Upload
archie
View
63
Download
0
Tags:
Embed Size (px)
DESCRIPTION
UNITAID’s Strategic Approach to HIV Diagnostics. . XIX International AIDS Conference Brenda Waning. Washington DC 22 July, 2012. Agenda. UNITAID Market Approach to Public Health UNITAID Landscape Reports UNITAID HIV Diagnostics: Recent Investments & New Opportunities. 1. 2. 3. 1. - PowerPoint PPT Presentation
Citation preview
Page 1
UNITAID’s Strategic Approach to HIV
Diagnostics
Washington DC22 July, 2012
XIX International AIDS Conference
Brenda Waning
Page 2
Agenda
UNITAID Market Approach to Public Health
UNITAID Landscape Reports
UNITAID HIV Diagnostics: Recent Investments & New Opportunities
2
3
1
Page 3Slide 3 www.unitaid.eu
UNITAID Market Approach toPublic Health
1
31 2
Page 4
Why UNITAID works through markets
Healthy markets, healthy people
UNITAID aims to promote “healthy”, dynamic market conditions whereby manufacturers have incentives to invest and innovate, while at the same time supply quality public health products at affordable prices and in acceptable formulations that enable the maximum number of people to access them.
www.unitaid.eu
31 2
Page 5
How UNITAID intervenes UNITAID’s role depends upon the particular circumstances in a given market:
• Market catalyst: identify and facilitate adoption and uptake of new and/or superior public health products;
• Market creator: provide incentives for manufacturers to produce otherwise unattractive, low-demand products that yield little profit but have substantial public health benefit to those in need; and
• Market “fixer”: address severe market inefficiencies (e.g. grossly inaccurate demand forecasts and excessive transaction costs) that contribute to low access to quality-assured public health products.
31 2
Page 6Slide 6
UNITAID Market Impact Framework
Market Shortcomings:Price; Availability; Quality; Acceptability; Delivery
www.unitaid.eu
Pathway from market to public health impactCase for intervention
Public health problem & commodity
access issues
Market shortcomings
and their reasons
Innovative market
intervention
Sustainable market impact
Public health impact
Reasons for Market Shortcomings: Absence of market; Lack of external grant funds when commercial incentives are insufficient; Unbalanced market structure (e.g.,monopsony / oligopsony);Structural & capacity issues along the supply chain;Information asymmetries;Barriers to entry & exit.
31 2
Page 7Slide 7
UNITAID is one of several market playersCoordination is critical: Global Fund, PEPFAR, USAID, PDPs, BMGF, WHO, UNAIDS, national governments, etc.
Demand(Buyers
and consumers)
Demand(Buyers
and consumers)
Non-UNITAID Interventions
UNITAIDInterventions
Market Shortcomings
Market Dynamics
Market Shortcomings
Supply(Sellers) Supply
(Sellers)
Policy, regulation, economics, guidelines, innovation, politics
www.unitaid.eu
31 2
Page 8
UNITAID Landscape Analyses2
21 3
Page 9Slide 9
UNITAID Landscape Analyses
1. Disease: public health problem and access issues, global goals, future directions & guidelines for diagnosis & treatment
2. Technology: comparison (pros and cons) of products currently on the market and products in the pipeline;
3. Market: overview of market dynamic trends (past & future), market shortcomings and their reasons, global positioning of key stakeholders
Systematic, forward-looking to proactively and strategically address tomorrow’s challenges and opportunities...today
Identify issues & market opportunities in each niche
21 3
Page 10
UNITAID HIV Diagnostic Landscapes Jun 2011 Annual Oct 2011 Update Jun 2012 Annual
UNITAIDT E C H N I C A L
R E P OR T
HIV/AIDSDiagnostic Landscape
Maurine M. Murtagh2nd Edition – July 2011
www.unitaid.eu/
2011 HIV/AIDS DIAGNOSTIC TECHNOLOGYLANDSCAPE
SEMI-ANNUAL UPDATE
OCTOBER 2011
Page 11
Utilization & Dissemination of Landscapes• Results inform UNITAID’s own strategy & investment
decisions
• UNITAID Annual HIV Market Forum: bring together the world's leading experts (prevention, diagnosis, treatment) to identify & prioritize market-based opportunities for all organizations
• Close linkage to WHO Treatment 2.0 through WHO HIV Diagnostics Working Group & Global Fund through Market Dynamics Advisory Group
• Commitment to transparency & Public Goods (data, information, methods, tools, results, lessons learned)
21 3
Page 12
UNITAID HIV Diagnostics: Recent Investments & New Opportunities
3
21 3
Page 13
UNITAID HIV Diagnostic Activities & Investments
Discovery Development Evaluation Registration Market
21 3
CHAI/UNICEF (Mar 2012):Catalyze Market; Scale-up
MSF (Mar 2012):Operational Research
Landscape Analyses
Market Intelligence Systems: monitoring, estimate impact
Market Entry (Dec 2012):Address Developers’ Market Barriers
Collaboration with and others
New InvestmentArea
Page 14
• Unprecedented innovation in HIV POC diagnostics, but several market entry barriers exist
• Market entry definition: "completion of the marketing approval steps required to commercialize a product"
• Most significant market entry barriers:• Unclear, absent, and/or inconsistent regulatory
pathways to market, register, and use new diagnostics – each country has own requirements
• Slow global quality assurance processes• Private funding (venture capital) hard to access
New Area: Market Entry Barriers HIV POC Diagnostics
Discovery Development Evaluation Registration Market
21 3
Page 15Page 15
Implications of market entry barriers for new POC HIV Diagnostics • Delay in market entry of new products• Additional costs and resources needed to enter market
may increase final price & limit extent of uptake• Limited competition. First-to-market may capture
market share and block market entry of better, less expensive products in the pipeline
• Long term disincentives for continued innovation
UNITAID will consider new investments to developers & leverage existing projects (CHAI/UNICEF, MSF) to address market entry barriers
www.unitaid.eu
Summary & Conclusions• After a decade of suboptimal access to diagnostics, new innovative POC products offer real promise to bring diagnostics to underserved populations & increase quality of HIV care
• UNITAID’s comprehensive, strategic approach to HIV diagnostics:
• Landscape reports & market intelligence (public goods) • Investments in projects to scale-up access POC diagnostics• Investments to address POC market entry barriers• Collaboration with stakeholders. Global Fund: coordinated approach, supplier meetings, etc. and WHO/UNAIDS Treatment 2.0: umbrella to share information, results, lessons learned for future guidance