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Winter/Spring 2019

Forewords from the Head Dear DoCS: Ok, it's my fault that this newsletter is a bit late. Justine tried to get me in line, but life has been a tad exciting. First my schedule got derailed by a new puppy being added to the house (and there will be no comments about "drunk adopting": it was just one glass of wine at the Saving Grace fundraiser that tipped that decision point). When Justine

reminded me again that the newsletter was supposed to be ready to go out, a trip to celebrate Swedish Midsummer and all those annual review visits seemed to get in the way. Then the mountains beckoned over the 4th and here we are. I loved visiting with each of you to find out what you have been doing. As always, you are a busy lot! We continue to grow, with 2 Research Assistant Professor positions recently approved. We wished Suzanne Kennedy-Stoskopf and Rich Redding happy retirements and the Dean decided it was time to make my phased retirement news formal. You are stuck with me as Dept Head until June 30, 2020, but after that I will continue to teach surgery and advocate for my adopted group (EAMS/Aquatic/Zoo/Wildlife). Someone needs to keep reminding the University what a treasure CMAST is! And yes, Craig, I'm working on my bad habit of referring to the "beach" instead of the "coast". We are also formally starting the NCSU Equine Program as Reedy Creek Farm comes online. Please welcome back Jori Vasgaard, who has been tasked with making CVM and CALS play nicely (anyone up for a joint barn painting session?). Practice Plan is looking a bit healthier due to your hard work this spring. A Huge THANK YOU! I hope you have some time to enjoy steamy NC this summer: the students will be back before you know it. --Lizette

_ _ _ _ _ _ _ _ _ _ Faculty & Staff Updates New Employees Dr. Megan Burke, Assistant Clinical Professor of Equine Emergency. Dr. Kara Walker, Assistant Research Professor of Behavioral Ecology

Faculty & Staff Updates Awards/Congratulations Grants Books & Papers In the News Postdoc, Graduate Student

& Resident News Personal News Who Am I Other News and Updates

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Dr. John Bonagura, Associate Clinical Professor of Cardiology Departing Faculty and Staff Judy Paps retired on January 1, 2019. Archana Sharma – March 1, 2019. Dr. Suzanne Kennedy-Stoskopf retired on July 1, 2019. Dr. Rich Redding retired on July 1, 2019.

Faculty Recruitment Updates Dr. Hepworth-Warren started as the Assistant Clinical Professor of Equine Internal Medicine on

June 27, 2019. Dr. Tal Ben-Horin has been hired as the Assistant Professor of Shellfish Pathology and is starting

on July 15, 2019. Dr. Sarah Townsend has been hired as an Assistant Professor in Small Animal Soft Tissue and

Oncologic Surgery and is starting on August 29, 2019. We are currently in negotiations with the final candidates for the Equine Orthopedic Surgery and

Emergency Critical Care positions. We are in the process of recruiting for faculty positions in Small Animal General Practice, Exotics,

and Equine Internal Medicine. We have postponed the searches for Dentistry and Dermatology. Dentistry will reopen in

September 2019 and Dermatology will reopen in January 2020. _ _ _ _ _ _ _ _ _

Awards/Congratulations (December 2018 – May 2019) Dr. Liara Gonzalez was reappointed to 2nd term Assistant Professor of Gastroenterology and Equine Surgery. Dr. Tara Harrison was reappointed to 2nd Term Assistant Professor of Exotic Animal Medicine. Dr. April Kedrowicz was promoted to Associate Professor with tenure in Communication Education. Dr. Duncan Lascelles has been named a Fellow of the Royal College of Veterinary Surgeons. Fellowship is the highest status Membership of the College. Dr. Lascelles will receive the award at the RCVS Fellowship Day in September 2019. Dr. Greg Lewbart received the 2019 Huffman Leadership Award. Dr. Sara Lyle received tenure. Dr. Freya Mowat was reappointed to 2nd Term Assistant Professor in Ophthalmology.

Dr. Sarah Musulin was promoted to Associate Clinical Professor of Emergency Critical Care. Dr. Ken Royal was promoted to Associate Professor with tenure in Educational Assessment and Outcomes. Dr. Lauren Schnabel was promoted to Associate Professor with tenure in Equine Orthopedic Surgery. Dr. Lauren Schnabel was named an NC State University Faculty Scholar. Dr. Brenda Stevens was promoted to Clinical Professor of General Practice. Dr. Sandy Tou received the Annabelle Coat of Excellence. Dr. Marine Traverson’s Cementoplasty Study was awarded $25,000. The funds were donated by Andy’s Army through the CMI Foundation Account. Dr. Hans Westermeyer was reappointed to 2nd Term Assistant Professor in Ophthalmology.

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Dr. Hiroto Yoshikawa was reappointed to 2nd Term Assistant Professor in Radiation Oncology.

