Urine Volume Regulation

Volume Regulation

1. Antidiuretic hormone (ADH)

– IF blood volume LOW– Pituitary releases ADH

Volume Regulation

- ADH causes Water reabsorption

• DCT and Collecting tubules

Volume Regulation

2. Aldosterone– IF blood volume LOW

– Adrenal cortex releases Aldosterone

Volume Regulation

- Aldosterone causes absorption of Sodium

• DCT and Collecting tubules• Results in Water absorption from Collecting tubules

Volume Regulation

3. Amount of solutes in Renal tubule

– The more solutes in urine, the more Water in urine

Renal Disease

1. Renal Obstruction

o Urine “backup” causing inflammation of the Pelvis and Calyces

Renal Obstruction

o Renal Calculi (kidney stones)

- Mineral crystallization- Most common - Calcium

Renal Obstruction

o May obstruct the uretero Treatment

- Pass it- Break it - Lithotripsy- Surgery

2. Proteinuria

o Proteins in the urineo Damaged Bowman’s

capsule

3. Glycosuria

o Glucose in the urineo Excess cannot be

reabsorbed

4. Hematuria

o Blood in the urineo Indicator of kidney

disease

5. Ketonuria

o Ketones in the urine

o Indicates diabetes or starvation (fat metabolism)

6. Casts

o Molds of cells formed in renal tubules

o Indicator of nephron disease

RBC Cast

WBC Cast