1
Purpose: We assessed the efficacy of laparoscopy in removal of difficult ureteral stones. Materials and Methods: We attempted laparoscopic removal of difficult ureteral stones in 16 patients (10 males and 6 females). We used transperitoneal ap- proach. 9 patients had proximal and 7 patients had middle or distal ureteral stones. Our criteria for selecting the pa- tient for laparoscopic treatment were large size ( 1cm) of stone or failing in treatment with SWL or intracorporeal lithotripsy. We used 3 (for proximal ure- teral stones) or 4 (for distal ureteral stones) trocars. Results: Transperitoneal laparoscopic ure- terolithotomy was successful in all of our 16 patients. Operative time ranged from 2.4 to 4.5 hours (mean 3.2 hours). Hospi- tal stay ranged from 3 to 14 days (mean 6.3 days). All patients were stone-free on post-operative KUB. Only in 3 patients complication (prolonged urinary leak) oc- curred and one of these needed open sur- gery for closing the ureteral incision. Fol- low-up IVP was performed in 10 patients and stone residue or ureteral obstruction was not found in anyone. Conclusion: Based on our experience, transpertioneal laparoscopic ureterolithot- omy is a safe practical alternative for open surgery in patients with large ureteral stones or when less invasive procedures fail to treat the stone. V-02.09 Potency- and continence preserving radical cystectomy with hemiprostatectomy Wolf M, Wunderlich H, Schubert J Friedrich-Schiller-University, Dept. of Urology, Jena, Germany Introduction: Radical cystectomy has been the gold standard for treatment of muscle invasive bladder cancer. However, this kind of therapy may have an impact on quality of life, including sexual-, uri- nary and social function. For this reason we performed prostate sparing surgery during radical cystectomy for invasive bladder cancer. Materials and Methods: Between De- cember 2003 and December 2005 34 pa- tients with a mean age of 63.2 years un- derwent radical cystectomy with hemiprostatectomy due to bladder cancer. Preoperative evaluation included a normal digital rectal examination, PSA lower than 4 ng/ml and an inconspicuous transrectal ultrasound. All patients underwent pros- tate biopsy preoperatively. Surgery con- sisted of radical cystectomy, hemiprostate- ctomy and resection of the prostate adenoma in the lower part of prostate as well as regional lymphadenectomy. The follow-up was 1-24 months. Results: Postoperative pathological stage was pTis in 2 patients, pTa in 1, pT1 in 5, pT2 in 20 and pT3 in 6 cases. Except of 7 patients no patient had a deterioration of sexual function. 30 pa- tients were fully continent during day- time and nighttime. The mean operation time was 225 minutes ( 42 minutes, ranged 167-370 minutes). Mean opera- tive blood loss was 499 ml ( 255 ml, ranged 100-1000ml). Conclusion: Radical cystectomy with prostate sparing surgery in patients with invasive bladder cancer allowed preserv- ing the external urethral sphincter and the neurovascular bundles. It is abso- lutely necessary that this procedure is restricted to highly selected patients, especially without concomitant prostate cancer. V-02.10 Laparoscopic radical cystoprostatectomy (LRC) Pen ˜a J, Prera A, Gonzalez J, Hannaoui N, Vicente E, Garcia D, Abad C, Prats J Servicio de Urologı ´a, Hospital de Sa- badell, Corporacio ´ Sanitaria Parc Tauli, Sabadell, Spain Introduction: Laparoscopic surgery is in clear expansion in our country given that it has been shown a decrease of the mor- bidity associated to open surgery with at least the same oncological results. LRC as is shown in the video is a feasible and reproducible proceeding. Methods: We show a video of a LRC as is done in our centre. Bilateral pelvic limph node dissection is simultaneously done. Specimen is removed on block (cystopros- tatectomy and lymphadenectomy). We present the case of 87-year-old male diag- nosed by TUR of a pT2 G III transitional cell carcinoma with CT scan and bone scan negative for metastasis. Patient com- plained of gross haematuria and severe dysuria. We indicated a LRC with a bilat- eral cutaneous ureterostomy as urine di- version. Results: Postoperative evolution was cor- rect and he was discharged at day 6 of surgery. Ileous last 24 hours. Blood lost was minimum and no transfusion was re- quired. Surgery took four and a half hours. Conclusion: LRC is a feasible proceeding to be done by teams with previous experi- ence in laparoscopic surgery. In our expe- rience, initial learning curve has been shorter than the laparoscopic prostatec- tomy one. The chance of a LRC in elderly patients must be kept in mind. V-02.11 Photodynamic assisted detection and treatment of superficial bladder cancer using the photosensitizer Hexvix® Thomas K, Ray E, Murphy D, Chatterton K, Khan S, O’Brien T Guy’s and St Thomas’ NHS Foundation Trust, London, UK Introduction: Photodynamic assisted transurethral resection (TUR) of bladder tumour may improve completeness of tu- mour resection. More precise mapping of bladder cancer could translate into better outcomes. This video describes the tech- nique of photodynamic diagnosis (PDD) using Hexvix® in our unit. Patients and Methods: There are cur- rently 4 ongoing studies using the intra- vesical photosensitizer Hexvix® in our unit; 1) a randomised trial of photody- namic assisted TUR versus standard white light TUR for primary superficial bladder cancer; 2) check cystoscopy post BCG; 3) positive urine cytology/no evidence of disease; 3) multi-focal tumour recurrence. Patients are consented for participation in the appropriate study. The photosensitizer Hexvix® is instilled into the bladder on the ward at least 90minutes before the procedure. The D-Light system (Storz) is used for the cystoscopy as it allows a switch between white and blue light. Ini- tially a “white” light cystoscopy is per- formed and a bladder map obtained. Us- ing the same equipment a “blue” light cystoscopy is performed and any areas of fluorescence photographed and biopsied. Results: The photosensitizer Hexvix® is well tolerated with no complications to date. Visualisation and colour contrast be- tween fluorescent tumour and non-fluores- cent urothelium are excellent. The tech- nique and interpretation of fluorescence have been easily acquired. The presence and histology of lesions detected under white and blue light is being compared. Conclusion: The technique of photody- namic diagnosis using Hexvix® can be easily established in clinical practice and shows promise in detecting and treating superficial bladder cancer but results are awaited. VIDEO SESSIONS 206 UROLOGY 68 (Supplement 5A), November 2006

