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Upper Rate Behavior
for internal use only
Why do we have Upper Rate Responses?
Reduce incidence of tracking inappropriate rhythm and/or rate
for internal use only
Upper Rate Response Initiating Factors
Exercise
Sinus Tachycardia
Atrial Arrhythmia
Sensing of Myopotentials
VA conduction exceeding PVARP
for internal use only
Upper Rate Response Limit
Fastest Atrial rate at which consecutively paced ventricular complexes maintain 1:1 synchrony
• Also known as:• Ventricular Maximum Rate (VMR)• Maximum Tracking Rate (MTR)
for internal use only
Max Track Rate / Max Sensor Rate
Definitions
• The Max Track Rate, or Maximum Tracking Rate, is the fastest rate that intrinsic P-waves can be tracked, or followed by paced Ventricular events with a 1:1 ratio.
• The Max Sensor Rate, is the fastest rate the atria and the Ventricles can be paced, based upon sensor input.
for internal use only
DDD Timing
URI
AVI PVAVI PVARP
VRPBL
PVAB
Atrial Channel
Ventricular Channel
for internal use only
Max Track Rate
• The fastest rate the Ventricular channel can pace when tracking intrinsic P-waves.
for internal use only
Max Track Rate
Programmed settings should be based on
• Patient activity levels
• Age (220 – age)
• LV function
• Chest pain
• Tolerance by the Patient if a PMT occurs
for internal use only
Max Track Rate
Questions to consider
• Can the programmed Max Track Rate be tolerated by the patient for prolonged periods?
• During sinus tachycardia, can a sudden drop in the pacing rate be tolerated?
for internal use only
Upper Rate Behaviors
Fixed-Ratio block/Multiblock (2:1, 3:1, etc)
Wenckebach behavior (Pseudo, Electronic)
Auto Mode Switch (not in this presentation)
for internal use only
Upper Rate Behaviors
Depends on programmed values:
• Max Tracking Rate
• Sensed AV Delay
• PVARP
Upper Rate Behavior
Fixed Ratio Block
for internal use only
AV PVARP
TARP (Total Atrial Refractory Period)
Fixed-Ratio Block (Multiblock)
Fast Upper Rate Response
Simplest way to control upper rate
• TARP = MTR
for internal use only
Fixed-Ratio Block
2:1 Block (one v-paced event per two p-waves)
MTR = 115bpm AVD = 160ms PVARP = 360 ms
for internal use only
PV PVARP
TARP = 440 ms
160 ms + 280 ms
(2:1 block point)
Fixed-Ratio Block
Calculation
• 60,000 / TARP: e.g. 60,000 / 440 ms = 136 BPM
for internal use only
Fixed-Ratio Block
PV interval always remains constant
May be inappropriate in young or physically active patients due to sudden rate drops
Patient tracks P-waves until the atrial rate gets to the 2:1 block
• The Ventricular rate will suddenly go to half the Atrial rate
for internal use only
Fixed-Ratio Block
Fall Down Rate
for internal use only
Atrial
rate
160
140
120
100
14012010080
Stimulatedventricular rate
Sensed Atrial Rate
Ex.: Shipped SettingsPV Delay 150 msPVARP 275 ms2:1-blockpoint 142 min-1
80
60
160
2:1 blocking
Upper Rate Responses
Wenckebach
Upper Rate Behavior
Wenckebach block
for internal use only
Do you remember?
AV Block 2nd degree Mobitz I
for internal use only
Wenckebach
Max Track (MTR) must be programmed slower than the TARP interval
2:1 fixed-ratio block will occur when the P-P intervals become faster than TARP
for internal use only
V-A Interval
Base Rate Interval
MTR
PVARP
PV
W-Period
P
P
P
TARP
Wenckebach
P
Ap Vp Ap Vp Vp
AVAV
for internal use only
Wenckebach behaviour
Look at the VV and AV intervals
for internal use only
Wenckebach
Provides a smoother transition from 1:1 to 2:1 block
Avoids a sudden reduction of the ventricular pacing rate and maintains some degree of AV synchrony
for internal use only
Ventricular Rate (paced)
LowerRate
1:1
Wenckebach Plateau
2:1
3:1
. . . ...
.
