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Updated School TB Screening Policy Frank Alvarez, MD, MPH and Pamina Bagchi, MPH Los Angeles County Department of Public Health Tuberculosis Control Program

Updated School TB Screening Policy Frank Alvarez, MD, MPH and Pamina Bagchi, MPH Los Angeles County Department of Public Health Tuberculosis Control Program

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Page 1: Updated School TB Screening Policy Frank Alvarez, MD, MPH and Pamina Bagchi, MPH Los Angeles County Department of Public Health Tuberculosis Control Program

Updated School TB Screening Policy

Frank Alvarez, MD, MPH and Pamina Bagchi, MPH Los Angeles County Department of Public Health

Tuberculosis Control Program

Page 2: Updated School TB Screening Policy Frank Alvarez, MD, MPH and Pamina Bagchi, MPH Los Angeles County Department of Public Health Tuberculosis Control Program

Topics

• Background

• Data

• Myth-Busting

• New Approach

• Questions

Page 3: Updated School TB Screening Policy Frank Alvarez, MD, MPH and Pamina Bagchi, MPH Los Angeles County Department of Public Health Tuberculosis Control Program

Introduction

In 1980, amended California Administrative

Code, Title 22, Division 22, Chapter 9, Sections

41301-41329 to enable the Local Health Officer to

mandate tuberculosis (TB) testing of school children, if

deemed necessary, for that specific jurisdiction.

Page 4: Updated School TB Screening Policy Frank Alvarez, MD, MPH and Pamina Bagchi, MPH Los Angeles County Department of Public Health Tuberculosis Control Program

Introduction (2)

From 1985-2011, the TB Control Program has

required all kindergartners and students who have never

previously attended school in California to provide

written documentation of a TB skin test (or

IGRA) result.

Page 5: Updated School TB Screening Policy Frank Alvarez, MD, MPH and Pamina Bagchi, MPH Los Angeles County Department of Public Health Tuberculosis Control Program

Purpose of Previous Pre-K

TB Testing Requirement• To collect County-wide data to

assess improvement in TB control and better understand the presence of TB infection and disease

• To determine the impact of immigration patterns on local TB incidence

Page 6: Updated School TB Screening Policy Frank Alvarez, MD, MPH and Pamina Bagchi, MPH Los Angeles County Department of Public Health Tuberculosis Control Program

Purpose of Previous Pre-K

TB Testing Requirement (2)

• To identify children who are candidates for treatment of latent TB infection (LTBI)

• To measure annual TB infection rates in the school-aged population

Page 7: Updated School TB Screening Policy Frank Alvarez, MD, MPH and Pamina Bagchi, MPH Los Angeles County Department of Public Health Tuberculosis Control Program

7

TB Skin Test Results Among New School Entrants (K-12) and TB Cases (4-18 year old)

in Los Angeles County 1993-2009

93 94 95 96 97 98 99 00 01 02 03 04 05 06 07 08 090

500

1000

1500

2000

2500

-5%

0%

5%

10%

15%

20%

25%

30%

5347

34

39 26 2120

25 27 2715 28 20 18

13 2617

7256

37

35 47 4038

33 30 3427 20 18 13

15 1110

FB_Cases(4-18 Y.O.) US_Cases(4-18 Y.O.) Total_cases US_TST(+)FB_TST(+)

Number of TB Cases % of TST (+)

Page 8: Updated School TB Screening Policy Frank Alvarez, MD, MPH and Pamina Bagchi, MPH Los Angeles County Department of Public Health Tuberculosis Control Program

Myth 1 About TB•Myth: Being infected with TB (positive skin test or blood test) means you have active TB disease.

•Fact: Infection does not necessarily mean disease.TB Infection TB Disease Does not feel sick Usually feels sick Has no symptoms Has symptoms Cannot spread TB bacteria to others May spread TB bacteria to others Usually has a positive skin test or blood test

Usually has a positive skin test or blood test

Has a normal chest x-ray and a negative sputum smear

May have an abnormal chest x-ray, and/or positive sputum smear, and/or positive culture

Needs treatment for TB Infection to prevent developing active TB disease

Needs treatment for active TB disease

Page 9: Updated School TB Screening Policy Frank Alvarez, MD, MPH and Pamina Bagchi, MPH Los Angeles County Department of Public Health Tuberculosis Control Program

Myth 2 About TB

• Myth: TB testing is the same as TB screening.

• Fact: Testing for TB is not the same as screening. TB Screening TB Testing

Risk assessment (series of questions) performed by clinician

Skin test (TST) or blood test (QFT or T-Spot)

If deemed higher risk, test for TB infection is done

If positive, then chest x-ray is done

Page 10: Updated School TB Screening Policy Frank Alvarez, MD, MPH and Pamina Bagchi, MPH Los Angeles County Department of Public Health Tuberculosis Control Program

Myth 1 About Previous Testing Requirement

• Myth: The Pre-K Testing Requirement was used as a method of finding children with active TB disease.

• Fact: The requirement was designed to determine / monitor TB infection rates, NOT to find and treat active TB disease cases. TB Control utilizes contact investigations to find active TB cases of all ages.

Page 11: Updated School TB Screening Policy Frank Alvarez, MD, MPH and Pamina Bagchi, MPH Los Angeles County Department of Public Health Tuberculosis Control Program

Myth 2 About Previous Testing Requirement

• Myth: The Pre-K Testing Requirement was an effective means of getting TB-infected children treated.

