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What is a Systematic review?
Systematic reviewCombination of the best research projects in a
specific area• Selecting• Identifying• Synthesizing
Health care sciences:
Clinical tests Social interventions Medicine and
healthcareEconomic evaluations
Public and health interventions
Traditional review Systematic review
They are not led by peer-reviewed protocol and it is no possible to replicate
the findings
They are led by peer-reviewed protocol and it is possible to replicate the findings
They are not explicit about how studies are selected, assessed and integrated
They are explicit about how studies are selected, assessed and integrated
Lack of rigor High quality of rigor
Different conclusions Common conclusion between reviewers
Defining questions
Searching literature
Assessing studies
Combining results
Discuss results
Meta- analysisStatistical research technique
Combination of:o Quantitativeo Qualitative
Statistical difference between 2 treatments
Advantages
1. Overcoming bias. Narrative reviews could introduce bias. A meta-analysis can overcome these dangers.
2. Precision. These researches detect clinical significant effects.
3. Transparency. Allow readers to determine the reasonableness of the decisions taken.
Location of studies
Quality assessmen
t
Effect sizeAvoid
publication bias
Sensitivity analysis