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Zoo-352 Principles of genetics Lecture 3 The cell cycle and its checkpoints

Zoo-352 Principles of genetics Lecture 3 The cell cycle and its checkpoints

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Page 1: Zoo-352 Principles of genetics Lecture 3 The cell cycle and its checkpoints

Zoo-352 Principles of geneticsLecture 3

The cell cycle and its checkpoints

Page 2: Zoo-352 Principles of genetics Lecture 3 The cell cycle and its checkpoints

Structure of chromosome

Page 3: Zoo-352 Principles of genetics Lecture 3 The cell cycle and its checkpoints

Schematic of Submetacentric chromosome

Page 4: Zoo-352 Principles of genetics Lecture 3 The cell cycle and its checkpoints

CentromereJoins two sister chromatids together

Dark (G) bands Contain condensed chromatin (Heterochromatin)

Light (G) bands Less condensed chromatin (Euchromatin)Telomere

Telomere

Page 5: Zoo-352 Principles of genetics Lecture 3 The cell cycle and its checkpoints

Classification of chromosomes

Page 6: Zoo-352 Principles of genetics Lecture 3 The cell cycle and its checkpoints

A pair of homologous chromosomes (number 1)

Locus (position of a gene)

Allele (alternative form of a gene)

Page 7: Zoo-352 Principles of genetics Lecture 3 The cell cycle and its checkpoints

Karyotype of a human female

Page 8: Zoo-352 Principles of genetics Lecture 3 The cell cycle and its checkpoints

Karyotype of a human male

• Chromosomes are made of DNA and protein.

• Each contains genes in a linear order.• Human body cells contain 46

chromosomes in 23 pairs – one of each pair inherited from each parent

• Chromosome pairs 1 – 22 are called autosomes.

• The 23rd pair are called sex chromosomes: XX is female, XY is male.

Page 9: Zoo-352 Principles of genetics Lecture 3 The cell cycle and its checkpoints

Quiz - Chromosome Structure, Karyotypes

1. A human being has _____ autosomes and ______ sex chromosomes

23, 1

22 pairs, 1 pair

23, 23

2, 2

2. A section of chromosomes that codes for a trait can be called a(n):

nucleotide

base-pair

gene

nucleus

3. Somatic cells of a human have ____ chromosomes and are called ____

10, haploid

92, diploid

23, haploid

46, diploid

4. Each chromosome consists of two identical:

genes

nuclei

chromatids

bases

Page 10: Zoo-352 Principles of genetics Lecture 3 The cell cycle and its checkpoints

5. If a person receives an X and a Y chromosome, that person is:

female

male

red eyed

mentally challenged

6. Two alleles for pea plant height are designated T (tall) and t (dwarf). These alleles are found on:

genes

sex chromosomes

ribosomes

homologous chromosomes

7. An animal has 40 chromosomes in its gametes, how many chromosomes would you expect to find in this animal's brain cells?

1

20

40

80

8. A picture of a person's chromosomes is called a(n):

karyotype

syndrome

chromatin

fingerprint