Focus Diagnostics offers a

diverse menu of IFA and

ELISA kits.

This brochure features a

practical illustrated guide to

our vector-borne products.

Beginning with laboratory testing services for infectious diseases more

than 30 years ago, Focus Diagnostics scientists continue to collaborate

with leading researchers and health agencies worldwide to develop and

manufacture high quality serological test kits for many emerging and endemic

vector-borne diseases.

The information contained in this brochure is a summary of the vector-borne

disease products that Focus Diagnostics offers.

Vector-Borne Diseases

DISEASE PATHOGEN VECTOR CLINICAL SYNDROME(S) DISTRIBUTION DIAGNOSTIC PRODUCT

West Nile EncephalitisWest Nile Fever

West Nile VirusFlavivirus

Mosquito(Culex spp.)

CNS infection Fever, headache, body ache

US, spreading nationwide; Canada;Africa; Asia

EL0300G CE West Nile Virus IgG DxSelect™ EL0300M CE West Nile Virus IgM Capture DxSelect™

96-well ELISA plateProducts are FDA cleared.

Dengue FeverDengue Hemorrhagic Fever

Dengue VirusFlavivirus

Mosquito(Aedes aegypti)

Severe headache, joint & muscle pain, rash; also hemorrhagic fever

Tropical regions world wide: Africa, Asia, China, India, Middle East, South & Central America, Caribbean, Australia, South & Central Pacific

EL1500G CE Dengue Virus ELISA IgG DxSelect™EL1500M CE Dengue Virus IgM Capture DxSelect™

96-well ELISA plate. DFV Types 1-4

Eastern Equine Encephalitis (EEE)Eastern Equine Encephalitis VirusAlphavirus

Mosquito(Culiseta melanura)

CNS infectionEastern US, Central & South America, Caribbean

IF0300G Arbovirus IFA IgG KitIF0300M Arbovirus IFA IgM Kit

80 tests (ten 8-well slides)

4 spots/well: EEE, CE, SLE, WEEProducts are FDA cleared.

California Encephalitis (CE)(syn. La Crosse Encephalitis)

La Crosse Encephalitis VirusBunyavirus

Mosquito(Aedes triseriatus)

CNS infectionUS – Upper Midwestern & Appalachian region

St. Louis Encephalitis (SLE)St. Louis Encephalitis VirusFlavivirus

Mosquito(Culex spp.)

CNS infection East-central US, Central & South America

Western Equine Encephalitis (WEE)Western Equine Encephalitis VirusAlphavirus

Mosquito(Culex spp.)

CNS infection Western US, Central & South America

BabesiosisBabesia microtiProtozoan parasite

Deer Tick(Ixodes spp.)

Red blood cell infection – hemolytic anemia; acute respiratory distress syndrome

US – Primarily Northeastern;rarely Pacific states; rare in Europe

IF0904 Babesia (B. microti) IFA Substrate Slide

10 wells/slide

Anaplasmosis(HGA)

Anaplasma phagocytophilumBacteria

Deer Tick(Ixodes spp.)

White blood cells: granulocytes.Leukopenia, anemia

Europe; US-Northeast, Upper Midwest, Northern California

IF1450G CE Anaplasma phagocytophilum IFA IgG KitIF1450M CE Anaplasma phagocytophilum IFA IgM Kit120 tests (ten 12-well slides)

Human Monocytic Ehrlichiosis(HME)

Ehrlichia chaffeensisBacteria

Lone Star Tick(Amblyomma americanum)

White blood cells: monocytes.Leukopenia, anemia

Southeast & South-central US; possibly Southern Europe

IF1003 Ehrlichia chaffeensis IFA IgG Substrate SlideIF1004 Ehrlichia chaffeensis IFA IgM Substrate Slide

120 tests (ten 12-well slides)

Mediterranean Spotted Fever(syn, Boutonneuse Fever)

Rickettsia conoriiBacteria

Dog Tick(Rhipicephalus sanguineus)

Fever, purpuric rash, ‘tache noire’, organ involvement

Europe; Africa; Central AsiaIF0104 CE Rickettsia conorii IFA Substrate Slide

8 wells/slide

Rocky Mountain Spotted FeverRickettsia rickettsiiBacteria

Dog Tick, Wood Tick(Dermacentor spp.)

Fever, rash; damage to organs and tissues North, Central and South AmericaIF0100G CE Rickettsia IFA IgG KitIF0100M CE Rickettsia IFA IgM Kit

80 tests (ten 8-well slides)

2 spots/well: R. rickettsii and R. typhiProducts are FDA cleared.

Murine typhusRickettsia typhiBacteria

Rat Flea(Xenopsylla cheopis)

Remittent fever, headache, rashUrban cities and coastal ports worldwide where rats are abundant

Q FeverCoxiella burnettiBacteria

Airborne (inhaled);Also Tick-borne

Severe illness, including fever, pneumonia, hepatitis

Worldwide, primarily rural areas (sheep, cattle, goats)

IF0200G CE Q Fever IFA IgG KitIF0200M CE Q Fever IFA IgM Kit

80 tests (ten 8-well slides)

2 spots/well: Coxiella burnetti phase I and II Products are FDA cleared.

Vector-Borne Diseases

Diagnostic Products for Vector-Borne Diseases

Test kits contain necessary reagents required to perform the assays. Refer to product catalog for the complete listing of test kits and substrate slides.

Focus Diagnostics offers serology kits for other zoonotic pathogens including bartonella, hantavirus, and leptospirosis.

Vector-Borne Disease IFA Guide

The images shown below are photomicrographs of positive IFA results on slides tested

at Focus Diagnostics. Actual results may vary depending on patient samples tested and

microscope optics.

Cypress, California 90630 USA www.focusdx.com

© Focus Diagnostics, Inc., 2013. All rights reserved. DXVBI0713

Learn more about our products on our Web site: www.focusdx.com

For additional information contact Focus Diagnostics Customer Service at:

1-562-240-6500 or fax 1-562-240-6510.

Arbovirus IFA

Babesia IFAQ Fever IFA

Rickettsia IFA

Vector-Borne Diseases

LITERATURE FOR DISTRIBUTION OUTSIDE THE USA ONLY

Focus Diagnostics, DxSelect, and the associated logos are the trademarks of Quest Diagnostics.