_ _ _ _ _ _ _ _ _ _ Grants Received (December 2018 – May 2019) Blikslager AT, Odle J, Van Landeghem L. Bioactive nutrients enhance intestinal neural networks and rescue mucosal repair in developing neonates. USDA-AFRI, 2019-2022, $500,000. Duffy DJ (PI), Fisher M. Effect of increasing the bite depth of an epitendinous suture on the biomechanical strength of canine tendon repairs in a canine cadaveric translational laceration model. CVM Research Committee intramural grant $10,500. Eby A, Duffy DJ (PI) Effect of barbed epitendinous suture in combination with a core locking loop pattern for flexor tendon repair in a translational canine cadaveric model. Firestone VPP Grant, $3,000. Gonzalez LM (PI). The Effects of Storage Method on Intestinal Allograft Immune Profile and Viability, DOD, 2019 (2YR, $1.5M). Gonzalez LM (PI). Modulation of Reserve Stem Cells in Regeneration of Ischemic-injured intestine, NIH (ORIP, 1R03OD026598-01), 2018 (2YR, $114,000). Hare B (PI), Gruen M (PI). Longitudinal Cognitive and Emotional Development in Working Dogs. NIH. 5YR, $1.9M. Sheats MK (PI), Kedrowicz AA (Co-I). Investigating the Impact of a Printed Telephone Communication Guide on Clinical Year Veterinary Student Telephone Communication Skills. CVM Intramural Grant. 2019, $9275. Lewbart GA (PI). Tourist-Induced Stress in Seabirds in Ecuador. NC State-CVM Global Health Travel Award, 2019, $3,000. Mowat FM, White A (DVM Class of 2022). Genetic Characterization of a Hereditary Choriortinopathy in the Red Wolf (Canis Rufus),

Triangle Community Foundation. $5,000. Summer 2019, Summer research funding for Anne White, DVM student mentee. Mowat FM, Cousins S, McGahn MC. Responses of the macula to toxicant injury: the role of PGC1 a isoforms in photoreceptor neuroprotection. NIH/NEI $638,590. 3/2019 – 2/2023. Mowat FM, Matthew B, Kennedy-Stoskopf S. Elimination of an Inherited Form of Blindness in the Endangered American Red Wolf (Canis Rufus). Sarah De Coizart TENTH Perpetual Charitable Trust. $65,000. 1/29/18-1/2/19. Vadum Inc PR, Olby NJ (PI) for subcontract with NCSU. Working Dog Hearing Protection /Active Communication System. Funded by DOD for $19,461. Nolan, Van Landeghem (PIs), Dekaney, Ghashghaei, Cheng, Schnabel, Ivanisevic, Zarahoff (Co-Is). Acquisition of an X-rad 320 Xl X-ray irradiator for cell and small animal research. NC Biotechnology Center. 2019-2019; $149,868. Schnabel, Fowler (PIs). The genetic determinants of Staphylococcus aureus osteoarticular metastasis. Triangle Center for Evolutionary Medicine. PIs: Schnabel, Fowler. 2019-2019; $12,000. Diekman, Schnabel (PIs). Senolytic therapy in an equine model of post-traumatic osteoarthritis. UNC/NC State (NC TraCS) Translational Research Matched Pilot Grant Program. 2019-2020; $50,000. Eward W, Traverson M. Percutaneous cementoplasty of canine appendicular osteosarcoma and neoadjuvant radiation therapy as model for palliative management of human long bone metastasis. C3O, 2019-2020, $99,914.

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Abstracts, Books, Papers Published and Accomplishments (December 2018 – May 2019) Gonzalez LM, Stieler Stewart A, Freund J, Renee Kucera C, Dekaney CM, Magness ST, Blikslager AT. Preservation of reserve intestinal epithelial stem cells following severe ischemic injury. Am J Physiol Gastrointest Liver Physiol. 2019, Epub ahead of print, Selected as an APS Select Article – Identified as one of the best published articles in physiologic research, April 2019. Manship AJ, Blikslager AT, Elfenbein JR. Disease features of equine coronavirus and enteric salmonellosis are similar in horses. J Vet Intern Med. 2019;33:912-917. Blikslager AT. Colic Prevention to Avoid Colic Surgery: A Surgeon's Perspective. J Equine Vet Sci. 2019 May;76:1-5. Duffy DJ, Cocca CJ, Kersh ME, Kim W, Moore GE , Effect of bite distance of an epitendinous suture from the repair site on the the tensile strength tendon constructs in canine cadavers. Accepted April 23, 2019. Am J Vet Res R No. 19-02-0011R1. Accepted for podium presentation ECVS Budapest, Hungary July 2019. Role: Duffy- corresponding author. Cocca CJ, Duffy DJ, Kersh ME, Kim W, Groenewold A, Moore GE. Biomechanical comparison of three epitendinous suture patterns as adjuncts to a core locking loop suture for repair of canine flexor tendon injuries. Veterinary Surgery. 2019;1–8. https://doi.org/10.1111/vsu.13266. Role: Duffy- corresponding author. Duffy DJ, Kindra CG, Moore GE. Comparison of initial leak pressures after single- and double-layer cystotomy closure with barbed and nonbarbed monofilament suture material in an ex vivo ovine model. Vet Surg. 2019 Apr;48(3):424-430. Presented at ACVS Surgery Summit Phoenix October 2018. Role: Duffy- corresponding author.

