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1- Rx Webs in plummer vinson : dilation 2- Rx Intimal flap of carotid artery: surgey 3- Rx Ant wall MI : risk of arterial thrombo ; full doses heparin + 3 months of warfarin. 04- Rx Acute ill and toxic pt wit h UC : proctosigmo + biopsy 5- Rx Heat stroke : rapid cooling and for shivering : CPZ & Diazepam 6- Rx progressive back pain + myelopathy: IV dexa --> MRI --> Rx Metastatic cord compression : Radiotherapy 7- Rx refractory hydrothorax due to cirrohis : TIPS 8- Rx Ref ascitis : TIPS 9- Rx recurrent variceal bleading not responsive to medical Rx : TIPS 10- Rx TCA poisoning : NaHCO3 11- Rx diabetic cystopathy: 1- oral bethancol , 2- intermittent catheter 12- Rx chlamydia : single dosde of Azithromycin OR 7 days doxycyclin 13- Rx neuromalignant syn : Dantrolene or Bromocripten 14- Rx atopic dermatitis : prevention of Rx , take short baths. 15- Rx presbyopia : convex lenses 16- Rx amblyopia : cover better eye 17- Rx hyperopia : convex lenses 18- Rx myopia : concave lenses 19- Rx beta blocker posioning : recent ingestion--> emesis , bradycardia : Atropine--> Isoproterenol--> glucagon-->pace 20- Rx beta blocker poisioning : severe bronchospasm : aminophylline or Beta2 agonist. 21- Rx Isolated duodenal hematoma : NG + parentral

USMLE Step 2 Treatment Notes

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USMLE Step 2 Notes on Treatment

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Page 1: USMLE Step 2 Treatment Notes

1- Rx Webs in plummer vinson : dilation

2- Rx Intimal flap of carotid artery: surgey

3- Rx Ant wall MI : risk of arterial thrombo ; full doses

heparin + 3 months of warfarin.

04- Rx Acute ill and toxic pt wit h UC : proctosigmo +

biopsy

5- Rx Heat stroke : rapid cooling and for shivering : CPZ &

Diazepam

6- Rx progressive back pain + myelopathy: IV dexa -->

MRI --> Rx Metastatic cord compression : Radiotherapy

7- Rx refractory hydrothorax due to cirrohis : TIPS

8- Rx Ref ascitis : TIPS

9- Rx recurrent variceal bleading not responsive to

medical Rx : TIPS

10- Rx TCA poisoning : NaHCO3

11- Rx diabetic cystopathy: 1- oral bethancol , 2-

intermittent catheter

12- Rx chlamydia : single dosde of Azithromycin OR 7

days doxycyclin

13- Rx neuromalignant syn : Dantrolene or Bromocripten

14- Rx atopic dermatitis : prevention of Rx , take short

baths.

15- Rx presbyopia : convex lenses

16- Rx amblyopia : cover better eye

17- Rx hyperopia : convex lenses

18- Rx myopia : concave lenses

19- Rx beta blocker posioning : recent ingestion-->

emesis , bradycardia : Atropine--> Isoproterenol-->

glucagon-->pace

20- Rx beta blocker poisioning : severe bronchospasm :

aminophylline or Beta2 agonist.

21- Rx Isolated duodenal hematoma : NG + parentral

Page 2: USMLE Step 2 Treatment Notes

nutrition.

22- Rx for preventing recurrence of HBV after liver

transplant : HBV Ig + Lamivudine.

23- Rx Seizure due to INH toxicity : Pyriodoxine

24- Rx hyponatremia due to SIADH : water restriction.

25- Rx Girl infant < 3 months w vaginal bleeding :

observation

26- Rx Slow down progression of DM nephropathy : AceI

27- Rx epiglottitis : Fiberoptic laryngoscopy in OR ( not in

ER )

28- Rx acute attacks of migrains : Rizatriptan

29- Rx acute attack of migrains lasts for longer than 48

hours or r frequently recurrent : ergotamine.

30- Rx anorexia nervosa : hospitalization

31- Rx prophlaxy against human bites : Amoxi /

calvulanate

32- Rx rhabdomyolysis : osmotic diuresis + bicarbonate

33- Rx Afib + HF : digoxin .

34- Rx acute rejection : high dose IV steroides.

35- Rx bipolar disorder : lithium , valporate,

OLANZAPINE.

36- Rx PCP : cotri .

