Understanding

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The 2The 2ndnd generation of generation of Fractional Tx. Fractional Tx.

With CIS-F1 With CIS-F1

The 2The 2ndnd generation of generation of Fractional Tx. Fractional Tx.

With CIS-F1 With CIS-F1

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2

What is What is LASER LASER ??

R : of Radiation

E : Emission

S : by Stimulated

A : Amplification

L : Light

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Diagram of a laserDiagram of a laser

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Diagram of a laserDiagram of a laser

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What makes laser different from other What makes laser different from other light Sources?light Sources?

■ Monochromaticity

■ Coherence : the waves are in phase in time and space.

■ Collimation

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For effective use of For effective use of laser, laser,

practitioners practitioners must understand must understand

‘‘Laser tissue Laser tissue interaction interaction ’’

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Laser and Tissue Interaction:Laser and Tissue Interaction:Laser targets chromophoreLaser targets chromophore

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Laser and Tissue Interaction:Laser and Tissue Interaction:Laser targets chromophoreLaser targets chromophore

Typical chromophores (chromophores’ absorbing laser in

tissue):

- Water (Chromophore of CIS-F1)

- Hemoglobin and Oxy-hemoglobin

- Melanin (including Hair)

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Laser and Tissue InteractionLaser and Tissue Interaction

Laser interacts with tissue by absorption, scatter and/or transmission.

Grothus Draper Law : Laser application of tissue is based on the absorption.

“No Absorption No Effect”

Absorption

Transmission

Scatter

Reflection : 4-7% on skin surface

Refraction

X V“Laser light must be perpendicular with skin surface to minimize refraction”

Without incident angle

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Laser Tissue Absorption SpectrumLaser Tissue Absorption Spectrum

532 nm (KTP)

585 nm (Pulsed Dye) 2940 nm (Er:YAG)

10,600 nm (CO2)

200 1000 50000.1

1

10

100

1000

20000

Hb

HbO2

1550 nm (Er:Glass)

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3 Skin Layers3 Skin Layerswww.sellaslaser.com

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Laser and Tissue InteractionLaser and Tissue Interaction

Vaporization (>100 ºC)Necrosis &

Coagulation(58-85 ºC)

Protein Denaturation

(> 60 ºC)Photobiomodul

ation (< 40 ºC)

LASER

Ablative Laser (CIS-F1) Ablative Laser (CIS-F1)

Benefit

Injury

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Fractional Fractional irradiation irradiation

Benefit

Fractional Tx. deliversmultiful micro-beams,which hits the surfaceof skin in afractionated mannerand allows for fasthealing by intact surrounding healthyTissues.

Laser and Tissue InteractionLaser and Tissue Interactionwww.sellaslaser.com

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Laser and Tissue InteractionLaser and Tissue Interaction

CytokineGF

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10mJ, Moving mode(50mm tip)

Depth: 230 ㎛ Width: 80 ㎛

** Slides of porcine skin

Skin Tissue Interaction(CIS-F1)Skin Tissue Interaction(CIS-F1)www.sellaslaser.com

250mJ, Stamp mode(50mm tip)

Depth: 1800 ㎛ Width: 150 ㎛

200mJ, Stamp mode(100mm tip)

Depth: 1350 ㎛ Width: 200 ㎛

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Laser Light

Absorbed Target

Non absorbed target

*Temperature in the absorbed target will rise.

Selective PhotothermolysisSelective Photothermolysiswww.sellaslaser.com

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Small Blood Vessels are

Typically <450 us

Melanosome is Typically <10ns to

100 ns

Termal Relaxation Time(TRT)Termal Relaxation Time(TRT)www.sellaslaser.com

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CIS-F1CIS-F1(10600(10600 ㎛ ㎛ fractional)fractional)

CIS-F1CIS-F1(10600(10600 ㎛ ㎛ fractional)fractional)

Sellas-evoSellas-evo(1550(1550 ㎛㎛ fractional)fractional)

Sellas-evoSellas-evo(1550(1550 ㎛㎛ fractional)fractional)

Ablative approach

Excellent in skin resurfacing

More effective on single Tx.

Require less than 3 Tx.

Combination enhancement

Prone to surface of skin Tx.(face lift effect)

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Comparison Comparison

Non-ablative approach

Excellent in skin rejuvenation

Minimal downtime

Require less than 5 Tx.

Combination enhancement

Prone to dermis Tx.(face volume up effect)

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–Structural change in Keratinized outer layer (enhance absorption of topicals)

–Biomodulation < 40˚C(Activity of cytokine )–Stimulation of functional

cells (Cytokine,GF…)

-Termal peeling.-Termal peeling.-How it works.-How it works.www.sellaslaser.com

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▪ SpecificationLaser source RF CO2 Laser

Wavelength 10600nm

Operation mode

Stamping / Moving (Scanning)

Pulse energy Stamp: 1-250mJ (Depth: 0.2~1.5mm)Moving: 1-50mJ

Pattern size Handpiece diameter 30mm tip(microbeam dia. 150 ㎛ )

Interface Touch Screen

Weight 30kg

Dimension 40(W)x55(D)*90(H)cm

CIS-F1 CIS-F1 www.sellaslaser.com

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Tip length(Focal length)

50mm 100mm Surgical tip

Microbeam Size

80 ㎛ 120 ㎛

PowerHigher than 100mm tip

applied

Lower than 50mm tip applied

ApplicationDeep

penetration(Deep scar)

Skin resurfacingIncision, Cutting,Nevus removal

CIS-F1 CIS-F1

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CIS-F1 CIS-F1

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CIS-F1 CIS-F1

User mode - easy to pick up the preset protocol

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Tailoring the spot pattern

▪ Tailoring the treatment zone by drawing on canvas (X-Y scanner).▪ Customized design is allowed for intensive treatment without excessive damage to surrounding tissues.

