Polynuclear (%)
Mononuclear (%)
Protein Sugar
26 July 9 - - ++ 0
27 July 213 71 29 +++ 0
30 July 509 16 84 +++ 0
Tuberculous Chorioretinitis
Lanzafame M, et al. Lancet 2001;357:1390
Response to chemotherapy of tuberculosis verrucosa cutis
At diagnosis After 1 month After 3 months