V-02.10: Laparoscopic radical cystoprostatectomy (LRC)

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Page 1: V-02.10: Laparoscopic radical cystoprostatectomy (LRC)

Purpose: We assessed the efficacy oflaparoscopy in removal of difficult ureteralstones.Materials and Methods: We attemptedlaparoscopic removal of difficult ureteralstones in 16 patients (10 males and 6females). We used transperitoneal ap-proach. 9 patients had proximal and 7patients had middle or distal ureteralstones. Our criteria for selecting the pa-tient for laparoscopic treatment werelarge size (� 1cm) of stone or failing intreatment with SWL or intracorporeallithotripsy. We used 3 (for proximal ure-teral stones) or 4 (for distal ureteralstones) trocars.Results: Transperitoneal laparoscopic ure-terolithotomy was successful in all of our16 patients. Operative time ranged from2.4 to 4.5 hours (mean 3.2 hours). Hospi-tal stay ranged from 3 to 14 days (mean6.3 days). All patients were stone-free onpost-operative KUB. Only in 3 patientscomplication (prolonged urinary leak) oc-curred and one of these needed open sur-gery for closing the ureteral incision. Fol-low-up IVP was performed in 10 patientsand stone residue or ureteral obstructionwas not found in anyone.Conclusion: Based on our experience,transpertioneal laparoscopic ureterolithot-omy is a safe practical alternative for opensurgery in patients with large ureteralstones or when less invasive proceduresfail to treat the stone.

V-02.09Potency- and continence preservingradical cystectomy withhemiprostatectomyWolf M, Wunderlich H, Schubert JFriedrich-Schiller-University, Dept. ofUrology, Jena, Germany

Introduction: Radical cystectomy hasbeen the gold standard for treatment ofmuscle invasive bladder cancer. However,this kind of therapy may have an impacton quality of life, including sexual-, uri-nary and social function. For this reasonwe performed prostate sparing surgeryduring radical cystectomy for invasivebladder cancer.Materials and Methods: Between De-cember 2003 and December 2005 34 pa-tients with a mean age of 63.2 years un-derwent radical cystectomy withhemiprostatectomy due to bladder cancer.Preoperative evaluation included a normaldigital rectal examination, PSA lower than4 ng/ml and an inconspicuous transrectalultrasound. All patients underwent pros-tate biopsy preoperatively. Surgery con-

