Upload
phamthien
View
214
Download
1
Embed Size (px)
Citation preview
we
Program
regeneration
world conference on regenerative medicine [Germany | Leipzig 2011 | November 2–4, 2011]
02 World Conference on Regenerative Medicine, November 2–4, 2011
F r a u n h o F e r I n s t I t u t e F o r C e l l t h e r a p y a n d I m m u n o l o g y I Z I
We transfer biomedical research into the clinic
The Fraunhofer Institute for Cell Therapy and Immunology IZI investigates and develops solutions to specific problems at the interfaces of medicine, life sciences and engineering.
The Institute develops, optimizes and validates methods and products for the Business Units Drugs, Cell Therapy, Diagnostics and Biobanks.
To our clients and partners from the pharmaceutical, biotechnological and medical technology industry, diagnostic laboratories, clinical units and research facilities we offer complete solutions ranging from market studies right down to the development of a market-ready product and its marketing authorization.
www.wcrm-leipzig.com \\ 03
table of Contents
table of Contents
Welcome Address 05
Advisory Board 07
Overview Conference Venue 08
Program
Program at a Glance 10
Wednesday, November 2, 2011 12
Thursday, November 3, 2011 20
Friday, November 4, 2011 32
Special: Veterinary Medicine Program 44
Fraunhofer Life Science Symposium 47
Poster Presentation
Overview Poster Exhibition 51
Posters 52
Evening Functions 67
Exhibitors 70
Media Partners 72
Partners and Sponsors 72
Endorsing Partners 75
Special: Companies in Saxony 77
General Information 81
\\
\\ \\ \\
\\ \\ \\ \\ \\ \\
\\ \\
\\
\\ \\ \\ \\ \\
\\
04 World Conference on Regenerative Medicine, November 2–4, 2011
welCome address
Prof. Dr. Annette SchAvAn
Regenerative medicine is one of the most promising fields of biomedical research. By mobilizing the human body’s self-healing powers, it offers hope for many patients with diseases or injuries that were previously
difficult or even impossible to treat. Moreover, we expect regenerative medicine to provide new ways of compensating for deteriorating organ function in age-related diseases. This is particularly important against the backdrop of demographic change and the scarcity of donor organs. Regeneration technologies also have the potential to advance the development of testing methods for the pharmaceutical and chemical industries in order to establish alternatives to animal experiments.
Gentle and lasting healing – that is the strategy of regenerative medicine, and of the researchers working in this field in science and industry around the world. The World Conference on Regenerative Medicine 2011 in Leipzig offers researchers an opportunity to exchange views on the latest developments. Meetings of this kind are becoming increasingly important in such rapidly growing and interdisciplinary fields as regenerative medicine. They are another sign that Germany has become an internationally recognized leader in the field of regenerative medicine. Researchers at universities and hos-pitals and the numerous small and medium-sized companies operating in the fields of
biotechnology and medical technology have made a significant contribution to this.
The Federal Government has been supporting this development since the late 1990s by invest ing in basic and application-oriented research in science and industry. Between 1999 and 2007 alone, the Federal Ministry of Education and Research earmarked more than 60 million euros for funding initiatives in areas such as stem cell research, cell-based therapies, and tissue engineer ing. Moreover, funding is being provid ed for Translational Centres in Berlin, Leipzig, Hanover, Dresden, Tübingen/Reutlingen, Rostock and Heidelberg.
We are strengthening the networking of German research locations with experts from around the world through joint international calls for proposals. We want to ensure that scientific findings do not just lead to high-level publications, but that patients benefit from the achievements of regenerative medicine as well.
I would like to thank the organizers of the World Conference on Regenerative Medicine 2011 – the Translational Centre for Regenerative Medicine and the Fraunhofer Institute for Cell Therapy and Immunology – for their hard work. I hope that this conference gives all participants an opportunity to engage in a lively exchange of ideas and to gain new insights that will benefit patients.
Prof. Dr. Annette Schavan, MdBFederal Minister of Education and Research
www.wcrm-leipzig.com \\ 05
welCome addresses
Bringing together ex-perts from the diverse and interdisciplinary branches that focus on regenerative medi-cine is one main goal of the World Con-ference on Regenera-tive Medicine 2011. Cooperation between basic research, en-
gineering and clinical medicine is a prerequisite for realization of new treatment and therapy approaches for degenerative diseases. Solu-tions to the problems provided by each of the involved parties must be integrated to answer the following questions: Which underlying cell mechanisms must be considered? How can damaged tissue be reconstituted? Which legal hurdles exist prior to market launch of regenera-tive medicine products? The World Conference on Regenerative Medicine has succeeded in combining the different disciplines of regenera-tive medicine. Consequently, a rapidly growing number of participants from many disciplines attend World Conference on Regenerative Medicine which meanwhile has become one of Europe´s largest and most interdisciplinary conferences in this field.
welCome address
Prof. Dr. frAnk emmrich
The backdrop for the World Conference on Regenerative Medicine 2011, which takes place 02–04 November, is the city of Leipzig. The conference is organized by the European and International networks of Regenerative Medicine together with numerous scientific societies coordinated by the regional hosts namely the Fraunhofer Institute for Cell Therapy and Immunology and the Translational Centre for Regenerative Medicine of the University of Leipzig. Following the establishment of Leipzig as international location for regenerative medicine, the organizers intend to continue this successful tradition in 2013.
In addition to its excellent biotechnological and medical infrastructure, Leipzig has the charm to make your stay a unique experience. Discover the famous old city centre with the famous St. Thomas Church, the distinctive old city hall, awesome passages and take a look at the new emerging university building. I am delighted to welcome you to Leipzig and wish all of us interesting days with top-class, beneficial presentations and lasting impressions of both the conference and Leipzig. I hope the World Conference on Regenerative Medicine 2011 will facilitate diverse cooperation and open new horizons between clinicians, industry and researchers active in the field of regenerative medicine.
Prof. Dr. Frank EmmrichConference President
06 World Conference on Regenerative Medicine, November 2–4, 2011
Translational Centre for Regenerative Medicine (TRM) Leipzig
Translational Research
Research Services
Educational Services
The Translational Centre for Regenerative Medicine (TRM) of the Universität Leipzig was founded with the mission to efficiently translate research results of regenerative medicine into clinical application.
Currently the TRM Leipzig supports eight basic research teams, sixteen teams in the preclinical phase and three teams conducting clinical trials.
Research Areas and Key Technologies• TissueEngineeringand
MaterialsScience• CellTherapiesforRepairand
Replacement• RegulatoryMoleculesand
DeliverySystems• Imaging,Modellingand
MonitoringofRegeneration
Research Services• QualityManagement• CellAuthentication• ImageProcessing• MicrosurgeryandAnimalModels
TRM LeipzigPhilipp-Rosenthal-Str. 5504103 LeipzigGermany
Tel: +49 341 9739600Email: [email protected]
Anzeige WRM-Heft2011_V4.indd 1 30.09.11 09:18
www.wcrm-leipzig.com \\ 07
information
advisory board
Keynote sPeaKers
Buckler, Lee R., Cell Therapy Group – REGENMED INDUSTRY CONSULTING, Langley,
Canada \\ Dhein, Stefan, Universität Leipzig, Clinic for Heart Surgery, Leipzig,
Germany \\ Emmrich, Frank, Fraunhofer Institute for Cell Therapy and Immunology
IZI and Translational Centre for Regenerative Medicine (TRM), Leipzig, Germany \\ Haverich, Axel, Hannover Medical School, REBIRTH – Cluster of Excellence, Hannover,
Germany \\ Hutmacher, Dietmar W., Queensland University of Technology, Brisbane,
Australia \\ Kohler, Konrad, Universität Tübingen, Center for Regenerative Biology
and Regenerative Medicine, Tübingen, Germany \\ Magin, Thomas, Universität
Leipzig, Translational Centre for Regenerative Medicine, Leipzig, Germany \\ Mason, Chris, University College London, Advanced Centre for Biochemical Engineer-
ing, London, UK \\ Meisel, Hans-Jörg, BG-Clinic Bergmannstrost, Department
of Neurosurgery, Halle, Germany \\ Skutella, Thomas, University of Heidelberg,
Institute for Anatomy and Cell Biology, Heidelberg, Germany \\ Walles, Heike,
Julius-Maximilian-Universität Würzburg, Chair for Regenerative Medicine, Würzburg
Allsopp, Tim, UK \\ Blunn, Gordon, UK \\ Bondue, Antoine, Belgium \\ Breuer, Christopher Kane, USA \\ Bulte, Jeff, USA \\ Burdick, Jason A., USA \\ Clevers, Hans, The Netherlands \\ De Luca, Michele, Italy \\ Edinger, Matthias,
Germany \\ Goodship, Allen, UK \\ Grüll, Holger, The Netherlands \\ Guest, Debbie, UK \\ Gulino, Alberto, Italy \\ Hengstler, Jan G., Germany \\ Hescheler, Jürgen, Germany \\ Horwitz, Edwin M., USA \\ Kasashima, Yoshinori, Japan \\ Krause, Karl-Heinz, Switzerland \\ Klemm, Dieter, Germany \\ Kriegstein, Arnold, USA \\ Lendlein, Andreas,
Germany \\ Martin, Ivan, Switzerland \\ Mason, Chris, UK \\ Nagy, Andras,
Canada \\ Niklason, Laura E., USA \\ Nobert, Karl, USA \\ Powers, Linda,
USA \\ Rankin, Sara, UK \\ Razvi, Enal, UK \\ Sawitzki, Birgit, Germany \\ Schultze, Joachim L., Germany \\ Siegel, Bernard, USA \\ Smith, Roger, UK \\ Steinhoff, Gustav, Germany \\ Steinkasserer, Alexander, Germany \\ Tanaka,
Elly M., Germany \\ Torres, Art, USA \\ van Weeren, René, The Netherlands \\ Vidal, Martin, USA \\ Voss, Thorsten, Germany \\ Walles, Heike, Germany \\ Widschwendter, Martin, UK \\ Zhang, Kun, USA
08 World Conference on Regenerative Medicine, November 2–4, 2011
Floor -1
overview ConferenCe venue
counter, check-in
wardrobe
entrance escalators
lift
stairs
relaxingarea
Floor 0
escalators
lift
stairs
poster exhibition area
www.wcrm-leipzig.com \\ 09
information
Floor +1
Floor +2
room10
9
6
7
8
15
14
13
spea
kers
pre
viewroom
11
lift
internet station
stairs
hall 1
hall 2 hall 3
hall 4 hall 5
escalators
lift
stairs
industrial exhibition area
cateringcatering
10 World Conference on Regenerative Medicine, November 2–4, 2011
Hall 2 Hall 3 Hall 4 Hall 5 Room 11
Wednesday, Nov 2, 2011
11:00 am–12:30 pm Signalling & Cancer Vascular Engineering IVRMS I
12:30–02:00 pm Lunch Break
02:00–03:30 pm Adult Stem Cell Sources Cardiac Engineering PhD Session I
03:30–04:00 pm Coffee Break
04:00–05:30 pm Bone & Cartilage Engineering I In Vitro Models In Vivo Models
05:30 pm Opening Ceremony (Hall 1) and Get-together (Exhibition Area)
Thursday, Nov 3, 2011
09:00–10:30 am Bone & Cartilage Engineering II
Surfaces & Cell-Material Interaction
Biomarker Allogenic Cell Therapy
10:30–11:00 am Coffee Break
11:00 am–12:30 pm Bioreactor Technology Scaffolds Commercialization Strategies I
Advances in Measure-ment and Imaging for Regenerative Medicine
Open Access – The Future of Scientific Publishing
12:30–02:00 pm Lunch Break
02:00–03:30 pm Stem Cells and Regeneration of Neuronal Disordes
Biomaterials & Scaffolds Regulatory, Legal & Ethical Issues I
PhD Session II Attune® Acoustic focusing cytometer – Precision & Sensitivity at All Speeds for Rare Event Detection and Precious Samples
03:30–04:00 pm Coffee Break
04:00–05:30 pm Skin & Soft Tissue Regeneration
Biomedical Materials & Implants
Immunological As-pects of Regeneration
Regulatory Affairs
05:30 pm Poster Party (Poster Exhibition Area Floor 0)
Friday, Nov 4, 2011
09:00–10:30 am Cell Therapy Liver, Lung & Kidney Regeneration
Toxicity & Safety Anti-Inflammation & Tissue Regeneration
PhD Session III
10:30–11:00 am Coffee Break
11:00 am–12:30 pm Reprogramming, Epi genomics & Cell Fate
Stem Cell Differentiation Hematopoietic Cell Therapy
Manufacturing Cell Products
12:30–02:00 pm Lunch Break
02:00–03:30 pm Induced Pluripotent Stem Cells
Nerve & Spinal Cord Regeneration
Regulatory, Legal & Ethical Issues II
Cell Tracking & Imaging
03:30–04:00 pm Coffee Break
04:00–05:30 pm Embryonic Stem Cells Bone & Cartilage Engineering III
Commercialization Strategies II
IVRMS II
06:30 pm Social Evening: Tropical Experience World Gondwanaland
Program at a glanCe
www.wcrm-leipzig.com \\ 11
Program
Hall 2 Hall 3 Hall 4 Hall 5 Room 11
Wednesday, Nov 2, 2011
11:00 am–12:30 pm Signalling & Cancer Vascular Engineering IVRMS I
12:30–02:00 pm Lunch Break
02:00–03:30 pm Adult Stem Cell Sources Cardiac Engineering PhD Session I
03:30–04:00 pm Coffee Break
04:00–05:30 pm Bone & Cartilage Engineering I In Vitro Models In Vivo Models
05:30 pm Opening Ceremony (Hall 1) and Get-together (Exhibition Area)
Thursday, Nov 3, 2011
09:00–10:30 am Bone & Cartilage Engineering II
Surfaces & Cell-Material Interaction
Biomarker Allogenic Cell Therapy
10:30–11:00 am Coffee Break
11:00 am–12:30 pm Bioreactor Technology Scaffolds Commercialization Strategies I
Advances in Measure-ment and Imaging for Regenerative Medicine
Open Access – The Future of Scientific Publishing
12:30–02:00 pm Lunch Break
02:00–03:30 pm Stem Cells and Regeneration of Neuronal Disordes
Biomaterials & Scaffolds Regulatory, Legal & Ethical Issues I
PhD Session II Attune® Acoustic focusing cytometer – Precision & Sensitivity at All Speeds for Rare Event Detection and Precious Samples
03:30–04:00 pm Coffee Break
04:00–05:30 pm Skin & Soft Tissue Regeneration
Biomedical Materials & Implants
Immunological As-pects of Regeneration
Regulatory Affairs
05:30 pm Poster Party (Poster Exhibition Area Floor 0)
Friday, Nov 4, 2011
09:00–10:30 am Cell Therapy Liver, Lung & Kidney Regeneration
Toxicity & Safety Anti-Inflammation & Tissue Regeneration
PhD Session III
10:30–11:00 am Coffee Break
11:00 am–12:30 pm Reprogramming, Epi genomics & Cell Fate
Stem Cell Differentiation Hematopoietic Cell Therapy
Manufacturing Cell Products
12:30–02:00 pm Lunch Break
02:00–03:30 pm Induced Pluripotent Stem Cells
Nerve & Spinal Cord Regeneration
Regulatory, Legal & Ethical Issues II
Cell Tracking & Imaging
03:30–04:00 pm Coffee Break
04:00–05:30 pm Embryonic Stem Cells Bone & Cartilage Engineering III
Commercialization Strategies II
IVRMS II
06:30 pm Social Evening: Tropical Experience World Gondwanaland
12 World Conference on Regenerative Medicine, November 2–4, 2011
\\
Hall 3 Hall 4 Hall 5
11:00 am–12:30 pm
Signalling & Cancer
* Clevers HC
* Gulino A
Vascular Engineering
* Breuer CKIVRMS I
* Goodship A
* Rankin S
* Nobert K
* van Weeren R
12:30–02:00 pm
Lunch Break
02:00–03:30 pm
Adult Stem Cell Sources Cardiac Engineering
* Steinhoff GPhD Session I
03:30–04:00 pm
Coffee Break
04:00–05:30 pm
Bone & Cartilage Engineering I
* Blunn G
In Vitro Models In Vivo Models
* Tanaka EM
05:30 pm Opening Ceremony (Hall 1) and Get-together (Exhibition Area)
* Keynote speaker
Program overview
WeDneSDAy, november 2, 2011
www.wcrm-leipzig.com \\ 13
WeDneSDAy, november 2, 2011
Program
Program in detail
11:00 am–12:30 pm
Signalling & Cancer ► Hall 3
Chairs: Aust G, Clevers HC
Lgr5 stem cells in self-renewal and cancer
* Keynote: Clevers HC
Neural stem cells control by the morphogen Hedgehog
* Keynote: Gulino A
Synergistic effect of lenalidomide and dendritic cell vaccination on cancer
immunotherapy
Lee JJ
Autologous dendritic cells pulsed with recombinant human fusion protein
[mucin 1-glutathione S-transferase] coupled to oxidized polymannose as mainte-
nence treatment of epithelial ovarian cancer in remission: A clinical trial update
Lehman M, Prima BioMed Ltd.
