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WHO Lyon OfficeDr. Brad Kay March 2002
WHO Lyon OfficeDr. Brad Kay March 2002
Globalization Globalization and poverty: Fertile ground for and poverty: Fertile ground for infectious diseasesinfectious diseases
WHO Lyon OfficeDr. Brad Kay March 2002
NIPAHLASSAFEVER
EBOLA
CJDHEPATITIS C
DRUG RESIST
INF.
MONKEYPOX
DENGUE
WEST NILEFEVER
CHOLERA
PLAGUE MENINGITIS
YELLOWFEVER
PNEUMONIA
DIARRHOEALDISEASESMALARIA
AIDS
TUBERCULOSIS(TB) MEASLES
SCHISTO
GUINEAWORM
FILARIASIS
CHAGAS
LEPROSY
POLIO
INTESTINALPARASITES
ONCHO
Infectious Diseases: Obstacles to Social and Economic DevelopmentInfectious Diseases: Obstacles to Social and Economic Development
Diseasesof
Poverty
WHO Lyon OfficeDr. Brad Kay March 2002
Emerging / Re-emerging infectious diseases, 1996 to 2001
Cryptosporidiosis
Lyme Borreliosis
Reston virus
VenezuelanEquine Encephalitis
Dengue haemhorrhagic fever
Cholera
E.coli O157
West Nile Fever
Typhoid
Diphtheria
E.coli O157
EchinococcosisLassa feverYellow fever
Ebola haemorrhagicfever
O’nyong-nyong feverHuman Monkeypox
Cholera 0139
Dengue haemhorrhagicfever
Influenza A(H5N1)
Cholera
RVF/VHF
nvCJD
Ross River virus
Equine morbillivirus
Hendra virus
BSE
Multidrug-resistant Salmonella
E.coli non-O157
West Nile VirusMalaria
Nipah Virus
Reston Virus
Legionnaire’s Disease
Buruli ulcer
WHO Lyon OfficeDr. Brad Kay March 2002
Impact of Infectious Disease Outbreaks,
1990–2000
UKBSE
US$ 39 billion1990-1998
TanzaniaCholera
US$ 36 million1998
IndiaPlague
US$ 1.7 billion1995
PeruCholera
US$ 770million1991
MalaysiaNipah
Pig destruction1999
Hong Kong,ChinaInfluenza A(H5N1) Poultry destruction
1997
USA E. coli / 0157
Food recall/destructionPeriodically
WHO Lyon OfficeDr. Brad Kay March 2002
Contain known risks
Contain known risks
Improve preparedness
Improve preparedness
Respond to the unexpected
Respond to the unexpected
G L O B A L P A R T N E R S H I P
E P I D E M I C A L E R T & R E S P O N S E
I N T E R N A T I O N A L H E A L T H R E G U L A T I O N S
WHO Lyon OfficeDr. Brad Kay March 2002
Toward Global Health Security: Epidemic Alert and Response
� Specific interventions for major epidemic-prone diseases (cholera, yellow fever…)
� WHO Global Epidemic Alert & Response Network (WHO global epidemic intelligence and international response)
� National capacity strengthening (epidemiology and laboratory strengthening)
WHO Lyon OfficeDr. Brad Kay March 2002
WHO CSR Lyon Officestrengthening national diagnostic
capacities
� Fills neglected and under-funded areas by:● Strengthening national public health laboratories ● Supporting field epidemiology training programmes● Strengthening laboratory linkages to outbreak detection
& response activities
� Provides a focus for global partnerships in strengthening laboratories for disease surveillance
WHO Lyon OfficeDr. Brad Kay March 2002
WHO CSR Office in Lyon
WHO Lyon OfficeDr. Brad Kay March 2002
Strengthening National Laboratory Capacities
� core diagnostic expertise� availability of essential reagents� good management practices� integration with surveillance activities� quality control practices
WHO Lyon OfficeDr. Brad Kay March 2002
Establishing laboratory support for common public health diseases
WHO Lyon OfficeDr. Brad Kay March 2002
Providing laboratory support for catastrophic public health events
WHO Lyon OfficeDr. Brad Kay March 2002
A two-year programme
� One 8-week introductory module in Lyon� Two 3-week follow-up modules in Lyon� 2 in-country periods
2 months 4-6 months 3 weeks 16-18 months 3 weeksLyonLyon Lyon
WHO Lyon OfficeDr. Brad Kay March 2002
Profile of the trainees
� Experienced microbiologists/lab specialists
� Wording in the national reference laboratory
� Involved with detection of epidemic-prone diseases
� Responsible for the quality control programme
WHO Lyon OfficeDr. Brad Kay March 2002
Initial Lyon Module(8 weeks)
� Module one 1- Review of core laboratory procedues, elements of
surveillance, use of information technology2- Establishing laboratory-based surveillance activities3- Administrative issues: laboratory management, quality
control, data and communications, public relations Methods� Case studies� Computer lab� Lectures/presentations� Group discussions, role play
WHO Lyon OfficeDr. Brad Kay March 2002
Laboratory training at the Institute of Pharmaceutical and
Biological Sciences
WHO Lyon OfficeDr. Brad Kay March 2002
Computer lab
WHO Lyon OfficeDr. Brad Kay March 2002
- Integrated case-studies using:- Microbiology- Epidemiology- Laboratory management
WHO Lyon OfficeDr. Brad Kay March 2002
Participants produce a three-part plan of action
� Laboratory operations� Surveillance activities� Communications linkages
WHO Lyon OfficeDr. Brad Kay March 2002
The Goal:To strengthen public health
laboratory practice in disease surveillance and control programs
WHO Lyon OfficeDr. Brad Kay March 2002
Thank you