Duffy DJ, Duddy HR, Keating S, Gutierrez-Nibeyro SD. Influence of barbed suture on leak pressures after double-layer inverting closure of cystotomy sites in sheep. Vet Surg. 2018 Dec;47(7):902-907. doi: 10.1111/vsu.12935. Epub 2018 Dec. Presented at ACVS Surgery Summit Phoenix Arizona October 2018. Role: Duffy- corresponding author. Putterman AB, Duffy DJ, Kersh ME, Rahman H, Moore GE. Effect of a continuous epitendinous suture as adjunct to three loop pulley and locking-loop patterns for flexor tendon repair in a canine model. Veterinary Surgery. 2019;1– 8. https://doi.org/10.1111/vsu.13268. Presented as podium presentation at ACVS Surgery Summit Phoenix October 2018 and Veterinary Orthopedic Society Conference, Breckenridge Colorado 2018. Role: Duffy- corresponding author. Schlag AN, Hayes GM, Taylor AQ, Kerwin SC, Dugat DR, Vitt MA, Stratton DT, Duffy DJ. Analysis of outcomes following treatment of craniodorsal hip luxation with closed reduction and Ehmer sling application in dogs. J Am Vet Med Assoc. 2019 Jun 15;254(12):1436-1440. Presented at ECVS Surgery Summit Athens Greece 2018. Role: Duffy- Co-PI. Rosser MF, Wycislo KL, Duffy DJ, Vieson MD. What is your diagnosis? A ventral cervical mass in a dog. Vet Clin Pathol. 2019 Mar;48(1):125-127. Role: Duffy- PI. Cray MT, Selmic LE, McConnell BM, Lamoureux LM, Duffy DJ, Harper TA, Philips H, Hague DW, Foss KD. Effect of implementation of a surgical safety checklist on perioperative and postoperative complications at an academic institution in North America. Vet Surg. 2018 Dec;47(8):1052-1065. Chu KL, Duffy DJ, Vieson ME, Moore GE. Ex-vivo comparison of leakage pressures and leakage location using a novel technique for creation of functional side-to-side canine small intestinal anastomoses." Accepted to Veterinary Surgery February 2019. Manuscript ID is VSU-19-037.R1 Accepted for podium presentation ECVS Budapest, Hungary July 2019. Role: Duffy- corresponding author.

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Corrie J, Phillips H, Engel DM, Vetter AM, Schmiedt C, Kendall A, Duffy DJ, Holt DE, Schaeffer DJ, Follette CM, Mayhew PD, Marks SL. Clinical findings, diagnostic test results, and treatment outcome in cats with hiatal hernia. Accepted to Journal of Veterinary Internal Medicine. Accepted Manuscript ID is JVIM-18-461.R1. Presented at ACVS Surgery Summit Phoenix October 2018. JK Reagan, C Fallon, B Sutton, S Lana, M Lafferty, WTN Culp, M Lafferty, J Liptak, DJ Duffy, MC Simons, S Boston, LE Selmic. Complications and Outcome Associated with Unilateral Thyroidectomy in Dogs (2003-2015): 156 Cases. Presented at ACVS Surgery Summit October 2016. Manuscript Accepted JAVMA-18-11-0552.R2. Schlein LJ, Connolly SL, Moran C, Duffy DJ. Pathology in Practice: Gossypiboma; clinical presentation and diagnostic evaluation in dogs. Manuscript Accepted JAVMA-18-04-0180. Role: Duffy- PI. Duffy DJ, Bennet AR. Soft Tissue Surgery in Hedgehogs. Chapter 20. Small Mammal: Soft Tissue Surgery in Exotics. Ed. Bennet and Pye. 2019. Submitted for print April 2019. Role: Duffy- primary author. Gonzalez LM. Intestinal Injury and Healing in the Horse. In: Smith B, Van Metre d, and Pusterla N, Eds., Large Animal Internal Medicine, 6th edition. Elsevier. Published June 26th, 2019. Archibald KE, Scott GN, Bailey KM, Harms CA. 2 019. 2-Phenoxyethanol (2-PE) and tricaine methanesulfonate (MS-222) immersion anesthesia of American horseshoe crabs (Limulus polyphemus). J Zoo Wildl Med 50: 96-106. doi.org/10.1638/2018-0085. Barratclough A, Tuxbury K, Hanel R, Stacy NI, Ruterbories L, Christiansen E, Harms CA. 2019. Baseline plasma thromboelastography in Kemp’s ridley (Lepidochelys kempii), green (Chelonia mydas) and loggerhead (Caretta caretta) sea turtles and its use to diagnose coagulopathies in cold-stunned Kemp’s ridley and green sea turtles. J Zoo Wildl Med 50: 62-68. doi.org/10.1638/2018-0142.