Vascular Engineering ► Hall 4
Chairs: Dhein S, Breuer CK
Tissue engineered vascular grafts: From the bench to the bedside and back again
* Keynote: Breuer CK
Additive manufacturing of an artificial blood vessel system by the combination
of inkjet-printing and two-photon polymerization
Engelhardt S
Detergent-based decellularization procedure reduces but not eliminates cellular
proteins in equine carotide arteries: Implications for immunogenicity
Böer U
14 World Conference on Regenerative Medicine, November 2–4, 2011
Co-culture spheroids as a tool for angiogenic research
Metzger W
Electrospun biodegradable materials for vascular regenerative medicine
Damiano G
IVRMS I ► Hall 5
Chairs: Brehm W, Ribitsch I
organized by the International Veterinary Regenerative Medicine Society
Veterinary regenerative medicine – Past, present and future clinical applications
* Keynote: Goodship A
Endogenous release of stem cells
* Keynote: Rankin S
Regulatory affairs for stem cell use in veterinary medicine
* Keynote: Nobert K
The potential of (hybrid) scaffolds for the treatment of orthopaedic disease
* Keynote: van Weeren R
12:30–02:00 pm Lunch Break
www.wcrm-leipzig.com \\ 15
WeDneSDAy, november 2, 2011
Program
02:00–03:30 pm
Adult Stem Cell Sources ► Hall 3
Chair: Metzger M
Transplantation of a newly developed human fetal endothelial cells accelerate
functional recovery in an experimental stroke model
Lee MC
Lineage tracing of adult stem cells in murine heart
Uchida S
Extracting stem cells and surrounding chaperon cells from the zone of Ranvier
out of non-decalcified rabbit knee
Richter H, ROWIAK GmbH
Age-dependent characterization of fibroblasts isolated from human anterior
cruciate ligament
Prager P
Immune modulatory properties of equine umbilical cord blood, bone marrow
and adipose tissue-derived MSCs in vitro
Koch T
Transplantation of human adult enteric neural progenitors into mouse colon
after experimental ablation of the enteric plexus in vivo
Hetz S
Cardiac Engineering ► Hall 4
Chairs: Dhein S, Steinhoff G
Update on cardiac stem cell therapy
* Keynote: Steinhoff G
C-kit+ subpopulations display different proliferation potential and occurrence
in heart of young and aged mice
Mark P
16 World Conference on Regenerative Medicine, November 2–4, 2011
Prospects on the use of stem cells obtained from peripheral blood in
degenerative myocardial pathologies
Cagni G
Matrigel could recruit stem cells for cardiac regeneration
Li W
Bioengineering of the embryonic cardiovascular progenitor cell niche
Schenke-Layland K
PhD Session I ► Hall 5
Chair: Hescheler J
Isolation and maintenance of human adipose stem cells avoiding animal-origin
reagents
Escobedo-Lucea C
VSEL cells are not pluripotent but contain mesenchymal precursors
Heider A
Economic, defined and xeno-free large-scale cryopreservation of HESC with
vegetal hydrolysates for clinical applications
T‘Joen V
Development of embryonic stem cell derived neuronal networks for the
microelectrode array based analysis of network activity
te Kamp V
Micro RNAs influence the generation of induced plurpotent stem cells and
subsequent differentiation into the pancreatic lineage
Jung M
Investigation of pathogenesis of Parkinson´s disease by PD patients derived-
induced pluripotent stem cells
Liao MC
03:30–04:00 pm Coffee Break
www.wcrm-leipzig.com \\ 17
WeDneSDAy, november 2, 2011
Program
04:00–05:30 pm
Bone & Cartilage Engineering I ► Hall 3
Chairs: Schulz R, Blunn G
The interface between regeneration, reconstruction and replacement for bone
and joints
* Keynote: Blunn G
Stem cell based repair of a focal cartilage defect in an ovine model – Longterm
results of a double-blinded randomized trial
Marquass B
Articular cartilage repair using collagen type I hydrogels
Nöth U
The use of poly(L-lactide-co-caprolactone) as a scaffold for adipose stem cells in
bone tissue engineering: Application in a spinal fusion model
Vergroesen PP
In Vitro Models ► Hall 4
Chair: Peters M
Hypoxia changes main characteristics of human bone marrow-derived
mesenchymal stromal cells in vitro
Wobus M
Drug discovery for neurological disorders: A novel 3D in vitro Alzheimer´s
disease model
Krinke D
Every cell counts – Quantification of the reepithelialization process in human
wound healing
Westphal K; Safferling K
Human hair follicle equivalents in vitro for transplantation and substance testing
Ataç B
18 World Conference on Regenerative Medicine, November 2–4, 2011
3D spheroids of adipose-derived stem cells as building blocks for adipose tissue
regeneration
Blunk T
Loss of Dnd1 facilitates the cultivation of genital ridge-derived rat embryonic
germ cells
Zschemisch NH
In Vivo Models ► Hall 5
Chairs: Tanaka EM, Wagner DC
Multilineage regeneration in the amphibian limbs: A tale of different tissues
* Keynote: Tanaka EM
Inflammatory response and apoptotic cell death in injured zebrafish spinal cord
Hui SP
Large animal model (swine) for cell-based cardiovascular repair in acute
myocardial infarction: One year follow up
Crovace A
Inner ear rehabilitation in the deafened cochlea of NOD-SCID mice following
transplantation of human pluripotent mesenchymal stem cells
Revoltella RP
Sweat gland-derived stem cells improve vascularization in scaffold-based
dermal regeneration
Danner S
www.wcrm-leipzig.com \\ 19
WeDneSDAy, november 2, 2011
Program
05:30 pm
Opening Ceremony ► Hall 1
Welcome adresses
\\ Dr. Helge Braun, MdB
(Parliamentary State Secretary, Federal Ministry of Education and Research)
\\ Prof. Dr. Dr. Sabine von Schorlemer
(State Minister, Saxon State Ministry for Science and the Arts)
\\ Uwe Albrecht
(Deputy Mayor for Economic Affairs and Employment, City of Leipzig)
\\ Prof. Dr. Beate A. Schücking
(Rector of the Universität Leipzig)
\\ Prof. Dr. Frank Emmrich
(Conference President, Director Fraunhofer Institute for Cell Therapy and Immunology
and Translational Centre for Regenerative Medicine Leipzig)
Musical interlude “Neue Musik Leipzig“ (New Music Leipzig)
Overview of the California Institute for Regenerative Medicine (CIRM)
Senator Art Torres, (Ret.) (Vice-Chair of the Governing Board of the CIRM)
07:00 pm
Get-together ► Exhibition Area
20 World Conference on Regenerative Medicine, November 2–4, 2011
\\ Program overview
thurSDAy, november 3, 2011
Hall 2 Hall 3 Hall 4 Hall 5 Room 11
09:00–10:30 am
Bone & Cartilage Engineer-ing II
Surfaces & Cell-Material Interaction
* Burdick JA
Biomarker
* Schultze JL
* Widschwend- ter M
* Grüll H
* Voss T
Allogenic Cell Therapy
10:30–11:00 am
Coffee Break
11:00 am–12:30 pm
Bioreactor Technology
* Walles H
Scaffolds Commercializa-tion Strategies I
* Powers L
* Razvi E
Advances in Measurement and Imaging for Regenera-tive Medicine
Open Access – The Future of Scientific Publishing
12:30–02:00 pm
Lunch Break
02:00–03:30 pm
Stem Cells and Rege-neration of Neuronal Disordes
* Krause KH
Biomate-rials & Scaffolds
* Lendlein A
Regulatory, Legal & Ethical Issues I
PhD Session II Attune® Acoustic Focusing Cytome-ter – Precision & Sensitivity at All Speeds for Rare Event Detection and Precious Samples
03:30–04:00 pm
Coffee Break
04:00–05:30 pm
Skin & Soft Tissue Rege-neration
* De Luca M
Biomedical Materials & Implants
* Klemm D
Immunological Aspects of Regeneration
* Steinkasserer A
* Sawitzki B
Regulatory Affairs
05:30 pm Poster Party (Poster Exhibition Area Floor 0)
* Keynote speaker
www.wcrm-leipzig.com \\ 21
Program
thurSDAy, november 3, 2011
Program in detail
09:00–10:30 am
Bone & Cartilage Engineering II ► Hall 2
Chair: Meisel HJ
Keeping up the pace of bone regeneration: What can we learn by comparing
giants with miniatures?
Tryfonidou M
Mechanostimulation reverses the catabolic phenotype of human osteoarthritic
matrix-embedded chondrocyts – A preliminary report
Halbwirth F
Optimization of tissue engineering constructs using jaw periosteal cells
Alexander D
3D multilayered co-culture system for investigating chondrogenesis in
mesenchymal stem cells
Millan C
Simplet (smp) is required for regeneration and beta-catenin-dependent Wnt
signal transduction
Antos C
Effect of sinusoidal loading frequencies on calcification of tissue-engineered
bone in vitro
Koaykul C
Surfaces & Cell-Material Interaction ► Hall 3
Chair: Francke M
Engineering biomaterial design to control stem cell interactions
* Keynote: Burdick JA
Cell morphometric analysis of osteoblasts on geometrically microstructured
titanium surfaces – Basic research for orthopedic implants
Matschegewski C
22 World Conference on Regenerative Medicine, November 2–4, 2011
Modulation of inflammatory macrophage functions by artificial extracellular
matrices used as biomaterial coatings
Franz S
The enhanced modulation of key bone matrix components by modified
titanium implant surfaces
Brett P
Electrospun collagen II and (poly-epsilon-caprolactone) co-polymer nanofibres
– Biomimetic scaffold design with chondro-inductive properties
Rackwitz L
Biomarker ► Hall 4
Chair: Schultze JL
Adaptive learning and simulation approaches enhance molecular diagnostics of
malignant and infectious diseases
* Keynote: Schultze JL
Epigenetics, stem cells and cancer
* Keynote: Widschwendter M
See, reach, treat: Biomarkers and imaging for diagnosis and treatment of
diseases
* Keynote: Grüll H
The better the source, the more to explore
* Keynote: Voss T
www.wcrm-leipzig.com \\ 23
Program
thurSDAy, november 3, 2011
Allogenic Cell Therapy ► Hall 5
Chair: Horwitz EM, President of ISCT and Chairman of Pluristem‘s Scientific Advisory Board
organized by Pluristem Therapeutics Inc.
Placental-derived adherent cells for the treatment of peripheral vascular
disease: FDA / EMA-approved phase I / IIa clinical trial
* Keynote: Horwitz EM
PLX cells for the treatment of irradiation exposure
* Keynote: Gorodetsky R
The biology of mesenchymal-like adherent stromal cells, cultured in 3D
scaffolds
Speaker: Abraham E
10:30–11:00 am Coffee Break
11:00 am–12:30 pm
Bioreactor Technology ► Hall 2
Chairs: Christ B, Walles H
Bioreactor technology and automatization in the production of human 3D
tissues
* Keynote: Walles H
Mass expansion of human pluripotent stem cells (hPSC) in controlled, stirred
bioreactors
Zweigerdt R
Development of a bioreactor for the in vitro culture of bone tissue supported
by computer fluid simulations
Kahlig A
24 World Conference on Regenerative Medicine, November 2–4, 2011
A novel animal component free surface for growth of stem cells and other
fastidious cells
Marwood T, Thermo Fisher Scientific
Osteogenic differentiation of mesenchymal stem cells under controlled and
reproducible conditions in two parallel perfusion bioreactors
Kress S
Scaffolds ► Hall 3
Chair: Simon J
organized by Transregio TRR 67
Introduction to the Transregio matrix engineering
Simon J
Artificial extracellular matrix composed of collagen I and sulphated glycosami-
noglycans induces a proliferative dermal fibroblast phenotype in vitro
van der Smissen A
Investigation of the interaction of interleukin-8 with hyaluronan, chondroitin
sulfate, dermatan sulfate, and their sulfated derivatives by fluorescence and
solution NMR spectroscopy and molecular modelling
Pichert A
Artificial extracellular matrices composed of collagen I and synthetic GAG
derivatives promote osteogenic differentiation of human mesenchymal stromal
cells
Hempel U
Enhancing osseointegration with addition of glycosaminoglycans to titanium
surfaces
Rammelt S
www.wcrm-leipzig.com \\ 25
Program
thurSDAy, november 3, 2011
Commercialization Strategies I ► Hall 4
Chair: Faber S
Stem cell products in development: Where is progress being made?
