LINK + LICENSE + LAUNCHTECHNOLOGY HIGHLIGHT
CONTACT:
Grant [email protected]
THE CHALLENGE
OUR SOLUTION
PRC1584 (grey) as effective as Chloroquine (orange).
HCL salt of compound for ease of oral formulation.Paul Carlier and team have created a structurally novel compound that inhibits the growth of malaria parasite in red blood cells. It is non-toxic to human cells suggesting parasite targeting mechanism of the compound. It can even be orally administered without any gastro-intestinal distress.
It shows an efficacy similar to that of chloroquine with added efficacy against drug resistant strains, thus a superior drug
While current malarial drugs are able to protect against some
strains, new malarial drugs are urgently needed to combat drug resistant malaria infection.
Also current malarial drugs cannot be administered orally, which
reduces the potential for safe drug delivery.
A Novel Orally Administered AntimalarialVTIP 20-048: “Discovery of an Orally-Active Tetracyclic Antimalarial”
PRC1584