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Vol. 268, No. 15 The Journal of May 25,1993
Biological Chemistry Copyright 0 1993 by the American Society for Biochemistry and Molecular Biology, Inc.
428 East Preston St., Baltimore, MD 21202 U.S.A.
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CONTENTS*
MINIREVIEW 10796 Cloning and characterization of complementary DNA encoding the eukaryotic initiation factor 2-associated 67-kDa protein ( ~ 6 7 ) . Shiyong Wu, Swati Gupta, Nabendu Chatterjee, Ronald E. Hileman, Terry G. Kinzy, Nancy D. Denslow, William C. Merrick, Debopam Chakrabarti, John C. Osterman. and Naba K. Gupta
Oligonucleotide x-ray structures in the study of confor- mation and interactions of nucleic acids. Olga Kennard and Stephen A. Salisbury
COMMUNICATIONS
ture of an antibody-protein antigen complex. Lata Pra- Evaluation of mutagenesis for epitope mapping. Struc-
sad, Sadhann Sharma, Margaret Vandonselaor, J . Wilson Quail, Jeremy S. Lee, E. .Bruce Waygood, Keith S. Wilson, Zbigniew Dauter, and Louls T. J . Delbaere
A novel functional target for tumor-promoting phorbol esters and lysophosphatidic acid. The p2lrac-GTPase activating protein n-chimaerin. Sohail Ahmed, Joel +e, Robert Kozma, Anthony Best, Clcnton Monfries, and Louis Lcm
The active site substrate specificity of the CAMP-
Mendelow, Jaya Srinivasan, Tae Ryong Lee, Scott Pluskey, dependent protein kinase. Young-Guen Kwon, Marianne
Allen Salerno, and David S. Lawrence
A new isoform of 11b-hydroxysteroid dehydrogenase
Naray-Fejes-Toth in aldosterone target cells. Erzsebet Rusvai and Aniko
ARTICLES GimS and G , selectively associate with the cloned so- matostatin receptor subtype SSTR2. S F a n F. Law, Ka- zuki Yasuda, Graeme I. Bell, and Terry Relscne
bovine plasma retinol-binding protein. Giuseppe Zanotti, Crystal structure of liganded and unliganded forms of
Rodolfo Berni, and Hugo L. Monaco
The two allele sequences of a common polymorphism in the promoter of the plasminogen activator inhibitor-1 (PAL-1) gene respond differently to interleukin-1 in
sten, Fiona Green, Steve Humphries, and Adriano M. Henney HepG2 cells. Sally J . Dawson, Bjorn Wiman, Anders Ham-
Alanine dehydrogenase from soybean nodule bacter- oids. Kinetic mechanism and pH studies. Mark T. Smith and David W. Emerich
Phospholipase C-y, associates with viral and cellular src kinases. Osamu Nakanishi, Futoshi Shibasaki, Michihiro Hidaka, Yoshimi Homma, and Tadaomi Takennwa
bly of the active heterodimer. Evidence for folding Refolding of luciferase subunits from urea and assem-
intermediates that precede and follow the dimerization step on the pathway to the active form of the enzyme. Miriam M. Ziegler, Michel E. Goldberg, A k i n F. Chaffotte, and Thomas 0. Baldwin
Contribution of folding steps involving the individual subunits of bacterial luciferase to the assembly of the active heterodimeric enzyme. Thomas 0. Baldwin, Miriam M. Ziegler, Alain F. Chaffotte, and Michel E. Goldberg
heterodimeric intermediate in equilibrium with the na- Folding of bacterial luciferase involves a non-native
tive enzyme and the unfolded subunits. A . Clay Clark, James F. Sinclair, and Thomas 0. Baldwin
Divergent regulation of phosphatidylinositol 3-kinase PS5a and PS5B isoforms upon T cell activation. Karin Recf, Ivan Gout, Michuel D. Waterfield, and Doreen A. Cantrell
Stimulation of aged human lung fibroblasts by extra- cellular ATP via suppression of arachidonate metabo- lism. Ning-nu Hung , Ding-ji Wang, and Leon A. Heppel
10802 Functional size analysis of F-ATPase from Escherichia coli by radiation inactivation. Jing Tyan Ma, JIU Jiu Wu, Chi Meng Tzeng, and Rong Long Pan
10808 Cyclic GMP modulates depletion-activated Ca2+ entry in pancreatic acinar cells. Trrstram 0. Bahnson, Stephen J . Pandol, and Vincent E. Dionne
10813
10820
10826
10836
10842
10851
10863
10870
10876
10881
10888
10895
10900
10906
homologue to Escherichia coli ribosomal protein 512. A novel cloning strategy reveals the gene for the yeast
Lefa E. Alksne and Jonathan R. Warner
Effects of brefeldin A and accessory proteins on am- ciation of ADP-ribosylation factors 1, 3, and 5 with
Moss, and Martha Vaughan Golgi. Su-Chen Tsai, Ronald Adamik, Randy S. Haun, Joel
Differential usage of the carboxyl-terminal region among aldolase isozymes. Luc Berthiaume, Dean R . Tolan, and Jurgen Sygusch
Selective induction by phenobarbital of the electrogenic transport of glutathione and organic anions in rat liver canalicular membrane vesicles. Jose Carlos Fern&- dez-Checa, Murad Ookhtens, and Neil Kaplowitz
Kinetic studies on benzyl alcohol dehydrogenase en-
containing long chain alcohol dehydrogenase family. coded by TOL plasmid pWW0. A member of the zinc-
Jeffrey P. Shaw, Monique Rekik, Frawoise Schwager, and Shigeaki Harayama
Characterization of RNA and DNA synthesis in Esch- erichia coli strains devoid of ppGpp. V. James Hernandez and Hans Bremer
Purification of an autocrine growth factor homologous with mouse epithelin precursor from a highly tumori- genic cell line. Jian Zhou, Guang Gao, John W. Crabb, and Ginette Serrero
Rat liver imidase. Yuh-Shyong Yang, Sengoda Ramaswamy, and William B. Jakoby
Calcium ionophore-induced transient down-regulation of c-myb mRNA levels in Friend erythroleukemia cells. Andrcis Schaefer, Ulrcch Stocker, and Hans Marquardt
heparan sulfate proteoglycan, and zinc. Dieter Reinhardt, Mapping of nidogen binding sites for collagen type IV,
Karlheinz Mann, Roswitha Nischt, Jay W . Fox, Mon-Li Chu, Thomas Krieg, and Rupert Timpl
Interaction of phosphofructokinase with tubulin and microtubules. Quantitative evaluation of the mutual
Judit Ouadi effects. Attila Lehotzky, Marianna Telegdi, Karoly Liliom, and
Identification of a novel subunit of the Type I inter- feron receptor localized to human chromosome 21. Oscar R. Colamonici and Paul Domanski
Structure-function studies of the human thyrotropin receptor. Inhibition of binding of labeled thyrotropin (TSH) by synthetic human TSH receptor peptides. John C. Morris, Elizabeth R. Bergert, and Daniel J . McCormick
Vitamin E recycling in human erythrocyte membranes. Anastasia Constantinescu, Derick Hun, and Lester Packer
* The CONTENTS arranged by Subject Categories will be found immediately following these CONTENTS. Full Instructions to Authors will be found in (1992) J. Bwl. Chern. 268, 745-753, and reprints may be obtained from the editorial office.
