Welcome to BIOL 252Anatomy and Physiology

http://www.youtube.com/watch?v=ZRoSy1Hwouo

Welcome to BIOL 252Anatomy and Physiology

Dr. Gidi Shemerbishemer@email.unc.edu

Office: Wilson G41Office hours: Tue and Thur 02:00-04:00

http://www.bio.unc.edu/courses/2009Fall/Biol252Sections456/

LabsWilson 111, 212

My officeWilson G41

Departmental Advising

For example: tutoring (every TW 6-9, or by appointment) including BIOL252

http://learningcenter.unc.edu//

http://www.bio.unc.edu/Faculty/Shemer/

Available coursesChoosing the right courseCareer decisions

Research opportunities Graduate school in BiologyResources at UNC

Departmental Advising

“Smart students take advantage of resources.Successful students seek help”

Anatomy : the study of structure

Physiology : the study of function

The lab will mainly deal with AnatomyCoordinated by Dr. Corey JohnsonSelf-work with 3D models

Quizzes on blackboard BEFORE the lab

Marieb and Hoehn, third edition

Lectures are important

Grading 25% x 3 exams = 75% lab exercises = 25%

(respect your peers)No notes providedUse the ppt handouts

Answer open questions

THINK!!! Spoonfeeding- not on my watch

Blackboard

• Announcements• Syllabus, schedule• Powerpoints• Assigned readings• Links• Grades

Bookstore only (arriving Friday)

Optional Lab Manual:

Bookstore only

Recommended for those who know themselves to be kinesthetic learners. If coloring between the lines is useful to you and helps you remember lots of information, this manual is recommended. The author feels the manual is overpriced, so you will be able to “get by” without it. A more bare-bones version will be made available through blackboard at no cost.

Lab Info:• Lab is a co-requisite. Students not enrolled for a

lab will be dropped from lecture enrollment.• Labs begin Monday, August 31• A syllabus will appear on your lab blackboard site

in the next week• You will likely have an assignment due on your

first day of lab. Pay attention to the “announcements” section of you lab blackboard site.

Registration

Sign-up sheet available up front

Those with relevant needs have prioritymajor requirement – nursing, pharmacy, etc.Otherwise: Seniors > Juniors > Sophomores

Being pre- (med, dental, vet, ophthalmology, etc.) does not constitute a priority

HomeostasisPhysiology

how the varied components of living things adjust to maintain a constant

internal environment that makes possible optimal functioningWB Cannon

Homeostasis

So we have a balanced state, but it is NOT static!!

Homeostatic Imbalance = Diseases (e.g. diabetes)

Anatomy

Gross Anatomy- study of structures visible to the naked eye

Microscopic Anatomy- study of structures visible ONLY with a microscope

Chemical

Cellular

Tissue

OrganOrgan system

Organismal

Levels of organization

Planes of the Body

Frontal plane

Sagittal planemid/ para

Transverse plane

Body Cavities

Covering and Lining Membranes

Cutaneous Membrane(covering the surface)

Mucous Membranes(open to the exterior)

Serous Membranes(moist)

Covering and Lining Membranes of the Ventral Body Cavity

Covering and Lining Membranes of the Ventral Body Cavity

Chemical

Cellular

Tissue

OrganOrgan system

Organismal

Levels of organization

Support Protect

Movement Control

Different Tissues can be Found in One Organ

Epithelial Tissue

1) Covering and lining epithelium

2) Glandular epithelium

Functions1) Protection (e.g. skin)2) Sensory Reception (e.g. skin)3) Absorption (e.g. intestine)4) Secretion and Filtration (e.g. kidney)

e.g. = exempli gratia, "for the sake of an example"

Epithelial Cells are Closely Bound Together

Epithelial Cells are Closely Bound Together

Epithelial Cells are Polarized

Apical- towards the lumen/surfaceBasal- towards underlying cells

Lateral- contacting other epithelial cells

Apical

Basal

Polarized

Closely Bound Together

Avascular but Innervated

High Regenerative Capacity

Characteristics of Epithelial Cells

Classification of Epithelia

squamous cuboidal columnar

simple

stratified

Epithelial Tissue

1) Covering and lining epithelium

2) Glandular epithelium

Glandular Epithelia

Endocrine Glands: secreting internally, to the extracellular space

Exocrine Glands: secreting externally, to the body surface or body cavities

A Gland: cell/s that make and secrete products.

Endocrine Glands: secreting internally, to the extracellular space (hormones)

Exocrine Glands: secreting externally, to the body surface or body cavities

A goblet cell, secreting mucin

Modes of Secretion

Merocrine Holocrine

The connective Tissue

Connective Tissue

FunctionsSupport

ProtectionInsulationTransport

Connective TissueCells

+ Extracellular Matrix (ECM)

http://fulton.edzone.net/

Extracellular Matrix (ECM)

Ground Substance+

Fibers

Proteoglycans (GAGs + a core proteins)

Tissue fluid

Adhesion proteins

Ground Substance

Extracellular Matrix (ECM)

Ground Substance+

Fibers

BoneTendo

n

Fibers of connective tissues

Collagen fibers Reticular fibers Elastic fibers

Defect in collagen assembly

Connective TissueCells

+ECM = ground substance+ fibers

http://fulton.edzone.net/

Connective Tissues

Connective tissue proper

Fibroblasts Osteoblasts Chondroblasts Blood cells

Bone Cartilage Blood

Loose Areolar Adipose

Dense regular Dense irregular

Loose Connective Tissue

Dense Connective Tissue

Connective tissue proper

Loose connective tissue: AreolarConnective tissue proper

supports and binds tissues

a reservoir of water and nutrients

defense (macrophages)

Homeostatic Imbalance

Edema

Please read and understand Fig. 4.9 (a-e) in your textbook

Loose Areolar Adipose

Dense regular Dense irregular

Connective tissue proper

Loose Areolar Adipose

Dense regular Dense irregular

Loose Connective Tissue

Dense Connective Tissue

Connective tissue proper

Connective Tissues

Connective tissue proper

Fibroblasts Osteoblasts Chondroblasts Blood cells

Bone Cartilage Blood

Next: the body’s organ systems The Integumentary System

http://www.mvla.net/