* Keynote: Powers L
Stem cells worldwide market snapshot
* Keynote: Razvi E
Advances in Measurement and Imaging for Regenerative Medicine ► Hall 5
Chair: Macdonald R
organized by PTB (national metrology institute)
Analysis of cell-surface interactions using 3D cell morphometry
Shaw M
Multi-parametric monitoring of cell quality in regenerative medicine products
Baradez MO
Assessment of measurement of cell confluency level by image analysis
Kummrow A
Chemical selective in vitro bio-assay for cells / EC matrix detection in 3D not-
labelled cell cultures
Sassi MP
Quantitative assessment of cell viability based on flow cytometry and microscopy
Frankowski M
26 World Conference on Regenerative Medicine, November 2–4, 2011
Open Access – The Future of Scientific Publishing ► Room 11
organized by InTech – Open Access Publisher
Advantage of Open Access publishing in medicine
Rylett N
Author‘s perspective
t.b.a.
Round table discussion about Open Access in medicine
Bajic B
12:30–02:00 pm Lunch Break
02:00–03:30 pm
Stem Cells and Regeneration of Neuronal Disordes ► Hall 2
Chairs: Krause KH, Peters M
Pluripotent stem cell-based therapy of Parkinson‘s disease
* Keynote: Krause KH
The grafted fetal neural progenitor cells can integrate in the adult hippocampal
tissue after ischemic injury
Butenko G
Direct conversion of fibroblast cells into tripotent neural stem cells
Edenhofer F
Cellular “functional replacement” with a “cell-free strategy” in early
Alzheimer‘s and Parkinson‘s diseases: Evidences from related animal models
Fernandez CI
www.wcrm-leipzig.com \\ 27
Program
thurSDAy, november 3, 2011
Biomaterials & Scaffolds ► Hall 3
Chairs: Jäger R, Lendlein A
Multifunctional biomaterials
* Keynote: Lendlein A
Scaffold mediated non-viral inhibition of collagen type I and type III in cardiac
fibroblasts
Monaghan M
Fabrication of scaffolds via two-photon polymerization and microreplication
techniques
Koroleva A
Cell behaviour on resorbable nonwovens composed of biodegradable
polyglycolic or polylactide acid for the cardiovascular tissue engineering
Lüders C
Regulatory, Legal & Ethical Issues I ► Hall 4
Chair: Siegel B
Pre-clinical efficacy and safety requirements for the approval of cell-based
medicinal products – Demonstration of the efficacy and safety testing concept
at Fraunhofer IZI and TRM Leipzig
Lehmann J, Schulz R
Stem cell research and banking: International perspectives
Isasi R
The search for new stem cell research rules between the poles of the recent
preimplantation genetic diagnosis sentence of the federal supreme court and
the impact of reprogrammed stem cells in Germany
Faltus T
28 World Conference on Regenerative Medicine, November 2–4, 2011
Preparing the grounds: Setting standards to shape the business environment
for tommorrw´s market success of your innovative products for application in
regenerative medicine
Wenzelewski K
Medicinal feasibility “in bench to bedside projects“
Meisel HJ
PhD Session II ► Hall 5
Chair: Walles H
Infrapatellar fat pad as an alternative source of mesenchymal stem cells: New
strategies for cartilage tissue engineering
Lopa S
Improvement of cardiac function and restoration of beta-adrenergic
responsiveness in dilative cardiomyopathy by implantation of a novel cardiac
assist device (Engineered Heart Tissue) in a rat model
Schlegel F
Fabrication of tissue engineered fibrin based aortic heart valves with sinuses of
valsalva
Borgmann A
Revascularisation of skin grafts – Vascular transformations and proteolytic
activity
Knapik A
Mesenchymal stromal cells immobilized in an oriented 3D scaffold transiently
accelerate functional recovery after acute spinal cord injury
Montzka K
www.wcrm-leipzig.com \\ 29
Program
thurSDAy, november 3, 2011
Attune® Acoustic Focusing Cytometer – Precision & Sensitivity
at All Speeds for Rare Event Detection and Precious Samples ► Room 11
organized by Life Technologies GmbH
Attune® acoustic focusing cytometer – Precision & sensitivity at all speeds for
rare event detection and precious samples
Thompson R
03:30–04:00 pm Coffee Break
04:00–05:30 pm
Skin & Soft Tissue Regeneration ► Hall 2
Chairs: De Luca M, Magin T
Limbal stem-cell therapy and long-term corneal regeneration
* Keynote: De Luca M
Outer root sheath melanocytes as a causal autologous therapy for vitiligo
Savkovic V
Update on ATMPs in veterinary medicine: From lab to patient´s site
Emmendörffer A, V-Care Biomedical GmbH
Cell minig offers a new autologous stem cell source residing in sweat glands for
skin regeneration of burns
Salem H
Target tissue-specific scaffold design for rotator cuff repair – The isotropy of
collagen I nanofibre scaffolds regulate the behaviour and tenogenic differentia-
tion of mesenchymal stem cells
Rackwitz L
30 World Conference on Regenerative Medicine, November 2–4, 2011
Biomedical Materials & Implants ► Hall 3
Chairs: Klemm D, Mayr S
Nanocelluloses: Natural, biomimetic, and bioactive materials for applications as
patches and even as heart bypass
* Keynote: Klemm D, Jenpolymers Ltd.
Additive manufacturing of an artificial blood vessel system: Optimum lay-out
and fluid-mechanical characterization
Jäger R
Controlled biodegradation of PCL electrospun nanofiber-based scaffolds
Kim GM
Cell seeding of collagen scaffolds via cell printing
Glasmacher B
Modulation of hydrogel degradation guides endothelial cell morphogenesis
Chwalek K
Immunological Aspects of Regeneration ► Hall 4
Chairs: Sack U, Sawitzki B
Soluble CD83 modulates autoimmunity and promotes tolerance induction to
transplants
* Keynote: Steinkasserer A
How to target memory T cells and restore tolerance?
* Keynote: Sawitzki B
Extracorporeal cell-therapy of patients with septic shock using human donor
granulocytes
Mitzner S
Impact of engineered extracellular matrices on the immunomodulatory proper-
ties of mesenchymal stromal cells
Wehner R
www.wcrm-leipzig.com \\ 31
Program
thurSDAy, november 3, 2011
Regulatory Affairs ► Hall 5
Chair: Mazouz C, VP Clinical & Regulatory Affairs
organized by Pluristem Therapeutics Inc.
Transition from pre-clinical to clinical development; the devil is in the details
* Keynote: Bravery CA
Allogeneic cellular product candidate; case study “off the shelf” PLX cells
Speaker: Mazouz C
t.b.a.
Speaker: Balshüsemann D
t.b.a.
Speaker: Guenther C
05:30 pm
Poster Party ► Poster Exhibition Area
Discussion of the posters. Drinks and finger food will be served.
07:00 pm: Award ceremony for best abstract and best poster
Best Abstract and Best Poster Award kindly supported by Pluristem Therapeutics Inc.
32 World Conference on Regenerative Medicine, November 2–4, 2011
\\ Program overview
friDAy, november 4, 2011
Hall 2 Hall 3 Hall 4 Hall 5 Room 11
09:00–10:30 am
Cell Therapy
* Edinger MLiver, Lung & Kidney Regeneration
* Niklason LE
Toxicity & Safety
* Hengstler JG
Anti-Inflam-mation & Tissue Regeneration
PhD Session III
10:30–11:00 am
Coffee Break
11:00 am–12:30 pm
Reprogram-ming, Epi-genomics & Cell Fate
* Zhang K
Stem Cell Differentiation
* Bondue A
Hematopoietic Cell Therapy
* Horwitz EM
Manufacturing Cell Products
* Martin I
12:30–02:00 pm
Lunch Break
02:00–03:30 pm
Induced Pluri-potent Stem Cells
* Nagy A
Nerve & Spinal Cord Regene-ration
* Kriegstein A
Regulatory, Legal & Ethical Issues II
* Siegel B
Cell Tracking & Imaging
* Bulte J
* Kasashima Y
03:30–04:00 pm
Coffee Break
04:00–05:30 pm
Embryonic Stem Cells
* Hescheler J
* Guest D
Bone & Carti-lage Engineer-ing III
Commerciali-zation Strategies II
* Allsopp T
* Mason C
IVRMS II
* Smith R
* Vidal M
* Nixon AJ
06:30 pm Social Evening: Tropical Experience World Gondwanaland
* Keynote speaker
www.wcrm-leipzig.com \\ 33
Program
friDAy, november 4, 2011
Program in detail
09:00–10:30 am
Cell Therapy ► Hall 2
Chairs: Alt R, Edinger M
CD4+CD25+ regulatory T cells in allogeneic stem cell transplantation
* Keynote: Edinger M
Combining gene and cell therapy for stimulation of vascularisation in ischemic
skeletal muscle
Makarevich P
Local cytokine profile after autologous transplantation of muscle derived cells
into the skeletal muscle
Burdzinska A
Intra-articular administration of autologous platelet rich plasma for lameness
associated with fetlock arthritis: A case series
Mirza M
Liver, Lung & Kidney Regeneration ► Hall 3
Chairs: Christ B, Niklason LE
Lung regeneration: Progress and challenges
* Keynote: Niklason LE
Novel growth factor containing hydrogels to support tubular regeneration
after acute kidney injury
Tsurkan M
Characterization of decellularized lung tissue using vascular corrosion casting
Ouyang Y
34 World Conference on Regenerative Medicine, November 2–4, 2011
Human kidney-derived cells cultured on small intestinal submucosa to generate
a renal proximal tubule model
Hoppensack A
Self-renewal factor Bmi1 is involved in adult hepatic progenitor cell prolifera-
tion and differentiation
Penning L
Toxicity & Safety ► Hall 4
Chairs: Hengstler JG, Lehman J
Cell alignment along micro-vessels as order principle to regenerate tissue
architecture: From experiment to virtual tissues and back
* Keynote: Hengstler JG
Neural cell transplantation in patients with neurodegenerative disorders:
In vitro validation and safety assessment
Moellers S
Evaluation of human MMSCs susceptibility to SiO2-based nanoparticles
Andreeva E
A new device for screening hepatotoxicity: Test results with the muscle
relaxant Rocuronium
Sauer M
www.wcrm-leipzig.com \\ 35
Program
friDAy, november 4, 2011
Anti-Inflammation & Tissue Regeneration ► Hall 5
Chair: Reinecke J
organized by ORTHOGEN Lab Services GmbH and ORTHOGEN Veterinary GmbH
Interest in regenerative medicine resurges. Where does it put PRP and ACS?
Reinecke J, Orthogen
Intralesional treatment of equine tendon lesions with platelet rich plasma (PRP)
and autologous conditioned serum (ACS)
Geburek F
Clinical and experimental evidence for tissue regeneration through autologous
conditioned serum
Moser C
PhD Session III ► Room 11
Chair: Mason C
Antigen processing is impaired in mouse pluripotent stem cell lines
Monecke S
Reconstruction of tracheal lessions by bioartificial tissue – From R&D to GMP
Dally I
Detection of collagen produced by live human corneal fibroblasts and human
mesenchymal stem cells cultured in 3D fibrin gel using label free non-invasive
imaging
Mortati L
Dermal fibroblasts display similar phenotypic and differentiation capacity to
fat-derived mesenchymal stem cells, but differ in anti-inflammatory and
angiogenic potential
Blasi A
36 World Conference on Regenerative Medicine, November 2–4, 2011
Direct chemosensitivity testing using a novel biosensoric screening system for
the individualized therapy of the malignant melanoma
Pönick S
Topological effects of magnetic nanoparticles embedded in the polymeric
ultra-thin films for cardiac repair on cell adhesion and proliferation properties
Ventrelli L
10:30–11:00 am Coffee Break
11:00 am–12:30 pm
Reprogramming, Epigenomics & Cell Fate ► Hall 2
Chairs: Schröder I, Zhang K
The genomics and epigenomics of nuclear reprogramming
* Keynote: Zhang K
In vitro aging of human IPS derived fibroblasts
Arnold A
HMGA2 links self-renewal and senescence of mesenchymal stem cells via its
interaction with the CDKN2A-locus
Markowski D
Induced pluripotent stem cells for basic research and practical applications
Kiselev S
www.wcrm-leipzig.com \\ 37
Program
friDAy, november 4, 2011
Stem Cell Differentiation ► Hall 3
Chairs: Bondue A, Cross M
Defining MESP1 function during early cardiovascular progenitor specification
* Keynote: Bondue A
In vitro generation of pancreatic islet bodies from mouse embryonic stem cells
using a 3D differentiation model
Hommel A
Development of robust, scalable, and synthetic systems for the maintenance of
pluripotency and subsequent differentiation
McRae S, Cell Guidance Systems Ltd
Mesenchymal stromal cells from the amniochorionic membrane uf human term
placenta: Potential cell sources for knee cartilage tissue engineering
Jaramillo-Ferrada P
Adipose-derived stem cells form functional myotubes from mechanically-
induced differentiation whereas bone marrow-derived stem cells do not
Engler A
Hematopoietic Cell Therapy ► Hall 4
Chairs: Fricke S, Horwitz EM
Homologous and nonhomologous hematopoietic cell therapy: Tales of blood
and bone
* Keynote: Horwitz EM
Regeneration of hematopoiesis by non adherent bone marrow cells (NABMC)
after hematopoietic stem cell transplantation in humanized mice
Hilger N
Specific gene transfer to CD133-positive hematopoietic stem cells
Kneissl S
Substrate elasticity controls hematopoietic stem cell adhesion and migration
Lee-Thedieck C
38 World Conference on Regenerative Medicine, November 2–4, 2011
Manufacturing Cell Products ► Hall 5
Chairs: Martin I, Savkovic V
Challenges for the manufacturing and clinical use of 3D cellular grafts
* Keynote: Martin I
Advances in cellular therapy using the Sepax 2 processing platform
Egermann M, Biosafe S.A.
