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The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology Division, Department of Internal Medicine Brawijaya University – Saiful Anwar Hospital, Malang PIN PB PAPDI Workshop on Basic Musculoskeletal Ultrasound Surabaya 5-10-2019

US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

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Page 1: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

The role of ultrasound

in diagnosis and treatment of rheumatic

diseases Focus on knee

dr.B.P.Putra Suryana SpPD-KR, FINASIM

Rheumatology Division, Department of Internal Medicine

Brawijaya University – Saiful Anwar Hospital, Malang

PIN PB PAPDIWorkshop on Basic Musculoskeletal Ultrasound

Surabaya 5-10-2019

Page 2: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Workshop Objective

1. To understand the role of US in

diagnosing rheumatism on knee

2. To understand the role of US in knee

injection

3. To practice performing standard view US

on normal knee

Page 3: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

OUTLINE

• Technical issues

• Normal knee

• US findings in rheumatic diseases: Osteoarthritis

Gout

Pseudogout

Rheumatoid arthritis

Tendinosis

• Guidance for joint injection

Page 4: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Klinik Reumatik dan Osteoporosis Paviliun RS Saiful Anwar Malang

Page 5: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Bimbingan tindakan injeksi intra-artiuler

PPDS IPD FKUB – RSSA Malang

Page 6: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Equipment

Page 7: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Transducers

Linear 12-5 Mhz Curvilinear 9-4 Mhz Compact linear 15-7

Mhz

Jacobson JA. Fundamentals of Musculoskeletal Ultrasound (2nd ed). Elsevier Saunders, 2013.

Page 8: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Transducer positioning

Jacobson JA. Fundamentals of Musculoskeletal Ultrasound (2nd ed). Elsevier Saunders, 2013.

Page 9: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Transducer movements

Heel-toe maneuver Toggle maneuver

Jacobson JA. Fundamentals of Musculoskeletal Ultrasound (2nd ed). Elsevier Saunders, 2013.

Page 10: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Normal knee

Page 11: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Anterior (sagittal view)

Jacobson JA. Fundamentals of Musculoskeletal Ultrasound (2nd ed). Elsevier Saunders, 2013.

Page 12: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Anterior (transversal view)

Jacobson JA. Fundamentals of Musculoskeletal Ultrasound (2nd ed). Elsevier Saunders, 2013.

Page 13: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Anterior (pre-patellar)

Jacobson JA. Fundamentals of Musculoskeletal Ultrasound (2nd ed). Elsevier Saunders, 2013.

Page 14: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Anterior (flexion)

Jacobson JA. Fundamentals of Musculoskeletal Ultrasound (2nd ed). Elsevier Saunders, 2013.

Page 15: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Medial (coronal view)

Jacobson JA. Fundamentals of Musculoskeletal Ultrasound (2nd ed). Elsevier Saunders, 2013.

Page 16: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Lateral (coronal view)

Jacobson JA. Fundamentals of Musculoskeletal Ultrasound (2nd ed). Elsevier Saunders, 2013.

Page 17: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Posterior (transverse view)

Jacobson JA. Fundamentals of Musculoskeletal Ultrasound (2nd ed). Elsevier Saunders, 2013.

Page 18: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

US findings in rheumatism

Page 19: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Knee effusions

Suprapatellar bulging with positive patellar tap test on knee commonly

represent knee joint effusions

Page 20: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Knee joint effusion

Jacobson JA. Fundamentals of Musculoskeletal Ultrasound (2nd ed). Elsevier Saunders, 2013.

Page 21: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Knee joint swelling in OA patients

Slide collection from Rheumatology Division,

Saiful Anwar Hospital, Malang.

Page 22: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Slide collection from Rheumatology Divison, Saiful Anwar Hospital, Malang.

Page 23: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Intra-articular hemorrhage

Jacobson JA. Fundamentals of Musculoskeletal Ultrasound (2nd ed). Elsevier Saunders, 2013.

Page 24: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Osteophytes in knee OA

Osteophyte (spur formation) is a bony-enlargement commonly at joint

margin. It’s a typical findings in OA patients

Page 25: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Osteophytes

Jain M, Samuels J. Musculoskeletal Ultrasound in the Diagnosis of Rheumatic Disease. Bulletin of the NYU

Hospital for Joint Diseases 2010;68(3):183-90.

Page 26: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Joint cartilage damages

Cartilage damages are early pathologic process in OA

Page 27: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Joint cartilage disruption

Jain M, Samuels J. Musculoskeletal Ultrasound in the Diagnosis of Rheumatic Disease. Bulletin of the NYU

Hospital for Joint Diseases 2010;68(3):183-90.

Page 28: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Acute monoarthritis

Acute arthritis on knee may caused by gouty attack, possibility of septic

arthritis must be excluded.

Page 29: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Gout: double contour sign

Jacobson JA. Fundamentals of Musculoskeletal Ultrasound (2nd ed). Elsevier Saunders, 2013.