37- Rx PCP + PaO2<70 mmhg: cotri + steroides.

38- Rx Bebesiosis : ( quinine, clinda) or ( atovaquone ,

azithro)

39- Rx IlleoIlleal intussuception due to HSP : Surgery ( in

contrast to other causes of intuss )

40- Rx esophagitis in HIV: itraconazole --> no answer -->

esophagoscopy + cytology + biopsy

41- Rx psuedotumor cerebri : 1-acetazolamide --> no

answer --> 2- shunt.

42- Rx struvite stones : eradication of UT infections.

Page 3: USMLE Step 2 Treatment Notes

43- Rx persistantly elevated ALT leval w detectable HBs

Ag , HBe Ag and HBV DNA : INF and lamivudine.

44- Rx febrile neutropenic pt : cetazidime or cefepime (

add vanco if pt is hypotensive or there is high suspiscion

of MRSA)

45- Rx Isolated systolic HTN: thiazides .

46- Rx acute attack of cluster headaches : 100% oxygen

47- Rx prevention of cluster headaches : verapamil

,pred,ergots,methysergide,Lithium

48- Rx reversing cardiac effects of ca channel blockers :

Ca!

49- Rx Viterous hemorrhage : immediate ophthlamo

consultation.

50- Rx Battery in esophagus : remove it immediatly .

51- Rx Battery in intestine : observe it.

52- Rx acute bleeding in pts with liver failure : FFP.

53- Rx OtoSclerosis : Surgery + Sodium Fluoride .

54- Rx non infalm comedones : topical retionides.

55- Rx mild inflam acne : benzoyl peroxide , topical

antibiotics.

56- Rx Refractory mania, severe dep , dep in pregnancy ,

neuroleptic malig synd, catatonic schizo : ECT

57- Rx Acute attack of hepatic encephalopathy : All

dietary protein withheld , oral or rectal lactulose , oral

NEOMYCIN.

58- Rx white reflex in infant : refer to ophthalmo

59- Rx ST elevation>1 mm in 2 contiguous leads / new

LBBB : thrombolytic therapy OR PTCA

60- Rx New LBBB : thrombolytic therapy.

61- Rx Trachoma : ORAL tetra or erythromycin.

62- Rx diabetic nephropathy : protein restriction ( 0.8

g/kg) , don't use AceI if Cr> 2,2.5

Page 4: USMLE Step 2 Treatment Notes

63- Rx Zenker : excision and frequently cricophayngeal

myotomy

64- Rx porcelain gall bladder : cholecystectomy ( risk of

carcinoma)

65- Rx conversion disorder : psychotherapy ( long term

benefit )

66- Rx Dyspepsia w positve breath test : erad H.pylori

67- Rx Dyspepsia w/o positive breath test : H2 blocker /

PPI

68- Rx fibromuscular dysplasia : percutaneous

angioplasty w stent placement.

69- Rx prophylaxis against MAC : Azithro or clarithro

70- Rx PBC: ursodeoxycholic

71- Rx Orbital cellulitis : imm admin of IV antibiotics.

72- Rx carcinoid synd : can u remove it?( Remove it ) , u

can't remove it ? ( use octerotide )

73- Rx vaginismus : relaxation, Kegel exercise , insertion

training.

74- Rx Hypertrophic dystrophy of Vulva : steroides.

75- Rx lichen scleroris : steroides

76- Rx atrophic vaginitis : estrogen

77- Rx stable angina + HTN : Beta blocker.

78- Rx Tremor and rigidity in parkinson : Antichol (

benzotropines)

79- Rx exercise induced asthma : Beta agon , mast cell

stabilizer.

80- Rx Reiter syn : NSAIDS .

81- Rx Chronic HCV ( HCV RNA presents , ALT inc ,

chornic hepatitis of at least moderate grade): INF+

Ribaverin.

82- Rx Lactation Suppression: tight fitting bra , ice packs

, analgesics.

Page 5: USMLE Step 2 Treatment Notes

83- Rx non-complinat schizophrenic pt : long acting

injectable antipsychotics like fluphenazine and

haloperidol.

84- Rx TIA due to atherosclrosis: ASA

85- Rx TIA due to emboli from heart : Anticoagulation.

86- Rx Nocardiosis : sulfonamides.

87- Rx prophylaxis of getting UTI after intercourse :

voiding after intercourse.

