TUFTS UNIVERSITY SCHOOL OF MEDICINE …momi.de/symposium/wp-content/uploads/2018/02/CV... · TUFTS UNIVERSITY SCHOOL OF MEDICINE ... 2/1/83 - 7/31/83 House ... 9 October 1998: General

TUFTS UNIVERSITY SCHOOL OF MEDICINE

CURRICULUM AND BIBLIOGRAPHY

February 5, 2018

Timothy Edward McAlindon M.D. M.P.H. M.R.C.P. Chief, Division of Rheumatology, Tufts Medical Center Professor of Medicine and Natalie V. Zucker and Milton O. Zucker Chair of Rheumatology, Tufts University School of Medicine Director, Center for Internet-Based Epidemiologic Research, Division of Clinical Care Research 4th Floor, 35 Kneeland St., Boston, MA 02111 Phone: 617-636-5645 Email: [email protected]

E D U C A T I O N

Medical School and Graduate School

Year of Degree Degree Institution

1982 Medical Degree - Bachelor in Medicine (BM)

Southampton University Medical School, Southampton, UK

1993 Doctorate in Medicine (DM) Southampton University Medical School, Southampton, UK

1995 Masters in Public Health (MPH) Boston University School of Medicine

P O S T D O C T O R A L T R A I N I N G

Internships 8/1/82 - 1/31/83 House Physician

Royal United Hospital, Bath, BA1 3NG, UK

2/1/83 - 7/31/83 House Surgeon Queen Elizabeth Hospital, Birmingham, B15 2TH, UK

Residencies 8/1/83 - 1/31/84 SHO in ER The Royal Hospital, Cleveland Rd,

Wolverhampton, West Midlands, WV2 1BT, UK

2/1/84 - 12/27/85 Internal Medicine SHO

Torbay Hospital, Torquay, TQ2 7AA, UK

12/28/85 - 1/31/88 Medical Registrar Southmead Hospital, Westbury-on- Trym, Bristol, BS10 5NB UK

Fellowships 2/1/88 - 4/30/90 Arthritis & Rheumatism

Council Research Fellow in Rheumatology

Bristol Royal Infirmary, Bristol, BS2 8HW, UK

5/1/90 - 6/31/95 Senior Registrar in Rheumatology & General

St Thomas' Hospital, London, SE1 7EH, UK

mailto:[email protected]

Page 2 of 24

McAlindon, T.E. of 242

Medicine 9/1/93 – 7/16/95 Arthritis & Rheumatism

Council Visiting Research Fellow

Arthritis Center, A203, Boston University School of Medicine, Boston, MA 02118

L I C E N S U R E A N D C E R T I F I C A T I O N

Date Location State & Certificate Number

1982 General Medical Council, London, UK UK; 2568571

1985 Royal College of Physicians, London, UK

Membership

1993 Joint Committee on Higher Medical Training, London, UK

Accreditation in Internal Medicine & Rheumatology

1994 Commonwealth of Massachusetts Board of Registration in Medicine

MA; 153928

A C A D E M I C A P P O I N T M E N T S

1994 Assistant Professor of Medicine Boston University School of Medicine, MA

1999 Associate Professor of Medicine Boston University School of Medicine, MA

2003 Associate Professor of Medicine Tufts University School of Medicine, MA

2003 Natalie V. Zucker and Milton O. Tufts University School of Medicine, MA Zucker Chair of Rheumatology

2003 Faculty Member Tufts Sackler School of Graduate Biomedical Sciences, MA

2008 Professor of Medicine Tufts University School of Medicine, MA

H O S P I T A L A P P O I N T M E N T S 1994 Attending Physician Arthritis Center, Boston Medical Center, MA

2003 Chief of Rheumatology Tufts-New England Medical Center, MA

2003 Rheumatology Fellowship Training Tufts-New England Medical Center, MA -2010 Program Director

Page 3 of 24


A W A R D S A N D H O N O R S

1988 Arthritis & Rheumatism Council Junior Research Fellowship 1989 Risk Factors For Knee OA. Arthritis & Rheumatism Council Project Grant (held

jointly with C. Cooper MD) 1992 Environmental factors predicting nephritis in SLE - Lupus UK Project Grant 1992 South West Thames Regional Rheumatology (Syntex) prize for presentation of