Synthesis and evaluation of a bispecific antibody construct for targeting
and retention of bone marrow derived multipotent stromal cells in infarcted
myocardium
Gundlach IV CW
Cell culture media: Part of your therapeutic assay, part of your registration
Wiesner A, PAA Laboratories
12:30–02:00 pm Lunch Break
02:00–03:30 pm
Induced Pluripotent Stem Cells ► Hall 2
Chair: Stolzing A
Transposon-mediated reprogramming provides a powerful tool for
understanding stem cell induction
* Keynote: Nagy A
Fibroblast contribution to bioartificial cardiac tissue formation from murine
induced pluripotent stem cells
Gruh I
Treating experimental spinal cord injury with human fetal neural stem cells or
human induced pluripotent stem cell-derived neural precursors
Romanyuk N
www.wcrm-leipzig.com \\ 39
Program
friDAy, november 4, 2011
Induced pluripotent cell-derived neural precursors in the treatment of focal
brain ischaemia in rats
Turnovcova K
Generation of equine induced pluripotent stem cells
Breton A
Nerve & Spinal Cord Regeneration ► Hall 3
Chair: Boltze J
Neural stem and progenitor cells in human cortical development and therapeutics
* Keynote: Kriegstein A
Autologous mesenchymal stem cell therapy for spinal cord injury: Effect of the
level of injury on long term safety and clinical efficacy
Gabr H
A unifying hypothesis of how MultiStem® provide therapeutic benefit in
multiple models of CNS injury and disease
Mays R, Athersys Inc.
Electrospun silk fibers promote oriented axon regeneration of CNS neurons in
vitro
Claudepierre T
Injectable hydrogel-based formulations for spinal cord regeneration
des Rieux A
Regulatory, Legal & Ethical Issues II ► Hall 4
Chair: Faltus T
The mandate to deliver cures: The law and politics relating to stem cell research
and its translation to the clinic
* Keynote: Siegel B
Regulatory complexities in the clinical translation of stem cells: The experience
of the Andalusian Initiative for Advanced Therapies
Cuende N
40 World Conference on Regenerative Medicine, November 2–4, 2011
Application of risk management and requirements for processing practices for
medical products containing viable human cells – A new international standard
Kloth S
What are the “real“ ethical questions in regenerative medicine?
Sethe S
Cell Tracking & Imaging ► Hall 5
Chair: Tarnok A
Cell tracking and regenerative medicine: Clinical needs and technological
solutions
* Keynote: Bulte J
In vivo tracking of implanted bone marrow-derived mesenchymal stem cells
labelled by CM-DiI
* Keynote: Kasashima Y
In vivo tracking of intra-articularly injected SPIO-labelled MSC in a large animal
model of osteoarthritis using magnetic resonance imaging
Delling U
03:30–04:00 pm Coffee Break
www.wcrm-leipzig.com \\ 41
Program
friDAy, november 4, 2011
04:00–05:30 pm
Embryonic Stem Cells ► Hall 2
Chairs: Hescheler J, Schröder I
From basic research to the clinic: Obstacles and options for stem cell therapies
in regenerative medicine with emphasis on pluripotent stem cells
* Keynote: Hescheler J
The potential of embryonic stem cells for clinical use in the horse
* Keynote: Guest D
Nanotopography-induced osteogenic differentiation of human embryonic stem
cells and adult skeletal stem cells
Kingham E
Functionality of human embryonic stem cell-derived neuronal cells in 3D
Ylä-Outinen L
Induction of osteogenic differentiation of murine embryonic stem cells by
confined compressive load and the role of RGD dependent integrins in
mechanotransduction
Hazenbiller O
Bone & Cartilage Engineering III ► Hall 3
Chair: Marquass B
Reduced chondrogenic hypertrophy in vitro following Sox9 gene transfer in
human mesenchymal stem cells
Kunz M
Proliferation potential of the MSCA-1+ subpopulation isolated from
jaw-periosteum
Olbrich M
42 World Conference on Regenerative Medicine, November 2–4, 2011
Direct gene transfer for cartilage repair using coagulated bone marrow aspirate
– Bone morphogenetic protein-2 [BMP2] as potent chondrogenic inductor with
the risk of osteophyte formation in a rabbit model
Sieker J
Gene expression profiling of naturally occurring early intervertebral disc (IVD)
degeneration in dogs
Tryfonidou M
Viability and osteogenic response of pre-osteoblastic cells on poly(N-isopropyl-
acrylamide) functionalized with bone morphogenetic protein-2 (BMP-2)
Chatzinikolaidou M
Commercialization Strategies II ► Hall 4
Chair: Faber S
Regenerative medicine & the biopharmaceutical industry: Partnering & funding
mechanisms
* Keynote: Allsopp T
The cell therapy industry: Past, present & future
* Keynote: Mason C
www.wcrm-leipzig.com \\ 43
Program
friDAy, november 4, 2011
IVRMS II ► Hall 5
Chairs: Brehm W, Smith R
organized by the International Veterinary Regenerative Medicine Society
Effects of stem cell treatment in naturally-occurring tendon and ligament
injuries in horses
* Keynote: Smith R
In vivo tracking of TC-HMPAO labeled mesenchymal stem cells in
experimentally-induced tendon lesions in the equine distal limb
* Keynote: Vidal M
Regenerative approaches to equine tendonitis – Stem cell hierarchy through
disease modelling
* Keynote: Nixon AJ
Biochemical characteristics of the equine autologous conditioned plasma
Ionita JC
06:30 pm
Social Evening: Tropical Experience World Gondwanaland ► Zoo Leipzig
44 World Conference on Regenerative Medicine, November 2–4, 2011
sPeCial: veterinary mediCine Program
In connection with the 2nd International Conference of the IVRMS and the World
Conference on Regenerative Medicine (Leipzig, November 2–4, 2011) the first IVRMS
workshop for veterinary practitioners and clinicians will be offered:
regenerative mediCine in veterinary CliniCal PraCtiCe
LectureS
\\ Blunn G
The interface between regeneration, reconstruction and replacement for
bone and joints
November 2, 2011, 04:00–05:30 pm, Hall 3
\\ Goodship A
Veterinary regenerative medicine – Past, present and future clinical
applications
November 2, 2011, 11:00 am–12:30 pm, Hall 5
\\ Guest D
The potential of embryonic stem cells for clinical use in the horse
November 4, 2011, 04:00–05:30 pm, Hall 2
\\ Ionita JC
Biochemical characteristics of the equine autologous conditioned plasma
November 4, 2011, 04:00–05:30 pm, Hall 5
SPeciAL: veterinAry meDicine
www.wcrm-leipzig.com \\ 45
Program
\\ Kasashima Y
In vivo tracking of implanted bone marrow-derived mesenchymal stem cells
labelled by CM-DiI
November 4, 2011, 02:00–03:30 pm, Hall 5
\\ Koch T
Immune modulatory properties of equine umbilical cord blood, bone
marrow and adipose tissue-derived MSCs in vitro
November 2, 2011, 02:00–03:30 pm, Hall 3
\\ Nixon AJ
Regenerative approaches to equine tendonitis – Stem cell hierarchy through
disease modelling
November 4, 2011, 04:00–05:30 pm, Hall 5
\\ Nobert K
Regulatory affairs for stem cell use in veterinary medicine
November 2, 2011, 11:00 am–12:30 pm, Hall 5
\\ Rankin S
Endogenous release of stem cells
November 2, 2011, 11:00 am–12:30 pm, Hall 5
\\ Smith R
Effects of stem cell treatment in naturally-occurring tendon and ligament
injuries in horses
November 4, 2011, 04:00–05:30 pm, Hall 5
\\ van Weeren R
The potential of (hybrid) scaffolds for the treatment of orthopaedic disease
November 2, 2011, 11:00 am–12:30 pm, Hall 5
\\ Vidal M
In vivo tracking of TC-HMPAO labeled mesenchymal stem cells in
experimentally-induced tendon lesions in the equine distal limb
November 4, 2011, 04:00–05:30 pm, Hall 5
46 World Conference on Regenerative Medicine, November 2–4, 2011
Anzeige
Fraunhofer Life Science Symposium 2012
stem cells and clinical applications
November 29–3
0, 2
012
7th annual congress of the german society for stem cell research
associated with
fraunhofer life science symposium 2012
www.fs-leipzig.com
frAunhofer Life Science SymPoSium
www.wcrm-leipzig.com \\ 47
Program
fraunhofer life sCienCe symPosium
orgAnizAtion
SeSSionS
\\ Surfaces & Cell-Material Interaction
Thursday, November 3, 2011, 11:00 am–12:30 pm, Hall 3
\\ Biomaterials & Scaffolds
Thursday, November 3, 2011, 02:00–03:30 pm, Hall 3
\\ Biomedical Materials & Implants
Thursday, November 3, 2011, 04:00–05:30 pm, Hall 3
Biomaterials and Scaffolds
2011
FraunhoferLife Science SymposiumLeipzig
frAunhofer Life Science SymPoSium
www.wcrm-leipzig.com \\ 49
Program
Select Biosciences Business Tutorial: Stem Cells Worldwide Market Analysis
In Conjunction with the World Conference on Regenerative Medicine (WRM) 2011
17:00-20:00, 3 November 2011, Leipzig, GermanyPresented by Enal Razvi, PhD, Biotechnology Analyst, Select Biosciences Ltd
Scope of this Business TutorialAdult Stem Cells, Cord Blood Stem Cells, hESCs/iPSCs, and Cellular Therapy: Technology Trends,
Market Analysis, and Pipeline of Therapeutics in Development
Topics Presented at this Tutorial
• Primary Market Survey Data from Global Respondent Pools • Types of Adult Stem Cells being Studied Currently in Disease Areas • Current Status of Clinical Trials Utilizing Adult Stem Cells: Breakout by Disease Area, Trial Metrics • Current Status of Approved Cellular Therapeutics • Quantitative Research Trends and Quantitative Market Metrics/Penetrance: Types of Reagents, Culture Media/Supplements, and Vendors Supplying these Research Products • Umbilical Cord Blood Banking Market Analysis: Size, Growth Rate, Market Segmentation, Global Distribution, Public vs. Private Cord Blood Banking • Market Analysis of Current Research Trends in hESCs and iPSCs
Who Should Attend
• Scientists in Academia, Biotechnology and Pharmaceutical and Companies • Business Development, Licensing, and Marketing Executives in Pharmaceutical and Biotechnology companies • Representatives from Academic Institutions (Licensing and Technology Transfer) • Established and Start-up Companies Currently in or Contemplating Entry into the Stem Cells Marketplace • The Investment Community
Registration and more information at the registration desk.