sisted of radical cystectomy, hemiprostate-ctomy and resection of the prostateadenoma in the lower part of prostate aswell as regional lymphadenectomy. Thefollow-up was 1-24 months.Results: Postoperative pathologicalstage was pTis in 2 patients, pTa in 1,pT1 in 5, pT2 in 20 and pT3 in 6 cases.Except of 7 patients no patient had adeterioration of sexual function. 30 pa-tients were fully continent during day-time and nighttime. The mean operationtime was 225 minutes (� 42 minutes,ranged 167-370 minutes). Mean opera-tive blood loss was 499 ml (� 255 ml,ranged 100-1000ml).Conclusion: Radical cystectomy withprostate sparing surgery in patients withinvasive bladder cancer allowed preserv-ing the external urethral sphincter andthe neurovascular bundles. It is abso-lutely necessary that this procedure isrestricted to highly selected patients,especially without concomitant prostatecancer.

V-02.10Laparoscopic radicalcystoprostatectomy (LRC)Pena J, Prera A, Gonzalez J, Hannaoui N,Vicente E, Garcia D, Abad C, Prats JServicio de Urologıa, Hospital de Sa-badell, Corporacio Sanitaria Parc Tauli,Sabadell, Spain

Introduction: Laparoscopic surgery is inclear expansion in our country given thatit has been shown a decrease of the mor-bidity associated to open surgery with atleast the same oncological results. LRC asis shown in the video is a feasible andreproducible proceeding.Methods: We show a video of a LRC as isdone in our centre. Bilateral pelvic limphnode dissection is simultaneously done.Specimen is removed on block (cystopros-tatectomy and lymphadenectomy). Wepresent the case of 87-year-old male diag-nosed by TUR of a pT2 G III transitionalcell carcinoma with CT scan and bonescan negative for metastasis. Patient com-plained of gross haematuria and severedysuria. We indicated a LRC with a bilat-eral cutaneous ureterostomy as urine di-version.Results: Postoperative evolution was cor-rect and he was discharged at day 6 ofsurgery. Ileous last 24 hours. Blood lostwas minimum and no transfusion was re-quired. Surgery took four and a halfhours.Conclusion: LRC is a feasible proceedingto be done by teams with previous experi-

ence in laparoscopic surgery. In our expe-rience, initial learning curve has beenshorter than the laparoscopic prostatec-tomy one. The chance of a LRC in elderlypatients must be kept in mind.

V-02.11Photodynamic assisted detection andtreatment of superficial bladdercancer using the photosensitizerHexvix®Thomas K, Ray E, Murphy D, ChattertonK, Khan S, O’Brien TGuy’s and St Thomas’ NHS FoundationTrust, London, UK

Introduction: Photodynamic assistedtransurethral resection (TUR) of bladdertumour may improve completeness of tu-mour resection. More precise mapping ofbladder cancer could translate into betteroutcomes. This video describes the tech-nique of photodynamic diagnosis (PDD)using Hexvix® in our unit.Patients and Methods: There are cur-rently 4 ongoing studies using the intra-vesical photosensitizer Hexvix® in ourunit; 1) a randomised trial of photody-namic assisted TUR versus standard whitelight TUR for primary superficial bladdercancer; 2) check cystoscopy post BCG; 3)positive urine cytology/no evidence ofdisease; 3) multi-focal tumour recurrence.Patients are consented for participation inthe appropriate study. The photosensitizerHexvix® is instilled into the bladder onthe ward at least 90minutes before theprocedure. The D-Light system (Storz) isused for the cystoscopy as it allows aswitch between white and blue light. Ini-tially a “white” light cystoscopy is per-formed and a bladder map obtained. Us-ing the same equipment a “blue” lightcystoscopy is performed and any areas offluorescence photographed and biopsied.Results: The photosensitizer Hexvix® iswell tolerated with no complications todate. Visualisation and colour contrast be-tween fluorescent tumour and non-fluores-cent urothelium are excellent. The tech-nique and interpretation of fluorescencehave been easily acquired. The presenceand histology of lesions detected underwhite and blue light is being compared.Conclusion: The technique of photody-namic diagnosis using Hexvix® can beeasily established in clinical practice andshows promise in detecting and treatingsuperficial bladder cancer but results areawaited.

VIDEO SESSIONS

206 UROLOGY 68 (Supplement 5A), November 2006