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How to solve synthesisproblems
1 Working backwards fromthe product Recognizein the product clues about
the last reaction
study tip find a friend write
out reactions only show yourfriend the product and havethem guess the startingmaterial and reagent
Presumes you know the
roadmap
2 Count carbons in productsvs the starting material
Do you need to makeor break a C C bond
ftp.CHRXMakes
etrahaloalkanes
E O Oil it
1 SiazBH 2 Haqq Th C H R C Rnon Markovnikov
toi t f
k i se e HSS04,12504,1120
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3I
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r iN nxI BHS 2 702 1100
V of Yon.Markovnikov Syn
i piiiiiiii
s 8 o Eye
f
Eof a E
3membered ring
a E np S Te t na t
e on IEEE EtT t'ts er si
fM s o
jes u
1
G carbons G carbons
yppOH vicinal didIs Wao't sandditin
Alkane
FBI 91 2 tsgateBr
TLd EzNotChina
7 carbons T carbons
eats E ETERacemic
Alkane Alcohol Syn addition ofIt and OH OH on le substituted
127b
TDBH
4753 wastHalite
I 1743
V EZ 4Notchiral
7 carbons 7 carbons
ofIII nah't
L Kiki LianeRacemic
AlkaneHalohydrin
IBI fashome want it
Not or
chiral Gt3AsrLd
C C bonds must use
broken ozonolysis11 carbons 8 carbons
e t
Alkane 30 Aldehydebroke
112 940327GHz zS
Br no
say.EE xEYsE2d
Zaitsev
3 carbons8 carbon5 carbons Br NEGI
ra t mineI23 g G S L
Zz g
b 8
Alkene Holo Hee E alkene
d EE iEIt quaBr NHzBr Racer.ie
m
isrEEogruEsnsl
s iEYgx
u Sv2
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