11
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1
1:
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1002
1008
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1028
1041
Interaction of GTPase activating proteins (GAPS) with p21- measured by a novel fluorescence anisotropy method. Essential role of Arg-903 of GAP in activation of GTP hydrolysis on ~ 2 1 ~ " . Geoffrey G. Brownbridge, Peter N. Lowe, Keith J. M. Moore, Richard H. Skinner, and Martin R. Webb
Addition of a heterologous transmembrane domain to Structure-function analysis of the Bcl-2 oncoprotein.
portions of the Bcl-28 protein restores function as a regulator of cell survival. Shigeki Tanakn, Koichi Saito, and John C. Reed
protein kinase inhibitor of CAMP-dependent protein Evidence for two additional isoforms of the endogenous
kinase in mouse. Marc0 A. Scarpetta and Michael D. Uhler
A novel protein domain required for apoptosis. Muta- tional analysis of human Fas antigen. Naoto Itoh and Shigekazu Nagata
Mannosamine inhibits the synthesis of putative glyco- inositol phospholipid anchor precursors in mammalian cells without incorporating into an accumulated inter- mediate. Daniel Sevlever and Terrone L. Rosenberry
Acetyl-coA carboxylase from yeast is an essential en- zyme and is regulated by factors that control phospho- lipid metabolism. Meinhard Hafilacher, Andreas S. Iuessa, Fritz Paltauf, and Sepp D. Kohlwein
Cal+ binding to sarcoplasmic reticulum ATPase revis- ited. I. Mechanism of affinity and cooperativity modu- lation by H+ and M8+. Vincent Forge, Elisabeth Mintz, and Florent Guilluin
Cap+ binding to sarcoplasmic reticulum ATPase revis- ited. 11. Equilibrium and kinetic evidence for a two- route mechanism. Vincent Forge, Elisabeth Mintz, and Flo- rent Guilluin
Binding and regulatory properties of expressed func- tional domains of chicken gizzard smooth muscle cal- desmon. Charles S. Redwood and Steuen B. Marston
Isolation and characterization of the human sprl gene and its regulation of expression by phorbol ester and cyclic AMP. Gang An, Johannes Tesfaigzi, Yue-Jen Chuu, and Reen W u
Transient transfection studies of secretion in bovine chromaffin cells and PC12 cells. Generation of kainate- sensitive chromaffin cells. Peter F. Wick, Ruth A. Senter, Leslie A. Parsels, Michael D. Uhler, and Ronald W. Holz
Regulation of linkages between the erythrocyte mem- brane and its skeleton by 2,3-diphosphoglycerate. Ryu- ichi Moriyama, Christian R. Lombardo, Ryan F. Workman, and Philip S. Low
Ca'+-dependent kinase and phosphatase control inositol
tion by agonist stimulation. Bin-Xian Zhang, Hong Z h , 1,4,5-trisphosphate-mediated Cap+ release. Modifica-
and Shmuel Muallem
Purification and characterization of farnesyl diphos- phate/geranylgeranyl diphosphate synthase. A ther- mostable bifunctional enzyme from Methanobacterium thermoautotrophicum. Anjun Chen and C. Dale Poulter
Functional interactions between SV40 T antigen and other replication proteins at the replication fork. Yota Muraknmi and Jerard Hurwitz
DNA polymerase a stimulates the ATP-dependent bind- ing of simian virus tumor T antigen to the SV40 origin of replication. Yota Murakami and Jerard Hurwitz
Mutational analysis of the human DNA polymerase a. The most conserved region in a-like DNA polymerases is involved in metal-specific catalysis. William C. C o p - Land and Teresa S.-F. Wang
Fidelity studies of the human DNA polymerase a. The most conserved region among a-like DNA polymerases is responsible for metal-induced infidelity in DNA syn- thesis. William C. Copeland, Naomi K. Lam, and Teresa S.-F. wang
11050 A human cDNA corresponding to a gene overexpressed during cell proliferation encodes a product sharing ho-
Marie-Th2rese Prosperi, Didier Ferbus, Isabelle Karczinski, mology with amoebic and bacterial proteins.
and Gerard Goubin
11057 Botulinum toxin inhibits arachidonic acid release as- sociated with acetylcholine release from PC12 cells. Prabhnti Ray, Jonathan D. Berman, Wilbert Middleton, and James Brendle
11065 Regulation by membrane potential of phosphatidyl-
Aidan G. M. Dauison, and Monica L. Prugue inositol hydrolysis in pancreatic islets. Trevor J . Biden,
11073 Characterization of glycoprotein I1 from bovine adre- nal medullary chromaffin granules. Identification of
parts of the lysosomal-associated membrane glycopro- components representing the secretory vesicle counter-
teins (lamp-1 and lamp-2). A. David Hieber and Dauid L. Christie
11079 Sterol 27-hydroxylase in bile acid biosynthesis. Mech- anism of oxidation of 5&cholestane-3a,7a,l2a,27-te- trol into 3a,7a,l2a-trihydroxy-5~-cholestanoic acid. Ingrid Holmberg-Betsholtz, Erik Lund, Ingemar Bjorkhem, and Kjell Wikvall
11086
11090
11097
11105
11113
11119
11125
11134
Mutants of the Bacillus subtilis multidrug transporter Bmr with altered sensitivity to the antihypertensive
Alexander A. Neyfakh, and Shimon Schuldiner alkaloid reserpine. Maqbool Ahmed, Carina M. Borsch,
Circular dichroism studies of diethyl pyrocarbonate-
Li, Dexter S. Moore, and Robert C. Rosenberg modified histidine in hen egg white lysozyme. Chingwen
Topography of glycosylation and UDP-xylose produc- tion. Ann E. Kearns, Barbara M. Vertel, and Nancy B. Schwartz
Xylosylation is an endoplasmic reticulum to Golgi
E. Kearns, and Nancy B. Schwartz event. Barbara M. Vertel, Linda M. Walters, Nina Flay, Ann
Saccharomyces cerevisiae CDC25(1028-1589) is a guanine nucleotide releasing factor for mammalian Ras
Marie-Christine Chevallier-Multon, Fabien Schweighoffer, proteins and is oncogenic in NIH3T3 cells.
Isabelle Barlut, Nicole Baudouy, Isabelle Fath, Marc Duchesne, and Bruno Tocqui
phosphorylation in regulated secretion by the pan- A role for cholecystokinin-stimulated protein tyrosine
creatic acinar cell. Manfred P. Lutz, Shari L. Sutor, Robert T. Abraham, and Luurence J. Miller
Chicken ovalbumin upstream promoter-transcription factor (COUP-TF) represses transcription from the promoter of the gene for ornithine transcarbamylase in a manner antagonistic to hepatocyte nuclear factor-4 (HNF-4). Akira Kimura, Atsushi Nishiyori, Takashi Mura- kami, Toshlro Tsukamoto, Shingo Hata, Takashi Osumi, Ry- oichi Okamura, Masataka Mori, and Masaki Takiguchi
HER2/Neu receptors by tyrphostins. Nir Osherou, Aviv Selective inhibition of the epidermal growth factor and
Gazit, Chaim Gilon, and Alexander Leuitzki
143 Preparation and characterization of a set of deoxyoli- gonucleotide 49-mers containing site-specific cis- syn, trans-syn-I, (6-4), and Dewar photoproducts of
John-Stephen Taylor thymidylyl(3' 4 5')-thymidine. Colin A. Smith and
152 N-Linked glycosylation of the ligand-binding domain of the human urokinase receptor contributes to the affinity for its ligand. Lisbeth Birk Mdler, Juri Polliinen, Ebbe RBnne, Nina Pedersen, and Francesco B h i
11160 Cis-active elements controlling lung cell-specific expression of human pulmonary surfactant protein B gene. Robert J . Bohinski, Jacquelyn A. Huffman, Jeffrey A. Whitsett, and Dauid L. Luttier
iv
11167
11172
11176
11188
11193
11199
11208
11217
11222
11230
11239
11247
11256
11265
11272
11278
11283
11290
Insulin stimulates association of insulin receptor sub- strate-1 with the protein abundant Src homology/
Koozi Matuoka, Hiroyuki Tammoto, Kohjiro Ueki, Yasushi growth factor receptor-bound protein 2. Kazuyuki Tobe,
Kaburagi, Shohji Ami, Tetsuya Noguchi, Michiyuki Mat- suda, Shinya Tanaka, Seisuke Hattori, Yasuhisa Fukui, Yasuo Akanumn, Yoshio Yazaki, Tadaomi Takenawa, and Taknshi Kadowaki
Comparative analysis of two alternative first exons reported for the mouse osteopontin gene. Elke I . Behrend, Ann F. Chambers, Sylvia M. Wilson, and David T. Denhardt
