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Véronique ÉPARVIER Research Engineer 1st class CNRS
Personnal information Professional contact
Date of Birth May-13 1976 Institut de Chimie des Substances Naturelles
Married, 2 children CNRS - UPR2301, Bâtiment 23B
E-mail: [email protected] 1 avenue de la terrasse
Web site: http://www.icsn.cnrs-gif.fr 91198 Gif-sur-Yvette
Tel: +33 (0)1 69 82 36 79
Professionnel career 2010- Research engineer CNRS in chemical analysis, ICSN.
2008-2010 Research engineer in chemical analysis, CNRS Guyane
2006-2008 Research engineer CNRS at IRD, Cayenne, French Giuana.
Research Theme Chemistry of Natural Substances, symbiotic microorganisms, bio-inspiration,
metabolomics
Publications 44 publications, 3 patents, 20 conference articles, 4 guest lectures, 10 oral conferences.
Supervision 4 theses supported, 3 theses in progress, 14 Master2 Research
Committees 1 Thesis jury, 10 middle-doctorate juries
Distinction Laureate of the Air Liquide Trophy for scientific research in the field of the environment,
obtained for the FEDER Insecticide project.
Notable responsibilities Responsible for the library of strains of symbiotic microorganisms (souchothèque) of the ICSN (2010-)
Head of the team "Chemical ecology and microbial secondary metabolites", CNRS-ICSN (2015-2017)
Member of the Scientific Council of Labex CEBA (Center for the Study of Biodiversity Amazonian, 2012-)
Elected member of the laboratory council of the Institute of Chemistry of Natural Substances (2015-)
Education 2013 Habilitation to conduct researches Université Paris Sud 11, Paris-Saclay.
Speciality: Pharmaceutical Sciences
Title: Bioactive secondary metabolites from plants and symbiont microorganisms. Chemical,
biological, metabolomic and ecological studies. October-10 2013.
2005 PhD Thesis of the National Museum of Natural History
Sustained November-25 2005
Doctoral School: Sciences of Nature and Human
Specialty: Natural Substances Chemistry
Mention: very honourable with jury congratulations
Title: Chemical and biological studies of tropical plants: Disepalum plagioneurum and Richella
obtusata (Annonaceae), Argophyllum nitidum (Escalloniaceae) and Pittosporum pancheri
(Pittosporaceae). Isolation, analysis and biological tests. Dir: Dr. Françoise Guéritte November-
14 2005.
2002 Master2 Sciences of Agro-resources
INPT (National Polytechnic Institute of Toulouse), ENSAT-ENSACIET, Toulouse.
2001 Master2 Bio-cultural Anthropology
LEHA (Laboratory of Human Ecology and Anthropology) Aix-Marseille III University.
Research activity My area of research activity falls within the broad field of natural substances chemistry. In this context I
am interested in the study of interactions between micro-organisms and plants and micro-organisms and insects, in
order to discover secondary metabolites having a pharmacological and agrochemical interest but also to understand
the ecological role of them. For this purpose, different methodological tools such as chemical ecology,
metabolomics and functional chemodiversity are used and developed. The goal of this research is to carry out
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integrated approaches for the study and valorization of secondary metabolites from an original resource of natural
substance: symbiotic microorganisms.
Expertise Evaluation of the annual research projects of the Labex CEBA.
Jury President for the Young Researcher Presentation Awards, Actinomycete Congress (2017)
Expertise mission for the IRD, AAP AIRD "Renovated partnership for research for development
of Côte d'Ivoire" (2017)
Workshop animation: Knowlegde and valorization of forest resources, international congress
Knowledge-based management of tropical rainforests, November 2009, Cayenne, GIP ECOFOR
(Forest Ecosystems).
Prize 2016 Laureate of the Air Liquide Trophy for scientific research in the field of the environment,
obtained for the FEDER INSECTICIDE project
2005 1st price presentation of the Young Scientist Competition
11th
NAPRECA International Congress, August 9-12, www.napreca.net/
Significant publications Sorres J., Nirma C., Eparvier V.*, Stien D.* Pseudallicins A-D, four complex Ovalicin derivatives from
Pseudallescheria boydii SNB-CN85. Organic Letters, 2017, 9, 3978–3981. Impact factor 6.579.
Sorres J., Nirma C., Barthélemy M. Eparvier V.*, Stien D. Tyroscherin and tyroscherin analogs from
Pseudallescheria boydii SNB-CN85 isolated from termite Termes cf. hispaniolae. Phytochemistry Letters 2017,
22, 142-144. Impact factor 1.418.
