SIGNS & SYMPTOMSof WILMS TUMOR

BODY SYSTEM SIGNS & SYMPTOMS RATIONALE

Endocrine System

FeverCannot stimulate kidney for the production of erythropoetin

Lymphatic System

Decrease production of RBC in the bone marrow

Digestive System

Loss of appetiteConstipationNausea and vomiting

Urinary System

HematuriaIschemiaGU defects

Reproductive System

GU defects

Muscular System

Muscle weakness

Nervous System

LethargyDecrease level of consciousness

Respiratory System

Pulmonary edemaDsypnea

Cardiovascular System

High blood pressure

Integumentary System

Itching Pallor EdemaPruritus

Hematologic System

AnemiaUremia

Skeletal System

Pain at the joint

Endocrine System

> fever> cannot stimulate the kidney for the production of erythropoietin

> unknown reason> due to the kidney cannot perform its function well

Lymphatic System

> decrease production of RBC in the bone marrow

> ascites

> due to the decrease or absence of erythropoietin hormone which helps the bone marrow in the production of RBC> accumulation of fluid in the peritoneal cavity due to excessive fluid in the body

Digestive System

> loss of appetite

> constipation

> nausea and vomiting

> because any fever may cause temporary loss of appetite and all the nutrient that suppose to be for the body is being eaten by the tumor cells> due to infants who are still exclusively breastfed may go 7 days without a stool (for infant patients) and also due to the fluid imbalance in the digestive system> due to uremia the body compensate by excreting the toxins through vomiting

Urinary System > hematuria (blood in the urine)> ischemia

> GU defects (in terms of excretory)

> indicates that blood has passed through the tubule> due to its increasing tumor cells, compressing the surrounding tissue> due to blockage of tumor cells in the urine way the urine output decreases

Reproductive System

> GU defects (in terms of genital)

> the genital decreases the urine output due to the CREA which is suppose to be excreted is reabsorb again and goes into the circulation.

Skeletal System > pain at the joint > occur only when metabolic process is affected

Integumentary System

> itching

> pallor> edema

>pruritus

> due to the CREA that is not excreted, can expel out by perspiration which is very irritating> due to urochrome retention>due to Na and water retention from reduced glomerular filtration rate> may be associated with hyperphosphatemia that results from renal failure

Cardiovascular System

> high Blood Pressure > due to Na and water retention from reduced glomerular filtration rate

Respiratory System

> pulmonary edema > results from excessive fluid in the body that reaches in the lungs

> dyspnea > that results from pulmonary edemaNervous System > decrease level of

consciousness> lethargy

> due to electrolyte imbalance

> mental and physical sluggishnessMuscular System

> muscle weakness > due to electrolyte imbalance, atrophy and collection of uremic toxins

Hematologic System

> anemia

> Uremia

> due to erythropoietin are not produce which helps bone marrow to make RBC> presence of abnormal levels of urea and other nitrogenous products in the blood due to the kidney cannot excrete it