Undifferenciated sarcoma

2012-05983 MH

• Female 67 years old

• Weight loss 15 kg

• Self palpation a mass of proximal thight

2012-05983 MH

2012-05983 MH MRI April 2012

Per cutaneous biopsy•Undifferenciated sarcoma•Grade 3

Chest CT: Normal

2012-05983 MH

Ki-67

2012-05983 MH

67 years oldMRI April 2012

What do you propose?

• Front line surgery?

• Radiotherapy?

• Chemotherapy?

2012-05983 MH

What do you propose?

• Front line surgery?

• Radiotherapy?

• Chemotherapy?

A 60 mg/m2 J1

I: 3g/m2 J1 J267 years oldMRI April 2012

June 2012: post 2 cycles CT: + 3 cm2012-05983 MH

What do you propose?

• Surgery?

• Radiotherapy?

• 2nd line chemotherapy?

October 2012: Post RT 50 Gy: - 2 cm2012-05983 MH

Surgery oct 2012

• 15 X 7 cm• Femoral nerve is included• Vessels partially included• 8% residual tumour cells• R0 1 mm

• Pathology

2012-05983 MH

June 2014: MRIChest CT: normal+ 2 years

2012-05983 MH