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10-min presentation on the author name problem, the ORCID initiative and two key applications of digital identity for researchers: i) attribution for data publication and ii) access control for sensitive research data
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G. A. Thorisson www.gen2phen.org
3rd Human Variome Project Meeting, Paris, 10-14 May, 2010
Who’s who on the Web?Digital identity for tracking contributions
and managing data access
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Gudmundur A. Thorisson <[email protected]>Brookes lab
Department of GeneticsUniversity of Leicester, UK
-- Outline --• The author name problem and the challenge of attribution
• Unique identifiers for authors - the ORCID initiative
• A digital identity on the Internet - IDs for researchers?
• Introduce several identity-based projects in our group
• Attribution for data publications
• Access control for sensitive data
G. A. Thorisson www.gen2phen.org
3rd Human Variome Project Meeting, Paris, 10-14 May, 2010
Non-unique names are a majorproblem in the scholarly literature
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How about these?
Are these authors all the same person?G. Thorisson, Univ. LeicesterG. A. Thorisson, Univ. LeicesterG. A. Thorisson, Cold Spring Harbor Laboratory
J. SmithJ. SmithJ. SmithJ. SmithJ. Smith [etc.]
Or these?
∼2/3 of the ∼6 million authors in MEDLINE share a last name and first initial with at least one other author, and an ambiguous name refers to ∼8 persons on average.Torvik and Smalheiser. Author name disambiguation in MEDLINE. ACM Transactions on Knowledge Discovery from Data (2009) vol. 3 (3)
G. A. Thorisson www.gen2phen.org
3rd Human Variome Project Meeting, Paris, 10-14 May, 2010
Unique identifiers for authors contributors
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Dec’09: launch of the Open Researcher Contributor Identification Initiative - ORCID
ORCID ID: B-1242-2010G. Thorisson, Univ. LeicesterG. A. Thorisson, Univ. LeicesterG. A. Thorisson, Cold Spring Harbor Lab.
automated author disambiguation+
author involvement
ORCID ID: G-1442-2009J. Smith, Univ. North Pole
ORCID ID: D-2400-2010J. Smith, Luthor Corporation
Informatics infrastructure:i) for researchers to manage profilei) interaction with other systems
G. A. Thorisson www.gen2phen.org
3rd Human Variome Project Meeting, Paris, 10-14 May, 2010
• =
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G. A. Thorisson www.gen2phen.org
3rd Human Variome Project Meeting, Paris, 10-14 May, 2010
Digital identity - an online ‘presence’
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Problem: the Web ‘me’ is fragmentedacross many identity silos
Self-asserted
Identity = The collective aspect of the set of characteristics by which a thing is definitively recognizable or known (dictionary.com)
Many usernames/passwords- password fatigue -
Asserted by others
Nature Rev Genet G. A. Thorisson <authored> Nat Biotechnol (2009) vol. 27 (11)Nature Biotech G. A. Thorisson <authored> Nat Rev Genet (2009) vol. 10 (1) [...]
Nature Rev Genet B-1242-2010 <authored> Nat Biotechnol (2009) vol. 27 (11)Nature Biotech B-1242-2010 <authored> Nat Rev Genet (2009) vol. 10 (1) [...]
G. A. Thorisson www.gen2phen.org
3rd Human Variome Project Meeting, Paris, 10-14 May, 2010
Bridging the silos - distributed identity systems
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Open, lightweight decentralised
authentication protocol
Web 2.0social networking
-Federated authentication-
Closed-world: Single sign-on (SSO) across the federation
-reuse profile information- username/pwd problem
Institution-centricidentityuser gt50 at University of Leicester
User-centric identity
Open-world: SSOacross the entire Web
G. A. Thorisson www.gen2phen.org
3rd Human Variome Project Meeting, Paris, 10-14 May, 2010 7
>50,000 websites now accepting 3rd party IDs (from www.janrain.com)
G. A. Thorisson www.gen2phen.org
3rd Human Variome Project Meeting, Paris, 10-14 May, 2010 8
ORCID ID: B-1242-2010G. Thorisson, Univ. LeicesterG. A. Thorisson, Univ. LeicesterG. A. Thorisson, Cold Spring Harbor Lab.
http://mummi.myopenid.com
A digital identity for researchers centred on
scholarly profile?
G. A. Thorisson www.gen2phen.org
3rd Human Variome Project Meeting, Paris, 10-14 May, 2010
• Identity-enabled access management– Controlling access to protected resources on the Web
• Tracking contributions– data submissions to central repositores
– data curation / micro-attribution
– crucial to bio-resource impact factor + nanopublications
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Data-related applications for digitalidentity (a.k.a ‘researcher IDs’)
G. A. Thorisson www.gen2phen.org
3rd Human Variome Project Meeting, Paris, 10-14 May, 2010
Cafe RouGE for mutation data exchange
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1. Diagnostic laboratories
2. Central mutation
depot
3. End-users (e.g. LSDB curators)
Publish data
Owen Lancaster, Session 10, Thu 10:10am
Retrieve RSS feeds
•Security•Log in via OpenID and other 3rd party identity (aka ‘outsourced’ security)•Identity-based management of access to non-open data
•Attribution•Link ORCID ID with variation data submissions => publication credit •B-1242-2010 <authored> doi:10.9354/caferouge0005 (Cafe RouGE entry 0005, 19/12/2009)
DOIs for scholarly publications vs DOIs for datasets
http://www.datacite.org
“Our long term vision is to support researchers by providing methods for them to locate, identify, and cite research datasets with confidence.”
G. A. Thorisson www.gen2phen.org
3rd Human Variome Project Meeting, Paris, 10-14 May, 2010
HGVbaseG2P - a centralgenetic association database
• Controlled access to aggregate GWAS datasets
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http://www.hgvbaseg2p.org Robert Free, Session 10, Thu 11:30am
G. A. Thorisson www.gen2phen.org
3rd Human Variome Project Meeting, Paris, 10-14 May, 2010
Molgenis-based distributedG2P data infrastructure
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• Identity-based access control + attribution
http://www.molgenis.org Morris Swertz, Session 10, Thu 9:40am
G. A. Thorisson www.gen2phen.org
3rd Human Variome Project Meeting, Paris, 10-14 May, 2010 13
The GEN2PHEN Strategy
A federated network of databases, not a central database
Data import systems
Data standards
Database solutions
Locus-specific databases
‘Genomics’ G2P databases
Data exchange mechanisms
The GEN2PHEN Knowledge Centre will fully leverage this network
GEN2PHENKnowledge
Centre
http://www.gen2phen.org Adam Webb, Session 10, Thu 9:40am
G. A. Thorisson www.gen2phen.org
3rd Human Variome Project Meeting, Paris, 10-14 May, 2010 14
GEN2PHEN Consortiumhttp://www.gen2phen.org/about-gen2phen/partners
University of Leicester
-Anthony J. Brookes Bioinformatics Group
Tim Beck
Rob Free
Sirisha Gollapudi
Rob Hastings
Owen Lancaster
Adam Webb
-Raymond Dalgleish
This work has received funding from the European Community's Seventh Framework Programme (FP7/2007-2013)under grant agreement number 200754 - the GEN2PHEN project.
Acknowledgements
Contact me! Gudmundur A. Thorisson <[email protected]>