'Environmental factors predicting nephritis in SLE' 1993 Arthritis & Rheumatism Council Travelling Fellowship 2008 Fellow of the American College of Physicians 2010 2010 ACR REF /Amgen /Wyeth Rheumatology Fellowship Training Award. 2012 Boston Magazine's Top Doctors 2014 Boston Magazine's Top Doctors

H O S P I T A L , M E D I C A L S C H O O L O R U N I V E R S I T Y C O M M I T T E E

A S S I G N M E N T S

2002 Boston University: Web Subcommittee Member

2003 – 2004 Tufts-New England Medical Center, Scientific Review Committee, Chair

2003 Tufts-New England Medical Center, Clinical Research Committee: Member

2006 Boston University School of Medicine Thesis Committee for Jingbo Niu PhD, External Reviewer

May 2007 Boston University School of Medicine Thesis Committee for Martin Englund MD PhD, External Reviewer

2007 Tufts-New England Medical Center Center for Clinical Evidence Synthesis - AHRQ Evidence-based Practice Centers (EPC) Submission: Expert Panel Member

2008 Tufts Medical Center Clinical Research Development Committee.

O T H E R M A J O R C O M M I T T E E A S S I G N M E N T S 1995 NIH Scientific Review Committee Member

1996 American College of Rheumatology Abstract Review Committee Member

1998 NIH Multipurpose Arthritis & Musculoskeletal Disease Center Special Review Committee Member

1998 NIH/NIAMS Special Emphasis Panel Member

1999 Ochsner Special Advisory WorkGroup, Consultant

1999 NIH/NIAMS Ancillary Study Protocol Review, Chair


Page 4 of 24




2002 NIH/NIAMS Special Review Committee Member

2002 Institute of Medicine / The National Academies, Glucosamine Working Group

2002 NIH/NIAMS Osteoarthritis Initiative Steering Committee, Voting Member

2002 Massachusetts Department of Public Health, Lupus Registry Planning Group

2003 2005 American College of Rheumatology, Research and Education Foundation, Grant Review Committee Member

2005 NIH/NIAMS Osteoarthritis Initiative Publication Committee, Chair

2006 NIH/NAME Study Section, ad hoc reviewer


2007 Special Government Agent for the FDA

2009-10 Osteoarthritis and Cartilage – Editorial Board Member

2009 - Board Member: Osteoarthritis Research Society International

2009 American College of Rheumatology Abstract Review Committee Chair; Concurrent Session Chair; Abstract Tour Guide leader

2009-12 NIH/NAME Study Section Member

2009 FDA Arthritis Panel Consultant (Xiaflex)

2010 - Arthritis and Rheumatism – Co-Editor (Osteoarthritis)

2010 NIH/NIAMS Roundtable discussion on enhancing clinical trials in orthopaedics and osteoarthritis

2011-12 ACR Chair Musculoskeletal Appropriateness Committee

2012-13 OARSI Chair OA Treatment Guidelines Development Committee

2013 - ACR RA Clinical Treatment Guidelines, Literature Review Team Leader

Page 5 of 24


T R A I N I N G O F G R A D U A T E S T U D E N T S

2003-4 Beth Anne Biggee MD, Rheumatology Fellow “Metabolic Study Of The Absorption And Effects Of Glucose Tolerance Of Oral Ingestion Of Glucosamine Sulfate”.