Westermeyer HD, Cook AG, Harms C, Boylan S. 2019. Phacoemulsification cataract surgery in the loggerhead turtle (Caretta caretta): surgical technique and outcomes in 10 cases. Vet Ophthalmol, DOI: 10.1111/vop.12635. Mikles, CS, Harms CA, Buckel JA, Rudershausen PJ. 2019. Examining the severity of roof-hooking injuries in dolphinfish: a comparison between computed tomography and gross necropsy. N Am J Fish Manage, doi.org/10.1002/nafm.10252. Mason SE, Papich MG, Schmale M, Harms CA, Davis AS. 2019. Enrofloxacin pharmacokinetics and sampling techniques in California sea hare (Aplysia sp.). J Am Assoc Lab Anim Sci, DOI: 10.30802/AALAS-JAALAS-18-000072. Cauture F, Sterba-Boatwright B, Rocho-Levine J, Harms CA, Miedler S, Fahlman A. Using respiratory sinus arrhythmia to estimate inspired tidal volume in bottlenose dolphin (Tursiops truncatus). Frontiers Phys 10:128. doi: 10.3389/fphys.2019.00128 Bembenek-Bailey SA, Niemuth JN, McClellan-Green PD, Godfrey MH, Harms CA, Gracz H, Stoskopf MK. 2019. NMR metabolomic analysis of skeletal muscle, heart and liver of hatchling loggerhead sea turtles (Caretta caretta) experimentally exposed to crude oil and/or Corexit. Metabolites 9:21, doi:10.3390/metabo9020021. Harms CA, Wyneken J. 2019. Husbandry and management of sea turtles in human care. In: Divers SJ, Stahl S, Mader DR (eds.). Mader’s Reptile Medicine and Surgery, 3rd ed. Elsevier, St. Louis, Chapter 24, pp. 180-193. Posner LP, Harms CA, Smith SA. Sedation, anesthesia, analgesia and euthanasia, In: Smith SA (ed). Fish Diseases and Medicine. CRC Press, Boca Raton, Florida. Chapter 18, pp. 283-304. Hanley AA, Kedrowicz AA, Hammond S, Hardy EM. (2019). The impact of team communication training on students’ behaviors, perceptions, and team functioning during an introductory surgery course. Journal of

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Veterinary Medical Education, 46(1), 45-55. Role: Kedrowicz-Corresponding author. Sheats MK, Hammond S, Kedrowicz AA. (2018). Analysis of 4th year veterinary students’ telephone communication skills at a veterinary teaching hospital. Veterinary Sciences, 5(4), 99. Role: Kedrowicz- Corresponding author. Sheats MK, Royal K, Kedrowicz AA. (2018). Using readability software to enhance the health literacy of equine veterinary clients: An analysis of 17 AAEP “Newsletter and Website” articles. Equine Veterinary Journal. [Epub ahead of print]. Lewbart GA, Lewbart DT. 2019. Laws and Regulations: Americas. In: Mader’s Reptile & Amphibian Medicine and Surgery (3rd ed.), Divers S, Stahl S (eds). Elsevier Publishing, 1456-1463. Petritz OA, Westermeyer HD, Whitehead MC, Christiansen EF, Lohmann KJ, Lohmann CMF, Lewbart GA. 2019. Effective mydriasis in juvenile loggerhead turtles (Caretta caretta) following topical administration of rocuronium bromide and 10% phenylephrine. J Vet Ophth DOI: 10.1111/vop.12681 Cerreta A, Vaden SL, Lewbart GA, Muñoz-Pérez JP, Páez-Rosas D. 2019. Increased BUN and glucose in a group of San Cristóbal Galapagos tortoises (Chelonoidis chathamensis). Vet Rec Case Report 7:3000699. Doi:10.1136/vetreccr-2018-000699 Whitehead M, Vanetten CL, Zheng Y, Lewbart GA. 2019. Hematological parameters in largemouth bass (Micropterus salmoides) with formalin-preservation: comparison between wild tournament-caught and captive-raised fish. PeerJ DOI 10.7717/peerj.6669 Dornburg A, Lamb AD, Warren D, Watkins-Colwell GJ, Lewbart GA, Flowers J. 2019. Are geckos paratenic hosts for Caribbean Island Acanthocephalans? Evidence from Gonatodes antillensis and a review of squamate reptiles acting as transport host. Bull Peabody Mus Nat Hist 60(1):55-79. Valle CA, Grijalva CJ, Calle PP, Muñoz-Pérez JP, Quezada G, Vera CA, Lewbart GA. 2019.