88- Rx met prostate cancer: palliative radiation + anti

androgen therapy ( leuprolide )

89- Rx Actinomycosis : high dose penicillin

90- Rx RA with erosive joint disease : DMARDS ( MTX,

hydroxychlorquine , sulfasalazine , etanercept, azathio)

91- Rx Met brain tumor : surgery + whole brain radiation.

92- Rx Dressker : NSAIDS --> no answer : short course of

steroides.

93- Rx PMR : low dose pred

94- Rx Giant cell : high dose.

95- Rx cocaine intox : Benzo + ASA + nitrates.

96- Rx effect of PEEP on CO : inotropic agent or fluids.

97- Rx RMSF: Doxycycline

98- Rx De Quervain’s tensosynovitis : Long acting

steroids.

99- Rx HSV encephalitis : IV acyclo without delay.

100- Rx ALS: Riluzole

101- Rx Subdural hematoma w/o midline shift : head

elevation , hyperventilation , acetazolamide

102- Rx Subdural hematoma w midline shift : craniotomy

103- Rx early syph : Single IM Benz Peni , if allergic Doxy

or tetra for 14 days . in pregnancy use peni with

desintizator

104- Rx Acute attack of Gout : use NSAIDs, there may be

Page 6: USMLE Step 2 Treatment Notes

an option of colchicine but do not mark this option.

105- Rx prevention of gout attack : allopurinol

106- Rx GAD: Buspirone

107- Rx post-term preg : NST + BPP ( twice/weekly ) „³

oligo or late dece or >43 w „³ delivery

108- Rx Kawasaki in children : ASA ( the only disease u

give child ASA inspite of fear of Reye syn)

109- Rx massive hemoptysis : RIGID broncho

110-Rx acute vaso-occlusive crisis in sicke cell :

Exchange transfusion aplastic crisis,splenic

sequestration,acute

chest syndrome, cva,priapism

111-Rx Acute dystonia : antihistamine or anticholinergic

112-Rx Parkinsonism as a result of antipsychotic: Benzo

113-Rx Akathesia : beta blockers

114-Rx HEAVY UNREMITTING ENDO HEMORRHAGE : high

dose conjugated estrogens

115-Rx Stress Fx : restricting weight bearing + short leg

casts (3 to 4 W)

116-Rx Met breast cancer + lytic bone disease : IV

pamidronate

117-Rx intertrochanteric Fx of femur : internal fix with

sliding screw and plate , early mobilization

118-Rx Cholangitis : Drain biliary tree with ERCP

119-Rx Lambert Eaton : plasmapheresis +

immunosuppression

120-Rx Emphysematous cholecystitis : Imm fluid +

electrolyte correction + antibiotics + early surgical

cholecystectomy

121-Rx Acute exacerbation of MS: Steroides

122-Rx Umblical hernia : mostly Observe ( look for few

indection of intervention)

Page 7: USMLE Step 2 Treatment Notes

123-Rx Cholestoma: surgical removal

124-Rx GBS: IVIg, plasmaphresis

125-Rx Hordeoulum/stye : warm compress„³ no answer

after 48 hours „³ incision and drainage

126-Rx Erysipelas : Peni

127-Rx Fever in neutropenic pt : Cetazidime / Cefepime

128-Rx MG crisis: plasmapheresis

129-Rx Sarcoidosis : systemic steroids.

130-Rx for prevention of recurrence of renal stone : know

them well and also remember that Ca intake must be

NORMAL or even INCREASED !!!???.

131-Rx Osgood Schlatter disease: Rest, NSAIDs , brief

casting

132-Rx Molluscum : curettage or application of luquid

nitrogens

133-Rx Amebic liver abscess: metro

134-Rx Hypochlo met alkalo : 0.9% Nacl , NG suction „³ K

supp

135-Rx Anorexia asso w chemotherapy : Megestro

acetate

136-Rx Tension pneumothorax : needle thoraco

137-Rx Sensory neuropathy w DM : TCA , Gabapentin ,

NSAIDs

138-Rx acute pyeloneph : IV ampi + genta ( empiric )

139-Rx VT hemo stable : Lido or Amio

140-Rx prevention of variceal bleeding : beta blocker

141-Rx pul infection if CF : aminoglyco + antipseudomona

142-Rx Hydatid cyst : Surgery under cover of

Albendazole ( Plz do not aspirate these cysts )

