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Venue:Campus Antonio MachadoUniversidad Internacional de AndalucíaPalacio de JabalquintoPlaza de Santa Cruz, s/n 23440 Baeza (Jaén), SpainTel: +34 953 74 27 75Fax: +34 953 74 29 75E-mail: [email protected]
Workshop coordinator:Joaquín TorreblancaUniversidad Internacional de Andalucí[email protected]
More information andapplication:http://www.unia.es/biomedicine
Current trends in Biomedicine
Workshops
PROTEASES AT WORK: CUES FOR UNDERSTANDING NEURAL DEVELOPMENT AND NEURODEGENERATION
SpeakersCarl P. Blobel. Arthritis and Tissue Degeneration Program, Hospital for Special Surgery / Departments of Medicine and of Physiology, Biophysics and Systems Biology, Weill Medical College of Cornell University. New York, NY, USA.
Paola Bovolenta. Centro de Biología Molecular “Severo Ochoa”, CSIC-UAM / CIBER de Enfermedades Raras (CIBERER). Madrid, Spain.
Elena Cattaneo. Department of Biosciences and Center for Stem Cell Research, Università degli Studi di Milano. Milan, Italy.
Bart De Strooper. KU Leuven Center for Human Genetics and Leuven research Institute for Neuroscience and Disease (LIND) / VIB Center for the Biology of Disease. Leuven, Belgium.
Monica Di Luca. Dipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano and Centre of Excellence on Neurodegenerative Diseases. Milan, Italy.
Kristina Endres. Department of Psychiatry and Psychotherapy, University Medical Center of the Johannes Gutenberg University Mainz. Mainz, Germany.
Pilar Esteve. Centro de Biología Molecular “Severo Ochoa”, CSIC-UAM / CIBER de Enfermedades Raras (CIBERER). Madrid, Spain.
Isabel Fariñas. Departamento de Biología Celular, Universidad de Valencia / Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED). Valencia, Spain.
Nigel M. Hooper. Institute of Brain, Behaviour and Mental Health, Faculty of Medical and Human Sciences, University of Manchester. Manchester, UK.
Leszek Kaczmarek. Department of Molecular and Cellular Neurobiology, The Nencki Institute of Experimental Biology. Warsaw, Poland.
Stefan F. Lichtenthaler. German Center for Neurodegenerative Diseases (DZNE) and Technical University Munich (TUM). Munich, Germany.
Lieve Moons. Laboratory of Neural Circuit Development and Regeneration, Animal Physiology and Neurobiology Section, Department of Biology, KU Leuven. Leuven, Belgium.
Paul Saftig. Institut für Biochemie, Christian-Albrechts-Universität zu Kiel. Kiel, Germany.
Sangram S. Sisodia. The Center for Molecular Neurobiology, University of Chicago. Chicago, IL, USA.
Organized by:Paola Bovolenta Centro de Biología Molecular “Severo Ochoa”, CSIC-UAM. Madrid, Spain.
Paul SaftigInstitut für Biochemie, Christian-Albrechts-Universität zu Kiel. Kiel, Germany.
Baeza, Spain • 20th-22nd October 2014Deadline: 5th September 2014
ScopeProteolytical processing of membrane bound molecules is emerging as a fundamental mechanism for controlling the strength and timing of cell-to-cell communication, which is at the basis of tissue development and homeostasis. This process acquires particular importance in the context of the brain because its function strongly depends on well- orchestrated interactions among many different cell types. Members of families of metalloproteinases are major effectors of these events. Understanding how proteinases, particularly metalloproteinases, coordinate brain development or how they contribute to brain pathologies when disregulated, requires multi-disciplinary approaches tackling the problem from different perspectives. This workshop will summarize the most recent biochemical and genetic evidence demonstrating that proteases are required for development, function and homeostasis of the CNS, underscoring their relevance in neurodegeneration and discussing whether endogenous or pharmacological modulation of their activity represents a therapeutic tool to prevent synaptic loss, neural defects or brain diseases.
Format of the WorkshopThe workshop will bring together 17 speakers and a maximum of 33-35 participants, to form a group of around 50 people. The scientific programme will start in the morning of Monday, October 20th and will end around noon on Wednesday, October 22nd. Ample time for informal discussion will be reserved. Participants will be invited to present a poster.
Venue of the WorkshopThe workshop will be held in Baeza, at the “Campus Antonio Machado”, a XVII century building turned into a Conference Centre of the Universidad Internacional de Andalucía (UNIA). This Seat includes a recently restored residence, where participants will be accommodated. Baeza is a World Historic Heritage town, renowned for its Renaissance and Gothic buildings.
Shanthini Sockanathan. The Solomon Snyder Department of Neuroscience, The Johns Hopkins University School of Medicine. Baltimore, MD, USA.
Rudolph E. Tanzi. Genetics and Aging Research Unit, MassGeneral Institute for Neurodegenerative Disease, Department of Neurology, Massachusetts General Hospital and Harvard Medical School. Charlestown, MA, USA.
Taisuke Tomita. Department of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo. Tokyo, Japan.