phorylation of kinesin light chains modulate kinesin Calmodulin binding to and CAMP-dependent phos-
ATPase activity. Heinrich J . G. Matthies, Richard J . Miller, and H. Clive Palfrey
Characterization of the receptor-binding domain of tet- anus toxin. Jane L. Halpern and Anne Loftus
Purification and characterization of an autophosphor- ylation-activated protein serine threonine kinase that phosphorylates and inactivates protein phosphatase 2A. Hong Guo, Shrikanth A. G. Reddy, and Zahi Damuni
A novel RNA polymerase 111 transcription factor frac-
gio Dieci, Laura Duimio, Federico Coda-Zabetta, Karen U. tion that is not required for template commitment. Gior-
Sprague, and Simone Ottonella
Functional erythropoietin receptor of the cells with neural characteristics. Comparison with receptor prop- erties of erythroid cells. Seiji Masuda, Masaya Nqao, Kyoya Takahata, Yoshihiro Konishi, Ferenc Gallyas, Jr., Tak- eshi Tabira, and Ryuzo Sasaki
Human glyoxalase 1. cDNA cloning, expression, and sequence similarity to glyoxalase I from Pseudomonas putida. Nam-Soon Kim, Yuri Umezawa, Satoshi Ohmura, and Seishi Kato
A mutational analysis of the polypyrimidine tract of introns. Effects of sequence differences in pyrimidine tracts on splicing. Robert F. Roscigno, Michael Weiner, and Mariano A. Garcia-Blanco
Tocotrienols regulate cholesterol production in mam- malian cells by post-transcriptional suppression of 3-
A. Parker, Bradley C. Pearce, Ronald W. Clark, David A. hydroxy-3-methylglutaryl-coenzyme A reductase. Rex
Gordon, and J. J. Kim Wright
trihydroxy nor-bile acids as new major biotransfor- 6@-Hydroxylation by the liver. Identification of 3,6,7-
dents. Claua‘io D. Schteingart, t e e R. Hctgey, Kenneth D. R. mation products of 3,7-dihydroxy nor-bile acids in ro-
Setchell, and Alan F. Hofmann
Phosphorylation weakens DNA binding by peptides containing multiple “SPKK” sequences. George R. Green, Hyuck-Jin Lee, and Dominic L. Poccia
Insulin stimulates serine and tyrosine phosphorylation in the juxtamembrane region of the insulin receptor.
A. Wilden, Xino Jian Sun, C. Ronald Kahn, and Morris F. Edward P. Feener, Jonathan M. Backer, George L. King, Peter
White
Fate of DNA targeted to the liver by asialoglycoprotein
sistence in cytoplasmic vesicles after partial hepatec- receptor-mediated endocytosis in vivo. Prolonged per-
tomy. Namita Roy Chowdhury, Catherine H. Wu, George Y.
Roy Chowdhury Wu, Purna C. Yemeni, Vasudeva R. Bommineni, and Jayanta
Antibodies to the extracellular receptor domain restore
the mutant insulin receptor valine 382. Christine Lebrun, the hormone-insensitive kinase and conformation of
Vkronique Baron, Perla Kaliman, Nadine Gautier, Jacqueline Dolais-Kitabgi, S i m o n Taylor, Domenico Accili, and Emman- uel Van Obberghen
Symmetrical disulfide bonds are not necessary for as- sembly and secretion of human fibrinongen. Jian-Zhong Zhang, Bohdan Kudryk, and Colvin M. Redman
Janet S. van Adelsberg, John C. Edwards, and Qais Al-Awqati The apical C1/HCOs exchanger of @ intercalated cells.
Arachidonic acid-selective cytosolic phospholipase A2 is crucial in the cytotoxic action of tumor necrosis
Sayumi Shibamoto, Takamitsu Hori, Naoto Oku, Fumiaki Ito, factor. Makio Hayakawa, Nobuhiro Ishida, Kenji Takeuchi,
and Masafumt Tsujimoto
11296
11304
11312
11321
11326
11335
11340
11348
11356
11364
11372
11380
11389
11394
11401
11409
11417
11426
Cloning and characterization of a putative Caa+m+ an- tiporter gene from Emherichia coli upon functional complementation of Na+/H+ antiporter-deficient strains by the overexpressed gene. D. Mack h e y , Arthur A. Guf- fanti, Jennifer Zemsky, Elhanan Pinner, Rachel Karpel, Etana Padan, Shtmon Schuldtner, and Terry A. Krulwich
Protein kinase A (PKA) still activates CFTR chloride
phosphorylation sites. Xiu-Bao Chang, Joseph A. Tabchar- channel after mutagenesis of all 10 PKA consensus
ani, Yue-Xian Hou, Timothy J . Jensen, Norbert Kartner, Noa Alan, John W. Hanrahan, and John R. Riordan
cludes two protein-binding sites in the promoter region. Structure of the canine pancreatic colipase gene in-
Shin-lchi Fukuoka, Dong-Er Zhang, Yukio Taniguchi, and George A . Scheele
Protein kinase C activates chloride conductance in C127 cells stably expressing the cystic fibrosis gene. Maria Cristina Dechecchi, Anna Tamanini, Giorgio Berton, and Giulio Cabrini
Molecular analysis of the essential gene for adenylate
pombe. Manfred Konrad kinase from the fission yeast Schizosaccharomyces
FK-606-binding protein: three-dimensional structure of the complex with the antagonist L-685,818. Joseph
Chan, Alice I. Marcy, Greg Wiederrecht, Jeffrey D. Hermes, W. Becker, Jennifer Rotonda, Brian M. McKeeuer, H. Karen
and James P. Springer
basolateral membrane domain of Madin-Darby canine The aZA-adrenergic receptor is targeted directly to the
kidney cells independent of coupling to pertussis toxin- sensitive GTP-binding proteins. Jeffrey R. Keefer and Lee E. Limbird
Three-dimensional structures of the periplasmic lysine/
ligand. Byung-Ha Oh, Jayuardhan Pundit, Chul-Hee Kang, arginine/ornithine-binding protein with and without a
Kishiko Nikaido, Sabiha Gokcen, Giovanna Ferro-Luzzi Ames, and Sung-Hou Kim
Sequence and functional characterization of a third
pressed in pancreatic islets, kidney, gastrointestinal inositol trisphosphate receptor subtype, IP3R-3, ex-
tract, and other tissues. Olivier Blondel, Jun Takeda, Heil- wig Janssen, Susumu Seino, and Graeme I. Bell
Mapping regions of yeast transcription factor IIIA re- quired for DNA binding, interaction with transcription
and Jacqueline Segall factor IIIC, and transcription activity. Catherine A. Milne
A closely linked complex of mouse mast cell-specific chymase genes on chromosome 14. Michael F. Gurish, Joseph H. Nadeau, Kenneth R. Johnson, H. Patrick McNeil, Kathleen M. Grattan, K. Frank Austen, and Richard L. Stevens
Oxidoreductive regulation of nuclear factor K B. In- volvement of a cellular reducing catalyst thioredoxin. Takumn Hayashi, Yoshw Ueno, and Taknshi Okamoto
High mobility group proteins 14 and 17 can space nu- cleosomes in vitro. David John Tremethick and Horace R. Drew
P-selectin is acylated with palmitic acid and stearic
Fujimoto, Eric Stroud, Ralph E. Whatley, Stephen M. Prescott, acid at cysteine 766 through a thioester linkage. Tetsuro
Laszlo Muszbek, Michael Laposata, and Rodger P. McEver
Inside-out integrin signaling in macrophages. Analysis of the role of the a6AB1 and a6BBl integrin variants in laminin adhesion by cDNA expression in an a6 in- tegrin-deficient macrophage cell line. Leslie M. Show, Margaret M. Lotz, and Arthur M. Mercurio
Translational repression of endogenous thymidine ki- nase mRNA in differentiating and arresting mouse cells. Martin KrGfler, Christian Waltner, Erhard Wintersber- ger, and Ernst W. Miillner
Major photoaffinity drug labeling sites for iodoaryl azidoprazosin in P-glycoprotein are within, or imme- diately C-terminal to, transmembrane domains 6 and 12. Lee M. Greenberger
Regulatory sequences on the human villin gene trigger the expression of a reporter gene in a differentiating
quilt%-Merino, Daniel Louuard, and Eric Pringault HT29 intestinal cell line. Sylvie Robine, Christian Sahu-
V
11435 Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEKl and MEK2. C h - F e n g Zheng and Kun-Liang G u m
11440 Organization and promoter activity of the mouse syn-
E. Neumann, Robert Kokenyesi, and Merton Bernfield decan-1 gene. Michael T. Hinkes, Olga A. Goldberger, Paul
11449 Aldehyde dehydrogenase-derived R-crystallins of squid
Zinoukua, Stanlsluu I. Tomarev, and Joram Piatigorsky and octopus. Specialization for lens expression. R i m D.
