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Page 1: Basal Ganglia - University of Washington · 2011-12-23 · Basal Ganglia Emo Todorov Applied Mathematics Computer Science and Engineering Universityyg of Washington Loops with cortex

Basal Ganglia

Emo Todorov

Applied MathematicsApplied MathematicsComputer Science and Engineering

University of Washingtony g

Loops with cortex 2

Page 2: Basal Ganglia - University of Washington · 2011-12-23 · Basal Ganglia Emo Todorov Applied Mathematics Computer Science and Engineering Universityyg of Washington Loops with cortex

Subdivisions 3

Circuit diagram 4

Page 3: Basal Ganglia - University of Washington · 2011-12-23 · Basal Ganglia Emo Todorov Applied Mathematics Computer Science and Engineering Universityyg of Washington Loops with cortex

Recurrent connections with cortex 5

Cortical targets

Specificity or recurrent connections 6

Page 4: Basal Ganglia - University of Washington · 2011-12-23 · Basal Ganglia Emo Todorov Applied Mathematics Computer Science and Engineering Universityyg of Washington Loops with cortex

Imbalance of excitation and inhibition 7

Parkinson’s movements are mostly normal 8

Page 5: Basal Ganglia - University of Washington · 2011-12-23 · Basal Ganglia Emo Todorov Applied Mathematics Computer Science and Engineering Universityyg of Washington Loops with cortex

Imbalance of excitation and inhibition 9

Broad suppression and local facilitation 10

Page 6: Basal Ganglia - University of Washington · 2011-12-23 · Basal Ganglia Emo Todorov Applied Mathematics Computer Science and Engineering Universityyg of Washington Loops with cortex

Coding of reward by dopamine neurons 11

(Schultz)

Coding of relative reward magnitude 12

Page 7: Basal Ganglia - University of Washington · 2011-12-23 · Basal Ganglia Emo Todorov Applied Mathematics Computer Science and Engineering Universityyg of Washington Loops with cortex

Coding of reward uncertainty/risk 13

Learning effects on spatial coding 14