Jointly sponsored by the Tennessee AIDS Education and Training Center, the Comprehensive Care Center, Vanderbilt School of Medicine, Vanderbilt-Meharry Center for AIDS Research and Vanderbilt Clinical Trials Center

November 2, 2007

Willis Conference Center • Nashville, Tennessee

Using New Antiretroviral Agents Wisely

10Th ANNuAl hIV SympoSIum

Explosion of Knowledge

November 2, 2007

8:00 - 8:30 am Registration and Continental Breakfast

8:30 - 8:40 am Welcome and Introduction Victoria Harris, EdD

8:40 - 8:50 am Opening Remarks and Symposium Objectives Stephen Raffanti, MD, MPH

8:50 - 9:50 am The Newest Drugs for hIV Therapy Joseph Eron, Jr., MD

9:50 - 10:05 am BREAK

10:05 - 11:05 am hIV Tropism Testing and Resistance to Co-Receptor Tropism Antagonists

Eoin Coakley, MD

11:05 am - 12:05 pm protease Inhibitors- Selection among the options Richard Haubrich, MD

12:05 - 12:15 pm Question and Answer Session

12:15 - 1:15 pm Lunch in Atrium (special breakout sessions for nurses)

1:15 - 2:15 pm NRTI Complications in a New hAART Era: Wielding the Sword Wisely Todd Hulgan, MD, MPH

2:15 - 2:30 pm BREAK

2:30 - 3:30 pm Dermatologic manifestations of hIV Disease and Its Treatment John Zic, MD

3:30 - 3:50 pm Closing Perspective Richard D’Aquila, MD

3:50 - 4:00 pm Wrap Up and Door Prize Drawing Stephen Raffanti, MD, MPH Victoria Harris, EdD

program

Course DirectorStephen p. Raffanti, mD, mphAssociate Professor of MedicineVanderbilt School of MedicineChief Medical Officer, Comprehensive Care CenterNashville, Tennessee

Course Co-DirectorVictoria l. harris, EdDDirector of EducationComprehensive Care Center Associate in MedicineVanderbilt UniversityNashville, Tennessee

FacultyBeverly R. Byram, mSN, ApNDirector of Women’s Health ServicesComprehensive Care CenterAdjunct Faculty Vanderbilt University School of NursingNashville, Tennessee

Eoin Coakley, mDSenior Medical DirectorMonogram Biosciences, Inc.South San Francisco, California

Joseph J. Eron, Jr., mDProfessor of MedicineDirector, Clinical Core, CFARUniversity of North Carolina School of MedicineChapel Hill, North Carolina

Richard haubrich, mDProfessor of MedicineDepartment of Medicine, Division of Infectious DiseasesUniversity of California, San DiegoSan Diego, California

Todd m. hulgan, mD, mphAssistant Professor of Medicine,Division of Infectious DiseasesCenter for Health Services ResearchVanderbilt School of MedicineNashville, Tennessee

John A. Zic, mDAssistant Professor of Medicine Dermatology Director, VU Cutaneous Lymphoma ClinicVanderbilt School of MedicineNashville, Tennessee

faculty

Course DescriptionIn the 26 years following the recognition of AIDS and the subsequent realization of a HIV pandemic, there have been milestones in the evolution of effective care. The introduction of the non-nucleoside reverse transcriptase inhibitors and the protease inhibitors heralded a new era, effectively treating HIV infection and preventing the development of AIDS. Data emerged showing that effective treatment of HIV positive pregnant women resulted in very low transmission of HIV infection to their children. Most recently, new antiretrovirals and new formulations of antiretrovirals have offered patients the opportunity of controlling their virus while taking only a few pills a day. Although treatment associated toxicities still prove to be a challenge for clinicians and patients alike, new strategies hold out promise. We are now at a point where another, equally significant, advance in care is about to take place. New classes of antiretrovirals and new technology will expand our ability to aggressively treat patients with even the most resistant strains of HIV. This Symposium addresses this explosion of information in a way that allows clinicians to bring useful information back to the patient. Joe Eron will address the latest data on integrase inhibitors and how they might fit into the current strategies. Eoin Coakley will discuss CCR5 tropism and the agents directed at co-receptors. Richard Haubrich will discuss some of the data on the latest protease inhibitors and Todd Hulgan will review the latest data on toxicities associated with NRTI. John Zic will round out the day with a presentation of dermatologic manifestations of HIV disease.

program objectives Upon completion of the Symposium, participants will be able to:1) discuss integrase inhibitors and state how they will use them with other antiretroviral

therapies.2) describe CCR5 tropism and the agents directed at co-receptors.3) review the latest data on treatment-related toxicities, particularly those associated

with NRTIs.4) identify and contrast the latest data on protease inhibitors.5) name three dermatological manifestations of HIV disease and how to treat them.6) examine what’s new in women’s HIV care

Target AudienceThe content of this Symposium will be invaluable for any healthcare provider seeking a comprehensive update in HIV/AIDS care. The program is designed for Physicians, Advanced Practice Nurses, Nurse Practitioners, Physician Assistants, Nurses, Oral Health Providers, Pharmacists, and other healthcare professionals interested in clinical HIV/AIDS topics.