Total Price: €795
www.wcrm-leipzig.com \\ 51
Poster Presentation
\\ overview Poster exhibition
fLoor 0
PoSter cAtegorieS
■ Stem Cells
■ Cell- & Tissue Engineering
■ Cell Therapy
■ Models
■ Molecular Mechanisms & Biomarker
■ Immunological Aspects
■ Biomaterials & Scaffolds
■ Regulatory
escalators
lift
stairs
001–008 165–172
173–204245–276205–244
009–062
111–164
063–086 087–110
52 World Conference on Regenerative Medicine, November 2–4, 2011
Posters
■ PP001 Phenotypic characterisation of lin-CD45- VSEL cells in hUCBAlt R
■ PP002 Recent findings on the effects of adult stem cells in the treatment of heart failure patients (A clinical studies review)Arti A
■ PP003 Recent findings on the effects of adult stem cells in the treatment of cardiomyopathy patients (A clinical studies review) Arti A
■ PP004 New findings on the application of adult stem cells in the treatment of cardiomyo-pathy (A preclinical studies review)Arti A
■ PP005 New findings on the application of adult stem cells in the treatment of heart failure (A preclinical studies review)Arti A
■ PP006 Epithelial differentiation potential of adipose-derived stem cellsBaer P
■ PP008 Colonization of collagen scaffolds by adipocytes derived from mesenchymal stem cells of the common marmoset monkeyMueller T
■ PP009 Establishing selection criteria for enrichment, preservation and recovery of optimum quantity of hematopoietic stem cells from umbilical cord blood: A study to improve efficiency in cord blood stem cell bankingBiswas A
■ PP010 Characterization of osteoprogenitors functionally isolated from human mesenchymal stem cells by a runx2 reporter adenovirus Bruderer M
■ PP011 Stem cell self-renewal: Lessons from benign tumorsBullerdiek J
■ PP012 Quantitative x-ray microanalytical evaluation of endothelial and endothelial-like cells for vascular tissue engineeringCampos A
■ PP013 Isolation, maintenance and characterization of multipotent mesenchymal stem cells from canine umbilical cord matrixCha SH
■ PP014 Growth features and cellular crosstalk in human gliomaChoschzick I
■ PP015 Production of GABAergic neurons differentiated from BMSCs-derived -neurosphere cellsDarabi S
■ PP017 Regeneration of the intervertebral disc (nucleus pulposus) using in vitro differen-tiated human mesenchymal stem cellsEhlicke F
■ PP018 Human tissue-culture adapted hepatocytes for cell therapy, drug testing and cancer researchFekete N
■ PP019 Hypoxia induces embryonic stem cell-specific micro RNA cluster 302 and pluripotency-associated genes in human mesenchymal stroma cellsFoja S
www.wcrm-leipzig.com \\ 53
Poster Presentation
■ PP020 Comparision of cell populations from salivary glands obtained by different preparaton proceduresFrahm S
■ PP022 Characterization of neural differentiation of embryonic stem cells by marker expression analysisFronz U
■ PP023 Efficiency of adipogenic differentiation methods in mesenchymal stromal cells from diverse sourcesGittel C
■ PP024 Isolation of mesenchymal stromal cells from solid tissues: Cell features after digestion versus migrationGittel C
■ PP025 Expression pattern of stem cell specific markers and micro RNAs during rabbit embryonic development and in embryonic stem cellsGocza E
■ PP026 A new method to culture neural stem cells of the myenteric plexus from adult mouse by maintaining the stem cell niche in vitro Grundmann D
■ PP027 The effects of hypoxia on cultured human corneal epithelial stem cellsHenein C
■ PP028 The human appendix, a potential neural stem cell sourceHeumüller S
■ PP029 Comparison of human embryonic SA002 stem cell culture techniques concerning to their differentiation potential in vitro and in vivoKeil M
■ PP030 Generation of hematopoietic lineage cells from human adeno-iPS cells Khamisipour G
■ PP031 Multipotent stromal cells derived from human embryonic stem cells exhibit functional characteristics of perivascular progenitor cellsKim JM
■ PP032 Dynamics of neuronal development in the adult hippocampusKirste I
■ PP033 TGF-ß and bovine serum albumin are major factors influencing human embryonic stem cell proliferation Knöspel F
■ PP034 Neural differentiation of adipose-derived mesenchymal stem cells on IKVAV-modified superporous hydrogel scaffoldsKubinova S
■ PP035 Cultivation of cells with stem potential from nail matrixKyryk V
■ PP036 Human embryonic stem cells as a model system and a source of cells for regenerative medicineLagarkova M
■ PP037 GMP-conform expansion of umbilical cord derived mesenchymal stem cellsLavrentieva A
■ PP038 Effect of human embryonic stem cell-derived neuronal precursor cell transplantation into the cerebral infarct model of rat with exerciseLee SU
■ PP039 A novel cardioprotective mechanism mediated by bone marrow c-kit+ERalpha+ cell via paracrine IL-6Li J
54 World Conference on Regenerative Medicine, November 2–4, 2011
■ PP041 Low serum culture conditions for the expansion of human mesenchymal stromal cells eliminates the need for serum testingMontzka K
■ PP042 Different responses to DNA damage and repair in ADSC in presence of UV light and H2O2Naaldijk Y
■ PP043 Amniotic fluid as a novel and rich source of stem cells for regenerative medicineOlkowska J
■ PP044 Hepatic differentiation of human mesenchymal stromal cells by lentiviral expression of transcription factorsPacher M
■ PP045 Activation of skeletal myogenic differentiation in adipose-derived stem cells by uniaxial cyclic strainPennisi CP
■ PP046 A serum free strategy correlating Stat3 activity to neurogenic potential of human umbilical cord-derived mesenchymal stem cells brings brain related regenerative medicine closerPerruisseau-Carrier C
■ PP047 Development of optimal cryopreservation protocol for suspensions of mesenchymal stem cells with application of systematic parameter optimizationPogozhykh D
■ PP048 How mesenchymal stem cells modulate the cytokines expression in the tissue engineered bladder wallPokrywczynska M
■ PP049 Integration of stem cell populations into biomaterials and their application for skin tissue regenerationRamanauskaite G
■ PP050 Clonal expansion and features of brain tumor stem cellsRoth S
■ PP051 An adjuvant anti-tumour therapy by inhibition of Hsp27 in breast cancer stem cellsRuschpler P
■ PP052 Understanding the molecular nature of resident cardiac progenitor cells using omics-based approachSamal R
■ PP053 Hair follicle melanocytes – Obtaining, differentiating, selecting, upscalinKirsten M
■ PP054 Reprogramming of bone marrow stem cells into endothelial-like cells by application of endothelial growth factorSchlegel F
■ PP055 Differentiation of murine embryonic stem cells (MESC) into hepatocyte-like cells for in vivo applicationSiegert A
■ PP056 Detection of murine embryonic stem cells after transplantation in NOD/SCID mice by in vivo imaging (bioluminescence)Stecklum M
■ PP057 Housekeeping gene stability in human bone marrow-derived mesenchymal stromal cells during adipo- / chondro- and osteogenesisStuder D
■ PP058 Bone marrow targeted liposomal drug delivery systemsTezcaner A
■ PP059 Potential of Ti surfaces to select osteogenic stem cells for repair and regenerationTillotson M
www.wcrm-leipzig.com \\ 55
Poster Presentation
■ PP060 Cardiac migration of endogenous mesenchymal stromal cells in patients with inflammatory cardiomyopathyVan Linthout S
■ PP061 Induced pluripotent stem cells of the common marmoset monkey display high cellular plasticityWiedemann A
■ PP062 Chemical modification of the epigenetic pattern imrpoved the differentiation poten-tial into hepatocyte-like and osteoblast-like cells of human ad-MSCs from old donorsYan X
■ PP064 Augmentation of urinary bladder wall with amniotic membrane seeded with mesen-chymal stem cells, regeneration of smooth muscle layer does not restore proper bladder function – Rat model research studyAdamowicz J
■ PP065 Development of a heterotypical cornea substitute using transdifferenciated umbilical cord stem cellsAlaminos M
■ PP066 Biocompatibility of laser microstrured 3D polymeric scaffoldsBaltriukiene D
■ PP067 Physical and numerical design of a fluidised bed bioreactor for stem cell expansionBenzeval I
■ PP068 In vitro modelling of squamous cell carcinoma invasionBerning M
■ PP069 Towards the reconstruction of the subcutaneous fat layerWerner K
■ PP070 Combination of long-term stable fibrin gels and porous scaffolds for engineering of volume-stable adipose tissueWittmann K
■ PP071 Cultivation of human parotid cells on a decellularized porcine jejunal segment and on a polyurethane foamBurghartz M
■ PP072 Injectable tissue engineered pulmonary heart valve implantation in a pig model Dohmen P
■ PP073 Angiogenetic factors modulate the tissue engineering of vascularized adipose tissue for an autologous soft tissue replacementDolderer JH
■ PP074 The lipid composition of liver changes significantly in dependence on nutrition – An MS and NMR studyEibisch M
■ PP075 Collagen-heparin layer-by-layer nanocoatings incorporating nanoparticles for drug releaseFerreira Duarte AM
■ PP076 PLGA-based scaffolds containing sol-gel bioactive glass enhance in vitro osteogenesis of human mesenchymal stem cellsFilipowska J
■ PP077 Micromorphological investigations of intervertebral disc degeneration using electron microscopyFriedmann A
■ PP079 Increased angiogenesis elicited by boron-containing bioactive glassGorustovich A
■ PP080 The development of a vascularized skin modelGroeber F
■ PP081 Botanical scaffold in salvage for human tissue regenerationGuhatakurta S
56 World Conference on Regenerative Medicine, November 2–4, 2011
■ PP082 Injection of mesenchymal stem cells after repair of a degenerated rotator cuff – An experimental study in rabbitsHaddad-Weber M
■ PP083 Photopolymerizable biopolymer-based hydrogels for the generation of artificial cartilage Hoch E
■ PP084 Biomechanical analysis of in-vivo performance of a novel hydroxyapatite-based bone void filler under low-amplitude and high-frequency vibrational conditionHooshiar Ahmedi SA
■ PP085 Vascularized heart tissue model to study heart diseasesIkonen L
■ PP086 Policaprolactone-based matrices as a potentially scaffolds for urinary tract regenera-tionKloskowski T
■ PP087 Blue light collagen cross linking to treat progressive myopiaKörber N
■ PP088 Cultivation and osteogenic differentiation of murine bone marrow multipotent stromal cells in micromass cultureKuchuk O
■ PP089 Development of an animal model for tissue-engineered laryngo-tracheal replace-mentsLange P
■ PP090 Usage of FGF-18 on bone marrow mesenchymal stem cell for bone regenerationLee S
■ PP091 Chondrogenic differentiation potential of human cartilage cells in pellet cultures after stimulating with TGF-ß1 and IGF-1Lochner K
■ PP093 Bone tissue engineering by porous composite carbonated hydroxyapatite/tricalcium phosphate (CHA/TCP) ceramic scaffolds and autological multipotent mesenchymal stromal cells (auto-MMSC) for repair rabbit‘s segmental diaphyseal defect Mamonov V
■ PP094 Development of a perfusion bioreactor system for the cultivation of large-scaled cell-seeded scaffoldsMilan F
■ PP095 Auricular reconstruction using a novel nanocomposite 3D scaffold and cellular engineeringNayyer L
■ PP096 Driving malignancy in human cancer cell lines on a three-dimensional (3D) collagen matrix – A basis for the development of human in-vitro tumor modelsNietzer SL
■ PP097 Development of autologos full skin transplantatMöller Y
■ PP098 Effect of uniaxial cyclic strain on the assembly and differentiation of mammalian myogenic precursorsPennisi CP
■ PP099 Development of extracellular matrix in scaffold free cartilage transplantates from in vitro to in vivo in the sheep modelPonomarev I
■ PP100 Non-invasive characterization of cartilage extracellular matrix by raman micro-spectroscopyPudlas M
■ PP101 Three-dimensional cultivation of single-cell-derived hTERT-expressing human mesen-chymal stromal cells on cancellous bone allograftRauh J
www.wcrm-leipzig.com \\ 57
Poster Presentation
■ PP102 Mineralized human primary osteoblast matrices as a model system to analyse inter-actions of prostate cancer cells with the bone microenvironmentReichert J
■ PP103 Human artificial blood vessel tissues as a pathogenesis model in vascular biomedical researchRennert K
■ PP104 Rheological characterization of criopreserved tissue-engineered human oral mucosaAlaminos M
■ PP105 The biostent – Novel concept of a viable stent structureRongen L
■ PP106 Tissue engineering for breast reconstruction: A review of current trendsSadr AH
■ PP107 Target-in: Specific gene delivery to cell types of choiceSchneider IC
■ PP108 Epidermal stem cells in cutaneous wound healingScholz P
■ PP109 Ultrastructure of cerebral intranidal arteriovenous malformation aneurysmGöhre F
■ PP110 Mechanical characterisation of a chitosan – Hyaluronic acid injectable scaffold material for spinal disc repairSchwan S
■ PP111 Comparison of equine mesenchymal stromal cells derived from different sourcesBurk J
■ PP112 Customised decellularized vascular scaffoldsSheridan W
■ PP113 Modification of porous polymer scaffolds with collagen for cells cultivationShved Y
■ PP114 Biodegradable polyurethanes for myocardial tissue regenerationSilvestri A
■ PP115 Precise microanalysis of cell cultivation media by using an amperometric biosensor system with on line microdialysisSpohn U
■ PP117 Chondrogenesis of scaffold-free bone marrow-derived human mesenchymal stem cells through cyclic, uniaxial, unconfined compressive loadingTing SYW
■ PP118 Artifical extracellular matrix composed of collagen I and sulphated glycosamino-glycans induces a proliferative dermal fibroblast phenotype in vitrovan der Smissen A
■ PP119 Development of a tissue-engineered vascularized bone implantVater C
■ PP120 Adherent cells grow at different rates on spherical microcarriers of different sizeVoigt M
■ PP121 The influence of the cell source on the sufficiency of tissue engineered heart valveWeber M
■ PP122 Biofunctionalized microfibres help to form three-dimensional (3D) capillary-like structures in a fibrin gelWeinandy S
■ PP123 Establishment of an in vitro model with human mesenchymal stem cells and micro-vascular endothelial cells onto an electrospun collagen type I/II scaffold for meniscal repairWeymüller J
■ PP124 Property for hard tissue formation in sponge scaffolds by bone marrow cells with alginate in vitroYoshikawa M
58 World Conference on Regenerative Medicine, November 2–4, 2011
■ PP125 Automated isolation of semi-adherent macrophages from a fibroblast-contaminated culture using the multifunctional, robotic cell separation system CellCelectorTM
Zoldan K■ PP126 Establishment of a femoral bone defect model for immunodeficient mice
Niederlohmann E■ PP127 Different therapeutic treatment trials to improve re-endothelialization in order to
avoid re-stenosisvon der Ruhr J
■ PP128 A novel autologous stem cell procedure for the treatment of aplastic anaemia using reprogrammed mature adult cells: A pilot clinical studyAbuljadayel I
■ PP129 Photoreceptor precursor cell transplantation: The outer segment in focusEberle D
■ PP130 Angiogenic properties of human adipose-derived mesenchymal stem cells decline with donor age due to the impairment of pro-angiogenic factors secretionEfimenko A
■ PP131 Development of a human extracellular matrix for applications related with stem cells and tissue engineeringEscobedo-Lucea C
■ PP132 Pilot trial of recombinant human growth hormone for remyelination in multiple sclerosis: Current status and preliminary safety analysisEttrich B
■ PP133 GMP quality control platform for stem cell clinical grade production in cell factoriesFerrandi C
■ PP134 Autologous fibroblast culture in the treatment of chronic venous leg ulcers using a new delivery techniqueGabr H
■ PP136 Generation of cells without mitochondrial DNA (ρ0 cells): Analysis of mtDNA deple-tion in 143B.TK- cellsHeller S
■ PP137 Functional properties of human mesenchymal stem cells (hMSC) derived from multiple sclerosis patients as compared to those of healthy donorsKassis I
■ PP138 Prolonged clinical effects of mesenchymal stromal cell therapy in patients with chronic coronary artery disease – 24 months follow-upKastrup J
■ PP139 Blood derived stem cells: Therapeutic applications in the ophthalmology fieldMarfè G
■ PP140 10-year experience in autologous disc chondrocyte transplantation (ADCT): A critical clinical review of 115 casesMeisel HJ
■ PP141 Bone marrow mononuclear cells effect on dermal fibroblast proliferationMenéndez Menéndez Y
