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The New England Journal of Medicine Downloaded from nejm.org at BROWN UNIVERSITY on April 20, 2013. For personal use only. No other uses without permission.
Copyright © 1993 Massachusetts Medical Society. All rights reserved.
The New England Journal of Medicine Downloaded from nejm.org at BROWN UNIVERSITY on April 20, 2013. For personal use only. No other uses without permission.
Copyright © 1993 Massachusetts Medical Society. All rights reserved.
The New England Journal of Medicine Downloaded from nejm.org at BROWN UNIVERSITY on April 20, 2013. For personal use only. No other uses without permission.
Copyright © 1993 Massachusetts Medical Society. All rights reserved.
The New England Journal of Medicine Downloaded from nejm.org at BROWN UNIVERSITY on April 20, 2013. For personal use only. No other uses without permission.
Copyright © 1993 Massachusetts Medical Society. All rights reserved.
The New England Journal of Medicine Downloaded from nejm.org at BROWN UNIVERSITY on April 20, 2013. For personal use only. No other uses without permission.
Copyright © 1993 Massachusetts Medical Society. All rights reserved.