B

0

1

2

3

4

5

6

7

TG2

gene

ex

pres

sion

(fol

d)

Warfarin: - + + Quercetin: - - +

**

0

40

80

120

160

TG2

activ

ity

(mU

/mg

prot

ein)

Warfarin: - + + Quercetin: - - +

**A *

Supplemental Figure 3

axin2 cycD1 Tcf4

0

1

2

3

4

5

b-ca

tenin

depend

ent

gene exp

ression (fol

d)

Warfarin: - + + - + + - + + Quercetin: - - + - - + - - +

* ** *

**** **

C