143-Rx Reflex sympathetic dystrophy: physical therapy,

prednisone , ganglion block

144-Rx Chorioamnionitis :Ampi+ Genta

Page 8: USMLE Step 2 Treatment Notes

145-Rx PCOD: combines estro/prog or cyclic prog

146-Rx Perforation of esophagus: primary closure of

esophagus , drainage of mediastinum w/i 6 hours to

prevent mediastinitis

147-Rx Rotator cuff tendonitis : Lido injection

148-Rx Megacolon: Iv fluids , Antibiotics , bowel rest , Iv

cortico

149-Rx Disseminated histoplasmosis in HIV: IV ampho B

+ LIFE LONG itraconazole

150-Rx Pseudomona : cefepim/ceftazidime

151-Rx Dystonia : Anti hista , anti chol

152-Rx AIDS with Dysphagia : 1-2 w of oral fluconazole

„³ no answer „³ biopsy

153-Rx Vipoma : correct dehydration slow diarrhea

surgery

154-Rx Ewing’s sarcoma : radio/chemo surgery

155-Rx Croup : use racemic epinephrine before intubating

your pt.

156-Rx Free air under diaphragm : go to OR

157-Rx Abnormal hemostasis due to uremia : DDAVP,

Cryopre, conjugated estro

158-Rx Pancreatic pseudocyst : only drain them if persist

more then 6W or > 5 cm.

159-Rx Capillary hemangioma: mostly regress by age of 7

160-Rx Acute torsade de points: Mg replacement

161-Rx MgSo4 tox: stop MgSo4, give Ca gluconate

162-Rx CAD + EF<40% : think about Ace I

163-Rx Dec frequency of relapses of MS: INF beta

164-Rx Anemia of prematurity : Iron supp, periodic Hgb

checking and blood transfusion if needed

165-Rx Spinal injuries: think about cortico

166-Rx Ascities in cirrhotic pt : diagnostic paracentesis ,

Page 9: USMLE Step 2 Treatment Notes

salt restricted diet ,spironolactone ,

167-Rx Giant cell tumor : refer it to expert!

168-Rx Nocardia : cotri

169-Rx Clavicle Fx : figure of 8

170-Rx “ persistent “ nocturnal enuresis : DDAVP ( not

imipiramine , also know which nocturnal is normal )

171-Rx PCO : think about metformin

172-Rx PH of PF <7.2, PF glucose <60 : chest tube

173-Rx Mediastinal adenopathy on CXR : Med broncho +

biopsy

174-Rx bleeding varices : Band ligation is better than

sclerotherapy

175-Rx SAH: think about Nimodipine for preventing

associated ischemia

176-Rx Tourette’s disorder : Haloperidol , pimozide

177-Rx Preventing PCP in transplant pt : cotri

178-Rx ANY gun shot wound to Ant Abd : LAPARATOMY

179-Rx first line for HTN: diuretics/beta blocker

180-( this one is imp) Rx Primary Parathyro : - pt

symptomatic : Surgery , Pt pregnant : surgery, follow up

is difficult : surgery , serum Ca > 1 mg/dl over upper

limit : surgery

181-Rx Basal cell carcinoma : excision removal with “ 1-2

mm” clear margin ( number is imp)

182-Rx erythema margins ( lyme) Doxy / 28 days or

Amoxi ( in pregnant )

183-Rx Late lyme disease : IV ceftriaxone

184-Rx Irregular atherosclerotic lesion in carotid +

blockage >60% : surgery

185-Rx infant with congenital diaphragmatic hernia :

IMMEDIATE orogastric tube .

186-Rx Reye syn: glucose + FFP and mannitol to dec

Page 10: USMLE Step 2 Treatment Notes

cerebral edema

187-Rx Cat Scratch disease: Azithro/5days

188-Rx pt with variceal bleeding needs 5 or more units of

blood in 24 hours : go for TIPS

189-Rx intermittent claudication :as pharm therapy go for

Ca channel blockers.

Armin 01-06-05

190-RX initial drugs in COPD : antichol

191-Rx Isolated LV diastolic dysfunction : beta blocker

192-Rx Colles FX: closed reduction + casting

193-Rx pul emboli with hemo instability or clot in main

pul A. : pul embolectomy

194-Rx in ARDS : think about PEEP

195-Rx preg pt w asymptomatic bacteriuria : nitrofuran /

7-10days

196-Rx infectious mono w upper airway obstruction or “

autoimmune hemolytic anemia “ or “ thrombocytopenia “

: cortico

197-Rx Fibromyalgia : TCA or Cylobezarpine

198-Rx Benign essential tremor : propranolol

199-Rx Superficial thrombophlebits : Local heat, bed rest,

NSAIDs .