11456 Mouse procathepsin L lacking a functional glycosyla- tion site is properly folded, stable, and secreted by NIH 3T3 cells. Susan E. Kane
11463 Se uences in the 3’-untranslated region of the human c e l h r glutathione peroxid- gene are necessary and sufficient for selenocysteine mcorporatlon at the UGA codon. Qichang Shen, Fong-Fong Chu, and Peter E. Newburger
11470 The terminal quinol oxidasp of Bacillus subtilis have different energy conservation properties. Mark0 Lau- roeus and M&ten Wzkstrom
ADDITIONS AND CORRECTIONS 11474 Overexpression in Escherichia coli and affinity puri-
fication of chick kidney ferredoxin. Vol. 268 (1993) 6069-5076. Chilung Tang and Helen L. Henry
11474 Cuticle surface proteins of wild t e and mutant Cae- norhabditis elegans. Vol. 268 ( 1 9 8 ) 6600-6609. Mark L. Blarter
xi Cumulative author index. Numbers 1 through 16.
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Vol. 268, No. 15 The Journal of Biological Chemistry May 25,1993
CONTENTS Arranged by Subject Categories
MINIREVIEW 10946 Acetyl-coA carboxylase from yeast is an essential en- zyme and is regulated by factors that control phospho- lipid metabolism. Meinhard HaBlacher, Andreas S. luessa,
10701 Oligonucleotide x-ray structures in the study of confor- mation and interactions of nucleic acids. Olga Kennard and Stephen A. Salisbury Fritz Paltauf, and Sepp D. Kohlwein
10754
10938
11002
11239
10721
10780
10789
10808
10820
10863
10876
10888
10914
10920
10927
10932
CARBOHYDRATES, LIPIDS, AND OTHER NATURAL PRODUCTS
Phospholipase C-71 associates with viral and cellular 8rc kinases. Osamu Nakanishi, Futoshi Shibasaki, Michihiro Hidaka, Yoshimi Homma, and Tadaomi Takenawa
Mannosamine inhibits the synthesis of putative glyco- inositol phospholipid anchor precursors in mammalian cells without incorporating into an accumulated inter- mediate. Daniel Seuleuer and Terrane L. Rosenberry
Purification and characterization of farnesyl diphos- phate/geranylgeranyl diphosphate synthase. A ther- mostable bifunctional enzyme from Methanobacterium thermoautotrophicum. Anjun Chen and C. Dale Poulter
trihydroxy nor-bile acids as new major biotransfor- 5B-Hydroxylation by the liver. Identification of 3,5,7-
mation products of 3,7-dihydroxy nor-bile acids in ro- dents. Claudw D. Schteingart, Lee R. Hagey, Kenneth D. R. Setchell, and Alan F. Hofmann
CELL BIOLOGY AND METABOLISM G ~ s and G , selectively associate with the cloned so- matostatin receptor subtype SSTR2. Susan F. Law, Ka- zuki Yasuda, Graeme I. Bell, and Terry Reisine
Divergent regulation of phosphatidylinositol 3-kinase
Reif, Ivan Gout, Michael D. Waterfield, and Doreen A. Cantrell P86a and P858 isoforms upon T cell activation. Karin
cellular ATP via suppression of arachidonate metabo- Stimulation of aged human lung fibroblasts by extra-
lism. Ning-na Huang, Ding-ji Wang, and Leon A. Heppel
Cyclic GMP modulates depletion-activated Ca2+ entry in pancreatic acinar cells. Tristram D. Bahmon, Stephen J . Pandol, and Vincent E. Dianne
Effects of brefeldin A and accessory proteins on asso- ciation of ADP-ribosylation factors 1, 3, and 5 with Golgi. Su-Chen Tsai, Ronald Adamik, Randy S. Haun, Joel Moss, and Martha Vaughan
with mouse epithelin precursor from a highly tumori- Purification of an autocrine growth factor homologous
genic cell line. Jiun Zhou, Guang Gm, John W. Crabb, and Ginette Serrero
Calcium ionophore-induced transient down-regulation of c-myb mRNA levels in Friend erythroleukemia cells. And& Schaefer, Ulrich Stocker, and Hans Marquardt
Interaction of phosphofructokinase with tubulin and microtubules. Quantitative evaluation of the mutual effects. Attila Lehotzky, Marianna Telegdi, Karoly Liliom, and Judit Oucidi
Interaction of GTPase activating proteins (GAPS) with p21'" measured by a novel fluorescence anisotropy method. Essential role of Arg-903 of GAP in activation of GTP hydrolysis on p21'". Geoffrey G. Brownbridge, Peter N. Lowe, Keith J . M. Moore, Richard H. Skinner, and Martin R. Webb
Structure-function analysis of the Bcl-2 oncoprotein. Addition of a heterologous transmembrane domain to portions of the Bcl-2B protein restores function as a regulator of cell survival. Shigeki Tanaka, Koichi Saito, and John C. Reed
protein kinase inhibitor of CAMP-dependent protein Evidence for two additional isoforms of the endogenous
kinase in mouse. Marc0 A. Scarpetta and Michael D. Uhler
A novel protein domain required for apoptosis. Muta- tional analysis of human Fas antigen. Nmto Itoh and Shigekazu Nagata
10983
10990
10997
11057
11065
11097
11105
11113
11134
11167
11176
11188
11208
11230
11256
Transient transfection studies of secretion in bovine chromaffin cells and PC12 cells. Generation of kainate- sensitive chromaffin cells. Peter F. Wick, Ruth A. Senter, Leslie A. Parsek, Michael D. Uhler, and Ronald W. Holz
Regulation of linkages between the erythrocyte mem- brane and its skeleton by 2,3-diphosphoglycerate. Ryu- ichi Moriyama, Christian R. Lombardo, Ryan F. Workman, and Philip S. Low
Ca2+-dependent kinase and phosphatase control inositol 1,4,5-trisphosphate-mediated Ca2+ release. Modifica- tion by agonist stimulation. Bin-Xiun Zhang, Hong Z h , and Shmuel Muallem
Botulinum toxin inhibits arachidonic acid release as-
Prabhati Ray, Jonathan D. Berman, Wilbert Middleton, and sociated with acetylcholine release from PC12 cells.
James Brendle
Regulation by membrane potential of phosphatidyl-
Aidan G. M. Dauison, and Monica L. Prugue inositol hydrolysis in pancreatic islets. Trevor J . Biden,
Topography of glycosylation and UDP-xylose produc- tion. Ann E. Kearns, Barbara M. Vertel, and Nancy B. Schwartz
Xylosylation is an endoplasmic reticulum to Golgi event. Barbara M. Vertel, Linda M. Walters, Nina Flay, Ann E. Kearns, and Nancy B. Schwartz
Saccharomyces cereuisiae CDC25(1028-1589) is a guanine nucleotide releasing factor for mammalian Ras
Marie-Christine Cheuallier-Multon, Fabien Schweighoffer, proteins and is oncogenic in NIH3T3 cells.
