BIOC223 – FUNDAMENTALS OF BIOCHEMISTRY

Carbohydrate Unit Objectives- Students will be able to C1. Collect/obtain biochemical information from a variety of credible sources about carbohydrates and present them using discipline appropriate representation.C2. Describe specific chemical and physical properties/ features of a carbohydrate and correlate elements of carbohydrate nomenclature and terminology with its structure. C3. Given the name or chemical formula of a carbohydrate, draw both the Fisher and Haworth representations of the carbohydrate and compare and contrast the two representations. C4. Given the structure of a carbohydrate identify functionally important chemical features and evaluate their roles in molecular recognition.C5. Given the structure of a carbohydrate identify the covalent bond that joins the monomer units and notate key features of the bond or macromolecule.C6. Given the structure of a carbohydrate predict the impact of chemical reactions and/or altering physical and chemical characteristics of the environment on the structure, physicochemical properties, and the function of the carbohydrate and evaluate their impact on molecular recognition.C7. Given the structure of a chemically modified carbohydrate, identify the chemical modifications and the modifying chemical reaction or given a specific chemical reaction create a modified carbohydrate.C8. Given the structures and functions of a variety of carbohydrates provide a chemical/mechanistic explanation to how carbohydrates perform a diversity of functions within biological systems by contextualizing specific structural features to explain specific functions.C9. Given the structure of a carbohydrate or a carbohydrate binding another compound/macromolecule, identify and analyze forces involved in intra- and inter-molecular interactions.C10. Given a figure and/or text depicting the key structural features of a macromolecular assembly involving carbohydrates, hypothesize forces stabilizing the structure and design an experimental test to evaluate the potential contributions of each force to stabilizing its structure.

Overarching Objectives – Students will be able toO1. Find, analyze, discuss, and evaluate scientific content in a primary literature or scientific text that addresses a biochemical problem or claimO2. Demonstrate effective and productive teamworkO3. Communicate biochemical concepts to people within (peers and professor)and outside (public) the field.

WEEK7: First week of a two-week carbohydrates unit

Reading (text book) 1

2 Concept Check: C1a, C2,C4

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5

Worksheet 1a: O2, O3, C2, C4

4 Interactive lecture (new material)

6 Think-pair-share question: O2, O3,C2, C3

7 Wrap-up question: C2, C4

Worksheet 1b: O2, O3 C3, C6a

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Clicker Questions: C2-C7

Worksheet 2a: O2, O3, C7

Worksheet 2a: O2, O3, C6,C7

MCAT passage: O1, C5, C6

Think-pair-share question: O2, O3,C6, C8-10a

Class Google Doc: O2, C1

Reading (Hidari et.al 2010) 15

16Interactive lecture (new material)

Interactive lecture (based on Hidari 2010)

17 Worksheet 3: C8,C9,C10

18 Carbohydrate Assignment:Weis et. al, 1988 O1, O3, C1-C10

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Student Work not assessment

Individual assessmentParticipation/ Formative

Professor Work not assessment

Group assessmentParticipation/ Formative

Individual assessmentLow Stake/ Formative

Individual assessmentHigh Stake/ Summative

in-classactivities

out-of-class activities

4 9

3TUE WED FRI

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2

MON THUSAT& SUN

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