6
A U p b lo im c s H te c c a H 5 H a th r n d C B te K B r a 1 T a p e r v n e Tunne 1 H 4 S 1,4 Electrica Pennsylvani 1 1 hxl2 4 sdatta ABSTRACT Ultra-low power progress in biosi biosignal recordi ow amplitude o mplantable syste component with r such system. In Heterojunction T elescopic operati channel neural characteristics of amplifier exhibits Hz-2.1 kHz, and 5 nW of power HTFET amplifie achieved, which heoretical limit. equirements are noise model of H design. Categories a B.7.1 [Integrate echnologies. B.8 Keywords Biomedical signa ecording, Steep analog design. 1. INTROD Technology adva and ultra-low po progress in biosig efforts towards li ecording interfa various clinical neurological diso epilepsy [4-9]. Fi Permission to make classroom use is gra for profit or commer on the first page. Co must be honored. republish, to post permission and/or a ISLPED'14, August Copyright © 2014 A http://dx.doi.org/10. el FET-B D Huichu Liu uman Datta al Engineering ia State Unive 16802, USA 2[email protected]d a@engr.psu T r circuit design ignal acquisition ing system is a f neural signals em. The front-en respect to overal this paper, we FET (HTFET)-b ional transcondu spike recording HTFETs, our si s a midband gain an input-referred at a 0.5 V sup er, a noise effi h is significantl Design tradeoff investigated, ba HTFET and comp and Subject d Circuits]: Typ 8.0 [Performanc al processing, L subthreshold slo DUCTION ancements in m ower, low-noise gnal acquisition ghtweight, minia aces, the potent domains such orders including ig. 1 illustrates a digital or hard copie anted without fee prov rcial advantage and th opyrights for compone Abstracting with cr on servers or to re fee. Request permissi 11–13, 2014, La Jolla ACM 978-1-4503-297 1145/2627369.26276 Based U Design a g Dept., ersity, PA, du, u.edu T n techniques ha n. The design o challenging task and limited pow nd low-noise am ll power consum e present a new based neural amp uctance amplifier g. Exploiting th imulation shows n of 39 dB, a gai d noise of 6.27 μ pply voltage. Us iciency factor ( ly lower than s related to gain ased on a compre pared with the b Descriptors pe and Design S e and Reliability ow-noise amplif pe, Tunnel FETs micro electromec circuit designs platforms [1-3]. aturized and pow tial application as diagnosis g stroke, Parkin a block diagram es of all or part of th vided that copies are hat copies bear this no ents of this work own redit is permitted. T edistribute to lists, ions from permissions a, CA, USA. 75-0/14/08...$15.00. 31 Ultra-Lo for Bio 2 Mah 5 Alexa 2,5 Swiss F Technology (E S { 2 mah 5 alexandre ave enabled rap of a multi-chann k, considering th wer budget for mplifier is a critic mption and noise w design of III- plifier employing r (OTA) for mul he unique devi s that the propose n bandwidth of μVrms, consumin sing the propose (NEF) of 0.64 the CMOS-bas n, power and noi ehensive electric baseline Si FinFE s Styles – advance y]: General. fier, Neural sign s, Ultra-low pow chanical (MEM have led to rap With the ongoin wer efficient neur fields extend and treatment nson's disease an of a neural sign his work for personal not made or distribut otice and the full citati ned by others than AC To copy otherwise, requires prior speci s@acm.org. ow Pow o-signal hsa Shoara andre Schm Federal Institu EPFL), Lausan Switzerland hsa.shoara e.schmid} @ pid nel he an cal of -V g a lti- ce ed 12 ng ed is ed ise cal ET ed nal wer MS) pid ng ral to of nd nal recordin multich conditio followin activitie charact resoluti electroe Hz), el 0.5~200 1 Hz), 500 μV biosign general stringen tempera power c device a A critic the fron referred a powe 9]. The rejected hertz to (~M) gain of and pow The no reveals referred explore CMOS purpose current amplifi switchin or ted ion CM or ific Figur ac wer, Low l Acquis an mid ute of nne 1015, n, @epfl.ch 3,6 D { ng system [5]. hannel signal ac oning, a data pro ing transmitter es are classified teristics such ion and inva encephalographic lectrocorticograp 0 Hz), local field extracellular ac V, BW: 100 Hz~ nal acquisition sy l, due to the mi nt heat dissipati ature increase to consumption sho area for implanta cal building bloc nt-end low-noise d noise of < 10 μ er dissipation of e large dc offset d and the pass b o several kiloher to prevent the 40 dB with suffi ower-supply rejec oise efficiency fa the design chall d thermal noise ed the design tec . The subthresh e, to ensure a (I DS ) to reduc ier. However, du ing in CMOS, re 1. (a) A block cquisition syste w-Noise sition 3 Xu 6 Vijaykrish 6 Computer Sc Dept., Pennsyl PA, { 3 lixueq, 6 vija It is composed cquisition, an a ocessing unit for unit. Biosigna d into different as amplitude, asiveness of c (EEG) (amplit phic (ECoG) (a d potential (LFP ction potential or ~7 kHz), etc. Th ystems strongly d icrovolt range of ion limit of im o avoid tissue d ould be sufficient ation purpose. ck in a biosigna e amplifier. For μVrms (lower tha < 10 μW/chann ts at the issue-el band should cove rtz, while provid signal attenuatio icient common-m ction ratio (PSR actor (NEF) is a lenge due to the and the power r chniques to redu hold operation h high transcondu ce the input-refe ue to the g m /I DS further reduc k diagram of a em and (b) its po e Ampl ueqing Li hnan Naray cience and En vania State U 16802, USA ay} @cse.p d of an electrod analog front-end reducing the dat als associated w categories, bas bandwidth (B the electrode tude: 10~20 μV, amplitude < 100 ) (amplitude < 5 r neural spikes ( hus, the design o depend on the ap f the neural sign mplantable devic damage) [1, 3], tly low while min l acquisition mic spike acquisitio an the backgroun nel are generally lectrode interfac er a range from ding a high inpu on at the sensor mode rejection ra RR) should also widely accepted e tradeoff betwee reduction. Many uce the NEF [1, has been introdu uctance (g m ) at erred thermal n limit set by the ction of NEF multi-channel b ower breakdow lifier yanan ngineering University, psu.edu de array for d for signal ta rate of the with neural sed on their BW), spatial s [3, 6]: , BW < 100 0 μV, BW: 5 mV, BW < (amplitude < objectives of pplication. In nals and the ces (< 1 ºC the system nimizing the crosystem is on, an input- nd noise) and required [1- ce should be hundreds of ut impedance [1, 3, 6]. A atio (CMRR) be ensured. d metric that en the input- works have 4-10] using uced for this a low bias noise of the e 60 mV/dec and power biosignal wn. [5] 57