Isabelle Barlat, Nicole Baudouy, Isabelle Fath, Marc Duchesne, and Bruno Tocqui
HER2/Neu receptors by tyrphostins. Nir Osherou, Auiu Selective inhibition of the epidermal growth factor and
Gazit, Chaim Gilon, and Alexander Leuitzki
Insulin stimulates association of insulin receptor sub- strate-1 with the protein abundant Src homology/ growth factor receptor-bound protein 2. Kazuyuki Tobe, Koozi Matuoka, Hiroyuki Tamemoto, Kohjiro Ueki, Yasushi Kaburagi, Shohji Asai, Tetsuya Noguchi, Michiyuki Mat- suda, Shinya Tanaka, Seisuke Hattori, Yasuhisa Fukui, Yasuo Akanuma, Yoshio Yazaki, Tadmmi Takenawa, and Takashi Kadowaki
Calmodulin binding to and CAMP-dependent phos- phorylation of kinesin light chains modulate kinesin ATPase activity. Heinrich J. G. Matthies, Richard J. Miller, and H. Cliue Palfrey
Characterization of the receptor-binding domain of tet- anus toxin. Jane L. Halpern and Anne Loftus
Functional erythropoietin receptor of the cells with neural characteristics. Comparison with receptor prop- erties of erythroid cells. Seiji Masuda, Masaya Nagm, Kyoya Tahhata, Yoshihiro Konishi, Ferenc Gallyas, Jr., Tak- eshi Tabira, and Ryuzo Sasaki
Tocotrienols regulate cholesterol production in mam-
hydroxy-3-methylglutaryl-coenzyme A reductase. Rex malian cells by post-transcriptional suppression of 3-
A. Parker, Bradley C. Pearce, Ronald W. Clark, David A. Gordon, and J . J . Kim Wright
Insulin stimulates serine and tyrosine phosphorylation in the juxtamembrane region of the insulin receptor. Edward P. Feener, Jonathan M. Backer, George L. King, Peter A. Wilden, Xiao Jian Sun, C. Ronald Kahn, and Morris F. White
vi
vii
11265
11272
.1
.1
.1
283
290
340
11401
11435
-10709
'10713
-10717
10746
10826
10842
10870
10961
11079
11090
11193
Fate of DNA targeted to the liver by asialoglycoprotein receptor-mediated endocytosis in vivo. Prolonged per- sistence in cytoplasmic vesicles after partial hepatec- tomy. Namita Roy Chowdhury, Catherine H. Wu, George Y.
Roy Chowdhury Wu, Purna C. Yerneni, Vasudeva R. Bommineni, and Jayanta
Antibodies to the extracellular receptor domain restore the hormone-insensitive kinase and conformation of the mutant insulin receptor valine 382. Christine Lebrun, Vkronique Baron, Perla Kalimon, Nadjne Gautier, Jacqueline Doluis-Kitabgi, S i m o n Taylor, Domenzco Accrlr, and Emman- uel Van Obberghen
The apical Cl/HCOs exchanger of B intercalated cells. Janet S. van Adekberg, John C. Edwards, and Qais AI-Awqati
Arachidonic acid-selective cytosolic phospholipase AZ is crucial in the cytotoxic action of tumor necrosis factor. Makio Hayakawa, Nobuhim Ishida, Kenji Takeuchi,
and Masafumi Tsujimoto Sayumi Shibamoto, Taknmitsu Hori, Naoto Oku, Fumiaki Ita,
basolateral membrane domain of Madin-Darby canine The aoA-adrenergic receptor is targeted directly to the
kidney cells independent of coupling to pertussis toxin- sensitive GTP-binding proteins. Jeffrey R. Keefer and Lee E. Limbird
Inside-out integrin signaling in macrophages. Analysis of the role of the a6M1 and a6BB1 integrin variants in laminin adhesion by cDNA expression in an (16 in- tegrin-deficient macrophage cell line. Leslie M. Shaw, Margaret M. Lotz, and Arthur M. Mercurm
Cloning and characterization of two distinct human extracellular signal-regulated kinase activator
Kun-Liang Guan kinases, MEKl and MEK2. Chao-Feng Zheng and
ENZYMOLOGY A novel functional target for tumor-promoting phorbol esters and lysophosphatidic acid. The p2lrac-CTPase activating protein n-chimaerin. Sohail Ahmed, Joel Lee, Robert Kozma, Anthony Best, Clinton Monfries, and Louis Lim
The active site substrate specificity of the CAMP-
Mendelow, Jaya Sriniuasan, Tae Ryong Lee, Scott Pluskey, dependent protein kinase. Young-Guen Kwon, Marianne
Allen Salerno, and Dauid S. Lawrence
A new isoform of 1 18-hydroxysteroid dehydrogenase
Naray-Fejes-Toth in aldosterone target cells. Erzsebet Rusvai and Aniko
Alanine dehydrogenase from soybean nodule bacter- oids. Kinetic mechanism and pH studies. Mark T. Smith and David W. Emerich
Differential usage of the carboxyl-terminal region among aldolase isozymes. Luc Berthiaume, Dean R. Tolan, and Jurgen Sygcmh
coded by TOL plasmid pWW0. A member of the zinc- Kinetic studies on benzyl alcohol dehydrogenase en-
Jeffrey P. Show, Monique Rekik, Franpise Schwager, and containing long chain alcohol dehydrogenase family.
Shigeaki Harayama
Rat liver imidase. Yuh-Shyong Yang, Sengoda Ramaswamy, and William B. Jakoby
Cap+ binding to sarcoplasmic reticulum ATPase revis-
route mechanism. Vincent Forge, Elisabeth Mintz, and Flo- ited. 11. Equilibrium and kinetic evidence for a two-
rent Guillain
Sterol 27-hydroxylase in bile acid biosynthesis. Mech- anism of oxidation of S&cholestane-3a,7a,l2a,27-te- trol into 3a,7a,l2a-trihydroxy-5j3-cholestanoic acid. Ingrid Holmberg-Betsholtz, Erik L u d , Ingemar Bjorkhem, and Kjell Wikvoll
Circular dichroism studies of diethyl pyrocarbonate- modified histidine in hen egg white lysozyme. Chingwen Li, Dexter S. Moore, and Robert C. Rosenberg
Purification and characterization of an autophosphor- ylation-activated protein serine threonine kinase that phosphorylates and inactivates protein phosphatase 2A. Hong G w , Shrikanth A. G. Reddy, and Zahi Damuni
11217
10802
10836
10906
10953
11 086
11296
11304
11321
11417
11470
N
10739
10796
10813
1085 1
10977
11008
11018
Human glyoxalase I. cDNA cloning, expression, and sequence similarity to glyoxalase I from Pseudomonas putida. Nam-Soon Kim, Yuri Umezawa, Satoshi Ohmura, and Seishi Kat0
MEMBRANES AND BIOENERGETICS Functional size analysis of F-ATPase from Escherichia coli by radiation inactivation. Jing R a n Ma, Jia Jiu Wu, Chi Meng Tzeng, and Rong Long Pan
Selective induction by phenobarbital of the electrogenic transport of glutathione and organic anions in rat liver canalicular membrane vesicles. Jose Carlos Fernan- dez-Checa, Murad Ookhtens, and Neil Kaplowitz
Vitamin E recycling in human erythrocyte membranes. Anastasia Constantinescu, Derick Han, and Lester Packer
Ca2+ binding to sarcoplasmic reticulum ATPase revis- ited. I. Mechanism of affinity and cooperativity modu- lation by H+ and M8+. Vincent Forge, Elisabeth Mintz, and Florent Guillain
Mutants of the Bacillus subtilis multidrug transporter Bmr with altered sensitivity to the antihypertensive
Alexander A. Neyfakh, and Shimon Schuldiner alkaloid reserpine. Maqbool Ahmed, Carina M. Borsch,
Cloning and characterization of a putative Ca*+/H+ an-
complementation of Na+/H+ antiporter-deficient strains tiporter gene from Escherichia coli upon functional
fanti, Jennifer Zemsky, Elhanan Pinner, Rachel Karpel, Etana by the overexpressed gene. D. Mack hey , Arthur A. Guf-
Padan, Shimon Schuldiner, and Terry A. Kruluxch
Protein kinase A (PKA) still activates CFTR chloride
phosphorylation sites. Xiu-Bao Chang, Joseph A. Tabchar- channel after mutagenesis of all 10 PKA consensus
Alon, John W. Hanrahun, and John R. Rwrdan ani, Yue-Xian Hou, Timothy J. Jensen, Norbert Kartner, Noa
Protein kinase C activates chloride conductance in C127 cells stably expressing the cystic fibrosis gene. Maria Cristina Dechecchi, Anna Tamanini, Gwrgio Berton, and Giulio Cabrini
Major photoaffinity drug labeling sites for iodoaryl azidoprazosin in P-glycoprotein are within, or imme- diately C-terminal to, transmembrane domains 6 and 12. Lee M. Greenberger
The terminal quinol oxidases of Bacillus subtilis have different energy conservation properties. Marko Luu- raeus and Miirten Wikstrom
IUCLEIC ACIDS, PROTEIN SYNTHESIS, AND MOLECULAR GENETICS
The two allele sequences of a common polymorphism in the promoter of the plasminogen activator inhibitor-1
HepG2 cells. Sally J. Dawson, Bjorn Wiman, Anders Ham- (PAI-1) gene respond differently to interleukin-1 in
sten, Fiona Green, Steve Humphries, and Adriano M. Henney
Cloning and characterization of complementary DNA encoding the eukaryotic initiation factor 2-associated 67-kDa protein (pa?). Shiyong Wu, Swati Gupta, Nabendu
Denslow, William C. Merrick, Debopam Chakrabarti, John C. Chatterjee, Ronald E. Hilemun, Terry G. Kinzy, Nancy D.
