Vaccine Research SAAD

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  • 8/13/2019 Vaccine Research SAAD

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    There has been some friendly dialogue and healthy debate on Facebook recently

    regarding the very contentious issue of childhood vaccines; focused mostly on the

    safety of vaccines. Childhood vaccinations can easily become a very divisive issuewhich has the potential to damage relationships as each side (pro and anti vax) dig

    their heals in and become ever more convinced of the veracity of their position (and

    the patent falsehood of the other position). My personal opinion on childhood

    vaccinations is that parents need to do their own research and that this research needs

    to be based on a variety of sources:

    1. What public health officials tell us, as well as the medical profession(established guidelines, information on government websites, information

    from your GP or Pediatrician)

    2. Published research in scientific journals that sheds light upon issues of vaccinesafety and efficacy

    3. Anecdote and personal experience of family, friends as well as from socialmedia

    Combining these three sources, an intelligent individual is able to reach some

    reasonable conclusion about how to proceed on the issue. Three choices face parents

    based on their research:

    1. All vaccines listed on the schedule have a high level of safety and efficacy. Allthe vaccines target illnesses that are potentially life-threatening/disabling and

    could not be adequately treated with other means. The vaccine schedule, as set

    out by public health authorities (e.g. NSW Health), is the one to follow as is

    (no changes).

    2. Some of the vaccines on the schedule have questionable safety and/or efficacy

    or the diseases they target are low prevalence and/or not life threatening or achild has such a low risk of contracting the disease, that the risks of vaccines

    adverse effects outweigh the benefits, that they can be reasonably excluded

    from my childs schedule of shots. Parent proceeds with an alternative

    schedule, in cooperation with their doctor, omitting certain shots (e.g. MMR,

    Heb B) and/or changing the spacing of when the shots are given (e.g. avoiding

    multiple shots in one doctor visit spacing them out more to reduce the

    chances of and to monitor for adverse effects)

    3. The entire schedule is not suitable for my child and the vaccines, as a whole,are probably unsafe and the risk of adverse effects is too high. Parents in this

    camp may have already had a vaccine injured child or have a history of

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    autoimmune disorders in their family (read on to see the burgeoning scientific

    literature on the causal link between certain vaccines and autoimmunity).

    What I aim to demonstrate here is not that vaccines are dangerous and should betotally avoided. Rather, I aim to demonstrate that there is more than sufficient

    scientific evidence to move many parents well away from position number one (total

    acceptance of what public health authorities state, following the vaccines schedule as

    is, and a move toward positions two or three). Unfortunately, and this is based on my

    personal experience, most parents who are entrenched in position number one have

    honestly not taken the time to access and read the group 2 evidence (published

    science), and largely rely upon evidences groups 1 and 3 (what public health

    authorities tell them and anecdote). This creates an atmosphere where healthy debate

    is exceedingly difficult.

    Let me now take you through just some of the published science, that I believe wouldtip any reasonable individual, toward position 2 or 3. I will set out my argument

    according to the following headings, and back each one with published data.

    1. Historical is it true that vaccines were a decisive factor in the eradication orreducing the prevalence of some of our worst communicable diseases?

    Historical evidence compiled in the recently published book, Dissolving Illusions -

    Disease, Vaccines, and the Forgotten History, by Suzanne Humphries MD, provides

    compelling evidence that much of what vaccines are credited for doing was actually

    the result of better hygiene, sanitation and accurate medical diagnosis. The book isfilled with documented evidence, fully referenced with archival data. Here is just one

    example from Dr Humphries meticulously researched book.

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    Dont be scared away by this busy graph. Each colour represent the death ratefor a

    particular disease. The point illustrated is quite straightforward. For each of these

    diseases, the death rate had already greatly reduced beforethe vaccine for the disease

    was introduced. The measles vaccines, introduced in 1968/1969, came well after the

    mortality rates from measles had plummeted. You can clearly see that for all these

    diseases, you had massive mortality rates in the 1800s which then greatly reduces wellbefore each of the vaccines were introduced. If you read Humphries book, you will be

    shocked at the level of poor hygiene, poor sanitation and people living in filth at this

    time in Britain as well as America. With no proper sanitation, people living in slums,

    no access to fresh food, any disease would overwhelm such a weakened immune

    system. Bottom line mortality rates had significantly dropped well before vaccines

    were introduced.

    2. Documented lack of efficacy of vaccines and lack of long-term protection outbreaks occur in populations with high vaccination rates (as opposed to

    media scares about measles and whooping cough, that convince parentsunvaccinated children are to blame).

    Scientific references documented outbreaks of disease in populations with very high

    rates of vaccination for the disease.

    California whooping cough epidemic in 2010 most children who got the whooping

    cough were completely vaccinated, as were the adolescents.

    http://www.ncbi.nlm.nih.gov/pubmed/22819634

    Measles outbreak in highly vaccinated high school population 99% were vaccinated

    and 95% had antibodies to measles after vaccination

    http://www.ncbi.nlm.nih.gov/pubmed/3821823

    And another measles outbreak in a school with 92% vaccination rate almost half the

    cases of measles were in students who had received two doses of the measles vaccine

    http://cid.oxfordjournals.org/content/early/2012/05/23/cid.cis445.full

    And another

    http://www.ncbi.nlm.nih.gov/pubmed/17609829

    And anotherhttp://www.jpeds.com/article/S0022-3476(05)80726-7/abstract

    And another showing vaccines do not confer long-lasting immunity

    http://www.ncbi.nlm.nih.gov/pubmed/8118532

    And another, this time in a population who had received THREE doses of the

    whooping cough vaccine We conclude that pertussis remains a significant health problem in Nova Scotia, despite nearly universalvaccinationhttp://www.jpeds.com/article/S0022-3476(89)80643-2/abstract