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Page 1: Tunnel FET-Based Ultra-Low Power, Low-Noise Ampllifier

AUpbloimcsHteccaH5Hathrnd

CBte

KBra

1Tapervne

Tunne

1H4S

1,4ElectricaPennsylvani

11hxl2

4sdatta

ABSTRACTUltra-low powerprogress in biosibiosignal recordiow amplitude omplantable syste

component with rsuch system. In Heterojunction Telescopic operati

channel neural characteristics of amplifier exhibitsHz-2.1 kHz, and 5 nW of power HTFET amplifieachieved, whichheoretical limit. equirements are

noise model of Hdesign.

Categories aB.7.1 [Integrateechnologies. B.8

Keywords Biomedical signaecording, Steep

analog design.

1. INTRODTechnology advaand ultra-low poprogress in biosigefforts towards liecording interfa

various clinical neurological disoepilepsy [4-9]. Fi

Permission to makeclassroom use is grafor profit or commeron the first page. Comust be honored. republish, to post permission and/or a ISLPED'14, August Copyright © 2014 Ahttp://dx.doi.org/10.

el FET-BD

Huichu Liu uman Dattaal Engineeringia State Unive16802, USA [email protected]@engr.psu

T r circuit designignal acquisitioning system is a f neural signals em. The front-enrespect to overal

this paper, weFET (HTFET)-bional transconduspike recording

f HTFETs, our sis a midband gainan input-referredat a 0.5 V sup

er, a noise effih is significantl

Design tradeoffinvestigated, ba

HTFET and comp

and Subject d Circuits]: Typ

8.0 [Performanc

al processing, Lsubthreshold slo

DUCTION ancements in m

ower, low-noise gnal acquisition ghtweight, miniaaces, the potent

domains such orders includingig. 1 illustrates a

digital or hard copieanted without fee provrcial advantage and thopyrights for compone

Abstracting with cron servers or to refee. Request permissi11–13, 2014, La Jolla

ACM 978-1-4503-2971145/2627369.26276

Based UDesign

a g Dept., ersity, PA,

du, u.edu

T

n techniques han. The design ochallenging taskand limited pow

nd low-noise amll power consume present a newbased neural ampuctance amplifierg. Exploiting thimulation showsn of 39 dB, a gaid noise of 6.27 μpply voltage. Usiciency factor (ly lower than fs related to gainased on a comprepared with the b

Descriptorspe and Design Se and Reliability

ow-noise amplifpe, Tunnel FETs

micro electromeccircuit designs platforms [1-3]. aturized and powtial application

as diagnosis g stroke, Parkina block diagram

es of all or part of thvided that copies are hat copies bear this noents of this work ownredit is permitted. Tedistribute to lists, ions from permissionsa, CA, USA. 75-0/14/08...$15.00. 31

Ultra-Lo for Bio

2Mah5Alexa

2,5Swiss FTechnology (E

S2mah

5alexandre

ave enabled rapof a multi-channk, considering thwer budget for

mplifier is a criticmption and noise w design of III-plifier employingr (OTA) for mulhe unique devis that the proposen bandwidth of μVrms, consuminsing the propose(NEF) of 0.64 the CMOS-bas

n, power and noiehensive electric

baseline Si FinFE

s Styles – advancey]: General.

fier, Neural signs, Ultra-low pow

chanical (MEMhave led to rapWith the ongoin

wer efficient neurfields extend

and treatment nson's disease an

of a neural sign

his work for personal not made or distribut

otice and the full citatined by others than ACTo copy otherwise, requires prior [email protected].

ow Powo-signalhsa Shoaraandre SchmFederal InstituEPFL), LausanSwitzerland hsa.shoara

e.schmid @

pid nel he an cal of -V g a lti-ce ed 12 ng ed is

ed ise cal ET

ed

nal wer

MS) pid ng ral to of nd nal

recordinmultichconditiofollowinactivitiecharactresolutielectroeHz), el0.5~2001 Hz), 500 µVbiosigngeneralstringentemperapower cdevice a

A criticthe fronreferreda powe9]. Therejectedhertz to(~MΩ) gain of and powThe noreveals referredexploreCMOSpurposecurrent amplifiswitchin

or ted ion

CM or

ific

Figurac

wer, Lowl Acquisan mid ute of nne 1015,

n, @epfl.ch

3,6

D

ng system [5].hannel signal aconing, a data proing transmitter es are classifiedteristics such ion and invaencephalographiclectrocorticograp0 Hz), local field extracellular ac

V, BW: 100 Hz~nal acquisition syl, due to the mint heat dissipatiature increase toconsumption shoarea for implanta

cal building blocnt-end low-noised noise of < 10 μer dissipation of e large dc offsetd and the pass bo several kiloher

to prevent the f 40 dB with suffiower-supply rejecoise efficiency fa

the design challd thermal noise ed the design tec. The subthreshe, to ensure a

(IDS) to reducier. However, duing in CMOS,

re 1. (a) A blockcquisition syste

w-Noisesition

3Xu6Vijaykrish

6Computer ScDept., Pennsyl

PA, 3lixueq,6vija

It is composedcquisition, an aocessing unit for

unit. Biosignad into different as amplitude, asiveness of c (EEG) (amplitphic (ECoG) (ad potential (LFPction potential or~7 kHz), etc. Thystems strongly dicrovolt range ofion limit of imo avoid tissue dould be sufficientation purpose.