Osterman, and Naba K. Gupta
A novel cloning strategy reveals the gene for the yeast
Lefa E. Alksne and Jonathan R. Warner homologue to Escherichia coli ribosomal protein 512.
Characterization of RNA and DNA synthesis in Esch- erichia coli strains devoid of ppGpp. V. James Hernandez and Ham Bremer
Isolation and characterization of the human sprl gene and its regulation of expression by phorbol ester and cyclic AMP. Gang An, Johannes Tesfaigzi, Yue-Jen Chuu, and Reen W u
Functional interactions between SV40 T antigen and other replication proteins at the replication fork. Yota Murakami and Jerard Hurwitz
DNA polymerase (1 stimulates the ATP-dependent bind-
of replication. Yota Murakami and Jerard Hurwitz ing of simian virus tumor T antigen to the SV40 origin
Indicates a Communication
viii
11028 Mutational analysis of the human DNA polymerase a. The most conserved region in a-like DNA polymerases is involved in metal-specific catalysis. William C. Cope- land and Teresa s.-F. Wang
11041 Fidelity studies of the human DNA polymerase a. The most conserved region among a-like DNA polymerases is responsible for metal-induced infidelity in DNA syn- thesis. William C. Copeland, Naomi K. Lam, and Teresa S.-F. wang
11050 A human cDNA corresponding to a gene overexpressed during cell proliferation encodes a product sharing ho- mology with amoebic and bacterial proteins. Marie-Thirese Prospkri, Didier Ferbus, Isabelle Karczinski, and Girard Goubin
11125 Chicken ovalbumin upstream promoter-transcription factor (COUP-TF) represses transcription from the promoter of the gene for ornithine transcarbamylase in a manner antagonistic to hepatocyte nuclear factor-4 (HNF-4). Akira Kimura, Atsushi Nishiyori, Takashi Mura- kami, Toshiro Tsukamoto, Shingo Hata, T a b h i Osumi, Ry- oichi Okamura, Masataka Mori, and Masaki Takiguchi
11143 Preparation and characterization of a set of deoxyoli- gonucleotide 49-mers containing site-specific cis- syn, trans-syn-I, (6-4), and Dewar photoproducts of
John-Stephen Taylor thymidylyl(3’ + 6‘)-thymidine. Colin A. Smith and
11160 Cis-active elements controlling lung cell-specific expression of human pulmonary surfactant protein B gene. Robert J . Bohinski, Jacquelyn A. Huffman, Jeffrey A. Whitsett, and David L. Lattier
11172 Comparative analysis of two alternative first exons reported for the mouse osteopontin gene. Elke I. Behrend, Ann F. Chambers, Sylvia M. Wilson, and David T. Denhardt
11199
11222
11247
11312
11326
11356
11364
11372
11389
11409
11426
A novel RNA polymerase 111 transcription factor frac-
gw Dieci, Laura Duimw, Federico Coda-Zabetta, Karen U. tion that is not required for template commitment. Gior-
Sprague, and Simone Ottonello
A mutational analysis of the polypyrimidine tract of
tracts on splicing. Robert F. Roscigno, Mich~el Weiner, and introns. Effects of sequence differences in pyrimidine
Mariano A. Garcia-Blanc0
Phosphorylation weakens DNA binding by peptides containing multiple “SPKK” sequences. George R. Green, Hyuck-Jin Lee, and Dominic L. Poccia
cludes two protein-binding sites in the promoter region. Structure of the canine pancreatic colipase gene in-
George A. Scheele Shin-Ichi Fukuoka, Dong-Er Zhang, Yukw Taniguchi, and
Molecular analysis of the essential gene for adenylate
pornbe.. Manfred Konrad kinase from the fission yeast Schizosaccharomyces
Sequence and functional characterization of a third
pressed in pancreatic islets, kidney, gastrointestinal inositol trisphosphate receptor subtype, IP3R-3, ex-
tract, and other tissues. Olivier Blondel, Jun Takeda, Heil- wig Janssen, Susumu Seino, and Graeme I . Bell
Mapping regions of yeast transcription factor IIIA re- quired for DNA binding, interaction with transcription factor IIIC, and transcription activity. Catherine A. Milne and Jacqueline Segall
A closely linked complex of mouse mast cell-specific chymase genes on chromosome 14. Mich0el.F. Gurish, Joseph H. Nadeau, Kenneth R. Johnson, H. PatrEk McNeil, Kathleen M. Grattan, K. Frank Austen, and Richard L. Stevens
cleosomes in vitro. David John Tremethick and Horace R. High mobility group proteins 14 and 17 can space nu-
Drew
Translational repression of endogenous thymidine ki- nase mRNA in differentiating and arresting mouse cells. Martin Knhfler, Christian Waltner, Erhard Wintersber- ger, and Ernst W. Mullner
Regulatory sequences on the human villin gene trigger the expression of a reporter gene in a differentiating HT29 intestinal cell line. Sylvw Robine, Chrlstian Sahu- quillo-Merino, Daniel Louvard, and Eric Pringault
11440
11449
11456
11463
11474
-10705
10728
10760
10766
10773
10881
10895
10900
10969
.11 073
119
152
278
Organization and promoter activity of the mouse syn- decan-1 gene. Michael T. Hinkes, Olga A. Goldberger, Paul E. Neumnnn, Robert Kokenyesi, and Merton Bernfield
Aldehyde dehydrogenase-derived Q-crystallins of squid
Zinovieva, Stanislav I. Tomarev, and Joram Piatigorsky and octopus. Specialization for lens expression. R i m D.