■ PP142 Antigen specific CD8 T cell transmigration into tumoursOelkrug C
■ PP143 Survival and functional restoration of human fetal ventral mesencephalon following transplantation in a rat model of Parkinson’s diseaseMoellers S
■ PP144 Expanded adipose derived stem cells for veterinary medicine applicationsSmirnova N
■ PP145 MCAM/CD146 expression on human mesenchymal stromal cells influences prolifera-tion and maintenance of hematopoietic stem and progenitor cells during co-cultureStopp S
www.wcrm-leipzig.com \\ 59
Poster Presentation
■ PP146 A new specially formulated defined xeno-free tissue culture medium for growth and expansion of human AT-MSCsTallone T
■ PP147 Human cardiac biopsy-derived cells reduce Coxsackievirus B3-induced myocarditis and require interferon-gamma for their activationVan Linthout S
■ PP148 Formation features of ischemic necrosis and myocardium cryonecrosisBabaieva G
■ PP149 Visualization of DMSO diffusion in engineered constructs for long term-storageBernemann I
■ PP150 Normothermic acellular ex vivo liver perfusion (NEVLP): Development of a new method for preservation, assessment and repair of marginal organs – shown in a pig model with livers donated after cardiac death (DCD)Boehnert MU
■ PP151 A new short time rat model of mucosal inflammationBreitrueck A
■ PP152 “Hypoxic protocol“ for MMSC ex vivo expansion to meet needs of regenerative medicineBuravkova L
■ PP153 Murine and human postnatal ENS progenitor cells integrate into murine bowel in vivoDettmann H
■ PP154 New heterocyclic compounds for regeneration of mammalian cochlear sensory cellsWank U
■ PP155 Fetal liver regeneration in ratsElchaninov A
■ PP156 Bone marrow-derived stem cell transplantation in a mouse model of retinal degene-rationEnzmann V
■ PP157 Bone marrow derived multipotent stromal cells promote myocardial fibrosisFatkhudinov T
■ PP158 Synthetic vesicles: Photo cross-linked and pH sensitive polymersomes as bionanore-actorsGaitzsch J
■ PP159 Effect of topical nitric oxide donor (0.2 % glyceryl trinitrate) on wound healing in diabetic wistar ratsGhori V
■ PP160 Development of a large animal model for intervertebral fusion in lumbar spinal motion segementsHohaus C
■ PP162 Nonlinear finite element model of the spine and investigating the role of muscle under compression loadKhaksar FM
■ PP163 Bone regenerates via dedifferentiation of osteoblasts in the zebrafish finWeidinger G
■ PP164 Establishment of a large animal model for implantation of decellularized esophagus scaffolds: A pilot studyKoch H
■ PP165 Macrophage infiltration is inhibited by genipin cross-linking of decellularized esophagus scaffoldsKoch H
■ PP166 Angiogenesis followed by transplantation of autologous and allogeneic cellsMakarov A
60 World Conference on Regenerative Medicine, November 2–4, 2011
■ PP167 Service offer: Flow & image cytometry and in vivo imagingMittag A
■ PP168 Effects of exposure time on the luminescence properties of biologically formed apatite in simulated body fluidMozafari M
■ PP169 Evaluation of intra-osseous defects regeneration treated by platelet rich plasma using silver-stained nucleolar organizer regions (agnors)Nassan M
■ PP170 Synovial membrane derived mesenchymal stem cells in hyaluronic acid scaffold transplantation for regeneration of cartilage defectsBekbolsynov D
■ PP171 Immune cells-targeted delivery of mannan-coated superparamagnetic iron oxide nanoparticles for detection of micro-metastasisPark IK
■ PP172 The role of the integrator complex during planarian regenerationReuter H
■ PP174 TGF-beta superfamily member activin A improves survival of spiral ganglion cells in vitroWarnecke A
■ PP175 In vitro evaluation of promising key factors for regenerative stroke treatment approachesWielsch B
■ PP176 Impaired endothelial regeneration after human parvovirus B19 infection of circulat-ing progenitor cells with endothelial regenerative potential (CERP)Zobel T
■ PP177 The use of zinc finger in molecular diagnosticsAllelein S
■ PP178 CXCR4 expression in human mesenchymal stem cells enhances in vitro migrationAndersen RK
■ PP180 An agent-based framework to simulate cell-cell communication of adult stem cell populations in vitroBecker T
■ PP181 A screen for ion channels and transcription factors involved in zebrafish heart regenerationChan WH
■ PP182 Non-invasive and non-destructive in situ monitoring of endothelial cells cultured in fibrin gels under perfusion bioreactor conditions by positron emission tomography imagingChouinard JA
■ PP183 The protein and lipid composition of coronary atherosclerotic plaque and its structural analysisFaghihi S
■ PP184 Regenerating myeloperoxidase activity contributes to cellular termination of inflammationFlemmig J
■ PP185 A novel molecular method for earliest diagnosing cancersHan-You X
■ PP186 The new carcinogenesis theory of gene multiple hitsHan-You X
■ PP187 Authentication of cells in therapy research applying cytogenetics and genome wide high resolution single-nucleotide polymorphism arrayHolland H
www.wcrm-leipzig.com \\ 61
Poster Presentation
■ PP189 Towards a genetic screening test for dyslexia allowing functional regeneration: Steps towards identification and analysis of genetic risk factorsKirsten H
■ PP190 Effect of aging and estradiol on membrane linked functions in female rat brainKumar P
■ PP191 Biodegradable microcarriers as cell delivery vehicle for in vivo transplantation and magnetic resonance monitoringLovati AB
■ PP193 Chemopreventive activities of Curcumin and Diclofenac in early colon carcinogenesis: Molecular mechanisms involved and down-regulation of COX-2 and iNOS through suppression of NF-kappaB activationRana C
■ PP194 Determination of peptide composition of animals‘ heart extractsRogoza L
■ PP195 Metabolic and gene expression profile of MMSCs under low oxigenRylova J
■ PP196 Magnetic bead-based lab-on-a-chip system for the point-of-care diagnosticsSandetskaya N
■ PP197 Planarian Smed-POU5, a POU transcription factor of subclass V, maintains the stem cell identity and self-renewal ability of adult stem cells in Schmidtea mediterraneaSchmitz H
■ PP198 The analysis of native and oxidatively-modified phospholipids and blood lipoproteins by MALDI-TOF mass spectrometryTeuber K
■ PP199 Human parvovirus B19 (B19V) infection of circulating cells with endothelial regene-rative potential induces apoptosis via a caspase-8/-10 dependent mechanismZobel T
■ PP200 Anti-inflammatory effects of bovine colostrum on the intestinal epitheliumBodammer P
■ PP201 Immunomodulatory effects of benzo(a)pyrene influencing the outcome of infection with salmonella entericaFueldner C
■ PP202 Transforming growth factor b mRNA expression in early stage and metastatic endo-metrial cancer microenvironment versus normal endometriumGiannice R
■ PP203 Reciprocal interaction effects on MMSCs and PBMCs proliferation and viabilityGornostaeva A
■ PP204 Acetylsalicylic acid stabilizes immune functions of macrophagesKnauer J
■ PP205 Role of the danger signal molecules S100A8 and S100A9 in the antiviral response of epithelial cellsKerkhoff C
■ PP206 Modelling hematological parameters after irradiationOelkrug C
■ PP207 An indispensable role of CD2 in initiating T cell proliferation in the patients suffering from visceral leishmaniasisSinha S
■ PP208 The role of mast cells and Weibel-Palade-bodies in mesenteric infarctionSommer HJ
■ PP209 Approaches to T regulatory cell therapy in autoimmunity and GVHDTheil A
■ PP210 Investigation of corrosion of WE43 MG-alloy for biodegradable implants applicationsAscencio M
62 World Conference on Regenerative Medicine, November 2–4, 2011
■ PP211 Effect of extracellular matrix on proliferation and adhesion properties of bone marrow mesenchymal stem cells and hair follicule stem cells: Utility for tissue and organ regenerationBajek A
■ PP212 Characterization of agarose gels in an ElectroForce® test systemBöhm R
■ PP213 PLGA dynamic degradation and mechanical propertiesBöhm R
■ PP214 Multifunctionalized nanoporous silica nanoparticles for tissue engineering applicationsChristel A
■ PP215 Application of upcyte® hepatocytes on 3D cell cultureDähn C
■ PP216 A comparative PM-IRRAS and ellipsometry study of the interaction of bovine serum albumin with a gold surfaceDargahi M
■ PP217 Phosphorylation of polymers and their electrospinning- towards development of biomimetic osteoconductive and osteoinductive matrices for bone regenerationDatta P
■ PP218 A new biodegradable collagen cell carrier for tissue engineering of matrix-stabilized urotheliumVaegler M
■ PP219 Lockyballs: Bottom-up approach for rapid in vivo 3D tissue biofabricationDavid Alencar de Sena Pereira F
■ PP220 Does platelet-derived-growth-factor-AB in autologous platelet-rich plasma gels influence the tissue development of human umbilical cord artery smooth muscle cells?Dietrich M
■ PP221 Influence of a calcium carbonate scaffold on human mesenchymal stem cells prolifera-tion and differentiationDivieto C
■ PP222 Regeneration of decellularized equine pericardial patches implanted into the systemic circulationDohmen P
■ PP223 An experimental study of stentless decellularized xenografts implanted into the aortic position of the juvenile sheepDohmen P
■ PP224 Functional validation of decellularized extracellular matrix preparations derived from mesenchymal stromal cells overexpressing jagged-1Duryagina R
■ PP225 Nanostructuring of titanium by high presure torsion influences mesencymal stem cell response and bacterial adhesionFaghihi S
■ PP226 Biological evaluation of a novel nanocomposite of hydroxyapatite/layered double hydroxides/gelatinFayyazbakhsh F
■ PP228 Composite hydrogel scaffold for nerve tissue engineeringBorgio L
■ PP229 Fabrication of scaffold matrix from goat lung tissue and its biocompatibility study using Hep G2 cell line for tissue engineering applicationGupta S
■ PP230 Characterization of iridium / titanium oxide coatings for biomedical applicationsHabibzadeh S
www.wcrm-leipzig.com \\ 63
Poster Presentation
■ PP231 Interaction of Ni(II)-NTA-modified poly(ethylene imine)-maltose with HIV-derived GP160 capturing in dendritic cellsHauptmann N
■ PP232 Gold nanoparticle mediated cell manipulation using ultrashort laser pulses for cell perforation and transfectionHeinemann D
■ PP233 Synthesization and characterization of magnetic nanoparticles via inert gas conden-sationHennes M
■ PP234 Functionalization of 3D porous bone substitutes using layer-by-layer technologyJacobi A
■ PP235 Biomimetic control of cell behaviour by substrate independent modification with “Click&Seed“ systemJaroš J
■ PP236 Impact of sulfated glycosaminoglycans on monocyte to macrophage differentiationKajahn J
■ PP237 Osteogenesis by bone marrow cells in novel hybrid alginate/calcium phosphate sponge scaffoldKakigi H
■ PP238 Influence of pore geometry and growth factor (BMP-2) application on in-vitro tissue formation in hydroxyapatite scaffoldsKommareddy KP
■ PP239 In vitro modulation of human corneal endothelial cell behaviors using topographical and biochemical cuesKoo S
■ PP240 Martensitic transformation and magnetic properties of freestanding single crystalline Fe70Pd30 thin filmsMa Y
■ PP241 Nanoparticles for controlled release of therapeutic molecules after strokeI. Santos M
■ PP242 The interaction between mouse mesenchymal stem cells and poly (3-hydroxy butyrate) nanofibrous scaffolds for tissue engineering applicationsMasaeli E
■ PP243 Neuronal protection by nanoparticle mediated rolipram applicationScheper V
■ PP244 Combination of self-assembling peptides and scaffolds: Characterization, protein delivery and biological performanceMonleon-Pradas M
■ PP245 Heat-treatment effects on the formation of phase pure nanocrystalline Mg2SiO4 bioceramic intended for bone tissue engineeringMozafari M
■ PP246 Forsterite addition to bioactive glass as a novel hybrid nanocomposite to improve its mechanical and biological propertiesMozafari M
■ PP247 Chitosan/gelatin scaffolds with controlled mechanical properties engineered for soft tissue applicationsMozafari M
■ PP248 Nerve regeneration enhancement of polyvinyl alcohol nanofibrous scaffolds by adding chitosanMozafari M
■ PP249 Finite element analysis of a novel scaffold based on gelatin and bioactive glass as a substitution of femoral head tissueMozafari M
64 World Conference on Regenerative Medicine, November 2–4, 2011
■ PP251 Chondroitin sulfate nanoparticles for delivery of growth factors in cornea regenera-tionPárraga M. JE
■ PP252 Restricted microdomains for time-lapsed neural precursor cells studies by laser assisted micropatterningPerez-Hernandez H
■ PP253 Influence of glycosmaminoglycan sulphation on the interaction with interleukin-8Pichert A
■ PP254 Design of a versatile surgical patch Prost N
■ PP255 Management of complex dermal wounds using a new collagen cell carrier (CCC): An in vivo evaluation of split skin graft transplantation combined with CCC in ratsHeld M
■ PP256 Evaluation of biocompatibility and biodegradation of a novel collagen cell carrier (CCC) for in vivo applicationHeld M
■ PP257 Tailor-made collagen-based matrices for cell culture, medicine and diagnosticsReinisch H
■ PP258 Next generation deep brain stimulating devices with neuropil-mimicking cell coverRichter A
■ PP259 Design of positively charged hydrogel systems for the in-situ immobilization of enzymes through fast cross-linkable monomers and macromonomersRichter A
■ PP260 New nonwoven-based scaffold structures for mesenchymal stem cellsRoß R
■ PP261 An innovative method to produce biodegadrable polymer scaffolds for tissue engineeringSantos L
■ PP262 Upcyte® microvascular endothelial cells are able to repopulate an acellularized scaffoldScheller K
■ PP263 Resorbable ceramics based on calcium pyrophosphate and alkali polyphosphatesShiryaev M
■ PP264 Generation of human corneal endothelial cell sheets using smart cell culture carriersTeichmann J
■ PP265 Encapsulation of adipose-derived stem cells in alginate membrane for regenerative medicineTosca MC
■ PP266 Silk fibroin film as adipose derived stem cell scaffolds for skin advanced therapyTosca MC
■ PP267 Adipose stem cells and pancreatic islets on fibroin non-woven scaffolds: Technological characterization and cultureTosca MC
■ PP268 To better define the surface density of vitronectin on TCPS for the long-term culture of pluripotent human embryonic stem cellsYap L
■ PP269 Analysis of the migration of the stromal cells of bone marrow and fibroblasts of rabbit in the collagen and fibrin gelsYudintceva N
■ PP270 Smart methylcellulose hydro-gel for engineered human cardiac progenitor cell (hCPCs) sheetsZamperone A
www.wcrm-leipzig.com \\ 65
Poster Presentation
■ PP271 Collagen cell carrier for neural cell culturesZhang Y
■ PP272 The search for new stem cell research rules between the poles of the recent pre-implantation genetic diagnosis sentence of the federal supreme court and the impact of reprogrammed stem cells in GermanyFaltus T
■ PP273 Stemm cells & ethics: Negative propaganda in public discourse and the necessity of new ways to handle itReichardt JO
■ PP274 Overview of Japanese draft guidelines on ensuring quality and safety of products derived from engineered human stem cellsSato Y
■ PP275 Setting standards: European and international standardization landscape in the field of medical devices utilizing tissuesWenzelewski K
■ PP276 Towards a genetic screening test for dyslexia: A survey on acceptanceWilcke A
66 World Conference on Regenerative Medicine, November 2–4, 2011
Vertrauen erfahren
The Beetles
Jetzt noch besser mit dem optionalen Fender®-Soundsystem.
Das Auto.
Ihr Volkswagen Partner
Volkswagen Automobile LeipzigMerseburger Straße 200 • Delitzscher Straße 190 • Richard-Lehmann-Straße 118Torgauer Straße 331 • Autohaus Muldental, Leipziger Straße 93, 04668 Grimma
www.wcrm-leipzig.com \\ 67
evening funCtions
evening funCtions
oPening Ceremony (hall 1)
and get-together (exhibition
area)
WeDneSDAy, november 2, 2011
Regenerate, Re-Energize, Reminisce and
Relax at the opening ceremony! Don’t
miss this chance to mingle and mix with cutting edge researchers from every corner of
the globe as well as the leaders of the companies who are involved in translating this
research into cell and tissue engineer ed products.
Be our guest at the opening ceremony (05:30 pm at Hall 1) and, thereafter, at the get-
together in the exhibition area (included in the registration fee; registration required).