200-Rx Atypical mycobacterium infection : Azithro for

prophylaxis

201-Rx MAC: Clarithro + ethambutol ( imp)

202-Rx child w legg calve perthes below 5 years of age :

NO TREATMENT!!!

203-Rx child w legg calve perthes above 5 years of age:

abduction bracing / surgery

204-Rx IE in IV abusers : Vanco + Genta

205-Rx IE in Non-IV abusers : Nafi + Genta

206-Rx condylomata acuminate: Podophyllin

Page 11: USMLE Step 2 Treatment Notes

207-Rx specific phobia : systemic desensitization

208-Rx Tricho : metro for pt + partner

209-Rx ALL pts w BLUNT trauma to abd BUT w signs of

peritoneal irritation : laparatomy.

210-Rx slowing cognitive decline in Alz : Donepezil /

Tacrine

211-Rx Pancreatic Abscess : “ External “ drainage

211-Rx Pancreatic Abscess : “ External “ drainage

212-Rx Granulum Inguinale : Tetra/10-21 days

213-Rx Pertusis : erythro/14 days

214-Rx Pancoast syn: radiation followed by surgery

215-Rx Acute otitis http: Amoxy /10 days , failed Amoxi-

Clav

216-Rx Measles : don’t forget Vit A

217-Rx chest tube drainage of blood more than 1500cc at

first or more than 600cc in 6 hours : surgical thoracotomy

218-Rx RV infarction : immediate volume expansion ,

failed …Dobutamine

219-Rx Vomiting due to chemotherapy: Ondansetron

220-Rx Adjustment disorder: psychodynamic

psychotherapy or brief cognitive psychotherapy

221-Rx Legionella pnumo: high dose erythro or azithro

222-Rx CLL ( w associated symp) : chlorambucil/pred

223-Rx first degree heart block: no Rx!

224-Rx Non displaced scaphoid Fx : cast immobilization

of wrist

225-Rx Displaced scaphoid Fx : Internal fixation

226-Rx premature atrial beats: No RX!

227-Rx Hairy cell leukemia : Cladribine

228-Rx Non-Hodgkin’s lymphoma: CHOP

229-Rx SVC obstruction: Angioplasty w stenting ( imp)

230-Rx Mediastinitis : Thoracotomy for debrid,drain +

Page 12: USMLE Step 2 Treatment Notes

antibiotic therapy

231-Rx displaced femoral neck in “ elderly” : primary

arthroplasty

232-Rx clavicle Fx in infant : no Rx, avoid putting

pressure on arm

233-Rx PID in hospitalized pt : cefoxitin/doxy ,

cefotetan/doxy, clinda/genta

234-Rx PID in non hos pt: cefoxitin/probencid,

cetraixone/doxy ofloxacin(14d)+Metrogyl(14d Both BID)

kaplan

235-Rx Androgen insensivity syn: Gonadectomy ( inc risk

of test cancer)

236-Rx compartment syn due to eschar of burn wounds:

escharotomy

237-Rx Papilloma of breast : Galactogram guided

resection

238-Rx shaft of femur Fx: closed intermedullary fixation

w/o interrupting skin.

239-Rx scoliosis < 20 degree: observe

240-Rx scoliosis >30: Bracing.

241-Rx Scoliosis >40: surgery

242-Rx Shaft of humerus: closed reduction + hanging

cast.

243-Rx dirty looking wound in pt w less then 3 doses of

tet tox: toxoid +Tig ( only situation which u give pt Tig)

244-Rx uncomplicated Basilar skull fx : head elevation ,

fluid restriction.

245-Rx Ludwig Angina: IV peni w coverage for anaerobes

246-Rx Meconium plug syn: Water soluble contrast

enema mm

247-Rx Ovarian torsion: surgery

248-Rx Tubo-ovarian abscess: surgery

Page 13: USMLE Step 2 Treatment Notes

249-Rx volvulus or malrotation: immediate surgery

250-Rx Transposition of great vessels: keep ductus

arteriosus open, go for surgery.

251-Rx whipples & tropical sprue DOXY/CTM/CEFTRIAXONE

252 Rx Sq cell Ca Anus in HIV,Homos : Nigrochemoradiation

Protocol,then Surgery