ck in a biosignae amplifier. For μVrms (lower tha

< 10 μW/channts at the issue-el

band should covertz, while providsignal attenuatio

ficient common-mction ratio (PSR

actor (NEF) is a lenge due to theand the power rchniques to redu

hold operation hhigh transcondu

ce the input-refeue to the gm/IDS

further reduc

k diagram of a em and (b) its po

e Ampl

ueqing Li hnan Naraycience and Envania State U16802, USA ay @cse.p

d of an electrodanalog front-endreducing the dat

als associated wcategories, basbandwidth (Bthe electrode

tude: 10~20 µV,amplitude < 100) (amplitude < 5r neural spikes (hus, the design odepend on the apf the neural sign

mplantable devicdamage) [1, 3], tly low while min

l acquisition micspike acquisitio

an the backgrounnel are generally lectrode interfacer a range fromding a high inpuon at the sensormode rejection raRR) should also

widely acceptede tradeoff betweereduction. Many uce the NEF [1, has been introduuctance (gm) at erred thermal nlimit set by the

ction of NEF

multi-channel bower breakdow

lifier

yanan ngineering University,

psu.edu

de array for d for signal ta rate of the with neural sed on their

BW), spatial s [3, 6]: , BW < 100 0 µV, BW: 5 mV, BW < (amplitude < objectives of pplication. In nals and the ces (< 1 ºC the system nimizing the

crosystem is on, an input-nd noise) and

required [1-ce should be hundreds of

ut impedance [1, 3, 6]. A

atio (CMRR) be ensured.

d metric that en the input-

works have 4-10] using

uced for this a low bias

noise of the e 60 mV/dec

and power

biosignal

wn. [5]

57

Page 2: Tunnel FET-Based Ultra-Low Power, Low-Noise Ampllifier

cn

T(a[saddeAsdmisete

InTrsatrccSwrthdimns

2CCTcit[a

Vo

ltag

eG

ain

consumption of thneural recording s

The steep subthrTFET) has eme

applications, taki11]. Significant

such as prototypeand noise characdevelopment [12designs includinefficient advantaAuthors in [16] fscale the bias cudegraded gain omodels, the powes of great inter

explore the desiechnology barrie

n this paper, weTFET (HTFET) ecording based

simulations to acand noise reductiradeoffs related

comprehensive ncharacteristics of Si FinFETs. The we discuss the ecording systemhe simulation

describes the Hmprovement of

noise. The performshown in Section

2. POWERCMOS-BASCMOS-based neuThe work in [4] capacitive feedbats superior area a10]. Later, the a

and achieved a si

Figure 2. Neuoutpu

Frequency

Vo

ltag

e G

ain

fL=1/(2πRC2)

fH=Gm,O

fz=

(b)

he amplifier is insystems.

reshold slope (Serged as a proming benefit of tprogress has beee device demoncterization, heter2-15]. Recent wng variation anaages over CMOfirst explored thurrent in a SiG

of 27.7 dB. Hower-noise tradeoff rest to investigagn optimization

ers in neural reco

e propose a newneural amplifieon a shared

chieve gain impron beyond the Cd to power-no

noise model in [1f HTFETs for ne

reminder of thefundamental ch

m. Section 3 showsetup with noi

HTFET telescopithe neural amp

mance evaluationn 5, followed by c

R-NOISE CHSED NEURAural amplifiers hproposed a neu

ack network, whiand power efficieuthors in [9] expignificant power

ural amplifier (ut thermal noise

y

AM=C1/C2

OTA/(2πAMCL)

C2/CL

=(fHC1CL)/C22

nherently difficu

SS) Tunnel Fieldminent candidatthe sub-thermal en made for the stration, high-frerogeneous integrwork on TFET alysis further exOS at reduced e steep SS indu

Ge TFET neural wever, due to twas not fully stu

ate the power-nns using TFETs ording systems.

w design of a IIIer for multi-chatelescopic OTA

rovement and simCMOS limit. To oise-performance17], and explore eural amplifier dee paper is as follhallenges in CMws the advantagise modeling dic OTA design plifier including n of the HTFET conclusions.

HALLENGEAL AMPLIFave been well st

ural amplifier topich has been widency at a given inplored the theorereduction with a

(a) schematic ane characteristics

Frequen

fL

Ou

tpu

t N

ois

e

Resistor Noise (2R)

fc(c)

ult in CMOS-base

d Effect Transiste for low-voltaenergy switchinTFET technolog

equency switchinration and procemodeling, circu

xplore its energvoltages [16-18ced high gm/IDS

amplifier with the lack of noiudied. Therefore,noise tradeoff an

to overcome th

-V Heterojunctioannel neural spikA through circumultaneous powanalyze the desige, we apply the unique devi

esign compared ows. In Section

MOS-based neurges of HTFET andetails. Section

for performangain, power an

neural amplifier

ES IN FIERS tudied in literaturpology based ondely adopted due nput-referred noietical limit of NEa modified folde

nd (b) gain, (b) s [1, 4].

ncy

vni,OTA

fH

C2

C1+C2+Cin

OTA Noise)

Neural AmplifieNoise

ed

tor ge ng gy ng ess uit gy 8]. to a

ise , it nd he

on ke uit

wer gn

a ce to 2,

ral nd 4

nce nd r is

re. n a

to ise EF ed-

cascodesharingreduce cascodework inshowin

Fig. 2aemployelementgain, AcapacitiinterfacMOSFEfL=1/(2where Censure t

Due tolow freeffectivthe trahowevepower-nspectrumfrom thBy enspseudo-thermal

where Cof the in

expressapproxi

where gand loadifferensubthrethe theAccordtransistbias cuweak irespectidownsc40 V-1

headrooof the p

where Ivalue o∙ ,

NEF=1amplifiappliedcalculat

A

er

e OTA. Furthermg architecture sui

the NEF, the de topology withn [6] explores ne

ng good operation

a shows the neuys the capacitivents (R) and an OTAM, of the neuraive coupling rejce. The pseudETs with resistan

2πRC2). The highCL is the load cthe half-plane-ze

the frequency requency flicker ve technique for ansistor gate arer, is constrainenoise tradeoff.

um of the neural he OTA and psesuring the corne-resistor thermal noise spectral d

, =Cin is the OTA innput pair. ,

sion for ,imated as [1, 7, 9

, =gm,input and gm,load

ad transistors in tnt OTA topologeshold gate coupermal voltage

ding to Eq. (1) antors to maximizeurrent, the input inversion (high ively. However, caled IDS is requi

gm/IDS limit of om at low-VDD apower-noise trade≡ ,IOTA is the total of the input-refe,⁄ ≪1 is the theoretier with only thd to all CMOSted as 2.02 (assu

more, the authoritable for multi-cdesign in [8] utih source-degeneeural amplifier dn compatibility w

ural amplifier toe feedback netwoTA with a voltageal amplifier is Ajects the dc offsdo-resistor connce over 1012 Ω.h cutoff frequenapacitance. C2≪ero fz higher than

range of neural and thermal n

flicker noise redrea [4-10]. Theed by the powFig. 2c showsamplifier in [4]

eudo-resistor (in er frequency fc≪al noise is mindensity , is( )nput capacitance

is the OTA inp

over a -3d9]

