Understanding Cancer and Related Topics

Understanding Angiogenesis

Developed by:Lewis J. Kleinsmith, Ph.D.Donna Kerrigan, M.S.Jeanne KellyBrian HollenAn illustrated description of angiogenesis and its importance in cancer research.

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What Is Metastasis?

3. Cancer cells reinvade and grow at new location

Blood vessel

1. Cancer cells invade surrounding tissues and vessels

2. Cancer cellsare transported by the circulatorysystem to distant sites

Metastasis Requires Angiogenesis

Angiogenesis

What Is Tumor Angiogenesis?

Blood vessel

Tumor that can grow and spreadSmall localized tumor

Signaling molecule

Angiogenesis

Normal Angiogenesis in Children

Normal Angiogenesis in Adults

Angiogenesis in tissue during wound healing

Angiogenesis in uterine lining