Poster Party (Poster exhibi-
tion area floor 0)
thurSDAy, november 3, 2011
In order to give each delegate adequate
opportunity for an intensive discussion
of the posters we invite you to join an
informal Poster Party with beer and
snacks (included in the registration fee;
registration required).
Poster authors are requested to be present at their posters.
Start: 05:30 pm at the Poster Exhibition Area Floor 0
Award ceremony for best abstract and best poster: 07:00 pm
Best Abstract and Best Poster Award kindly supported by Pluristem Therapeutics Inc.
68 World Conference on Regenerative Medicine, November 2–4, 2011
With me At
gondwanalandDINNERHAVE
gondwanalandENJOY
With me At
gondwanalandRELAX
With uS At
gondwanalandCOMMUNICATE
© L
uc
via
tou
r / w
ww
.Lu
cnix
.be
© A
dam
anti
os
© t
ho
rste
n b
ach
ner
© h
ans
hill
ewae
rt /
cc
-by
-SA
-3.0
www.wcrm-leipzig.com \\ 69
evening funCtions
troPiCal exPerienCe world
gondwanaland
friDAy, november 4, 2011
Where dinosaurs wandered over the
landmass...
More than 17,000 different tropical plants,
around 300 exotic animals and the kind of
virgin rain forest which once characterised
the lost continent of Gondwana – all of
this comes alive in the unique Tropical
Experience World Gondwanaland at
Leipzig Zoo. Exciting tracks lead you
through the rainforest in a huge tropical
hall where animals from these three
continents will cross your path. Birds will
fly through the air and monkeys climb in
the trees...
Be our guest in this unique scenery and don‘t miss the chance to mingle with colleagues
and friends in the evening of November 4, 2011.
Tickets can be purchased at the registration desk.
Price: 70.00 € including VAT, guided tour of Gondwanaland, food and beverages
Meeting point: Entrance Gondwanaland (Tempelfoyer) at 06:30 pm
70 World Conference on Regenerative Medicine, November 2–4, 2011
\\ exhibition Plan
LeveL +1
exhibitorS
Company Booth
Analytik Jena AG Jena (D) 22
ASKION GmbH Gera (D) 2
Auto Q Bioscience Ltd. Theale, Berkshire (UK) 39
BD Biosciences Erembodegem (BE) 37
Beckman Coulter GmbH Krefeld (D) 5
BioLegend GmbH Fell (D) 36a
Biometra GmbH Göttingen (D) 22
Biomomentum Inc. Laval, QC (CA) 32
BIO-NET LEIPZIG Technologietransfergesellschaft mbH Leipzig (D) 10
Biosafe S.A. Eysins (CH) 45
biosaxony e.V. Dresden (D) 11
biosaxony Management GmbH Dresden (D) 11
CaridianBCT, Inc. Lakewood, CO (USA) 28
Cell Cryogenics Ltd. Cambridge (UK) 35
Cell Guidance Systems Ltd Bar Hill, Cambridge (UK) 40
CellGenix GmbH Freiburg (D) 36
Cenibra GmbH Bramsche (D) 26a
hall 1
hall 2 hall 3
hall 4 hall 5
escalators
lift
stairs
36a 30a 26a27a31a
3839
3637
3435
3233
3031
2829
4041
4746
42 43 44 45
2627
25 24 23 22 21 20 19 17 16 15 14 13 12 6 5 4 3 2 111 10 9 8 718
catering catering
www.wcrm-leipzig.com \\ 71
exhibitors
Company Booth
German Society Industrial Cell Technology Lübeck (D) 33
EBERS Medical Technology S.L. Zaragoza (ES) 27
eBioscience Vienna (A) 20
Edizioni Altera srl Rome (IT) 30
Ewald Innovationstechnik GmbH Bad Nenndorf (D) 1
Fraunhofer Group for Life Sciences Hanover (D) 7
Fraunhofer Institute for Cell Therapy and Immunology Leipzig (D) 7
Fraunhofer Institute for Interfacial Engineering and Biotechnology Stuttgart (D) 7
GE Healthcare Munich (D) 34
German Society for Regenerative Medicine e.V. Frankfurt / Main (D) 9
GeSim mbH Großerkmannsdorf (D) 29
Greiner Bio-One GmbH Frickenhausen (D) 21
Hiss Diagnostics GmbH Freiburg (D) 24
Hugo Sachs Elektronik – Harvard Apparatus GmbH March-Hugstetten (D) 43
InTech – Open Access Publisher Rijeka (HR) 8
Janvier SAS St Berthevin (FR) 41
Jenpolymers Ltd. Jena (D) 16
Labotect GmbH Göttingen (D) 47
Life Technologies GmbH Darmstadt (D) 3
MACHERY-NAGEL GmbH & Co. KG Düren (D) 42
Nikon GmbH Düsseldorf (D) 18
ORTHOGEN Lab Services GmbH Düsseldorf (D) 6
PAA Laboratories GmbH Cölbe (D) 23
PeproTech GmbH Hamburg (D) 15
pluriSelect GmbH Leipzig (D) 27a
Projektträger Jülich, Forschungszentrum Jülich GmbH Jülich (D) 4
PromoCell GmbH Heidelberg (D) 19
Regenerative Medicine Initiative Berlin-Brandenburg (RMIB) Berlin (D) 30a
R&D Systems GmbH Wiesbaden (D) 25
Roche Diagnostics GmbH Mannheim (D) 12
ROWIAK GmbH Hanover (D) 44
Scottish Stem Cell Network (SSCN) Ltd. Roslin, Midlothian (UK) 31
SERVA Electrophoresis GmbH Heidelberg (D) 38
Sysmex Digitana AG Horgen (CH) 17
Thermo Fischer Scientific Langenselbold (D) 13
Translational Centre for Regenerative Medicine (TRM) Leipzig Leipzig (D) 9
V-Care Biomedical GmbH Leipzig (D) 46
VetCell Kingham, Oxfordshire (UK) 26
Viscofan Bioengineering Weinheim (D) 14
72 World Conference on Regenerative Medicine, November 2–4, 2011
Athersysi n c.
media Partners
sPonsors and exhibitors
Partners
Partners and sPonsors
74 World Conference on Regenerative Medicine, November 2–4, 2011
bundesministerium für bildung und forsChung
Die Biowissenschaften haben in den letzten Jahren einen entscheidenden Beitrag zum
tieferen Verständnis des Lebens geleistet. Daraus ergeben sich neue Aufgaben und
Arbeitsfelder für das Bundesministerium für Bildung und Forschung (BMBF). Die Rege-
nerative Medizin ist eines dieser wichtigen Handlungsfelder, welches auch im aktuellen
Rahmenprogramm „Gesundheitsforschung“ der Bundesregierung verankert ist.
Um den komplexen transdisziplinären Anforderungen von der Forschung bis zur
klinischen Anwendung regenerativer Therapien gerecht zu werden, hat das BMBF
zusammen mit den zuständigen Landesministerien spezifische Translationszentren in
Berlin (BCRT), Leipzig (TRM) und Rostock (RTC) gegründet. Mit der Bekanntmachung zur
Förderung Bilateraler Verbundprojekte mit dem Californian Institute for Regenerative
Medicine (CIRM) zur Entwicklung und Validierung von Methoden und Verfahren für die
Regenerative Medizin wird zudem die Bedeutung der internationalen Zusammenarbeit
weltweit anerkannter Forschungsgruppen in der RegMed hervorgehoben. Diese Maß-
nahmen werden durch die „Nationale Forschungsstrategie BioÖkonomie 2030“ sowie
institutionelle Förderungen von außeruniversitären Forschungseinrichtungen, auch unter
Beteiligung der Wirtschaft, ergänzt.
Weitere Informationen und kompetente Beratung zu unseren Fördermaßnahmen und
Bekanntmachungen erhalten Sie über den Projektträger Jülich (PtJ).
www.ptj.de/regenerative-technologien
www.wcrm-leipzig.com \\ 75
endorsing Partners
Tissue and Cell Engineering Society
endorsing Partners
www.wcrm-leipzig.com \\ 77
ComPanies in saxony
sPeCial: ComPanies in saxony
the WorLD conference on regenerAtive meDicine iS kinDLy
SuPPorteD by the SAxony StAte miniStry for Science AnD the ArtS
Biosaxony alliance \\ www.biosaxony.com
The biosaxony alliance consits of biosaxony e.V and
biosaxony Management GmbH. biosaxony e.V. is a
registered association representing biotechnology and
related areas from materials science to medical equipment throughout the German region
of Saxony. The aims of biosaxony Management GmbH are to initiate projects between
industry and science, to network services and expertise, and to leverage synergies to
boost the development of the biotech industry and publicize the region’s expertise.
BIO-NET LEIPZIG Technologietransfergesellschaft mbH \\ Leipzig \\ www.bio-city-leipzig.de
Factors for sustainable growth of biomedical companies are favorable
structural and financial support and a network that has proven its value
and works on an interdisciplinary basis. That’s exactly what makes BIO
CITY LEIPZIG so unique. Here you can find everything that successful
biomedical businesses may need. BIO-NET LEIPZIG GmbH is your
partner of choice for business development, settlement, and R&D
networks in the area of Leipzig.
V-Care \\ Leipzig \\ www.v-care-biomedical.com
V-Care Biomedical GmbH provides high-quality, innovative products
from the field of regenerative medicine, as well as a strong emphasis on
service. This includes products from the field of regenerative medicine and
innovative wound treatment products for both people and animals.
78 World Conference on Regenerative Medicine, November 2–4, 2011
Don´t miss the V-Care presentation:
Thursday, November 3, Session “Skin & Soft Tissue Regeneration“ (04:00–05:30 pm)
Titel “Update on ATMPs in veterinary medicine: From lab to patient´s site“
Presenter: Andreas Emmendörffer
Visit the V-Care booth at the exhibition area.
Prima BioMed GmbH \\ Leipzig \\ www.primabiomed.com.au
Prima BioMed GmbH is a subsidiary of the ASX
listed Australian health care company Prima BioMed
Ltd. The Company is focused on technologies in the
fields of cancer immunotherapy and immunology. Prima’s lead product is the CVac™
ovarian cancer therapy treatment. The Company’s broader, long term goal is to develop
commercial cancer treatment technologies and programs for global markets.
Don´t miss the Prima BioMed presentation:
Wednesday, November 2, Session “Signalling & Cancer“ (11:00 am–12:30 pm)
Titel “Autologous dendritic cells pulsed with recombinant human fusion protein [mucin
1-glutathione S-transferase] coupled to oxidized polymannose as maintenence treatment
of epithelial ovarian cancer in remission: A clinical trial update“
Presenter: Matthew Lehman
PluriSelect GmbH \\ Leipzig \\ www.pluriselect.com
PluriSelect provides customers in academic science,
research & development and diagnostics with
efficient tools for cell and protein separation. For each
segment, we develop separation tools to isolate target cells and / or proteins directly
from whole blood, buffy coat or other biological fluid. The cell and protein separation
tools developed by pluriSelect are versatile in application and form the basis of research
in cancer, rheumatic illnesses, arteriosclerosis and allergies.
www.wcrm-leipzig.com \\ 79
ComPanies in saxony
GeSIM \\ Grosserkmannsdorf \\ www.gesim.de
GeSiM is a leading supplier of instrumentation and services for low-
volume liquid handling, microfluidics, and microcontact printing. Being
in business for more than 16 years, GeSiM focuses on off-the-shelf
products (E.g. non-contact micro arrayers) as well as tailored solutions.
Visit the GeSIM booth at the exhibition area.
Saxony Economic Development Corporation \\ Dresden \\ www.wfs.sachsen.de
The Saxony Economic Development Corporation
(WFS) builds bridges: For Saxon enterprises
heading off into the world and for investors
heading for Saxony. As an instrument of economic promotion, the WFS makes a vital
contribution to the sustained, positive development of Saxony’s economy. WFS activities
focus specifically on attracting innovative, competitive enterprises to Saxony, thus, safe-
guarding existing jobs and creating new ones, strengthening those enterprises which are
already located here by initiating sales promotion measures and arranging cooperations
as well as launching effective and efficient locational marketing campaigns.
Further saxony biotech companies will be represented by biosaxony at the
exhibition area:
\\ Vita34 AG, Leipzig, www.vita34.de
\\ PARTEC GmbH, Görlitz, www.partec.com
\\ Biotype Diagnostic GmbH, Dresden, www.biotype.de
\\ UroTec GmbH, Dresden, www.urotec.de
80 World Conference on Regenerative Medicine, November 2–4, 2011www.eventlab.org
We make your conference a success to remember.
www.wcrm-leipzig.com \\ 81
information
general information
Conference Coordinator
Fraunhofer Institute for Cell Therapy
and Immunology
Professor Frank Emmrich
Perlickstr. 1 | D-04103 Leipzig
www.izi.fraunhofer.de
Conference Office
event lab. GmbH
Dufourstr. 15 | D-04107 Leipzig
phone: +49 163 4419072
fax: +49 341 240596-51
e-mail: [email protected]
Conference Dates | Opening Hours
Registration Desk
\\ Wednesday, November 2, 2011:
09:00 am–08:00 pm
\\ Thursday, November 3, 2011:
08:00 am–08:00 pm
\\ Friday, November 4, 2011:
08:00 am–06:00 pm
Speakers Preview
The Speakers preview room, lecture hall 12
(level +2), will be open all time during the
conference. Please come to the speakers
preview room as soon as possible and no
later than 30 minutes before your session
starts. Presentations will be collected
and delivered to the lecture hall via the
computer network.
Language
The official language of the conference is
English.
Participation / Name Tag
Official conference name tags will be
required for admission to all conference
functions, scientific sessions and exhibition
areas. Individuals who lose their name tags
will have to pay a fee of 30 € to obtain a
replacement tag.
Exhibition Information
The exhibition of the World Conference
on Regenerative Medicine, featuring
commercial displays of pharma ceutical and
product companies, medical publishers will
be located in the foyer area (level +1).
The exhibition will be open on:
\\ Wednesday, November 2, 2011:
11:00 am–08:00 pm
\\ Thursday, November 3, 2011:
09:00 am–05:30 pm
\\ Friday, November 4, 2011:
09:00 am–05:30 pm
The Get-together will take place in the
exhibition area on Wednesday evening.
82 World Conference on Regenerative Medicine, November 2–4, 2011
Internet
Free of charge internet station can be
found on floor +2 in front of room 10/11.
W-LAN Vouchers can be purchased at the
registration desk (cash payment only).