Page 30: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Diagnostic Test Value of Ultrasonography

Compared to Joint Effusion Crystal Analysis as Gold

Standard for Diagnosing Gouty Arthritis Dini Rahmawati1, Indrastuti Normahayu1, B.P.Putra Suryana2, Harun Al Rasyid3

1Radiological Departement dr. Saiful Anwar General Hospital, Malang 2Internal Medicine Division dr. Saiful Anwar General Hospital, Malang 3Laboratory of Public

Health Medical Faculty of Brawijaya University, Malang E-mail : [email protected]

Slide collection from Rheumatology Division, Saiful Anwar Hospital, Malang.

Page 31: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

2015 GOUT Classification

Criteria (ACR/EULAR)

Page 32: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Tophus in gout

Tophus is formed by uric acid crystals deposition around the joints surrounded by

inflammation area. Sometimes should be distinguished with other nodules.

Slide collection from Rheumatology Division,

Saiful Anwar Hospital, Malang.

Page 33: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Tophus: Hallo sign

Jacobson JA. Fundamentals of Musculoskeletal Ultrasound (2nd ed). Elsevier Saunders, 2013.

Page 34: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Pseudogout: chondrocalcinosis

Pseudo-gout is caused by calcium pyrophospate dihydrate (CPPD)

deposition within the joints causing inflammation and joint cartilage

calcification (chondrocalcinosis)

Page 35: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Pseudogout: chondrocalcinosis

Jacobson JA. Fundamentals of Musculoskeletal Ultrasound (2nd ed). Elsevier Saunders, 2013.

Page 36: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Baker cyst

Posterior swelling at knee joint in OA patients commonly caused by Baker

cyst.

Page 37: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Baker cyst: comma sign

Jacobson JA. Fundamentals of Musculoskeletal Ultrasound (2nd ed). Elsevier Saunders, 2013.

Page 38: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Leg swelling

Ruptured Baker cyst

DVT on calf

Leg swelling caused by ruptured Baker cyst clinically should be

distinguished with deep vein thrombosis on calf.

Page 39: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Ruptured Baker cyst

Jacobson JA. Fundamentals of Musculoskeletal Ultrasound (2nd ed). Elsevier Saunders, 2013.

Page 40: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Pre-patellar bursitis with effusion

Slide collection from Rheumatology Division, Saiful Anwar Hospital, Malang.

Page 41: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Prepatellar bursa

Jacobson JA. Fundamentals of Musculoskeletal Ultrasound (2nd ed). Elsevier Saunders, 2013.

Page 42: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Patellar tendon tendinosis

Jacobson JA. Fundamentals of Musculoskeletal Ultrasound (2nd ed). Elsevier Saunders, 2013.

Page 43: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Quadriceps tendinosis

Jacobson JA. Fundamentals of Musculoskeletal Ultrasound (2nd ed). Elsevier Saunders, 2013.

Page 44: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Joint erosions in RA

Joint erosions in RA patients are best identified on carpal bones, MCP and

PIP joints. Erosions in RA typically starts on joint margins.

Page 45: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Joint erosions on wrist

Jacobson JA. Fundamentals of Musculoskeletal Ultrasound (2nd ed). Elsevier Saunders, 2013.

Page 46: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Pannus in RA

Pannus are proliferative synovium with cells

accumulation and high vascularisation within

the joint lead to develop joint erosions.

Page 47: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Synovial hypertrophy

Jacobson JA. Fundamentals of Musculoskeletal Ultrasound (2nd ed). Elsevier Saunders, 2013.

Page 48: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

US guidance for joint injection

Page 49: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

In-plane and out-of-plane

Page 50: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Standoff positioning

Page 51: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

US guided injection

Spinner DA et al (Eds). Atlas of ultrasound guided musculoskeletal injection. Springer,2014.

Lateral approach knee injection

Page 52: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Accuracy of knee injections

Spinner DA et al (Eds). Atlas of ultrasound guided musculoskeletal injection. Springer,2014.

6. Cunnington J, Marshall N, Hide G, et al. A randomized, doubleblind, controlled study of ultrasound-guided corticosteroid injection into the

joint of patients with infl ammatory arthritis. Arthritis Rheum. 2010;62(7):1862–9.

7. Bum Park Y, Ah Choi W, Kim YK, et al. Accuracy of blind versus ultrasound-guided suprapatellar bursal injection. J Clin Ultrasound.

2012;40(1):20–5.

8. Balint PV, Kane D, Hunter J, et al. Ultrasound guided versus conventional joint and soft tissue fl uid aspiration in rheumatology practice: a

pilot study. J Rheumatol. 2002;29(10):2209–13.

Page 53: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Pes anserine bursa injection

Transducer position with gel standoff over pes anserine bursa with in-

plane needle approach

Spinner DA et al (Eds). Atlas of ultrasound guided musculoskeletal injection. Springer,2014.

Page 54: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Baker’s cyst injection

Probe position over posterior knee with in-plane injection technique

Spinner DA et al (Eds). Atlas of ultrasound guided musculoskeletal injection. Springer,2014.

Page 55: US in diagnosis of rheumatic diseases BP Putra... · The role of ultrasound in diagnosis and treatment of rheumatic diseases Focus on knee dr.B.P.Putra Suryana SpPD-KR, FINASIM Rheumatology

Take Home Message

Musculoskeletal ultrasound is a practical

procedure and useful in identifying joint

abnormalities to support diagnosis

confirmation and intervention in rheumatic

diseases.

Terima kasih dan semoga

bermanfaat