, (d are the transcothe neural amplifgies and has a vpling factor: (kBT/q) and k

nd (2), to minimie gm,input and gm,in

and load transisgm/IDS) and stroto reduce the p

ired, which in tuCMOS. Furthe

also degrades theoff is indicated ( /2⁄bias current of t

erred noise. Assu≪ 1, and substitu≈ (κ ∙⁄tical limit in anhermal noise coS-based circuits

uming IOTA=2IDS

rs in [7] presentchannel recordinglizes a low-nois

eration resistors. designs at a low with digital buildi

opology proposeork (C1, C2), psee gain of Gm,OTA.AM = C1/C2 (Fiset from the elecnsists of diod The low cutoff

ncy is fH=Gm,OTA≪ C1CL must ben the operation ba

signals, the minnoise is criticalduction consists oe thermal noise

wer requirement,s the output th and the noise cblue and red, re≪fH, the contrib

nimized. The ins [1]: )⁄ ∙ ,e and related to tput-referred nois

dB bandwith

,, ) ∙ ∙onductances of thfier, respectivelyvalue larger than= κ⁄ ∙ 10, kB is Boltzmanize , , we m

nput/gm,load. Hencstors are sized tong inversion (l

power dissipationurn reduces gm,inp

ermore, the reduhe gm,input/gm,load.

by the NEF [1, 42 ∙ ∙ 4 ∙the OTA, ,uming (C1+C2+

uting Eq.(1) and (∙ , )

n ideal single-stonsidered, whiles. The minimuand κ=0.7 for th

t a hardware g. To further se telescopic

The recent VDD of 1 V, ing blocks.

ed in [4]. It eudo-resistor The voltage

ig. 2b). The ctrode-tissue de-connected frequency is

A/ (2πAMCL), e satisfied to andwidth.

nimization of l. The most of increasing e reduction, , known as ermal noise contributions espectively). ution of the

nput-referred

(1)

the gate area se. A general

of BW is

(2)

he input pair y. β relates to n 1. κ is the

where Vt is nn constant. must size the e, at a fixed o operate in low gm/IDS), n, a severely put due to the uced voltage The essence

4], ) (3)

is the rms Cin)/C1 ≈ 1,

(2) into (3):

(4)

tage bipolar e NEF>1 is um NEF is he input pair)

58

Page 3: Tunnel FET-Based Ultra-Low Power, Low-Noise Ampllifier

for any CMOS neural amplifier using a differential input pair [9], which can be moderately reduced through reference branch-sharing in multi-channel designs [7]. Thus, the power-noise tradeoff in CMOS neural amplifiers inherently limits the design of large-scale multi-channel biosignal acquisition systems.

3. TFETS FOR NEURAL RECORDING APPLICATIONS 3.1 TFET Technology: Advantages of Power-Noise Tradeoff in Neural Amplifier Designs The fundamental limit of gm/IDS in CMOS originates from the thermal energy slope of kBT, which results in an over 60 mV/dec SS. In TFETs, the interband tunneling induced carrier injection mechanism overcomes the thermal energy limit, leading to a sub-60 mV/dec SS. Thus, an improvement of gm/IDS can be achieved in TFETs with SS reduction (Eq. (5)). = 1 = = 10 log = 10SS = κ (5) In this work, we apply the calibrated GaSb-InAs heterojunction TFET (HTFET) models (Fig. 3a-e) reported in [17], which are based on a double-gate device structure with Lg = 20 nm. The device characteristics of gm/IDS vs. IDS and gm/IDS vs. VGS are shown in Fig. 4, comparing HTFETs and Si FinFETs. The improved gm/IDS at low voltage and low IDS provides following advantages in HTFET-based neural amplifier design:

1) Avoiding Gm,OTA degradation at low bias current (IDS). A high Gm,OTA can ensure a low-noise stable operation of an amplifier. At severely scaled IDS, the high gm/IDS of HTFETs can significantly improve gm,input compared to Si FinFETs. Hence, a desired Gm,OTA

can be maintained without increasing the circuit complexity using HTFETs.

2) Reducing , with high gm,input and gm,input/gm,load ratio at low IDS. The steep SS leads to a reduced bias voltage difference to obtain a high gm,input/gm,load ratio. For example, one order magnitude change of gm/IDS is achieved within a 0.2 V window (Fig. 4a), which reduces the overdrive voltage and hence is suitable for low VDD

operation.

3) Enabling VDD scaling to reduce the power consumption (VDD∙IOTA) benefitted from the low-VDD operation of HTFETs.

4) Reducing the NEF by suppressing the thermal energy slope. A steep SS in TFET results in κ>1. Substituting (5) into (4), the minimum NEF of a TFET neural amplifier (NEFTFET,min) is lower than the CMOS limit (NEFCMOS,min): ≈ ∙ ∙ , = = (6)

, = , ∙ , , (7)

where SSTFET,input pair and SSCMOS,input pair stand for the SS of the input pair of the TFET OTA and Si FinFET OTA, respectively.

3.2 HTFET Noise Modeling and Circuit Simulation Setup To design the HTFET neural amplifier, we apply the calibrated Verilog-A device models incorporated with the electrical noise model [17] for HTFETs, and compare the results with the baseline Si FinFET design. The electrical noise model is derived from experimentally validated analytical models, which includes thermal, shot noise and low frequency flicker noise. (The random telegraph noise (RTN) is omitted due to the large transistor gate area in our design.) The modeled noise characteristics comparing HTFETs and Si FinFETs are shown in Fig. 5, where HTFETs exhibit a competitive input-referred noise in the kHz and MHz range compared to Si FinFETs at an operation voltage of 0.3 V. The circuit simulation is performed using Cadence Spectre [19].

Figure 4. gm/IDS characteristics comparison of HTFETs (a, b)

and Si FinFETs (c, d). The device models are from [17].

Figure 5. Electrical noise Verilog-A modeling and input- referred noise comparison [17].