Touré S., Dusfour I., Stien D., Eparvier V.* Two new tetrahydrofuran derivatives from the fungus Mucor spp. SNB-
VECD11D isolated from the Chrysomelidae Acalymma bivittula. Tetrahedron Letters 2017,
https://doi.org/10.1016/j.tetlet.2017.08.031. Impact factor 2.193.
Hadj Rabia-Boukhalfa Y., Eveno Y., Karama S., Selama O., Lauga B., Duran R., Eparvier V. Isolation, purification
and chemical characterization of a new angucyclinone compound produced by a new halotolerant Nocardiopsis
sp. HR-4 strain. World Journal of Microbiology and Biotechnologie 2017, 33, 126. Impact factor 1.658.
André A., Wojtowicz N., Touré K., Stien D., Eparvier V.* New acorane sesquiterpenes isolated from the
endophytic fungus Colletotrichum gloeosporioides SNB-GSS07. Tetrahedron Letters 2017, 58, 1269-1272.
Impact factor 2.193.
Touré S., Nirma C., Falkowski M.,
Dusfour I., Boulogne I., Jahn-Oyac A., Coke M., Azam D., Girod R., Moriou C.,
Odonne G., Stien D., Houël E., Eparvier V.* Aedes aegypti larvicidal sesquiterpene alkaloids from Maytenus
oblongata Reissek (Celastraceae). Journal of Natural Products 2017, 80, 384-390. DOI
10.1021/acs.jnatprod.6b00850. Impact factor 3.281.
Peyrat L-A., Eparvier V., Eydoux V., Guillemot J-C., Litaudon M., Stien D. Betulinic acid, the first lupane-type
triterpenoid isolated from both a Phomopsis sp. and its host plant Diospyros carbonaria. Chemistry &
Biodiversity 2017, 14, e1600171. DOI: 10.1002/cbdv.201600171 Impact factor 1.440.
Peyrat L-A., Eparvier V., Eydoux C., Guillemot J-C. Stien D, Litaudon M. Chemical diversity and antiviral potential
in the pantropical Diospyros genus. Fitoterapia 2016,112, 9-15. Impact factor 2.698.
Basset C., Eparvier V., Espindola L.S. The search for antifungals from Amazonian trees : a bio-inspired screening,
Natural Product Communication, 2015, 10, 605-608. Impact factor 0.773.
Sorres J., Nirma C., Touré S., Eparvier V., Stien D. Two new pimarane diterpenoids from the endophytic fungus
Xylaria sp. Tetrahedron Letters 2015, 56, 4596-4598. Impact factor 2.193.
Mandavid H., Rodrigues A.M.S., Espindola L.S., Eparvier V.*, Stien D. Cytotoxic secondary metabolites isolated
from the Amazonian endophytic fungus Diaporthe sp. SNB-GSS10. Journal of Natural Products 2015, 4, 1735-
1739. Impact factor 3.285. Nirma C., Eparvier V.*, Stien D. Reactivation of antibiosis fungus Chrysoporthe sp. SNB-74. Journal of Antibiotics
2015, 68, 586-590. Impact factor 2.237.
Nirma C., Eparvier V.*, Stien D. Antibacterial ilicicolinic acids C and D, and ilicicolinal from Neonectria
discophora SNB-CN63 isolated from a termite nest Journal of Natural Products 2015, 78, 159-162. Impact
factor 3.285.
Casella T.M., Eparvier V., Mandavid H., Bendelac A., Odonne G., Dayan L., Duplais C., Espindola L.S., Stien
Nirma C., Eparvier V.*, Stien D. Antifungal agents from Pseudallescheria boydii isolated from termite
Nasutitermes sp. Journal of Natural Products 2013, 76, 988–991. Impact factor 3.281.
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Patents André A., Touré K., Stien D., Eparvier V. Utilisation de 2,5-dicétopiperazines en tant qu’agents cosmétique,
Demande de Brevet Français N°FR 17/51203 du 17/02/2017.
Falkowski M., Rodriguez A., Eparvier V., Dusfour I., Houël E., Stien D. Propriétés insecticides de bois de
Sextonia rubra (Mez) van der Werff (Lauraceae) et de ses constituants (rubrénolides et rubrynolide)
particulièrement contre les larves du moustique Aedes aegypti. Demande de Brevet Français
PCT/FR2015/052537 du 01/02/2015
Houël E., Rodrigues A., Raguin L., Eparvier V., Stien D. Composition antifongique comprenant une huile
essentielle d’Otacanthus azureus (Linden) Ronseʺ; Demande de Brevet Français n° FR11/55920 du 30/06/2011.