Tailoring the treatment zoneTailoring the treatment zonewww.sellaslaser.com

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[ 16 standard regular forms]

Regular formsRegular formswww.sellaslaser.com

[ Max. 250mJ per micro dot]

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30% lidocaine gel is applied on face; occlude for 30-40 mins with BioMask30% lidocaine gel is applied on face; occlude for 30-40 mins with BioMask

Cooling and topical anesthesia before “ high energy” proceduresCooling and topical anesthesia before “ high energy” procedures

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Immediate redness after Sellas laserImmediate redness after Sellas laserDr. Gabriel Serrano, SpainDr. Gabriel Serrano, Spain

Terminology of LaserTerminology of Laserwww.sellaslaser.com

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Stamping modeStamping mode

Dr. Gabriel Serrano, SpainDr. Gabriel Serrano, Spain

Terminology of LaserTerminology of Laserwww.sellaslaser.com

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Moving modeMoving mode

Dr. Gabriel Serrano, SpainDr. Gabriel Serrano, Spain

Terminology of LaserTerminology of Laserwww.sellaslaser.com

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• Sunscreen above SPF 50

• Vitamin C

• Retinol at night

• EGF, bFGF, Amino acid, Mineral, Co-enzymes, Necleonic acid

• Copper peptide, Glyco-protein

1. Fast recovery against PIH after laser treatment (Whitening)2. Improving skin tone and firmness (tightening).3. Anti-aging restructuring of skin tissue 4. Post-trauma skin repair

Factors: Moisturizing / Anti-inflammatory / Revitalization / Sunscreen

Post-Care TreatmentPost-Care Treatmentwww.sellaslaser.com

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1. C- Vit serum / Lotion + Factor G Lotion + Moisturizing pack

2. Sun screen

3. Away from excessive heat stimulus such as sauna, hot spa

Post CIS-F1 treatment:Immediate care & First week after treatment

Post-Care TreatmentPost-Care Treatmentwww.sellaslaser.com

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[Medical examination and treatment after 1 week Restart skin care at home Skin Healing or tighten mask as for cosmetic care (propymask, Biomask)

[Post CIS-F1 treatment]: Second week after treatment1. Return to regular skin care: C-Vit Lotion + Factor G lotion (scars) RetiseS / Fillderma System (aging), C-Vit DaeSeS (DMAE) for flaccidity Kojic acid / Alfa lipoic / arbutin (bleaching) JuveSeS Teens / SaliSeS(acne)

[Medical examination and treatment after 2 weeks]: Combine treatments

Start aesthetic treatment with chemical peel, IPL, RF, Microdermabrasion, electroporation for complementary approach (Antiaging, Whitening, Tightening)

[Second visit for CIS-F1 treatment after 4 weeks]

Post-Care TreatmentPost-Care Treatmentwww.sellaslaser.com

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1. Renal failure

2. Herpes simplex

3. Acute infection

4.Post thermal injury4.Post thermal injury

Contraindication for SellasContraindication for Sellaswww.sellaslaser.com

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Only Sellas can represent “True” 2nd generation fractional laser!

•Fast high density delivery

• Able to tailor stamping shape

according to lesional shape

• Thermal peeling

AdvantagesAdvantageswww.sellaslaser.com

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PHOTOS (BEFORE/AFTER)PHOTOS (BEFORE/AFTER) PHOTOS (BEFORE/AFTER)PHOTOS (BEFORE/AFTER)

Terminology of LaserTerminology of Laserwww.sellaslaser.com

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Patient age: 28 (Skin type: IV)

After 3 Tx

Skin Photo GallerySkin Photo Gallerywww.sellaslaser.com

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Patient age: 27 (Skin type: IV)

After 3 Tx

Skin Photo GallerySkin Photo Gallerywww.sellaslaser.com

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Patient age: 27 (Skin type: IV)

After 3 Tx

Skin Photo GallerySkin Photo Gallerywww.sellaslaser.com

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Patient age: 29 (Skin type: IV)

After 5 Tx

Skin Photo GallerySkin Photo Gallerywww.sellaslaser.com

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Patient age: 32 (Skin type: IV)

After 3 Tx

Skin Photo GallerySkin Photo Gallerywww.sellaslaser.com

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Patient age: 32 (Skin type: IV)

After 3 Tx

Skin Photo GallerySkin Photo Gallerywww.sellaslaser.com

Patient age: 46 (Skin type: IV)

After 3 Tx

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Patient age: 25 (Skin type: IV)

After 3 Tx

Skin Photo GallerySkin Photo Gallerywww.sellaslaser.com

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Thank you.

The 2The 2ndnd Generation of Fractional Generation of Fractional Ablative Tx. With CIS-F1Ablative Tx. With CIS-F1

The 2The 2ndnd Generation of Fractional Generation of Fractional Ablative Tx. With CIS-F1Ablative Tx. With CIS-F1

®®