\\ Voucher (3 hours): 5.00 €
\\ Voucher (1 day): 13.00 €
\\ Voucher (3 days): 30.00 €
Poster Presentation
The poster exhibition will take place on
level 0 in the Congress Center Leipzig.
The poster exhibition will be opened
all-day on the conference days. The Poster
Party, at which each presenter must be
available for discussion, will take place on
Thursday, November 3, 2011, at 5:30 pm..
Materials for putting up the posters will be
provided. Posters must be removed from
the board until the end of the conference.
The meeting staff will remove posters not
taken down by Friday, November 4, 2011,
and the meeting organizers cannot
take any further responsibility for the
material.
Public Transport
The official conference name tag allows
free use of the public transportation
system within Leipzig (including from / to
the airport). Please make sure to have it
with you all the time and be prepared to
present your ID card to the conductors as
they might ask for it to proof the validity
of the name tag.
Certification
The Medical Association of Saxony
certificates the conference with continuing
education points. Certificates will be
issued at the registra tion desk.
www.wcrm-leipzig.com \\ 83
information
Stadtplan
Adolf-
Emil-weg
e-Otto--Platz
str.
ski-straße
Fuchs-
Funkenburg-straße
Leibniz-straße
Färberstr.Straße
Rosental-gasse
Lortz ingstr.Jacob-
str.
Hinrichsenstraße
Parthen-
Keilstraße
Packhof-str.
Am H
all.
Tor
Naun-
dörfchen
Thoma-
str.
sius-
straßeLessing-
Poniatowski-plan
C.-M.-v.
Weber-S
tr.
Mendels
sohnst
r.
Alexan-
derstr.
rstraße
Schreberstr.
Wilh.-
Se
Dimitroffstraße
Mar
kthall
en-
straß
e
Brüderstr.
straße-Sch
nel-
r-Str.
Leplay-str.
Jablon
owski
str.
Turne
r-str
.
1 Webergasse
Fried
richs
tr.
Sternwarte
Auguste-Schmidt-Str.An d.Verfassungs-lindeSee- burg- straße
Stern- wartenstraße
Ost-l
Amalie-Winter-Pl t
Joh.-al
leeTeubnerstr.Seemannstr.
Reich-
Johannisgasse
Goldschm.-
straße Plato-
straß
e
berg
platz
Guten-
Rabenstein-platz
Spohr-str.
Perth
esstr
aße
1
Sche
rlstra
ße
Lang
e
Stra
ße
Ludw
ig-E
rhar
d-S
traße
Ranftsche G.Marien-platzAn
der
Milch
insel
Inse
lstra
ße
Salom
onst
raße
Salo
mon
stra
ße
Inse
l-
s
tr.Chopin- straße
Egel- straße
Büttnerstraße
DörrienstraßeLittstraße
Czermaks G.
Schütze
nstr.Ha
hne-
kamm Ho
fmeis
ters
traße
Dohnanyistraße
H.- Poeche-Straße
W.-gartenstr.
Lagerh.Str.
Reudnitzerstr.
Max-
Beckm.-Str.
Reiche
lstr.
Manet-
str.
Rudolphstr.
O.-Schill- Str.
Apels Garten
Zentr
al-
straß
e
Zimmerstr.
2 Alter Amtshof3 Schrebergäßchen
2
M.-Luther- Ring
Lotter- str. H.-Licht-Str.
Markgrafen-
Ratsfreischul- str.
Burgstr.
Gustav-Mahler-
Str.
3
Schloßg.str.
Tho mas-Thomasg.
Klos
terg
.
F leis
cherg
asse
Kleine Fleischerg.
1 Matthäi-kirchhof
1
Johanna-
park W.-Leuschner-Platz
Roß-
Ring
Martin- Luther-
Wächterstraße Windm
-Allee
F.-Lass
alle-Str.
Nürn
berg
er
S
traße
Talst
raße
Goldschmidtstraße
Har
kort-
str.
Friedrich- Ebert- Straße
Goer
dele
rring
ring
Elster-
straße
Gottsched-straße
Bose
str.
Nikisch-platz
Hainstraße
Kath
arin
enst
raße
MarketSquare
Grimmaische Str.
kirchhof
Ditt
-
richr
ing
Barfußgäßchen
Gr.
Salzg.
Tröndlinring
Kolonnadenstraße
Kollw
itz-
Str.
Uni
vers
itäts
-st
r.N
ikol
aist
raße
Brühl
Burg-platz
Pete
rsst
raße
Neu
-
mar
kt
R.-Wagner-Platz
Richard-Wagner-Str.
Doro-theen-
platz Preußerg.Kupfergasse
Peters-kirchh. Magazing.
Gewandg.
Schuhm.-g.
Reich
s-st
raße
R o s e n t a l
Humbo
ldt-
straße
Uferstraße
Straße
Pfaf
fend
orfe
r
MainStationWilly-
Brandt-
Platz
Löhr
- s
traße
Ger
bers
traße
Nor
d-
stra
ße
W.-Liebknecht-Platz
Stra
ße
Ernst-Pinkert-Straße
Brandenbu
rger
Straße
F.-List-Platz
straße
ring
Augustus-platz
Geo
rgi-
Johannis-platz
Prager Straße
Ger
icht
sweg
Schil- lerstr.
Goe
thes
traße
Ritte
rstr.
Brühl
GrimmaischerSteinweg
Que
r-
st
raße
Kreuz- straße
straß
e
Que
r-
st
r.
Ritterstr.
plat
z AlterJohannis-friedhof
Kleingarten-anlage
Johannistal
Kurt-Schumacher-
Str.
Preu
ßens
eite
4 4 Simson-platz
Gr. Brockhaus
Lurgenst.-Steg
Große
Wiese
Joh.-E
ck-
Str.
Step
han-
weg
Mecklenb. Str.
Sporthalle
Brüder-
Bauh 1
Institut fürMetereologie
Universität
West-platz
Böttcherg.
Nonnenmühl-gasse
Sporerg.
Jahnallee
Ranstädter Steinweg
Sach
sen - seite
Dresdner Str.
R.-Wagner-Straße
Dittri ch -
Grün
ewald
str.
Fritz-v.Harck-Anlage
Nikolaikirchhof
Nasch-markt
park
Leibnizweg Herre
nalle
e
e
Parthe
Primavesistraße
Nord-platz
Kicker lings-
berg
Springer-
Karl-Rothe-
S
traßeStraße
Roscherstr.Eu
tritz
sche
r Stra
ße
Gneisenaustraße
Berli
ner
Roscher- straße
Straße
Schlößchen-steg
Michaelisstr.
Stadt-bad
(geschlossen)
Nordkirche
Lumumbastraße
straße
Wittenberger Straße
Haferkornstraße
Zerbster-
Straße
Hohmann- straße
Bitterfe
lder
S
traße
Dessauer
Straße
Apelstraße
Bal
zacs
traße
Lade
straß
e
H.-Kapelle-Straße
Fliederhof
Rackw
itzer
str.
AdenaueralleeAm Goth. Bad
Rosa-
Luxemburg- S
traße
Kucheng.str.
Atrium-
str.
Eilen- burger
Täubchen-
Max-Planck-Inst.
Straße
Fe
d
Museen imGRASSI
Central-theater
SkalaHochschule fürMusik und Theater
Schulmuseum
BStU + Museum in der Runden Ecke
Antiken-museum
Mäd
ler-P
assa
ge
Messehofpassage
SpecksHof
CityHochhaus
MDR
Naturkunde-museum
ÄgyptischesMuseum
Auerbachs Keller
Zeitgeschicht-liches Forum
Musikschule
Kunstmuseumder Sparkasse
Peters-bogen
Bach-Archiv
Apotheken-museum
Universitäts-Campus-
Paulinum
Neues Augusteum,+Galerie
MensaamPark
Hörsaal-gebäude
Leibniz Forum
MoritzbasteiStadthaus
IHK
Feuer-wache
Mendelssohn-Haus
Praxisklinikam Johannisplatz
Löhrs Carré
Ev.-reformierte
Kirche
Stadt-bibl.
Lutherkirche
Amerik.Konsulat Polizei-
direktion
L d i htHGB
Galerie f. zeitgen. Kunst
Augustusplatz(in Bau)
Pete
rs-
stei
nweg
Gewandhaus
Oper
Haus desBuches
Erich
-Wein
ert-Straß
e
NeuesRathaus
AltesRathaus
Bundesverw.-gericht
MdbK
Löhr
str.
Lumumba-
Zum ArabischenCoffeebaum
Stadtge-schichtl.Museum
Paul-Gerhardt-Weg
Leibnizweg
Käthe-
Prellerstraß
e
Fritz-
Seger-Str.
Richter-
Erfurter-Straße
Mencke-
str.
Berggartenstraße
Marbachstr.
Schillerweg
Plat
nerstr.
Winkelstr.
3 2 1
Poeten-Menckestraße weg
Schlöß
chen
wg.
Turm
-gu
tstr.
gstr.
GohliserSchlösschen
Villa Ida
Schiller-haus
Bre
itenf
elde
r
Str.
cher
aße
Nat
onek
-st
raße
Magdeburger Straße
ritzs
cher
Str.
Sto
ckst
r.
Blumen- straße
Kanals
tr.str
aße
Mechler-
str.
Erlenstr.
Blochmannstr.
Lützo
w-
Auerbach-platz
Blumen- str.
Regi
nens
tr.
Sass
traße
Daumierstraße
Benedixstraße
Blochm.-str.
Freiligrathplatz
M.-Metzger-Str.
Gohlis-Arkaden
The- resien-
straßePetzscher Str.Hartz- straßeDes
saue
r Stra
ße
Anha
lter
Str.
Bernbg.
Straße
Ham
burger Straße
Mag
dale
nens
tr.
SchiebestraßeSchönefelder
Straße
Geibels
traße
Hambg. Str.
Gedikestraße
4Kleis
t-
Kunadstr.
Wilhelminenstr.
Rückert Str.W.-Sammet-
Straße
Schinkel-str.
Witt
enbe
rger
Stra
ße
Salzmannstr.
Berlin
er S
traße
1
Am Flügelrad Diesel-
straße
2
Heinickestraße3Dinterstr.
Mörike-str.
Coppistr.straße
str.
Lenau Str.
Dinter-
straße
Wolfener Straße Schorlem-
mer Straße
Friedensstr.
thal
er
S
traße
Lütz
owst
r.
EisenacherGothaer StraßeStraße
Georg-Schu-
mann-
Bleichert-
Straße
Delitz
sche
r Str.
Blumenstr.
Böhme-
str.
Elsbeth- straße
Cöthner Straße
1 Endnerstraße2 Knauerstraße3 Lüderstraße
Cöthner Straße
Möckernsche Str. Lind
en-
Gohliser
straße
Trufanow-
Straße
Ehren-
stein-
straße
straße
Straße
Frickestraße
Kirch-platz
Ulrichst
r.
Preller-
Halberst.-Str.
Parth
e
Nordfriedhof
Alter
Israel.
Friedh.
Gohlis-Center
HTWK
Kleing. Hauschild
Zöllner-
Täubchenweg
Simon-Dubnow-Institut
HBFPromenadenOst
HBFPromenadenWest
Löhr sCarré
Brockhaus-zentrum
Commerz-bank
Forumam Brühl
IbisHotel
Augustus-platz Oper
Augustus-platz Gewandh.
Burg-platz
StädtischesKaufhaus
Karstadt-Warenhaus
Zentral-straße
Otto-Schill-Straße
Markt-galerie
H Tram
Wittenberger Str.
H Tram
Hamburger Str.
H Tram
Apelstr.
H Tram
baumstr.
H Tram
Menckestr.
H Tram
Nordplatz
H Tram
F.-Seger-Str.
H Tram G.-Schumann- /Lützowstr.
Str.
H Tram
S-Bhf.Gohlis
H Tram
G.-Schumann- /Lindenthaler Str.
S-Bhf. Coppiplatz
H Tram
Wilhelminenstr.
H Tram
Chausseehaus
H Tram
Winter-gartenstr.
H Tram
H Tram
HBFWestseite
HauptbahnhofLVB Infopoint
H Tram
Fr.-List-Platz
H Tram
Hofmeisterstr.
H Tram
Goerdelerring
H Tram
Leibnizstr.
H Tram
Lortzingstr.
H Tram
AugustusplatzH Tram
Johannispl.
H Tram
Gerichtsweg
H Tram
Gutenbergpl.
H Tram
W.-Leuschner-Platz
H Tram
Wächterstr.
H Tram
Neues Rathaus
H Tram
Thomaskirche
H Tram
Westplatz
H Tram
Roßplatz
H Tram
Gottschedstr.
H Tram
H Tram
H Tram
Mitte
Gohlis-Mitte
Gohlis-Süd
GOHLIS
0 1 km200 m 300 m 600 m 800 m
Neue Messe Leipzig
10.2
011
© W
WW
.ATE
LIE
R-K
IRC
HH
OF.
DE
Höfe am Brühl(in Bau)
84 World Conference on Regenerative Medicine, November 2–4, 2011
Anzeige
Neurosymposium 2012
TOPICSNeuroregeneration, plasticity and rehabilitationWhat embryogenesis can teach us about regenerationImaging and novel diagnosticsNeurodegeneration in stroke, Alzheimer dementia, and agingVascular aspects of neurodegenerationBalancing immune responses in neurodegenerationThe Janus Face of reactive astrogliosisMitochondria as cellular targets for neuroprotectionSupporting lesioned and aging brains – future perspectivesStem cell therapies for strokeHot news on successful therapeutic translations
May 2–5, 2012 | Potsdam, GermanyTHE MAGDEBURG MEETING SERIES
7th International Symposium on
neurorepair-2012.deCONFERENCE COORDINATORS Johannes Boltze, Alexander Kranz, Daniel-Christoph WagnerFraunhofer Institute for Cell Therapy and Immunology, Leipzig Georg Reiser Otto-von-Guericke-Universität Magdeburg, Medizinische Fakultät, Institut für Neurobiochemie, MagdeburgKlaus Reymann Leibniz Institute for Neurobiology, Magdeburg
CONFERENCE OFFICEevent lab. GmbHDufourstr. 15D–04107 Leipzige-Mail: [email protected]: +49 341 24 05 96 -50fax: +49 341 24 05 96 -51
CONFERENCE VENUEKongresshotel Potsdamam Templiner Seeam Luftschiffhafen 1D–14471 Potsdam
www.wcrm-leipzig.com \\ 85
information
world conference on regenerative medicine [Germany | Leipzig | October 23–25, 2013]
www.wcrm-leipzig.com
we regeneration
next event 2013
Save the Date