Rapid tests

Laboratory diagnostics

Laboratory service

Consultation & service

Analysis of 4 key factors: pH, concentration, morphology and motility

Precise and reliable results in minutes – only 3 steps required

Patented analysis: Robust and efficient

X1 PRO Semen Quality Analyzer Simple, intuitive, reliable

The professional point-of-care solution for reliable sperm analysis in lab quality

The smallest

fully automated

sperm analysis

device in the world!

Sperm analysis in lab qualitySemen Quality Analyzer – simple, intuitive, reliable

Use your valuable time for patients instead of time-consuming phone calls, test analyses or administrative tasks. The Semen Quality Analyzer is simple to use, and offers you comprehensive, auto-mated results in just a few minutes.

With the help of this patented semen quality analyzer, a variety of sperm-related parameters can be evaluated within your practice. Results are available in no time at all – and all in lab quality! Lengthy waits, time-consuming test analyses and patient follow-up appointments are no longer necessary, saving both you and your patient valuable time and easing the administrative workload.

· Semen Quality Analyzer

Intuitive

• Simple procedure

• Easy touchscreen operation

• Standardised process

• Time and personnel-saving analysis

• Fully automated analysis process

• Clear, printable patient reports

• Connects to tablets and monitors

Your benefits with the Semen Quality Analyzer

Simple

• Sperm analysis in 3 intuitive steps

• Test results within 3-5 minutes of liquefaction process

• No sample preparation required after liquefaction process

• HDMI connection

• LAN connection

• No need to send samples to the lab

• No waiting for test results

Fast and simple: 3-step test procedure takes just 3-5 minutes

Interpret test results.Dispense a drop of the patient sample into each sample well of the test cassette.

Insert the test cassette – with test fields facing to the front – into the cassette port.

1. 3.2.

Click!

14 cm

7 cm

7 cm

Page 3

Reliable

• Results in lab quality

• CE-certified

• FDA-certified

• Automated sample processing ensures high level of precision

• Robust algorithms for high accuracy

• Controls available

• CASA report for each analysis

• Video material for patients

· Semen Quality Analyzer

Precise evaluation of sperm analysis parameters Method comparison for selected parametersThe Semen Quality Analyzer provides measurement results with the help of a quantitative analysis method, which evaluates the pH levels, concentration, motility and morphology of semen. Comparison with established laboratory methods has demonstrated equality between the processes.

Above: Comparison between correlation results of sperm concentration using the LensHooke™ Analyzer and a manual microscopic method. The continuous blue line represents the regression line, the dotted red line represents the diagonal line and the black dashed line portrays the confidence line (n=135).

Correlation analysis Pearsons correlation coefficient

Correlation analysis (Overall sperm motility) Pearsons correlation coefficient

Deviation analysis Bland-Altman Analysis

Correlation analysis (Progressive motility)Pearsons coefficient

Above: Comparison between the overall motility results between the LensHooke™ Analyzer and a manual microscopic method (n=100). As shown in the small graph, the overall correlation between the motile sperm concentration (MSC) is r = 0.97.

Above: Bland-Altman Analysis of the concentration deviation results between the LensHooke™ Analyzer and a visual-manual microscopic method. The continuous black line is the mean difference between the methods, and the black dashed lines show the 95 percent confidence interval.

Above: Comparison of the progressive motility results between the LensHooke™ Analyzer and a visual-manual microscopic method (n=100). As shown in the small graph, the total correlation between the progressive motile sperm concentration (PMSC) is r = 0.94.

Concentration

Motility

Sperm concentration (million/mL) Manual sperm analysis

y = 0.96xr = 0.97

200

150

100

50

00 20015010050Sp

erm

con

cent

ratio

n (m

illio

n/m

L)

X1 P

RO

Average concentration (million/mL) Manual sperm analysis vs. X1 PRO

Sper

m c

once

ntra

tion

(mill

ion/

mL)

M

anua

l spe

rm a

naly

sis v

s. X

1 PR

O 200

+1.96 SD

17.2

150

100

50

005 200 250 3001501000

-1.96 SD

Mean-2.0

-21.2

200

200

160

160

120

120

80

80

40

400

0

Ove

rall

sper

m m

otilit

y (%

)X1

PRO

Overall sperm motility (%) Manual sperm analysis

0

20

40

60

80

100

0 20 40 60 80 100

y = 0.94x - 2.34r = 0.96

MSC

MSC_Manual

MSC

_X1

PRO

160

160

128

128

96

96

64

64

32

320

0

Prog

ress

ive

moti

lity

(%)

X1 P

RO

Progressive motility (%) Manual sperm analysis

0

20

40

60

80

100

y = 0.94x + 3.99r = 0.87

0 20 40 60 80 100

PMSC

PMSC_Manual

PMSC

_X1

PRO

Page 5

3.

• All-in-one patented sampling container and liquefaction process• Measurement scale to ensure sufficient sample material• Integrated dropper system• Reduced risk of coming into contact with sample material• Avoids contamination of sample materials

The C-KUP™ Liquefaction Test CupThe innovative 3-in-1 sample preparation system

Your benefits at a glance:

Built-in dropper system eliminates need for additional pipetting steps.