Methods of body temperature assessment in Conolophus subcristatus, Conolophus pallidus (Galápagos land iguanas), and Amblyrhynchus cristatus X C. subcristatus hybrid. PeerJ 7:e6291 DOI 10.7717/peerj.629 Adamovicz L, Griffioen J, Cerreta A, Allender MC, Lewbart GA. 2019. Tissue enzyme activities in free-living eastern box turtles (Terrapene carolina carolina). J Zoo Wild Med. 50(1):45-54. Lynch AM, Ruterbories L, Griffith E, Hanel RM, Stablein AP, Brooks MB. Evaluation of a panel of coagulation assays for monitoring the anticoagulant effects of rivaroxaban in healthy dogs. J Vet Emerg Crit Care 2019. Lynch AM, Ruterbories L, Griffith E, Hanel RM, Stablein AP, Brooks MB. The influence of feeding and gastroprotectant medications on the Factory Xa inhibitory activity of orally administered rivaroxaban in normal dogs. J Vet Emerg Crit Care 2019. Lynch AM, Ruterbories L, Jack J, Motsinger-Reif A, Hanel RM. The influence of packed cell volume versus plasma protein on thromboelastographic variables in a canine model. J Vet Emerg Crit Care Sharp CR, de Laforcade AM, Koengishof A, Lynch AM, Thomason JM. Consensus on the Rational Use of Antithrombotics in Veterinary Critical Care (CURATIVE): Domain 4 – Refining and monitoring antithrombotic therapies. J Vet Emerg Crit Care 2019; 29(1):75-87. Blais MC, Bianco D, Goggs R, Lynch AM, Palmer L, Ralph A, Sharp CR. Consensus on the Rational Use of Antithrombotics in Veterinary Critical Care (CURATIVE): Domain 3 – Defining antithrombotic protocols (dose, frequency, route, complications) for use in dogs and cats at risk of thrombosis. J Vet Emerg Crit Care 2019; 29(1):60-74 DeLaforcade AM, Bacek L, Blais MC, Goggs R, Lynch AM. Consensus on the Rational Use of Antithrombotics in Veterinary Critical Care (CURATIVE): Domain 1 – Defining populations at risk. J Vet Emerg Crit Care 2019; 29(1):37-48.

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Maggi RG, Kramer F. 2019. A review on the occurrence of companion vector-borne diseases in pet animals in Latin America. P&V.12:145. doi: 10.1186/s13071-019-3407-x. Breitschwerdt EB, Greenberg R, Maggi RG, Mozayeni BR, Lewis A, Bradley JM. 2019. Bartonella henselae bloodstream infection in a boy with pediatric acute-onset neuropsychiatric syndrome. J Cent Nerv Syst Dis. 11:1179573519832014. Breitschwerdt EB, Maggi RG. 2019. Bartonella quintana and Bartonella vinsonii subsp. vinsonii bloodstream co-infection in a girl from North Carolina. Med Microbiol Immunol. 208:101-107. Breitschwerdt EB, Maggi RG, Quach-Thanh C, Bradley JM. 2019. Bartonella spp. Bloodstream infection in a Canadian family. Vector-Borne and Zoonotic Diseases. 4:234-241. Maggi RG, Toliver M, Richardson T, Mather T, Breitschwerdt EB. 2018. Regional prevalences of Borrelia burgdorferi, Borrelia bissettiae, and Bartonella henselae in Ixodes affinis, Ixodes pacificus and Ixodes scapularis in the USA. Ticks Tick Borne Dis. 10:360-364. Westmoreland LSH, Stoskopf MK, Sheppard E, DePerno CS, Gould NP, Olfenbuttel C, Maggi RG. 2019. Detection and prevalence of Babesia spp. in American black bears (Ursus americanus) from Eastern and Western North Carolina. JWD. 10.7589/2018-06-164. Mozayeni BR, Maggi RG, Bradley JM, Breitschwerdt EB. 2018. Rheumatological presentation of Bartonella koehlerae and Bartonella henselae bacteremias: A case report. Medicine (Baltimore). 97:17. Maggi RG. Stealth pathogens. First European Crypto-Infections Conference: The Science behind Lyme Disease and other co-infectons. Dublin, Ireland. May 2019 Maggi RG. Métodos Serológicos y Moleculares para el Diagnóstico de Enfermedades Vectoriales (Spanish). First post-graduate course series. Universidad Nacional de Rosario; Facultad de Ciencias Veterinarias;

