Download pdf - ChemInform Abstract: 1-Alkyl-2,4-dihydro-1H-pyrazino[2,1-b]quinazoline-3,6-diones as Glycine Templates. Synthesis of Fiscalin B

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Page 1: ChemInform Abstract: 1-Alkyl-2,4-dihydro-1H-pyrazino[2,1-b]quinazoline-3,6-diones as Glycine Templates. Synthesis of Fiscalin B

2002 pyrazine derivatives

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34 - 1731-Alkyl-2,4-dihydro-1H-pyrazino[2,1-b]quinazoline-3,6-diones asGlycine Templates. Synthesis of Fiscalin B. — The regioselectivealkylation of the title compounds (I) and (V) proceeds diastereoselectively inthe case of (V). Product (IIIe) can be used for the preparation of fiscalin B.— (HERNANDEZ, FERNANDO; BUENADICHA, FELIX L.; AVENDANO,CARMEN; SOELLHUBER, MONICA; Tetrahedron: Asymmetry 12 (2001) 24,3387-3398; Dep. Quim. Org. Farm., Fac. Farm., Univ. Complutense, E-28040Madrid, Spain; EN)

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