10-3 10-2 10-1 100 101 102 1030

50

100

150

200

250

300GaSb InAs HTFET

VDS

=0.1V

VDS

=0.2V

VDS

=0.3V

gm

/ID

S [

V-1]

IDS [A/m]

Lg=20nm

40 V-1 Limit

0.1 0.2 0.3 0.4 0.5 0.6

1

10

100

VDS

=0.1V

VDS

=0.2V

VDS

=0.3V

gm/I

DS [

V-1]

VGS [V]

Lg=20nm

GaSb-InAs HTFET

40 V-1

Steep SS

0.0 0.1 0.2 0.3 0.4 0.5 0.61

10

100

VDS

=0.1V

VDS

=0.2V

VDS

=0.3V

gm/I D

S [

V-1]

VGS [V]

Lg=20 nm

Si FinFET

40 V-1 Limit

Steep SS

10-3 10-2 10-1 100 101 102 1030

10

20

30

40Si FinFET

VDS

=0.1V

VDS

=0.2V

VDS

=0.3V

gm

/ID

S [

V-1]

IDS [A/m]

Lg=20nm

40 V-1 Limit

(a) (b)

(c)

(d)

0.2 V

0.0 0.1 0.2 0.3 0.410‐16

10‐15

10‐14

10‐13

N‐HTFET

Si FinFET

Inp

ut

Re

ferr

ed

No

ise

SV

G [

V2/H

z]

VGS

[V]

10GHz

VDS=0.4V

0.1 0.2 0.3 0.4

2x10‐12

4x10‐12

6x10‐12

8x10‐12

10‐11

N‐HTFET

Si FinFET

Inp

ut

Ref

err

ed

No

ise

SV

G [

V2 /H

z]

VGS

[V]

100kHz

VDS=0.4 V

(b) (c)

HTFET Noise Model

VG

VD(a)

Noiseless

IDS

Figure 3. Schematics and model parameters for (a) N-HTFETs (b) P-HTFETs, and device characteristics of (c-d) Ids-Vgs and

(e) Ids-Vds , comparing with the baseline Si FinFET [17].

0.0 0.2 0.4 0.6-100

0

100

200

300

400

500 Si FinFET HTFET

VGS

=0.1V

VGS

=0.6V

I DS [A

/m

]

VDS

[V]

Lg=20nm

VGS

=0.1V

0.0 0.2 0.4 0.610-3

10-2

10-1

100

101

102

103

30mV/dec

Lg=20nm

Vds

=0.3V

Vds

=0.5V

SS=60mV/decI DS [A

/m

]

VGS [V]

nHTFET

Si FinFET

-0.6 -0.4 -0.2 0.010-3

10-2

10-1

100

101

102

103

SS=55mV/dec

Vds

=-0.3V

Vds

=-0.5V

I DS [A

/m

]

VGS [V]

Lg=20nm

pHTFET

i

(a) Double Gate N-HTFET ModelGate

GaSb P++ Source Doping:4X1019 cm‐3

InAs N+ Drain Doping:2X1017 cm‐3

Source

InAs

Drain

EOT=0.7nm

Tb=7nm

Lg=20nmElectron Band‐to‐Band Tunneling

*Eg, GaSb = 0.804 eV, Eg,InAs = 0.44 eV, ∆Ebeff= 0.04 eV

i

(b) Double Gate P‐ HTFET ModelGate

GaSb P+ Drain Doping:5X1019 cm‐3

InAs N++ Source Doping:5X1018 cm‐3

Source

GaSb

Drain

EOT=0.7nm

Lg=20nm

Tb=7nm

HfO2 HfO2

Hole Band‐to‐Band Tunneling

(c) (d) (e)

59

Page 4: Tunnel FET-Based Ultra-Low Power, Low-Noise Ampllifier

4. HTFET BASED ULTRA-LOW-POWER, LOW-NOISE OTA

4.1 HTFET-Based Telescopic OTA A modified telescopic OTA topology, inspired from [7] is employed by the HTFET-based OTA (Fig. 6), which utilizes a partial OTA sharing architecture for multi-channel recording. A N-HTFET input pair is used due to its steeper SS (Fig. 3c-d) induced larger gm/IDS. Cascoded M3-M6 are used as gain booster without increasing the input-referred noise-level. Table 1 shows the bias conditions of each transistor in the HTFET OTA. The bias current is 10 nA at VDD=0.5 V, providing a 5 nA bias current for M1-M8. As discussed in Section 2, to maximize the gm1,2 of the input differential pair M1,2, a large W/L ratio is used to achieve high gm/IDS. Similar to the reported CMOS designs [4-9], a large gate-area (WxL) is used to reduce the flicker noise contribution. For M7,8, on the other hand, a minimized W/L is applied to bias the device into strong inversion with small gm/IDS, which increases the ratio of gm1,2/gm7,8 and reduces the thermal noise contribution of M7,8. Since the cascoded M3-M6 have a negligible contribution to the total input-referred noise, the choice of the sizing for these transistors is based on gain requirement. The balance of the output resistance and intrinsic gain is carefully considered for M3-M6. As a result, a high gm/IDS of 253 V-1 is obtained for M1,2, while a gm/IDS of 35 V-1 is used for M7,8, resulting g m 1 , 2 / g m 7 , 8 ≈ 7 . 2 .

For performance comparison, we design a Si FinFET OTA as a baseline with a similar topology and bias current (10 nA). A supply voltage of 1 V is required in Si FinFET OTA due to the overdrive voltage requirement of the stacked devices. Similarly, M1,2 operate in subthreshold regime while M7,8 are biased in strong inversion regime, using the sizes presented in Table 2. However, due to the limited gm/IDS and diminished overdrive voltage, gm1,2 and the ratio of gm1,2/gm7,8 (≈3) are significantly decreased at such low-power level, which is detrimental to noise performance. Performance Analysis

Fig. 7a shows the HTFET OTA gain vs frequency for a single channel compared to the baseline Si FinFET OTA. Benefiting from

its high gm/IDS and the cascoding technique, an open-loop gain of 50 dB is achieved in the HTFET OTA at VDD=0.5 V, whereas the Si FinFET OTA shows a degraded gain of 37 dB at VDD=1 V due to extremely limited bias current. The output noise spectrum vs frequency is shown in Fig.7b-c, where the thermal noise dominates the flicker noise which is suppressed owing to the large gate-area of the input pair.

