Chapter 14. Scott Chilton. 1997. Genetic engineering of plant secondary metabolism for insect protection. Pages 237-269. In: Nadine Carozzi, Michael Koziel (editors). 1997. Advances in Insect Control: the Role of Transgenic Plants. London, UK, Taylor & Francis Ltd., 301 pages.

Keywords: nicotine, cotinine, anabasine, nicotine toxicity, insect resistance mechanism, nicotine biosynthesis, intermediates and enzymes, ornithine, putrescine, arginine, agmatine, n-methyl-putrescine, n-methyl-pyrrolidinium, nicotinic acid, transgenic modification of nicotine synthesis, cyanogenic glucosides and glucosinolates, cyanogenic glucosides, prunasin, dhurrin, linamarin,

lotastralin, release of hydrogen cyanide at the wound site, toxicity of hydrogen cyanide, glucosinolates, sinigrin allyl-GS, sinalbin, homologous series of methylthioalkyl-GS, glunicobrassicin indolylmethyl-GS, alkylisothiocyanate release at the wound site, cyanogenic glucoside biosynthesis, the glucosinolate biosynthetic pathway, mechanistic heterogeneity of glucosinolate pathway committing enzymes, an engineered glucosinolate-cyanogenic glucoside hybrid pathway, cyclic hydroxamic acids (DIBOA and DIMBOA), storage, release and decomposition of DIMBOA, defensive role against insects, fungi, and bacteria, biosynthesis of DIMBOA, DIMBOA pathway genes, pyrethrin, insect toxicity and resistance, biosynthesis of chrysanthemic and pyrethric acids, biosynthesis of rethrolones and pyrethrins, rotenone, toxicity of rotenone, biosynthesis of rotenone, unsaturated amides, pellitorine, spilanthol, neoherculin, toxicity, prospects for crop protection by unsaturated amides