2016 3 12

1) 2) 3) 

– – 

     

Acute gout

Chronic gout

Uric Acid

Monosodium urate crystal

Purine

-

• 

(Synovial fluid)

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≠ ≠

/

• • 

• 

• • 

( )

•  ! ( )• • 

( )

• –  : 40–  :

• – 

• – 

-

•  ( )• 

– – – – – 

-

•  ( )• • • 

–  (Intercritical Period)

• • • 

–  - (Tophi) – – – 

• • 

– – 

• – – – – 

• • •  ( / )

NSAIDs(Non-Steroidal Anti-Inflammtory Drugs)

– – – 

Ibuprofen

(Proton Pump Inhibitor)

(H2 Receptor Antagonist)

-2 (COX-2 inhibitors) – 

(Colchicine ) • 

– • 

– 

  

? ? 

/

/

• • • 

/

• • 

/

• –  (Allopurinol)–  (Febuxostat)

• –  (Probenecid–  (Benzbromarone)

/

•  (Allopurinol)– – – 

• – – 

•  (Febuxostat)

/

•  (Probenecid– –  ( )– 

• • 

/

•  /• 

– • 

– 

• – BMI: (kg) ÷ (m) ÷ (m)

²< 18 5

18.5 - 22.9 23 - 24.9

25 - 29.9 > 30

• • • • • 

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