Secretaría de Estudios de Posgrado y Educación Continua. Santa Fe. Argentina. April 2019. Maggi RG. Review on the occurrence of companion vector-borne diseases in pet animals in Latin America. CVBD 14th Global Forum. Trieste, Italy. March 2019. Mowat FM, Wise E, Oh A, Foster ML, Kremers J. In vivo electroretinographic differentiation of rod, short-wavelength and long/medium-wavelength cone responses in dogs using silent substitution stimuli. Experimental Eye Research. 2019 May 22; doi: 10.1016/j.exer.2019.05.013 (Epub ahead of print). PMID: 31128103 Westermeyer HD, Royal KD, Druley G, Mowat FM. Use of a versatile, inexpensive ophthalmoscopy teaching model in veterinary medical student education results in increases in ophthalmoscopy proficiency. Journal of Veterinary Medical Education. 2019 Mar 28; doi: 10.3138/jvme.1117-157r. (Epub ahead of print) PMID: 30920947 Oh A, Foster ML, Williams JG, Zheng C, Ru H, Lunn KF, Mowat FM. Diagnostic utility of clinical and laboratory test parameters for differentiating between sudden acquired retinal degeneration syndrome and pituitary dependent hyperadrenocorticism in dogs. Veterinary Ophthalmology. 2019 Mar 12; doi:10.1111/vop.12661 (Epub ahead of print) PMID: 30864251 Westermeyer H, Salmon J, Baynes R, Yeatts J, Khattab A, Oh A, Mowat FM. Safety and efficacy of topically applied 0.5% and 1% pirfenidone in a canine model of subconjunctival fibrosis. Veterinary Ophthalmology, 2019 21(6):565-576. PMID: 29383824 Mowat FM, Avelino J, Bowyer A, Parslow V, Oh A, Foster ML, Bizikova P. Detection of serum antiretinal antibodies in dogs with SARDS using indirect immunofluorescence – a case-control study. European College of Veterinary Ophthalmologists Annual Conference, May 23-26th 2019, Antwerp, Belgium.

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Mowat FM, Foster ML, Jima D. Transcriptome of the canine macular RPE/choroid and retina: parallels with human macular gene expression. Association for Research in Vision and Ophthalmology Annual Conference, Vancouver BC, April 28th-May 2nd, 2019 Parslow V, Avelino J, Bowyer A, Oh A, Foster ML, Bizikova P, Mowat FM. Identification of circulating antiretinal antibodies in dogs with sudden acquired retinal degeneration syndrome using indirect immunofluorescence. Animal Science, Poultry Science, and Biochemistry Programs Research Day. April 25th 2019. *winner, 2nd place undergraduate student presentation Castillo A, Hodorovich D, Foster ML, Woychik R, Mowat FM. Characterizing the role of PGC1a transcripts and their effects on mitochondrial function and retinal aging. NC State Undergraduate Research Symposium April 24th 2019 *winner, undergraduate research award, Sigma XI Scientific Research Honor Society. Parslow V, Avelino J, Bowyer A, Oh A, Foster ML, Bizikova P, Mowat FM. Identification of circulating antiretinal antibodies in dogs with sudden acquired retinal degeneration syndrome using indirect immunofluorescence. NC State Undergraduate Research Symposium April 24th 2019 Castillo A, Hodorovich D, Foster ML, Woychik R, Mowat FM. Characterizing the role of PGC1a transcripts and their effects on mitochondrial function and retinal aging. Triangle Society for Neuroscience annual conference, April 4th 2019. *winner, best undergraduate poster presentation Mowat FM, Foster ML, Xu F, Loyoza O, Santos J, Woychik R. The role of a neuronal expressed fusion transcript of PGC1a in premature aging of retinal photoreceptors. Gordon Research Conference Mitochondrial Dynamics and Signaling, March 17-22nd 2019, Ventura CA. Lau J, Nettiffee J, Early P, Mariani C, Olby NJ, Munana K. Clinical characteristics, breed differences and quality of life in North American

dogs with acute steroid-responsive meningitis-arteritis. JVIM. May 2019. Accepted. Lewis MJ, Williams KD, Langley T, Jarvis L, Sawicki GS, Olby NJ. Development of a novel gait analysis tool measuring center of pressure for evaluation of canine chronic thoracolumbar spinal cord injury. J Neurotrauma 2019 Jun 6. doi: 10.1089/neu.2019.6479. [Epub ahead of print]. Role: Olby- senior author. Agler CS, Friedenberg S, Olivry T, Meurs KM, Olby NJ. Genome-wide Association Analysis in West Highland White Terriers with Atopic Dermatitis Vet Immunol Immunopathol. 2019; 209:1 – 6. Role: Olby- senior author. Meurs KM, Friedenberg SG, Olby NJ, Condit J, Weidman J, Rosenthal S, Shelton GD. A QIL1 Variant Associated with Ventricular Arrhythmias and Sudden Cardiac Death in the Juvenile Rhodesian Ridgeback Dog. Genes (Basel). 2019 Feb 21;10(2). pii: E168. doi: 10.3390/genes10020168. Yost O, Friedenberg SG, Jesty SA, Olby NJ, Meurs KM. The R9H phospholamban mutation is associated with highly penetrant dilated cardiomyopathy and sudden death in a spontaneous canine model. Gene. 2019 Feb 19;697:118-122. doi: 10.1016/j.gene.2019.02.022. [Epub ahead of print]. Olby NJ, Lim JH, Wagner N, Zidan N, Early PJ, Mariani CL, Muñana KR, Laber E. Time course and prognostic value of serum GFAP, pNFH, and S100β concentrations in dogs with complete spinal cord injury because of intervertebral disc extrusion. J Vet Intern Med. 2019 Mar;33(2):726-734. doi: 10.1111/jvim.15439. Epub 2019 Feb 13. Role: Olby- senior author. Sparks CR, Robertson I, Olby NJ. Morphometric analysis of spinal cord termination in Cavalier King Charles Spaniels. J Vet Intern Med. J Vet Intern Med. 2019 Mar;33(2):717-725. doi: 10.1111/jvim.15437. Epub 2019 Feb 13. Role: Olby- senior author. Meurs KM, Friedenberg SG, Kolb J, Saripalli C, Tonino P, Woodruff K, Olby NJ, Keene BW, Adin DB, Yost OL, DeFrancesco TC, Lahmers