Mouse procathepsin L lacking a functional glycosyla- tion site is properly folded, stable, and secreted by NIH 3T3 cells. Susan E. Kane
Sequences in the 3’-untranslated region of the human cellular glutathione peroxidase gene are necessary and sufficient for selenocysteine incorporation at the UGA codon. Qichang Shen, Fong-Fang Chu, and Peter E. Newburger
Overexpression in Escherichia coli and affinity puri- fication of chick kidney ferredoxin. Vol. 268 (1993) 5069-5076. Chilung Tang and Helen L. Henry
PROTEIN CHEMISTRY AND STRUCTURE Evaluation of mutagenesis for epitope mapping. Struc- ture of an antibody-protein antigen complex. Lata Pra- sad, Sadhuna Sharma, Margaret Vandonselaar, J . Wilson
Zbignww Dauter, and Louls T. J . Delbaere Quail,, Jeremy S. Lee, E. ,Bruce Waygoad, Keith S. Wilson,
Crystal structure of liganded and unliganded forms of bovine plasma retinol-binding protein. Giuseppe Zanotti, Rodolfo Berni, and Hugo L. Monaco
Refolding of luciferase subunits from urea and assem- bly of the active heterodimer. Evidence for folding intermediates that precede and follow the dimerization step on the pathway to the active form of the enzyme. Miriam M. Ziegler, Michel E. Goldberg, Alain F. Chaffotte, and Thomas 0. Baldwin
Contribution of folding steps involving the individual subunits of bacterial luciferase to the assembly of the active heterodimeric enzyme. Thomas 0. Baldwin, Miriam M. Ziegler, Alain F. Chaffotte, and Michel E. Goldberg
Folding of bacterial luciferase involves a non-native
tive enzyme and the unfolded subunits. A. Clay Clark, heterodimeric intermediate in equilibrium with the na-
James F. Sinclair, and Thomas 0. Baldwin
Mapping of nidogen binding sites for collagen type IV, heparan sulfate proteoglycan, and zinc. Dieter Reinhardt, Karlheinz Mann, Roswitha Nischt, Jay W. For, Man-Li Chu, Thomas Krieg, and Rupert Timpl
Identification of a novel subunit of the Type I inter- feron receptor localized to human chromosome 21. Oscar R. Colamonici and Paul Domanski
Structure-function studies of the human thyrotropin receptor. Inhibition of binding of labeled thyrotropin
C. Morris, Elizabeth R. Bergert, and Daniel J . McCormlck (TSH) by synthetic human TSH receptor peptides: John
tional domains of chicken gizzard smooth muscle cal- Binding and regulatory properties of expressed func-
desmon. Charles S. Redwood and Steven B. Marston
Characterization of glycoprotein I1 from bovine adre-
components representing the secretory vesicle counter- nal medullary chromaffin granules. Identification of
parts of the lysosomal-associated membrane glycopro- teins (lamp-1 and lamp-2). A. David Hieber and David L. Chrktie
A role for cholecystokinin-stimulated protein tyrosine phosphorylation in regulated secretion by the pan- creatic acinar cell. Manfred P. Lutz, Shari L. Sutor, Robert T. Abraham, and Laurence J. Miller
N-Linked glycosylation of the ligand-binding domain of the human urokinase receptor contributes to the affinity for its ligand. Lisbeth Birk Mdller, Jari Wllunen, Ebbe Rdnne, Nina Pedersen, and Francesco Blasi
Symmetrical disulfide bonds are not necessary for as- sembly and secretion of human fibrinongen. Jian-Zhong Zhang, Bohdan Kudryk, and Colvin M. Redmnn
Indicates a Communication
ix
11335 FK-606-binding protein: three-dimensional structure of the complex with the antagonist L-686,818. Joseph W. Becker, Jennifer Rotonda, Brian M. McKeever, H. Karen Chan, Alice I. Marcy, Greg Wiederrecht, Jeffrey D. Hermes, and James P. Springer
11348 Three-dimensional structures of the periplasmic lysine/ arginine/ornithine-binding protein with and without a ligand. Byung-Ha Oh, Jayvardhun Pandit, Chul-Hee Kang, Kishiko Nikaido, Sabihu Gokcen, Gwvannu Ferro-Luzzi Ames, and Sung-Hou Kim
11380 Oxidoreductive regulation of nuclear factor K B. In- volvement of a cellular reducing catalyst thioredoxin. Takuma Hayashi, Yoshio Ueno, and Takoshi Okamoto
11394 P-selectin is acylated with palmitic acid and stearic
Fujimoto, Eric Stroud, Ralph E. Whatley, Stephen M. Prescott, acid at cysteine 766 through a thioester linkage. Tetsuro
Laszlo Muszbek, Michael Laposata, and Rodger P. McEver
11474 Cuticle surface proteins of wild type and mutant Cae- norhabditis elegans. Vol. 268 (1993) 6600-6609. Mark L. Bluxter
Abraham, Robert T., 11119
Adamik, Ronald, 10820 Accili, Domenico, 11272
Ahmed, Maqbool, 11086 Ahmed, Sohail, 10709 Akanuma, Yasuo, 11167 Al-Awqati, Qais, 11283 Alksne, Lefa E., 10813 Alon, Noa, 11304 Ames, Giovanna Ferro-Luzzi,
An, Gang, 10977 A d , Shohji, 11167 Austen, K. Frank, 11372 Backer, Jonathan M., 11256
Baldwin, Thomas O., 10760, Bahnson, Tristram D., 10808
Barlat, Isabelle, 11113 Baron, VBronique, 11272 Baudouy, Nicole, 11113 Becker, Joseph W., 11335 Behrend, Elke I., 11172
Bergert, Elizabeth R., 10900 Bell, Graeme I., 10721,11356
Berman, Jonathan D., 11057 Bernfield, Merton, 11440 Berni, Rodolfo, 10728 Berthiaume, Luc, 10826 Berton, Giorgio, 11321 Beat, Anthony, 10709 Biden, Trevor J., 11065 Bjorkhem, Ingemar, 11079
Blaxter, Mark L., 11474 Blasi, Francesco, 11152
Blondel, Olivier, 11356 Bohinski, Robert J., 11160 Bommineni, Vasudeva R.,
Borsch, Carina M., 11086 Bremer, Hans, 10851
Brownbridge, Geoffrey G., Brendle, James, 11057
Cabrini, Giulio, 11321 Cantrell, Doreen A., 10780 Chaffotte, Alain F., 10760,
Chakrabarti, Debopam, 10796 Chambers, Ann F., 11 172 Chan, H. Karen, 11335 Chang, Xiu-Bao, 11304 Chattejee, Nabendu, 10796 Chen, Anjun, 11002 Chevallier-Multon.