Atrial Rate (sensed)
MTR TARP ARRP
Wenckebach
Wenckebach response to increasing Atrial rates
for internal use only
Wenckebach
Example• DDD
• MTR 100 bpm (600 ms)
• AV delay 150 ms
• PVARP 250 ms
• TARP 150 + 250 = 400 ms \150ppm
• Therefore, atrial rates >100 bpm (600 ms) but < 150 bpm will result in Wenckebach behavior
• Max PV delay prolongation is 200 ms (600-400)• PV intervals will vary from 150 - 350 ms
for internal use only
Wenckebach
Calculation to determine if a Wenckebach is present:
• Programmed MTR minus TARP
• In our example: 600 ms - 400 ms = 200 ms
• We have a 200 ms Wenckebach window
for internal use only
60 PPM 130 PPM 143 PPM
Base Rate 60 PPMMTR 130 PPMAV delay 170 MSPVARP 250 MS
TARP = PV Delay + PVARP= 170 + 250= 420 ms 143 PPM (2:1 Block Point)
Atrial Rate Continuum
Base Rate (MTR) TARP
DeviceResponse
1:1 Tracking Wenckebach 2:1 Block
for internal use only
Wenckebach
V-A Interval
Base Rate Interval
MTR
PVARP
PV
W-Period
P
P
P
TARP
P
Ap Vp Ap Vp Vp
AVAV 150 ms
200 ms
600 ms
for internal use only
Maximum Tracking Rate Interval
A-A
PVARP
VRP
MTRI
AV Delay
Pseudo Wenckebach - Upper Rate Behaviour
for internal use only
Wenckebach
Base Rate 60 ppmMTR 120 ppmAV 200 msPV 150 msMin. PV 88 msPVARP 250 ms
for internal use only
Wenckebach
AV PVARP
MTR MTR MTR MTR MTR MTR MTR MTR MTR MTR MTR MTR
AV AV AVPVARP PVARP PVARP PVARP PVARP PVARP PVARP PVARP PVARP PVARP PVARP PVARP
P-wave in alert and sensed
Ventricular pacing at Max Tracking Rate
Base Rate 60 ppmMTR 120 ppmAV 200 msPV 150 msMin. PV 88 msPVARP 250 ms
for internal use only
Wenckebach
Identification
• Variable PV delays
• Sustained high rate pacing
• Occasional change in the beat to beat ventricular rate
• Long PV intervals may initiate an endless-loop Tachycardia
for internal use only
Atrial
rate
160
140
120
100
14012010080
Stimulatedventricular rate
Sensed Atrial Rate
80
60
160
Wenckebach and MTR
= Max. Tracking Rate
TARP
for internal use only
WenckebachFixed-ratioBlock
AMS
AV Delay progressively lengthens
Pauses in pacing operation may be seen
PV Delay constant
AV Delayconstant
until DDI(R)pacing
occurs atthe AMS base rate
Upper Rate Responses
for internal use only
Atrial
rate
160
140
120
100
14012010080
Stimulatedventricular rate
Sensed Atrial Rate
Ex.: Shipped SettingsPV Delay 150 msPVARP 275 ms2:1-blockpoint 142 min-1
80
60
160
2:1 blocking
for internal use only
P V
Factors Limiting Upper Rate
PVARPPV Delay
Programmed PV DelayRate Resp. AV/PV DelayShortest AV/PV Delay
Programmed PVARPRate Resp. PVARP/VRPShortest PVARP/VRP
for internal use only
To mimic normal heart function
SpontaneousPR intervalreduction
70 min-1 130 min-1110 min-1
Tracking with RRAVDenabled
Rate Responsive AV Delay
for internal use only
Rate Responsive AV/PV Delays and Shortest AV/PV Delay
0
50
100
150
90
95
10
0
11
0
10
5
11
5
12
0
12
5
13
0
13
5
14
0
14
5
15
0
15
5
16
0
16
5
17
0
17
5
18
0
18
5
19
0
19
5
Low, 1 ms min-1
Medium, 2 ms min-1
High, 3 ms min-1
200
for internal use only
Rate Responsive AV/PV Delays… … and Shortest AV/PV Delay
0
50
100
150
90
95
10
0
11
0
10
5
11
5
12
0
12
5
13
0
13
5
14
0
14
5
15
0
15
5
16
0
16
5
17
0
17
5
18
0
18
5
19
0
19
5
Low, 1 ms min-1
Medium, 2 ms min-1
High, 3 ms min-1
200
for internal use only
Atrial
rate
160
140
120
100
14012010080
Stimulatedventricular rate
Sensed Atrial Rate
80
60
160
2:1 blocking and RRAVD
Ex.: Shipped SettingsPV Delay 150 msPVARP 275 msWith RRAVD(Low, Medium and High)
for internal use only
PVARP
VRP
Rate Responsive Refractory Periods
Low, 1 ms min-1
Medium, 2 ms min-1
High, 3 ms min-1
for internal use only
PVARP
VRP
Rate Responsive Refractory Periods
Low, 1 ms min-1
Medium, 2 ms min-1
High, 3 ms min-1
for internal use only
PVARP
VRP
Rate Responsive Refractory Periods
Low, 1 ms min-1
Medium, 2 ms min-1
High, 3 ms min-1
for internal use only
PVARP
VRP
Rate Responsive Refractory Periods
Low, 1 ms min-1
Medium, 2 ms min-1
High, 3 ms min-1
for internal use only
MTR Intervall MTR Intervall MTR Intervall MTR Intervall
Pseudo Wenckebach Upper Rate Behaviour
for internal use only
Atrial
rate
160
140
120
100
14012010080
Stimulatedventricular rate
Sensed Atrial Rate
Programmed MTR, too high. Will not limit the rate fall at 2:1 block rate.
80
60
160
2:1 blocking and MTR
= Max. Tracking Rate
for internal use only
Atrial
rate
160
140
120
100
14012010080
Stimulatedventricular rate
Sensed Atrial Rate
Use of a well tailoredsensor will relieve the problems of a high MTR
80
60
160
2:1 blocking
= Max. Tracking Rate
= Max. Sensor Rate
= Sensor Indicated Rate
for internal use only
Summary
One to One tracking is the best upper rate behavior
When tracking at this rate is inappropriate, the device may be programmed to exhibit:
• Fixed Ratio Block (Multiblock)
• Wenckebach
• RR AV delay – PVARP/VRP
• DDIR
• Auto Mode Switch
for internal use only
Summary
When programming
• AV delay
• PVARP
• Max Tracking Rate
Remember
• WenckebachAVD + PVARP < MTR
• 2/1 block (mentioned on Merlin)AVD + PVARP = MTR
for internal use only
Merlin
Upper Rate Behavior
Questions