The dominant noise contributor of each transistor and its contribution to the overall input-referred noise is shown in Fig. 8. In the Si FinFET OTA, M7,8 contribute to a significant portion of the overall input-referred noise due to the degradation of gm1,2 and gm1,2/gm7,8. In contrast, an effective suppression of the thermal noise contribution from M7,8 is achieved in the HTFET OTA, given its high gm/IDS. The desired open-loop gain, ultra-low power and competitive noise performance achieved by the HTFET telescopic OTA confirm its advantage for neural amplifier design.

5. THE HTFET NEURAL AMPLIFIER FOR MULTI-CHANNEL BIOSIGNAL RECORDING 5.1 Closed-loop HTFET Neural Amplifier Using the capacitive feedback topology, we implement the closed-loop HTFET neural amplifier based on the proposed telescopic OTA (Fig. 9). To further eliminate the redundant dc bias circuitry, we use the dc output voltage of the OTA (Vout,dc) to bias the common voltage (Vcommon) of the input signal through the resistive

Figure 6. HTFET based telescopic OTA design with sharing architecture for multi-channel recording.

VDD

Vout1

Vin1‐V+Vb1

Gnd

M1 M2

M3 M4

M5 M6

M7 M8

M9

VDD

Ibias

M10

Vb2 Vb2

M8,2

Vout2

Vin2‐

M6,2

M4,2

M2,2

Vb1

M8,m

Voutm

Vinm‐

M6,m

M4,m

M2,m

Vb2

Vb1

m# channel recording

P-HTFET S

D

G IDS

N-HTFET

S

D

G IDS

W/L[µm/µm]

gm/Ids

[V-1]Vds

[mV]Vgs

[mV]M1,2 50/1 253 67 50M3,4 1/50 202 150 73M5,6 1/10 40 -92 -92M7,8 0.2/40 35 -81 -179M9,10 0.2/10 169 109 82

W/L[µm/µm]

gm/Ids

[V-1]Vds

[mV]Vgs

[mV]M1,2 100/2 28.7 220 40M3,4 30/0.2 28.6 79 21

M5,6 8/0.2 28.55 -68.4 -68.4

M7,8 0.1/80 9.8 -423 -492M9,10 2/2 27 209 205

Table 1. Transistor Sizing of the HTFET Telescopic OTA

Table 2. Transistor Sizing of the Si FinFET Telescopic OTA

Figure 7. Voltage gain (a) and output noise vs. frequency (b-c)

of HTFET and Si FinFET OTAs.

Figure 8. Noise contribution of each transistor to the overall

input-referred noise from 10Hz to 1 kHz.

100 101 102 103 104 105 1060

10

20

30

40

50

60

-180

-120

-60

0

Solid: HTFET OTA Dash: Si FinFET OTA

Ph

as

e [d

eg.]

Gain

Ga

in [

dB

]

Frequency [Hz]

Telescopic OTA Design

Phase

100 101 102 103 104 105 10610-12

10-11

10-10

10-9

10-8

10-7

10-6

10-5

Flicker

Noise

M1,2 WxL=40x0.8 m2

M1,2 WxL=80x1.6 m2

M1,2 WxL=100x2 m2

Ou

tpu

t N

ois

e [V

/H

z]

Frequency [Hz]

Si FinFET OTA

Thermal

Noise

(a)

(b)(c)

100 101 102 103 104 105 10610-12

10-11

10-10

10-9

10-8

10-7

10-6

10-5

Thermal

Noise

Flicker

Noise

M1,2 WxL=20x0.4 m2

M1,2 WxL=30x0.6 m2

M1,2 WxL= 50x1 m2

Ou

tpu

t N

ois

e [V

/H

z]

Frequency [Hz]

HTFET OTA

0

20

40

60

80

M1, M2Thermal

Noise

M7, M8Thermal

Noise

M7, M8Shot Noise

M1, M2Shot Noise

M1, M2FlickerNoise

Others

Co

ntr

ibu

tio

n t

o t

he

Tota

l In

pu

t R

efe

rre

d N

ois

e

HTFET OTA Si FinFET OTA

Thermal noise contribution from M7,8 is suppressed in HTFET OTA.

Flicker noise is suppressed by increasing the transistor gate area.

60

Page 5: Tunnel FET-Based Ultra-Low Power, Low-Noise Ampllifier

divider network (Rb) at Vcommon=Vout. In the OTA simulation, the common dc voltage of the input signal, Vin,dc, is set to 1/2Vout,dc. Hence, by setting Rb=R, the input signal can be biased at 1/2Vout,dc. A diode-connected Si FinFET as in [1, 4-10] is used to construct the pseudo-resistor Rb and R for the Si FinFET neural amplifier, where a W/L of 0.2 µm/8 µm is used for Ma1-2 (Fig. 9b). For the HTFET neural amplifier, shorted source-gate connections [16] can be applied by taking advantage of the asymmetrical source/drain characteristic, while an additional conduction path through Ma3-4

(Fig. 9a) is required due to the uni-directional characteristics. A W/L of 0.2 µm/6 µm is applied to Ma1-4 in the HTFET neural amplifier. The values of the capacitors are selected as C2 = 500 fF, and C1/C2

=100 to provide a 40 dB mid-band gain. CL is varied from 500 fF to 2 pF to tune the pass band of the amplifier. For the Si FinFET neural amplifier, C2=500 fF and C1/C2 = 50 are used, due to the degraded open-loop gain.

5.2 Voltage Gain and Noise Performance The gain and output noise vs. frequency characteristics are shown in Fig. 10, comparing HTFET and Si FinFET neural amplifier designs at different load capacitor conditions (fH decreases as CL increases). A midband gain of 39.4 dB is achieved in the HTFET neural amplifier, as compared to 28.1 dB in the Si FinFET neural amplifier. This gain advantage of the HTFET neural amplifier arises from the improved gm originating from the steep SS induced high gm/IDS. The output thermal noise spectrum exhibits similar characteristics as in Fig. 2c, for both Si FinFET and HTFET neural amplifiers. For a frequency range below 10 Hz, the noise contribution from the pseudo-resistor dominates the overall output noise, while the thermal noise of the OTA dominates the frequency range between fL and fH. As discussed in Section 2, the low cutoff frequency fL is determined by R and C2, while C1/C2 is constant. Thus, the bandwidth of the designed neural amplifier can be tuned by varying R (Rb) and C2 to satisfy the operational bandwidth requirement in different application domains.

