Update on “Disease Burden Attributable to Risk Factors in the US” Project

Update on “Disease Burden Attributable to Risk Factors in the US” Project

Armineh Zohrabian, CDCIAWG on Summary and Outcome Measures of Health July 12, 2006

Armineh Zohrabian, CDCIAWG on Summary and Outcome Measures of Health July 12, 2006

Presentation OutlinePresentation Outline

Overview of the specific activities of CDC/Harvard University current Burden of Disease (BOD) project

Brief mention of CDC’s Health Related

Quality of Life Surveillance Program

Overview of the specific activities of CDC/Harvard University current Burden of Disease (BOD) project

Brief mention of CDC’s Health Related

Quality of Life Surveillance Program

BOD ProjectBOD Project

CDC/Harvard University cooperative agreement

$325,000 over 3 years (2004-2007)

CDC/Harvard University cooperative agreement

$325,000 over 3 years (2004-2007)

BOD ObjectivesBOD Objectives

Update 1996 disease burden estimates to the year for which most recent data are available (2001)

Estimate distributions and trends of total and risk-factor attributable disease burden by age, sex, race and geography

Update 1996 disease burden estimates to the year for which most recent data are available (2001)

Estimate distributions and trends of total and risk-factor attributable disease burden by age, sex, race and geography

Specific ActivitiesSpecific Activities

Inputs for estimating disease burden attributable to risk factors are:

Risk factor exposure Uses risk assessment module from the

Comparative Risk Assessment (CRA) Project, WHO

Risk factor hazard Estimates will be based on systematic review

of epi literature Burden of disease

Will use Disability Adjusted Life Years (DALYs)

Inputs for estimating disease burden attributable to risk factors are:

Risk factor exposure Uses risk assessment module from the

Comparative Risk Assessment (CRA) Project, WHO

Risk factor hazard Estimates will be based on systematic review

of epi literature Burden of disease

Will use Disability Adjusted Life Years (DALYs)

Collation of data sources and development of methods to re-distribute ill-defined causes of death in the US

(completed) estimate unbiased overweight and obesity trends from

self-reported data (completed) estimate unbiased trends for other risk factors from self-

reported data (initiated) estimate sub-national risk factor exposure and trends in

risk factor exposure (ongoing)

Development of new algorithms to update 1996 US burden of disease estimates to the year 2000 or 2001(ongoing)

Collation of data sources and development of methods to re-distribute ill-defined causes of death in the US

(completed) estimate unbiased overweight and obesity trends from

self-reported data (completed) estimate unbiased trends for other risk factors from self-

reported data (initiated) estimate sub-national risk factor exposure and trends in

risk factor exposure (ongoing)

Development of new algorithms to update 1996 US burden of disease estimates to the year 2000 or 2001(ongoing)

Specific ActivitiesSpecific Activities(continued)

Contribution to scientific literature

Contribution to scientific literature

Ezzati M, Martin H, Skjold S,Vander Hoorn S, Murray CJ. Trends in National and State-Level Obesity in the USA after correction for self-reported bias. JR Soc Med. 2006 May; 99(5):250-7. Erratum in: J R Soc Med. 2006 Jun;99(6):280.

Christopher J.L. Murray, Sandeep C. Kulkarni and Majid Ezzati. Understanding the Coronary Heart Disease Versus Total Cardiovascular Mortality Paradox: A Method to Enhance the Comparability of Cardiovascular Death Statistics in the United States. Circulation 2006;113;2071-2081

Ezzati M, Martin H, Skjold S,Vander Hoorn S, Murray CJ. Trends in National and State-Level Obesity in the USA after correction for self-reported bias. JR Soc Med. 2006 May; 99(5):250-7. Erratum in: J R Soc Med. 2006 Jun;99(6):280.

Christopher J.L. Murray, Sandeep C. Kulkarni and Majid Ezzati. Understanding the Coronary Heart Disease Versus Total Cardiovascular Mortality Paradox: A Method to Enhance the Comparability of Cardiovascular Death Statistics in the United States. Circulation 2006;113;2071-2081

CDC's Health-Related Quality of Life Surveillance Program CDC's Health-Related Quality of Life Surveillance Program

Housed in the Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion  

Its purpose is to learn about unmet health needs; recognize trends, disparities, and determinants of health in the population

It uses the Healthy Days surveillance measures in summary measures of population health

Housed in the Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion  

Its purpose is to learn about unmet health needs; recognize trends, disparities, and determinants of health in the population

It uses the Healthy Days surveillance measures in summary measures of population health

Resources on Healthy Days MeasuresResources on Healthy Days Measures

  Moriarty DG, Zack MM, Kobau R, Zahran HS. Tracking Health-Related

Quality of Life in the United States 1993-2004. Presented at the Institute of Medicine Committee to Evaluate Measures of Health Benefits for Environmental, Health, and Safety Regulation. Washington, DC, December 1, 2004.  See PowerPoint slides @ http://www.iom.edu/subpage.asp?id=23875

Klementiev A. Chapter 5 -- An Alternative Measure of Years of Healthy Life, from:Estes RJ (Ed). Social Indicators Research Series, 2006; 29 ISBN: 1-4020-5099-2 [In press, available November 15, 2006].    

For additional information, including copies of the measures,  annual state-based HRQOL prevalence data from 1993 and later, and references to research based on the measures, please see the CDC HRQOL Website at http://www.cdc.gov/hrqol .

  Moriarty DG, Zack MM, Kobau R, Zahran HS. Tracking Health-Related

Quality of Life in the United States 1993-2004. Presented at the Institute of Medicine Committee to Evaluate Measures of Health Benefits for Environmental, Health, and Safety Regulation. Washington, DC, December 1, 2004.  See PowerPoint slides @ http://www.iom.edu/subpage.asp?id=23875

Klementiev A. Chapter 5 -- An Alternative Measure of Years of Healthy Life, from:Estes RJ (Ed). Social Indicators Research Series, 2006; 29 ISBN: 1-4020-5099-2 [In press, available November 15, 2006].    

For additional information, including copies of the measures,  annual state-based HRQOL prevalence data from 1993 and later, and references to research based on the measures, please see the CDC HRQOL Website at http://www.cdc.gov/hrqol .