Viral And Parasitic Pulmonary Manifestations In HIV And Pulmonary Neoplasia In HIV DR. KOMALDEEP JR PULMONARY MED TBHP VIRUSESPARASITES CYTOMEGALOVIRUS CMVTOXOPLASMA INFLUENZASTRONGYLOIDES ADENOVIRUSCRYPTOSPORIDIUM HERPES SIMPLEXMICROSPORIDIA VARICELLA ZOSTER RSV CYTOMEGALOVIRUS CMV Complex DNA virus - B- group of the family Herpesviridae. It is the largest virus that infects the humans. Production of characteristics enlarged cells. Establishes latency - polymorphonuclear cells, T lymphocytes & salivary glands Once infected, an individual probably carries CMV for life. The infection usually remains latent. CMV REACTIVATION In the general population, the proportion of people with evidence of previous CMV infection range from 40% to 100%, depending on ethnicity and country of residence. CMV reactivation develop frequently when T-lymphocytes mediated immunity is compromised, for e.g. organ transplant, lymphoid neoplasm, acquired immunodeficiencies. Clinically significant HIV related CMV infection is associated with severe immunosuppresion, CD4