5.3 Power-Noise Tradeoff The input-referred noise spectrum for HTFET and Si FinFET neural amplifiers are shown in Fig. 11a. At the same Ibias of 10 nA, the HTFET neural amplifier exhibits over 4 times reduction of the input-referred noise within the pass band compared to the Si FinFET neural amplifier. Moreover, reducing the input-referred noise of the Si FinFET neural amplifier can only be achieved by degrading its power performance. When increasing Ibias by 4 times (40 nA) and 16 times (160 nA) while increasing all the transistor widths accordingly (4 times at Ibias= 40 nA, 16 times at Ibias=160 nA), the input-referred noise of the Si FinFET neural amplifier is reduced by 2 times and 4 times, respectively. Such noise reduction is due to the increased gm1,2 of the OTA at a fixed gm/IDS (at a constant NEF). The Si FinFET neural amplifier shows comparable input-referred noise at Ibias=160 nA and VDD=1 V as the HTFET neural amplifier at Ibias=10 nA and VDD=0.5 V. Hence, an approximate 32 times power reduction over the Si FinFET design is

achieved in the HTFET neural amplifier, considering the design target to obtain the same input-referred noise level.

The performance metrics of the HTFET and Si FinFET neural amplifiers at CL= 2 pF and Ibias=10 nA are summarized in Table 3 and compared with other designs [8, 16]. A bandwidth of 12 Hz (fL) to 2.1 kHz (fH) and power consumption of 5 nW are achieved in the HTFET design with an input-referred noise of 6.27 µVrms integrated over 10 Hz to 1 kHz, which is close to the estimated minimum , of 5.26 µVrms achieved by an ideal OTA at CL=2 pF and AM=40 dB [1]. The Si FinFET neural amplifier, however, shows a bandwidth from 4 Hz to 529 Hz at the same Ibias (10 nA), while fH is degraded due to the limited gm. The increased , at nanowatt power levels imposes inevitable drawbacks on practical applications of the Si FinFET amplifier. Both CMRR and PSRR are improved in the HTFET amplifier compared to the Si FinFET design. A competitive linearity performance of the HTFET and Si FinFET amplifiers, indicated by the total harmonic distortion (THD), is also achieved (compared to Si FinFET, the impact of Ids-Vgs non-linearity in HTFET is compensated by the stable operation bias at low-VDD). For a single-channel, the total transistor area of 259.2 µm2 is achieved in HTFET amplifier compared to 452 µm2 in Si FinFET amplifier.

Compared to the reported CMOS designs [4, 6, 8, 9], the HTFET neural amplifier exhibits superior power-noise performance (Fig.

Figure 9. Closed-loop neural amplifier topology and pseudo resistor schematics.

Pseudo Resistor (R and Rb) Schematic

(a) S-G Connected HTFET

(b) Diode Connected Si FinFET

Ma1

Ma1

Ma2

Ma3 Ma4

Ma2

+

-C1

Vout

C1

C2

C2

R

Rb

Rb

R

CLvref

vin-

OTA

Vcommon

Figure 10. Si FinFET(a, c) and HTFET(b, d) neural amplifier

gain vs. frequency and output noise vs. frequency.

Figure 11. (a) Input referred noise spectrum for HTFET and Si FinFET neural amplifiers and (b) Supply current vs.

vin,rms/√bandwidth for NEF benchmarking.

10-1 100 101 102 103 104 105

-20

-10

0

10

20

30

-360

-300

-240

-180

-120

-60

Ph

ase

[d

eg.]

Gain

Gai

n [

dB

]

Frequency [Hz]

Si FinFET Neural Amplifier

28dB

CL=500f, 1p, 2p, 4p

Phase

10-1 100 101 102 103 104 1050

10

20

30

40

50

-360

-300

-240

-180

-120

-60

Gain

Gai

n [

dB

]

Frequency [Hz]

HTFET Neural Amplifier

CL=500f, 1p, 2p, 4p

39 dB

Phase

10-1 100 101 102 103 104 10510-12

10-11

10-10

10-9

10-8

10-7

fH

CL=500fF, 1p, 2p, 4pOu

tpu

t N

ois

e [V

/H

z]

Frequency [Hz]

HTFET Neural Amplifier

Resistor Noise

OTA Thermal Noise

fL

10-1 100 101 102 103 104 10510-15

10-14

10-13

10-12

10-11

10-10

10-9

10-8

10-7

10-6 Si FinFET Neural Amplifier

CL=500f, 1p, 2p, 4p

Ou

tpu

t N

ois

e [V

/H

z]

Frequency [Hz]

fH

Resistor Noise

OTA Thermal Noise

fL

(a) (b)

(c) (d)

10-1 100 101 102 103 10410-8

10-7

10-6

10-5

10-4

10-3

HTFET Neural Amplifier: I

bias=10nA

Ibias

=10nA

Ibias

=40nA

Ibias

=160nA

Inp

ut

Ref

erre

d N

ois

e [

V/

Hz]

Frequency [Hz]

Si FinFET Neural Amplifier:(a) (b)

10-2 10-1 100 10110-4

10-3

10-2

10-1

100

101

102

103

Si FinFET

Neural

Amplifier

[this work]HTFET

Neural

Amplifier

[6]

[8] [9]

NEF=10

Su

pp

ly C

urr

ent

[A

]

vin,rms

/BW [Vrms

/Hz]

NEF=1

[4]

[this work]NEF

CMOS,min

61

Page 6: Tunnel FET-Based Ultra-Low Power, Low-Noise Ampllifier

11b). A NEF of 0.64 (Table 3) is obtained in the HTFET neural amplifier owing to the steep SS, which outperforms the NEF of 5.18 in the baseline Si FinFET design. This low NEF achieved by the HTFET design also outperforms the optimal NEF for both CMOS (NEFmin =2.02) and Bipolar (NEFmin=1) based designs. Moreover, the new HTFET neural amplifier shows significant gain improvement compared to the SiGe TFET design in [16], benefiting from the cascaded transistors and steeper SS of III-V HTFETs. The telescopic OTA topology employed by our design is also known to be more power-noise efficient [7, 8] compared to the symmetrical current-mirror OTA topology in [16]. The comparison of the noise performance cannot be applied here because of the different assumption of the Fano factor for shot noise and neglecting of the thermal and flicker noise in [16].