• Fact: Monitoring was not in place to ensure that children who tested positive for TB infection began treatment. Evidence suggests that many who did begin treatment did not complete the full treatment regimen.

Page 12: Updated School TB Screening Policy Frank Alvarez, MD, MPH and Pamina Bagchi, MPH Los Angeles County Department of Public Health Tuberculosis Control Program

Myth 3 About Previous Testing Requirement

• Myth: If the requirement were not in place, there would be a rise in pediatric TB cases in LA County.

• Fact: Jurisdictions that either rescinded their Pre-K Testing Requirement, like Riverside County, or that never had a Pre-K Testing Requirement, like San Diego County, have continued to see a steady decline in pediatric TB cases.

Page 13: Updated School TB Screening Policy Frank Alvarez, MD, MPH and Pamina Bagchi, MPH Los Angeles County Department of Public Health Tuberculosis Control Program

New Requirement

• Rescind the testing requirement for children entering kindergarten or a California school for the first time.

• Incorporate universal TB screening and risk-based testing in existing California State physical examination requirement for children entering first grade.

Page 14: Updated School TB Screening Policy Frank Alvarez, MD, MPH and Pamina Bagchi, MPH Los Angeles County Department of Public Health Tuberculosis Control Program

New Requirement (2)

• Health providers, as part of this routine health assessment, will screen students and test them for TB only if a risk factor is present.

Page 15: Updated School TB Screening Policy Frank Alvarez, MD, MPH and Pamina Bagchi, MPH Los Angeles County Department of Public Health Tuberculosis Control Program

New Requirement (3)Old Policy New Policy

Screening for High Risk

None All Students

TB Testing All StudentsOnly those at high risk

Additional Office Visits Needed?

LikelyNot likely

(same as physical exam)

When?Entering

KindergartenEntering

First grade

5

Page 16: Updated School TB Screening Policy Frank Alvarez, MD, MPH and Pamina Bagchi, MPH Los Angeles County Department of Public Health Tuberculosis Control Program

16

Factors to Assess High Risk for TB

If any of these is “Yes” TST or IGRA

• Birth outside US in high-prevalence region

• Travel to high-incidence country > 1 week

Page 17: Updated School TB Screening Policy Frank Alvarez, MD, MPH and Pamina Bagchi, MPH Los Angeles County Department of Public Health Tuberculosis Control Program

Factors to Assess High Risk for TB (2)

If any of these is “Yes” TST or IGRA

• Contact with confirmed or suspected TB case

• Family member with positive TST

Page 18: Updated School TB Screening Policy Frank Alvarez, MD, MPH and Pamina Bagchi, MPH Los Angeles County Department of Public Health Tuberculosis Control Program

Why the Change?

• To promote evidence-based best practice, as recommended by the CDC, AAP, USPSTF, etc.

• To avoid redundancy and prevent fragmented care

• To prevent false positive children from receiving treatments that may harm their livers

Page 19: Updated School TB Screening Policy Frank Alvarez, MD, MPH and Pamina Bagchi, MPH Los Angeles County Department of Public Health Tuberculosis Control Program

Why the Change? (2)

• To focus on placing children in medical homes

• To focus on more effective interventions (e.g. CI)

• To focus on higher-risk populations (e.g. homeless)

Page 20: Updated School TB Screening Policy Frank Alvarez, MD, MPH and Pamina Bagchi, MPH Los Angeles County Department of Public Health Tuberculosis Control Program

Partners• Los Angeles County Office of Education

(LACOE)• Los Angeles Unified School District

(LAUSD) • American Academy of Pediatrics, Local

Chapter (AAP)• American Academy of Family Practice,

Local Chapter (AAFP)• Los Angeles County Medical

Association (LACMA)• American Lung Association in

California (ALAC)

Page 21: Updated School TB Screening Policy Frank Alvarez, MD, MPH and Pamina Bagchi, MPH Los Angeles County Department of Public Health Tuberculosis Control Program

Partners (2)• Child Health and Disability Prevention

(CHDP)• Maternal, Child and Adolescent

Health (MCAH)• Los Angeles County Department of

Health Services (DHS)• CA Department of Public Health, TB

Control Branch (TBCB) • Long Beach Department of Health,

Human Services (LBHHS) • Long Beach Unified School District

(LBUSD)

Page 22: Updated School TB Screening Policy Frank Alvarez, MD, MPH and Pamina Bagchi, MPH Los Angeles County Department of Public Health Tuberculosis Control Program

For Information on IGRAs• Cellestis, a Qiagen Company

(QuantiFERON Gold In-Tube)

Nancy Hyland

[email protected]

(661)289-2557• Oxford Immunotec

(T-SPOT)

Deneen Jackson

[email protected]

(619)887-6109

Page 23: Updated School TB Screening Policy Frank Alvarez, MD, MPH and Pamina Bagchi, MPH Los Angeles County Department of Public Health Tuberculosis Control Program

TB Control Program Website

Page 24: Updated School TB Screening Policy Frank Alvarez, MD, MPH and Pamina Bagchi, MPH Los Angeles County Department of Public Health Tuberculosis Control Program

TB Control Program Website

Page 25: Updated School TB Screening Policy Frank Alvarez, MD, MPH and Pamina Bagchi, MPH Los Angeles County Department of Public Health Tuberculosis Control Program

Questions?

LA County TB Control Program Website

www.publichealth.lacounty.gov/tb/

Chhandasi Pamina Bagchi, MPHPolicy and Planning, TB Control

[email protected]

(213) 745-0836