CreditThis activity has been planned and implemented in accordance with the Essentials Areas and Policies of the Accreditation Council for CME (ACCME) through the joint sponsorship of Vanderbilt University School of Medicine, Vanderbilt Meharry Center for AIDS Research, Vanderbilt AIDS Clinical Trial Center and Vanderbilt Division of Infectious Diseases.

general information

Vanderbilt University School of Medicine is accredited by the Accreditation Council for CME to sponsor continuing medical education for physicians.

Vanderbilt School of Medicine designates this educational activity for a maximum of 6 AMA PRA Category 1 Credit(s)™. Physician should only claim credit commensurate with the extent of their participation in the activity.

This Program is pending CNE credit. Vanderbilt Medical Center Nursing Education & Development will be reviewing this Program with the Office of Lifelong Learning, Vanderbilt University School of Nursing (VUSN). VUSN is an approved provider of continuing education in nursing by the Tennessee Nurses Association (TNA). TNA is accreditated as an approver of continuing education in nursing by the American Nurses Credentialing Center’s Commission on Accreditation.

Commercial SupportThis symposium is made possible by major unrestricted educational grants from several commercial entities. Vanderbilt School of Medicine, Vanderbilt Meharry Center for AIDS Research, Vanderbilt AIDS Clinical Trial Center and Vanderbilt Division of Infectious Diseases express appreciation to the following companies for support of this educational activity by providing unrestricted educational grants.

Merck & Co., Inc.Boehringer Ingelheim Pharmaceuticals, Inc.Nashville Pharmacy Services, LLCTibotec Therapeutics Faculty DisclosuresIt is the policy of Vanderbilt School of Medicine that participants in CME activities be made aware of any affiliation or financial interest that may affect the speaker’s presentation(s). Each speaker has completed and signed a conflict of interest statement. The faculty members’ relationships will be disclosed to the audience. Registration FeesRegistration fees include access to all sessions, course materials, continental breakfast, lunch and refreshment breaks. The registration fee for this symposium is $65 for physicians and other healthcare providers. An additional fee of $20 will be charged to issue certificates for AMA PRA Category 1 Credits, nursing CNE or certificates of attendance.

Symposium ScholarshipsA limited number of course scholarships are available for qualified registrants. If you are interested in learning more about the HIV Symposium Scholarships, please contact Victoria Harris, EdD for approval. You may reach Dr. Harris at 615-321-9556 ext. 251. Approval must be obtained prior to registering for the symposium and should be noted on your registration form.

Cancellation policyIf you must cancel your registration for this course, Comprehensive Care Center will refund your registration fee, less a $25 administrative fee, provided you notify us by October 15, 2007. No refunds will be made after that date. Exceptions will be made for justifiable emergencies. In the event of cancellation or rescheduling of this CME activity due to unforeseen circumstances, Comprehensive Care Center will refund registration fees in full. Comprehensive Care Center is not responsible for non-transferable, non-refundable airline tickets or hotel accommodations purchased in connection with attendance at this CME activity.

Accommodations and TravelAll sessions of the 10th Annual HIV Symposium will be held at Willis Conference Center. Arrangements have been made for accommodations at the Embassy Suites Nashville - Airport. Room reservations should be made directly with Embassy Suites Nashville no later than October 18, 2007.

Embassy Suites Nashville - Airport10 Century BoulevardNashville, TN 37214615-871-0033Single/Double $139 plus taxTo make a reservation for your hotel room, please visit:http://embassysuites.hilton.com/en/es/groups/personalized/BNANAES-605-20071101/index.jhtml

Americans with Disabilities ActIt is the policy of Vanderbilt University School of Medicine not to discriminate against any person on the basis of disabilities. If you feel you need services or auxiliary aids mentioned in this act in order to fully participate in this continuing education activity, please call Nashville Meetings at (615) 351-7535 or attach a note to your registration form.

Further InformationFor additional information please contact:Victoria Harris, EdDComprehensive Care Center615-321-9556 x251victoria.harris@vanderbilt.eduorDiana NaisbyNashville Meetings615-351-7535

Registrant InformationName:

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Mailing Address:

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Email:

Business phone: Fax number:

Last 4 digits of Social Security #:

Profession: MD PA NP RN Other

VU Net ID (Vanderbilt employees only)

Registration FeeAll healthcare providers $65Registration received after October 15, 2007 or on-site add $25

Certificate Fee (please choose one) AMA PRA Category 1 Credit $20 Nurse CE $20 Certificate of Attendance $20Total $Registration will be confirmed only after payment is received.

Register by Fax or by mail:

• Fax registration and payment information to 615-312-1147• Mail registration and payment to: Nashville Meetings, Diana Naisby, 536 Skyview Drive,

Nashville, TN 37206. Make checks payable to: Comprehensive Care Center

You may pay by Visa, MasterCard or American Express Credit card #:

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