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FOCUS SESSION Why a Focus Session on endoscopic third ventriculostomy in infants? Wolfgang Wagner Received: 28 October 2005 / Published online: 30 August 2006 # Springer-Verlag 2006 Since its renaissancein the late 1980s, endoscopic third ventriculostomy (ETV) gained a growing acceptance and, eventually, an established place in the surgical treatment of obstructive hydrocephalus. It soon became clear, however, that a part of the patients undergoing that endoscopic procedure eventually failed and that the chance of curing the hydrocephalus by endoscopy alone (without a shunt) depended on several factors, from which patients age and etiology of hydrocephalus are the most important. Most pediatric neurosurgeons agree that ETV has a higher failure rate in infants as opposed to children, adolescents, or adults. As some of us (not all) have found very low success rates in the first months of life, the question of whether this procedure should be offered at all to our youngest patients or whether it should be reserved to infants beyond the first or second year of life was raised. Similar considerations concern the role of etiology: there is general consensus that patients with isolated aqueductal stenosis are good candidatesfor ETV, whereas newborns with hydrocephalus in the context of myelomeningocele should be treated with shunts. But what kind of treatment should be chosen in other etiologies? How should mixed forms of obstructive/absorptive hydrocephalus be dealt with? Which kind of preoperative imaging is indispens- able? Are there differences between ETV and shunts in the first year of life, with respect to complications or neurologic long-term outcome? This series of articles is intended to give an actual overview over the different important aspects of ETV in infants, particularly in the first year of life. The role of preoperative imaging, frequency and type of complications, and neurologic development after ETV vs shunt are dealt with, as well as the impact of age on success rate, indications for ETV in pathologies different from isolated aqueductal stenosis, or the relevance of a spectrum classificationof absorptive vs obstructive hydrocephalus for the choice of the appropriate treatment procedures. Of course, this Focus Session not only gives more or less established answers, but also addresses questions that still remain open. In particular, the important issue of final neurodevelopmental outcome of children treated by ETV or shunt can be dealt with only by a prospective and randomized study, following the patients over years, as is intended to be realized by the ongoing International Infant Hydrocephalus Study (IIHS). While this Focus Session reflects our present knowledge, we are optimistic that the future will clarify questions that at the moment must be left unanswered. Childs Nerv Syst (2006) 22:1527 DOI 10.1007/s00381-006-0188-2 W. Wagner Section of Paediatric Neurosurgery, Department of Neurosurgery, University Hospital Mainz, Mainz, Germany W. Wagner (*) Neurochirurgische Klinik und Poliklinik, Bereich Pädiatrische Neurochirurgie, Johannes Gutenberg-Universität, Langenbeckstrasse 1, 55131 Mainz, Germany e-mail: [email protected]

Why a Focus Session on endoscopic third ventriculostomy in infants?

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FOCUS SESSION

Why a Focus Session on endoscopic third ventriculostomyin infants?

Wolfgang Wagner

Received: 28 October 2005 / Published online: 30 August 2006# Springer-Verlag 2006

Since its “renaissance” in the late 1980s, endoscopic thirdventriculostomy (ETV) gained a growing acceptance and,eventually, an established place in the surgical treatment ofobstructive hydrocephalus. It soon became clear, however,that a part of the patients undergoing that endoscopicprocedure eventually failed and that the chance of curingthe hydrocephalus by endoscopy alone (without a shunt)depended on several factors, from which patient’s age andetiology of hydrocephalus are the most important.

Most pediatric neurosurgeons agree that ETV has ahigher failure rate in infants as opposed to children,adolescents, or adults. As some of us (not all) have foundvery low success rates in the first months of life, thequestion of whether this procedure should be offered at allto our youngest patients or whether it should be reserved toinfants beyond the first or second year of life was raised.Similar considerations concern the role of etiology: there isgeneral consensus that patients with isolated aqueductal

stenosis are “good candidates” for ETV, whereas newbornswith hydrocephalus in the context of myelomeningoceleshould be treated with shunts. But what kind of treatmentshould be chosen in other etiologies? How should mixedforms of obstructive/absorptive hydrocephalus be dealtwith? Which kind of preoperative imaging is indispens-able? Are there differences between ETV and shunts in thefirst year of life, with respect to complications or neurologiclong-term outcome?

This series of articles is intended to give an actualoverview over the different important aspects of ETV ininfants, particularly in the first year of life. The role ofpreoperative imaging, frequency and type of complications,and neurologic development after ETV vs shunt are dealtwith, as well as the impact of age on success rate,indications for ETV in pathologies different from isolatedaqueductal stenosis, or the relevance of a “spectrumclassification” of absorptive vs obstructive hydrocephalusfor the choice of the appropriate treatment procedures.

Of course, this Focus Session not only gives more or lessestablished answers, but also addresses questions that stillremain open. In particular, the important issue of finalneurodevelopmental outcome of children treated by ETVorshunt can be dealt with only by a prospective andrandomized study, following the patients over years, as isintended to be realized by the ongoing International InfantHydrocephalus Study (IIHS). While this Focus Sessionreflects our present knowledge, we are optimistic that thefuture will clarify questions that at the moment must be leftunanswered.

Childs Nerv Syst (2006) 22:1527DOI 10.1007/s00381-006-0188-2

W. WagnerSection of Paediatric Neurosurgery, Department of Neurosurgery,University Hospital Mainz,Mainz, Germany

W. Wagner (*)Neurochirurgische Klinik und Poliklinik,Bereich Pädiatrische Neurochirurgie,Johannes Gutenberg-Universität,Langenbeckstrasse 1,55131 Mainz, Germanye-mail: [email protected]