6. CONCLUTIONS In this paper, we investigate the unique device characteristics of steep slope HTFET for multi-channel biosignal acquisition. By exploring the high gm/IDS characteristics, we propose a new HTFET neural amplifier design using a shared telescopic OTA topology to enable a nanowatt power-level operation, which also provides a voltage gain improvement and noise reduction compared to the Si FinFET-based design. Using a comprehensive noise model, we analyze the power-noise tradeoff in HTFET neural amplifier designs, which highlights advantages of the steep SS and low-VDD operation for mitigating the aggravated thermal noise limit from the power reduction. At a highly downscaled bias current of 10 nA and supply voltage of 0.5 V, our proposed HTFET neural amplifier design exhibits a midband gain of 40 dB, a -3dB bandwidth from 12 Hz to 2.1 kHz, and an approximate 32 times power reduction over the baseline Si FinFET design to achieve the same input-referred noise level. The performance evaluation further reveals the superior power-noise efficiency of the HTFET-based design, including a NEF of 0.64 significant lower than the theoretical NEF limits using CMOS or Bipolar technologies. The remarkable performance

improvement and desired power-noise tradeoff confirm the advantages of HTFET technology to overcome the CMOS technology barrier for multi-channel biosignal acquisition system applications.

7. ACKNOWLEDGMENTS This work is supported in part by the National Science Foundation (NSF) ASSIST ERC 1160483. This work is also supported in part by STARnet, a Semiconductor Research Corporation program sponsored by MARCO and DARPA.

8. REFERENCES [1] Harrison, R.R. 2008. The Design of integrated circuits to

observe brain activity. IEEE Proceedings. [2] Nurmikko et al. 2010. Listening to brain microcircuits for

interfacing with external world—progress in wireless implantable microelectronic neuroengineering devices. IEEE Proceedings.

[3] Bafar, V. M. and Schmid, A, 2013. Wireless Cortical Implantable Systems, Springer New York.

[4] Harrison, R.R. and Charles, C. 2003. A low-power low-noise CMOS amplifier for neural recording applications. IEEE JSSC.

[5] Shoaran et al 2014. Compact Low-power Cortical Recording Architecture for Compressive Multichannel Data Acquisition. IEEE Trans. Biomed. Circuits Syst.

[6] Zhang et al 2012. Design of Ultra-Low Power Biopotential Amplifiers for Biosignal Acquisition Applications. IEEE Trans. on Biomed. Circuits and Syst.

[7] Majidzadeh et al 2011. Energy efficient low-noise neural recording amplifier with enhanced noise efficiency factor. IEEE Trans. on Biomed. Circuits and Syst.

[8] Shoaran et al 2012. Design techniques and analysis of high-resolution neural recording systems targeting epilepsy focus localization. In IEEE EMBC.

[9] Wattanapanitch, W., Fee, M., Sarpeshkar, R. 2007. An Energy-Efficient Micropower Neural Recording Amplifier. IEEE Trans. on Biomed. Circuits and Syst.

[10] Ruiz-Amaya et al 2010. A comparative study of low-noise amplifiers for neural applications. In ICM’10.

[11] Seabaugh, A. C. and Zhang, Q. 2010. Low-voltage tunnel transistors for beyond CMOS logic. IEEE Proceedings.

[12] Zhou et al. 2012. Novel gate-recessed vertical InAs/GaSb TFETs with record high ION of 180μA/μm at VDS = 0.5V. In IEEE IEDM.

[13] Bijesh et al 2012. Flicker noise characterization and analy-tical modeling of homo and hetero-Junction III-V Tunnel FETs. In Device Res. Conf. (DRC).

[14] Bijesh et al. 2013. Demonstration of In0.9Ga0.1As/GaAs0.18

Sb0.82 near broken-gap tunnel FET with ION=740μA/μm, GM= 70μS/μm and gigahertz switching performance at VDS=0.5V. In IEEE IEDM.

[15] Rooyackers et al 2013. A new complementary heterojunction vertical Tunnel-FET integration scheme. In IEEE IEDM.

[16] Trivedi et al 2013. Exploring Tunnel-FET for ultra low power analog applications: A case study on operational transconductance amplifier. In ACM/EDAC/IEEE DAC.

[17] Pandey et al 2014. Electrical noise in heterojunction interband tunnel FETs. IEEE TED.

[18] Avci et al. 2013. Energy efficiency comparison of nanowire heterojunction TFET and Si MOSFET at Lg=13nm, including P-TFET and variation considerations. In IEEE IEDM.

[19] Cadence® Virtuoso Spectre Circuit Simulator, 2009.

Table 3. Performance Comparison with Other Simulation Works

HTFET Amplifier

(this work)

FinFET Amplifier

(this work)

Shoaran 2012 [8]

Trivedi 2013 [16]

Technology 20 nm

HTFET 20 nm Si FinFET

.18 µm CMOS

90 nm SiGe TFET

Bias Current

10 nA 10 nA 2.84 µA ~3 nA

Supply Voltage

0.5 V 1 V 1.8 V 1 V

Power 5 nW 10 nW 5.11 µW 3.6 nW

Closed-loop Gain

39.4 dB 28.1 dB 39.9 dB 27.7 dB

Bandwidth (fL-fH)

12 Hz-2.1 kHz

(CL=2 pF)

4 Hz-529 Hz (CL=2 pF)

30Hz-2.5kHz(tunable)

0.036 Hz-3.2 kHz

(N/A)

Input-Referred

Noise

6.27µVrms (10Hz - 1kHz)

29.7µVrms* (10Hz- 1kHz)

1.30 µVrms (1Hz-

100kHz)

3.1 µVrms**(N/A)

CMRR 56 dB 42 dB 78 dB 64 dB

PSRR 70 dB 58 dB 57 dB 55 dB

THD 0.69%

(2 mVp-p) 0.67%

(2 mVp-p) - -

NEF 0.64 5.2 1.94 - *At Ibias=160 nA, the integrated input-referred noise of the Si FinFET neural amplifier from 10Hz to 1kHz is 6.99 µVrms with corresponding 16x increase of transistor width. ** Tunnel diode shot noise model with a fano factor of 1 were used for [16] with thermal noise neglected.

62