Integrated measurement scale to ensure sufficient sample quantity.

Patented V-stick design to check sample fluidity.

1.

min.

2.

• Only a minimal amount of sample material required • Patented dual-chamber test principle with integrated protection against leakage• Utilises a high-quality optical system for reliable test results • Concave design makes opening the test cassette easy • Separate test regions for pH measurement and the evaluation of concentration, motility and morphology

The LensHooke™ Semen Test CassetteFor a simple sperm analysis procedure

Your benefits at a glance:

Lens material inspired by smartphone cameras enables complete transparency as well as a low turbidity factor.

To carry out the test, each test chamber requires only one drop of sample material.

Patented concave design with anti-leak function prevents acci-dental sample contamination.

0.04 mL

1. 2. 3.

· Semen Quality Analyzer

Product Description Product code

LensHooke™ X1 PRO Semen Quality Analyzer

Analyzer for the evaluation of sperm test cassettesSet consists of: 1x LensHooke™ X1 PRO Semen Quality Analyzer1x power cable1x instructions for use

1830300

Product overview

Technical data

Product Description Product codeLensHooke™ Semen Test Cassette

Set consists of: 50x LensHooke™ Semen Test CassettesFor carrying out sperm analysis

1830301

C-KUP™ Liquefaction Test Cup

Set consists of 10x C-KUP™ Liquefaction Test CupsCup for sample collection and liquefaction process

1830302

LensHooke™ Semen Test Cassette & C-KUP™

Set consists of:50x LensHooke™ Semen Test Cassettes50x C-KUP™ Liquefaction Test Cups

1830305

LensHooke™ Cleaning Wipe Set consists of:10x swabs for cleaning device

1830303

LensHooke™ X QC Beads (semen control kit)

Set consists of:1x 2 mL control level 11x 2 mL control level 21x 2 mL negative control

1830304

Barcode scanner Handheld barcode scanner incl. holder; connection via USB 770015

Semen Quality Analyzer Accessories

LensHooke™ X1 PRO Semen Quality AnalyzerControl panel 8.5 cm touchscreen

Power 100-240 V AC, 50-60 Hz, 0,5 A; Output: 5V DC, 2A

Battery life 3.7 V DC / 2.5 Ah

Internal storage capacity 30 patient reports including data and images

Detection time 2-5 min (depending on sample consistency)

Dimensions 7 x 14 x 7 cm

LensHooke™ Semen Test CassettepH pH 6.0-8.0 (in 0.2 pH measurement steps)

Concentration < 0.1-300 (10⁶/mL)

Motility (PR+NP, Total) < 1-100 %

Normal morphology < 1-100 %

Semen Quality Analyzer

Page 7

Headquartersnal von minden GmbH · Carl-Zeiss-Strasse 12 · 47445 Moers · GermanyChief Executi ve Offi cers: Sandra von Minden · Roland Meißner · Thomas ZanderCommercial reg. Kleve · HRB 5679Tel.: +49 941 290 10-0 · Fax: +49 941 290 10-50

info@nal-vonminden.comwww.nal-vonminden.com

We help you care!We help you care!

Our customer service team is on hand to answer any questi ons you may have by telephone, via email or in a personal consultati on. For details on your local sales offi ce and regional free phone numbers, visit www.nal-vonminden.com.

Rapid Tests

Laboratory Diagnosti cs

Laboratory Service

Consulti ng & Service

Rev0

1.01

/EN

45en

0000

7Re

v01.

03/X

X074

5en0

0001

The nal von minden all-round serviceWhether you have questions relating to our product range or offers, our consultants are happy to help. Your satisfaction is our priority. We offer you an all-round service package with comprehensive consultation, a simple ordering process and fast delivery - all at attractive prices. We would also be happy to visit you in your practice for a more in-depth consultation.

Do you have any questions about our semen quality analyzer? Are you interested in automated measurement and sperm analysis within your practice? Should you have any enquiries, we are ready to provide you with help and advice.

As your long-term partner, we don't just want to satisfy you - we want to inspire you, too!

For more detailed information, give us a call on our central number +49 (0)941 29010-0 or email us at semen-analysis@nal-vonminden.com. We look forward to hearing from you!

Your nal von minden team

semen-analysis@nal-vonminden.com +49 (0)941 29010-0

Contact

RegensburgFriedenstrasse 32, 93053 Regensburg Tel.: .....................+49 941 290 10-0 Fax: .....................+49 941 290 10-50

GöttingenRobert-Bosch-Breite 23, 37079 Göttingen Tel.: .....................+49 551 270706-99 Fax: .....................+49 551 270706-50

GermanyDeutsch:Gratis-Tel.: .....................0800 832 164Gratis-Fax: .....................0800 837 476

Français: Numéro gratuit: .............0800 564 720Fax gratuit: ....................0800 837 476

Italiano:Numero verde: ............0800 832 2146Fax gratuito: ..................0800 837 476

SwitzerlandViennaGratis-Tel: ......................0800 291 565Gratis-Fax: .....................0800 298 197

AustriaContact us: