BUSINESS OPPORTUNITIES IN BIOTECHNOLOGY IN INDIA
P. K. Ghosh, Ph DManaging Director
KEE GAD Biogen Pvt. Ltd., New Delhi
(Former Adviser DBT, GOI)
March 06, 2009
INDIAN EFFORTS TO SUSTAIN EMINENCE IN BIOTECHNOLOGY: MOSTLY A GOVERNMENT EFFORT
Government Departments DBT DST DSIR DRDO DOE & Others
Autonomous Institutions CSIR ICAR ICMR UGC/AICTE Institutions Other Institutions
P. K. Ghosh
INDIAN BIOTECH IN GLOBAL CONTEXT
Publications and Patents filings on the rise
Leadership in innovation is yet narrow
R&D Institutes & Universities low in Global ranking
Research in Industry not significant yet
Innovation and Application not strongly linked
Academia not ready to take risk for a venture
P. K. Ghosh
HEALTH & WEALTH: INDEX FOR DEVELOPMENT
A Country is highly developed if it has……
Break through remedies for major diseases like:
Cardiovascular diseases
Cancer
Viral Diseases
Killer Bacterial Diseases
Abundant availability of Clothing, Food & Drinking water
Sound Knowledge and Practice of good Hygiene
High Quality Jobs
Technologically Advanced Industries
In all the above areas Biotech can make a contribution….
P. K. Ghosh
SKILLS THAT REVOLUTIONIZED BIOTECHNOLOGY
rDNAs & MAbs
Microscopy and Imaging
Proteins & Nucleotide sequencing
PCR Technology
LC-MS & MALDI-TOP
Flow-cytometry & Cell Sorting Techniques
Chromatography & Electrophoresis
Protein & DNA Chips & Microarrays
Bio-Informatics
P. K. Ghosh
TOP CONCERNS OF INDIAN BIOTECH INDUSTRY
Scarce availability of leaders for company specific needs
Inadequate availability of skilled work force
Limited resources for research- Internal & External
Maintenance of Confidentiality
Issues of Intellectual Property
Bridging issues between R&D Institutions & Industry
Demanding statutory requirements
Biased concerns about products by opinion makers
Limited linkage between Industry need & Public research
P. K. Ghosh
BENEFITS OF TECHNOLOGY TRANSFER BY R&D INSTITUTES
To push discovery into the market
To attract Funding & Industrial Partnership
Budding skills can be placed into rewarding projects
To earn rewards through income & fame
Obliged to be transparent by disclosers – Projects, Employees, Sponsors etc.
Economic development and Societal uplift
P. K. Ghosh
BIOTECH APPLICATIONS
Health Care Agriculture
Environment Industry
GM- Planting Mats. & Hybrids
Micro-propagation
Bio-fertilizers & Bio-pesticides
Animal Improvement
r-DNA Products, Vaccines & Diagnostics Monoclonal Antibodies
Stem CellsTissue Specific delivery methods
Enzymes Fermentation based Products & Food
Biotech Instruments & Equipment Bio-energy & Bio-fuel
BioinformaticsBio-mining
Soil & Water remediationBio-safety & GMOs
P. K. Ghosh
BUSINESS OPPORTUNITIES: HEALTH CARE
rDNA Products & MAbs Cloning, Cell multiplication, Product separation & Formulations
Choice of technologies
Stem Cell Manipulation Isolation, purification & multiplication of tissue specific stem cells
Expertise in Cell re-programming to pluripotency
Over expression of certain Genes for Cell re-programming
Retro & Non-retroviral means of over expression of target genes
Tissue Specific Delivery Technologies Choice of Bio-degradable polymers & modification methods
Choice of technologies for production of precise Nano-particles
P. K. Ghosh
BUSINESS OPPORTUNITIES: AGRICULTURE
GM- Seeds: Varieties & Hybrids Choice of right materials
Cloning, Micro-propagation & Field Testing
Generation of Food & Environmental Safety Information
Extensive Public-Private Collaboration involving Opining Makers
Animal Improvement Land & Aquatic Animals Identification for Multiplication
Choice of Exotic Animal germplasm & Multiplication methods
Feed & Fodder Production technologies
P. K. Ghosh
BUSINESS OPPORTUNITIES: INDUSTRY & ENVIRONMENT
Industry r-DNA methods of producing Enzymes
Fermented Food & Beverages
Software Development for use in Biotech operations
Biotech Instruments through Electronics, Software & New Materials
Biomass Multiplication & Bio-fuel
Environment Biosafety Information generation for commercial use of GMOs
Degraded/ Polluted Soil & Water Remediation methods
P. K. Ghosh
BIOTECH PRODUCT DEVELOPMENT TREND
Drugs & Pharmaceuticals for Human
Isolating/Developing & Multiplying Totipotent Stem Cells
Genetically Modified Seeds for Agriculture
Instruments for Biotechnology
Bioinformatics
P. K. Ghosh
Biotech drugs innovation process
New Idea/ Research
Proof of Concept
Pilot Development
Production Unit setting up &
implementation into valuable form
Marketing feedback analysis
Animal Studies
Phase I, II, III Studies
Marketing Strategy
Time (Years)
Act
ors
05 10 15
R&D Institutes
Technology Development & Transfer
Strong Industry Motivation for Success
Regulatory Approval
Mon
ey S
pent
WHAT ARE THE SURVIVAL LANES?
To Intensify Basic Research
To Develop Novel Methods for Bio-generics
Mass Production of Multivalent Vaccines
Mass Production of Cheap Diagnostics
Novel Drug Delivery & Nanotechnology
GM Varieties from Public Institutions
Micro-propagation of elites
Industrial Enzymes by r-DNA technology
Mass Composting of wastes
Enzyme Enriched Food & Neutraceuticals
Bio-energy & Bio-fuels
P. K. Ghosh
THANK YOU
Turbulence ahead…
P. K. Ghosh