11348
10766,10773
11265
10914
10766
Chowdhury, Jayanta Roy, Marie-Christine: 11113
11265 Chowdhury, Namita Roy, 11265
Christie, David L., 11073
Chu, Mon-Li, 10881 Chu, Fong-Fong, 11463
Chuu, Yue-Jen, 10977 Clark, A. Clay, 10773
Coda-Zabetta, Federico, Clark, Ronald W., 11230
Colamonici, Oscar R., 10895 11199
Constantinescu, Anastasia,
Copeland, William C., 11028,
Crabb, John W., 10863
10906
11041
Damuni, Zahi, 11193 Dauter, Zbigniew, 10705 Davison, Aidan G. M., 11065
Dechecchi, Maria Cristina, Dawson, Sally J., 10739
Delbaere, Louis T. J., 10705 Denhardt, David T., 11172 Denslow, Nancy D., 10796 Dieci, Giorgio, 11199 Dionne, Vincent E., 10808 Dolais-Kitabgi, Jacqueline,
Domanski, Paul, 10895 Drew, Horace R., 11389
Duimio, Laura, 11199 Duchesne, Marc, 11113
Emerich, David W., 10746 Edwards, John C., 11283
Feener, Edward P., 11256 Fath, Isabelle, 11113
Ferbus, Didier, 11050 Fernhndez-Checa, J o d
Carlos, 10836 Flay, Nina, 11 105 Forge, Vincent, 10953,10961 Fox, Jay W., 10881 Fujimoto, Tetsuro, 11394 Fukui, Yasuhisa, 11167 Fukuoka, Shin-Ichi, 11312
Gallyas, Ferenc, Jr., 11208
Garcia-Blanco, Mariano A., Gao, Guang, 10863
Gautier, Nadine, 11272 Gazit, Aviv, 11134 Gilon, Chaim, 11134 Gokcen, Sabiha, 11348 Goldberg, Michel E., 10760,
Goldberger, Olga A,, 11440 Gordon, David A., 11230 Goubin, GBrard, 11050 Gout, Ivan, 10780 Grattan, Kathleen M., 11372 Green, Fiona, 10739 Green, George R., 11247
Guan, Kun-Liang, 11435 Greenberger, Lee M., 11417
Guffanti, Arthur A., 11296 Guillain, Florent, 10953,
Guo, Hong, 11193
Gupta, Swati, 10796 Gupta, Naba K., 10796
Gurish, Michael F., 11372 Hagey, Lee R., 11239 HaBlacher, Meinhard, 10946 Halpern, Jane L., 11188
Han, Derick, 10906 Hamsten, Anders, 10739
Hanrahan, John W., 11304
11321
11272
11222
10766
10961
AUTHOR INDEX
Hata, Shingo, 11125 Harayama, Shigeaki, 10842
Hattori, Seisuke, 11167 Haun, Randy S., 10820 Hayakawa, Makio, 11290 Hayashi, Takuma, 11380 Henney, Adriano M., 10739 Henry, Helen L., 11474 Heppel, Leon A., 10789 Hermes, Jeffrey D., 11335 Hernandez, V. James, 10851 Hidaka, Michihiro, 10754 Hieber, A. David, 11073
Hinkes, Michael T., 11440 Hileman, Ronald E., 10796
Hofmann, Alan F., 11239 Holmberg-Betsholtz, Ingrid,
Holz, Ronald W., 10983
Hori, Takamitsu, 11290 Homma, Yoshimi, 10754
Hou, Yue-Xian, 11304 Huang, Ning-na, 10789 Huffman, Jacquelyn A.,
Humphries, Steve, 10739 Hurwitz, Jerard, 11008,11018 Ishida, Nobuhiro, 11290 Ito, Fumiaki, 11290 Itoh, Naoto, 10932 Ivessa, Andreas S., 10946 hey, D. Mack, 11296 Jakoby, William B., 10870 Janssen, Heilwig, 11356 Jensen, Timothy J., 11304 Johnson, Kenneth R., 11372 Kaburagi, Yasushi, 11167 Kadowaki, Takashi, 11167 Kahn, C. Ronald, 11256 Kaliman, Perla, 11272 Kane, Susan E., 11456 Kang, Chul-Hee, 11348
Karczinski, Isabelle, 11050 Kaplowitz, Neil, 10836
Karpel, Rachel, 11296
Kato, Seisbi, 11217 Kartner, Norbert, 11304
Kearns, Ann E., 11097, 11105 Keefer, Jeffrey R., 11340 Kennard, Olga, 10701 Kim, Nam-Soon, 11217 Kim, Sung-Hou, 11348 Kimura, Akira, 11125
Kinzy, Terry G., 10796 King, George L., 11256
Knofler, Martin, 11409
Kokenyesi, Robert, 11440 Kohlwein, Sepp D., 10946
Konishi, Yoshihiro, 11208 Konrad, Manfred, 11326 Kozma, Robert, 10709 Krieg, Thomas, 10881 Krulwich, Terry A., 11296
Kwon, Young-Guen, 10713 Kudryk, Bohdan, 11278
Lam, Naomi K., 11041 Laposata, Michael, 11394 Lattier, David L., 11160
11079
11160
Lauraeus, Marko, 11470
Lawrence, David S., 10713 Law, Susan F., 10721
Lee, Hyuck-Jin, 11247 Lebrun, Christine, 11272
Lee, Jeremy S., 10705 Lee, Joel, 10709 Lee, Tae Ryong, 10713 Lehotzky, Attila, 10888 Levitzki, Alexander, 11134 Li, Chingwen, 11090 Liliom, Karoly, 10888 Lim, Louis, 10709
Loftus, Anne, 11188 Limbird, Lee E., 11340
Lombardo, Christian R.,
Lotz, Margaret M., 11401 Louvard, Daniel, 11426 Low, Philip S., 10990 Lowe, Peter N., 10914 Lund, Erik, 11079 Lutz, Manfred P., 11119 Ma, Jing Tyan, 10802 Mann, Karlheinz, 10881 Marcy, Alice I., 11335 Marquardt, Hans, 10876 Marston, Steven B., 10969 Masuda, Seiji, 11208 Matsuda, Michiyuki, 11167 Matthies, Heinrich J. G.,
Matuoka, Koozi, 11167
McEver, Rodger P., 11394 McCormick, Daniel J., 10900
McKeever, Brian M., 11335 McNeil, H. Patrick, 11372 Mendelow, Marianne, 10713 Mercurio, Arthur M., 11401 Merrick, William C., 10796 Middleton, Wilbert, 11057 Miller, Laurence J., 11119 Miller, Richard J., 11176
Mintz, Elisabeth, 10953, Milne, Catherine A., 11364
Mdler, Lisbeth Birk, 11152
Monfries, Clinton, 10709 Monaco, Hugo L., 10728
Moore, Keith J. M., 10914 Moore, Dexter S., 11090
Mori, Masataka, 11125 Moriyama, Ryuichi, 10990 Morris, John C., 10900 Moss, Joel, 10820 Muallem, Shmuel, 10997 Mullner, Ernst W., 11409 Murakami, Takashi, 11125 Murakami, Yota, 11008,
Muszbek, Laszlo, 11394 Nadeau, Joseph H., 11372 Nagao, Masaya, 11208
Nakanishi, Osamu, 10754 Nagata, Shigekazu, 10932
Niray-Fejes-Tbth, Anik6,
Neumann, Paul E., 11440 Newburger, Peter E., 11463
10990
11176
10961
11018
10717
Neyfakh, Alexander A., 11086 Nikaido, Kishiko, 11348 Nischt, Roswitha, 10881 Nishiyori, Atsushi, 11125 Noguchi, Tetsuya, 11167 Oh, Byung-Ha, 11348 Ohmura, Satoshi, 11217
Okamura, Ryoichi, 11125 Okamoto, Takashi, 11380
Ookhtens, Murad, 10836 Oku, Naoto, 11290
Osherov, Nir, 11134 Osterman, John C., 10796 Osumi, Takashi, 11125 Ottonello, Simone, 11199 Ovadi, Judit, 10888
Packer, Lester, 10906 Padan, Etana, 11296 Palfrey, H. Clive, 11176 Paltauf, Fritz, 10946 Pan, Rong Long, 10802 Pandit, Jayvardhan, 11348 Pandol, Stephen J., 10808 Parker, Rex A., 11230 Parsels, Leslie A,, 10983 Pearce, Bradley C., 11230 Pedersen, Nina, 11152 Piatigorsky, Joram, 11449 Pinner, Elhanan, 11296 Pluskey, Scott, 10713 Poccia, Dominic L., 11247 Polliinen, Jari, 11152 Poulter, C. Dale, 11002 Prasad, Lata, 10705 Prescott, Stephen M., 11394 Pringault, Eric, 11426 Prospki, Marie-ThBrhse,
Prugue, Monica L., 11065 Quail, J. Wilson, 10705
Ramaswamy, Sengoda, 10870 Ray, Prabhati, 11057 Reddy, Shrikanth A. G.,
Redman, Colvin M., 11278
Reed, John C., 10920 Redwood, Charles S., 10969
Reinhardt, Dieter, 10881 Reif, Karin, 10780
Reisine, Terry, 10721
Riordan, John R., 11304 Rekik, Monique, 10842
Robine, Sylvie, 11426 Rdnne, Ebbe, 11152
Rosenberg, Robert C., 11090 Roscigno, Robert F., 11222
Rosenberrv, Terrone L..
11050
11193
Rotonda, Jennifer, 11335 Rusvai, Erzsebet, 10717
10938
Sahuquillo-Merino, Christian, 11426
Saito, Koichi, 10920
Salisbury, Stephen A,, 10701 Salerno, Allen, 10713
Sasaki, Ryuzo, 11208 Scarpetta, Marco A,, 10927