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S, Tou S, Shelton GD, Granzier H. A missense variant in the titin gene in Doberman pinscher dogs with familial dilated cardiomyopathy and sudden cardiac death. Hum Genet. 2019 Feb 4. doi: 10.1007/s00439-019-01973-2. [Epub ahead of print]. Smith DR, Gaunt PS, Plummer PJ, Cervantes HM, Davies P, Fajt VR, Frey E, Jay-Russell MT, Lehenbauer TW, Papich MG, Parker TM, Phipps EC, Scheftel JM, Schnabel LV, Singer RS, Whaley JE, Wishnie JK, Wright LR, Costin M. The AVMA's definitions of antimicrobial uses for prevention, control, and treatment of disease. J am Vet Med Assoc 2019; 254(7):792-797 Davis (Sherman) AB, Schnabel LV, Gilger BC. Subconjunctival bone marrow-derived mesenchymal stem cell therapy as a novel treatment alternative for equine immune-mediated keratitis: a case series. Vet Ophthalmol 2019; Feb 4. doi: 10.1111/vop.12641. Epub ahead of print. Niemuth JN, Harms CA, MK Stoskopf. Sea turtle tears: a novel, minimally invasive sampling method for 1H-NMR metabolomics investigations with cold stun syndrome as a case study. Journal of Wildlife Diseases. 2019;in press. Yoshikawa H, Sunada S, Hirakawa H, Fujimori A, Elmegerhi S, Leary D, Kato T. Radiobiological characterization of canine malignant melanoma cell lines with different types of ionizing radiation and efficacy evaluation with cytotoxic agents. Int. J. Mol. Sci., 20(4); 841, 2019. Sweet KA, Nolan MW, Yoshikawa H (corresponding author), Gieger TL. Stereotactic radiation therapy for canine multilobular osteochondrosarcoma: 8 cases. Veterinary and Comparative Oncology, 2019 Apr 15. doi: 10.1111/vco.12481. [Epub ahead of print]. Yoshikawa H. Dosimetric assessment of reduction of gross tumor volume by two radiation delivery techniques identifies dosimetric changes to organs at risk. Veterinary Radiology and Ultrasound, in print.

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In the News Dr. Ed Breitschwerdt discusses the ever-fascinating bacteria Bartonella in the NC State podcast. Dr. Callie Fogle Research Connection. Dr. Brian Gilger Research Connection. A stem cell therapy first used in a study by Drs. Brian Gilger and Lauren Schnabel shows strong promise in treating a chronic equine eye disease. How do pets show love? Dr. Margaret Gruen counts the ways. Dr. Margaret Gruen Research Connection. Dr. Steve Marks talks with WRAL about what to do if your pet is bitten by a snake. Dr. Freya Mowat earns NIH career grant for innovative eye research. A study led by Dr. Kate Meurs has identified a gene associated with a common cause of heart disease in Dobermans, which would lead to new therapies for dogs and humans. Dr. Amy Snyder, Amanda Bates and Andrew Rotz launch PawCast, a podcast with advice on career development, personal finance and veterinary business skills. Study co-authors Drs. Brenda Stevens and Ken Royal discuss using salivary science to measure student stress during surgery training. Dr. Brenda Stevens talks with ABC 11 about what pet owners should know about CBD products. Dr. Marine Traverson Research Connection. Clinical study from Drs. Matthew Breen, Shelly Vaden and Claire Wiley to test innovative cancer detection tool, seeks participants. What is it like to give polar bear anesthesia for 8 hours? Dr. Alessio Vigani is on the few veterinarians who know.

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Cataract surgery performed by Dr. Hans Westermeyer restores vision for two beloved pet rabbits. Dr. Hans Westermeyer discusses launching a study identifying anatomical features that predict when a glaucoma attack will occur.