    And anothermeasles outbreak in population with 99% vaccination

    coverageIncomplete vaccination coverage is not a valid explanation for the Quebec City measles outbreak.

    http://www.ncbi.nlm.nih.gov/pubmed/1884314

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    3. Vaccine adjuvants (usually aluminium) can be neurotoxic to the developingbrain and have a documented link to triggering autoimmune disorders,

    including lupus, arthritis and Type 1 diabetes. The Hepatitis B vaccine seems

    to crop up often in the literature as a documented causal link and this is the

    vaccine that is first given to all newborns. Links to each study are provided

    below the title of the study.

    Aluminium Vaccine adjuvants: Are they Safe?

    http://www.ingentaconnect.com/content/ben/cmc/2011/00000018/00000017/art00011

    Aluminum is an experimentally demonstrated neurotoxin and the most commonly usedvaccine adjuvant. Despite almost 90 years of widespread use of aluminum adjuvants,medical science's understanding about their mechanisms of action is still remarkablypoor.There is also a concerning scarcity of data on toxicology and pharmacokineticsof these compounds. In spite of this, the notion that aluminum in vaccines is safeappears to be widely accepted. Experimental research, however, clearly shows thataluminum adjuvants have a potential to induce serious immunological disorders in

    humans. In particular, aluminum in adjuvant form carries a risk for autoimmunity, long-term brain inflammation and associated neurological complications and may thus haveprofound and widespread adverse health consequences.In our opinion, the possibilitythat vaccine benefits may have been overrated and the risk of potential adverse effectsunderestimated, has not been rigorously evaluated in the medical and scientific community.We hope that the present paper will provide a framework for a much needed and longoverdue assessment of this highly contentious medical issue.

    Hepatitis B vaccine induces apoptotic death in Hepa1-6 cells

    http://www.ncbi.nlm.nih.gov/pubmed/22249285Vaccines can have adverse side-effects, and these are predominantly associated with

    the inclusion of chemical additives such as aluminum hydroxide adjuvant Weconclude that exposure of Hepa1-6 cells to a low dose of adjuvanted hepatitis Bvaccine leads to loss of mitochondrial integrity, apoptosis induction, and cell death

    Vaccinations may induce diabetes-related autoantibodies in one-year-old children.

    http://www.ncbi.nlm.nih.gov/pubmed/14679101

    The spectrum of ASIA: Autoimmune (Auto-inflammatory) Syndrome induced by

    Adjuvants

    http://lup.sagepub.com/content/21/2/118.short

    Autoimmunity following Hepatitis B vaccine as part of the spectrum of Autoimmune

    (Auto-inflammatory) Syndrome induced by Adjuvants (ASIA): analysis of 93 cases

    http://lup.sagepub.com/content/21/2/146.short

    Rubella Vaccine causal link to chronic joint disease

    http://onlinelibrary.wiley.com/doi/10.1002/art.1780390913/abstractThe Program and the US Court of Federal Claims have accepted a causal relationship between currently used rubella vaccine in the US and some chronicarthropathy with an onset between 1 week and 6 weeks after vaccine administration.

    Hep B vaccine and increased risk of multiple sclerosis

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    http://www.neurology.org/content/63/5/838.shortThese findings are consistent with the hypothesis that immunization with the recombinant hepatitis B vaccine is associated with an increasedrisk of MS, and challenge the idea that the relation between hepatitis B vaccination and risk of MS is well understood.

    Mechanisms of aluminum adjuvant toxicity and autoimmunity in pediatric

    populations. (Published in the journal Lupus in 2012)

    http://www.ncbi.nlm.nih.gov/pubmed/22235057

    In summary, research evidence shows that increasing concerns about current vaccination

    practices may indeed be warranted. Because children may be most at risk of vaccine-induced

    complications, a rigorous evaluation of the vaccine-related adverse health impacts in the

    pediatric population is urgently needed.

    A case-control study of serious autoimmune adverse events following hepatitis B

    immunization.

    http://www.ncbi.nlm.nih.gov/pubmed/16206512

    Aluminum in the central nervous system (CNS): toxicity in humans and animals,

    vaccine adjuvants, and autoimmunity.Publishedin Immunological Research, 2013.

    http://www.ncbi.nlm.nih.gov/pubmed/23609067

    We have examined the neurotoxicity of aluminum in humans and animals under various

    conditions, following different routes of administration, and provide an overview of the various

    associated disease states. The literature demonstrates clearly negative impacts of

    aluminum on the nervous system across the age span. In adults, aluminum exposure

    can lead to apparently age-related neurological deficits resembling Alzheimer's andhas been linked to this disease and to the Guamanian variant, ALS-PDC. Similar

    outcomes have been found in animal models.In addition, injection of aluminum adjuvants

    in an attempt to model Gulf War syndrome and associated neurological deficits leads to an

    ALS phenotype in young male mice. In young children, a highly significant correlation

    exists between the number of pediatric aluminum-adjuvanted vaccines administered

    and the rate of autism spectrum disorders. Many of the features of aluminum-induced

    neurotoxicity may arise, in part, from autoimmune reactions, as part of the ASIA

    syndrome.