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Staff, Post-doc, Graduate Student & Resident News Dr. Nanelle Barash, Internal Medicine Resident, received the Honeycutt Coat of Excellence. Dr. Alix Berglund was awarded an AAI Careers in Immunology Fellowship. Dr. Kaori Davis won the best abstract prize for her oral abstract presentation at the European Academy of Allergy and Clinical Immunology Annual Congress. Dr. Lauren Green, Neurology Resident, received the Cooper Aikin Coat of Excellence. Hedgpeth M. (2019, January). Multiple-choice questions: Do yours make the cut? Session presented to the Eshelman School of Pharmacy faculty at the University of North Carolina, Chapel Hill, NC. Hedgpeth M. (2019, May). Multiple-choice questions: Do yours make the cut? A hands-on workship for the Eshelman School of Pharmacy's Center for Innovative Pharmacy Education & Research at the University of North Carolina, Chapel Hill, NC. Julie Nettifee was the recipient of the Earl Rippie Veterinary Nurse Scholarship through NAVC in January 2019. In March, Laura Ruterbories’ Veterinary Technician Specialist application in Laboratory Animal Medicine was accepted by the ALAVTN-- one of just two in the country for the 2018 application year. She is the first and currently only registered veterinary technician in North Carolina to pursue this specialty!

Alicia Schubert from the Schnabel Lab was awarded the Richard L Blanton Outstanding Capstone Award 2019. Alicia Schubert from the Schnabel Lab won 1st place at the NC State University CALS Undergraduate Research Day Competition 2019. Alicia Schubert from the Schnabel Lab was awarded outstanding poster at the Undergraduate Research Symposium, Spring 2019. Dr. Amy Stewart, PhD Candidate, received the Boehringer Ingelheim Veterinary Graduate Award. Dr. Amy Stewart, PhD Candidate, also received the Monica Menard Memorial Award for Excellence in Veterinary Pathobiology Research. Dr. Amy Stewart, PhD Candidate, also received the AAEP Past Presidents’ Research Fellow Award. Sara Tuft, Veterinary Student, AVMA/AVMF proposal selected for competition. Dr. Amanda Zielger presents her findings on how firocoxib can help equine colic patients.

_ _ _ _ _ _ _ _ _ _ Personal News

Eva and Jay Cook welcomed baby boy Wilkins Paul on March 8th!

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Kent and Danielle Passingham welcomed baby boy Hayden on May 17th!

Drs. Stephanie Williams and Andy Stringer welcomed baby boy Henry Arthur Stringer on Valentine’s Day!

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Who Am I Dr. John Bonagura, Associate Clinical Professor of Cardiology John Bonagura, DVM, DACVIM (Cardiology, Internal Medicine) is Professor Emeritus of Veterinary Clinical Sciences at the Ohio State University College of Veterinary Medicine, where he has spent the majority of his career. Dr. Bonagura has been Visiting Research Fellow at the University of Edinburgh and served as Gilbreath-McLorn Endowed Professor of Veterinary Cardiology at the University of Missouri from 1996 through 2001 before returning to Ohio State. His research interests include echocardiography and his clinical cardiologic interests extend across species. Dr. Bonagura is a native North Carolinian who was raised in New Jersey and has spent most of his life residing in Columbus Ohio. He is excited about coming to Raleigh and is looking forward to working with faculty, staff and students at the NC State College of Veterinary Medicine. Dr. Bonagura enjoys skiing, board sailing, and travel.

Dr. Megan Burke, Assistant Clinical Professor of Equine Emergency She transitioned from her Clinical Veterinarian position to her new role!

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Dr. Kara Walker, Assistant Research Professor of Behavioral Ecology Dr. Walker completed her undergraduate degree in Animal Behavior at Bucknell University and her Ph.D. in Evolutionary Anthropology at Duke University. Following graduation she continued on as a post-doctoral researcher at Duke and became a Lecturer in the Department of Anthropology at NCSU until coming to the CVM. Her research specialty is in behavior and ecology of mammals and her doctoral and post-doctoral work focused on understanding sociality in female chimpanzees at Gombe National Park, Tanzania. When Dr. Walker is not at work, she enjoys hiking, reading and traveling to far-flung places. She shares her home with her husband, Chris, son Bennett (3.5 years) and daughter, Madeleine (18 months).

_ _ _ _ _ _ _ _ _ _ Other News and Updates Drs. Clarke Atkins and Bruce Keene discuss the impact of the Jane Lewis Seaks Distinguished Professorship in Companion Animal Medicine. Two research projects with CVM authors among those cited as the most innovative equine studies of past year. Dr. Sathya Chinnadurai, former Zoological Medicine and Anesthesia resident at NCSU CVM accepted the position of Director of Animal Health at the St. Louis Zoo. ezyVet has been selected as the core program for the VH’s electronic medical record and hospital information system. UNC-TV visits the Turtle Rescue Team for an inside look at rehabilitation efforts.

Dr. Kyle Mathews celebrated a big birthday this year!

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Justine Tillerson, Newsletter Editor

Next Issue: Summer/Fall 2019