2004-5 Tanya Doan MD, Rheumatology Fellow “Levels of Proteins C and S levels in Patients with Systemic Lupus Erythematosus: A Pilot Study”

2004-7 Chenchen Wang MD, Rheumatology Junior Faculty, program in testing tai chi for rheumatological disorders

2002-9: Margaret Formica M.S. (Epidemiology): Doctoral Program in Epidemiology, Boston University School of Public Health

2004-9: Grace Lo MD, Rheumatology Junior Faculty, Mentored Arthritis Foundation Clinician Investigator Award, Studies of Magnetic Resonance Imaging in Osteoarthritis

2005-8: Jun Wang MD PhD, Post-Doctoral Fellow, American College of Rheumatology Career Development Award

2009- Jeff Driban PhD, Post-Doctoral Fellow

2010- Raveendra Bannuru MD, Doctoral Program in Clinical Research

2012 - Ming Zhang PhD, Postdoctoral Fellow, Computation image analysis of MRI scans

T E A C H I N G R E S P O N S I B I L I T I E S

1 Annually 1995 – 2002: Rheumatology Component of Biology of Disease Course for first year medical students, Boston University School of Medicine

a. Seronegative Spondarthropathies

b. Systemic Lupus Erythematosus Clinical Features

c. Small Group Patient Interviews

2 Annually 1995 - 2002: Biology of Disease course for final year dental students, Boston University School of Dental Medicine

a. Rheumatology

3 1995 - 2002: Medical Student Precepting and Bedside Teaching, Boston University School of Medicine

a. Rheumatology Clinic (4/month) b. Rheumatology Consult Service (2 months/year) c. Internal Medicine Attending (1 month/year)

4 1995 - 2002: Medical Resident Precepting and Bedside Teaching, Department of Medicine

a. Rheumatology Clinic (4/month) b. Rheumatology Consult Service (2 months/year) c. Internal Medicine Attending (1 month/year)

Page 6 of 24


5 1995 - 2002: Rheumatology Fellow Precepting and Bedside Teaching, Department of Medicine, Boston University School of Medicine

a. Rheumatology Clinic (4/month) b. Rheumatology Consult Service (2 months/year)

6 1995 - 2002: Ad Hoc Clinical Teaching Responsibilities, Department of Medicine, Boston University School of Medicine

a. Firm Conferences b. Morning Reports c. Seminars with Rheumatology Fellows

7 2- 3 sessions per year 1995 – 2000: Clinical Problem Solving Conferences for 3rd year medical students: Rheumatology Seminar. Boston University School of Medicine

8 Fall 1997: Guest Lecturer – Epidemiologic Methods (EB 712), Boston University School of Public Health

9 October 1998: General Medical Pharmacology for BUSMII MD students; Discussion Session Benefit-Risk Analysis of NSAIDs

10 Annually 1996 - 1999: “Common rheumatology problems seen in the primary care

setting.” Lecture/Teaching Session given as part of the Retraining Course for Primary

Care Physicians, Dept. of Primary Care, Boston University School of Medicine

11 Annually 2003 – Tufts University School of Medicine Musculoskeletal Pathophysiology

Course. Osteoarthritis

12 2003 – ongoing: Rheumatology Fellow Precepting and Bedside Teaching, Department of Medicine, Tufts NEMC

a. Rheumatology Clinic (4/month) b. Rheumatology Consult Service (3 months/year)

13 2003 Internet-based Clinical Trials – For the Clinical Trial Methodology course (David Snydman MD), Masters in Clinical Research Curriculum

14 2003 Genetic Studies Over The Internet – For the Clinical Trial Methodology course (Inga Peters PhD), Masters in Clinical Research Curriculum

15 2013- TuftsJunior Faculty Forum Co-host. Group mentoring for junior faculty.

P R O F E S S I O N A L S O C I E T I E S

See above

Page 7 of 24


O F F I C E A N D C O M M I T T E E A S S I G N M E N T S I N P R O F E S S I O N A L

S O C I E T I E S

2009 Osteoarthritis and Cartilage – Editorial Board Member

2009 Board Member: Osteoarthritis Research Society International

2009- American College of Rheumatology Abstract Review Committee Chair; Concurrent Session Chair; Abstract Tour Guide leader

2009 NIH/NAME Study Section Member

2010 Arthritis and Rheumatism – Co-Editor (Osteoarthritis)

M A J O R I N D E P E N D E N T R E S E A R C H I N T E R E S T S I am involved in translational and epidemiologic research into rheumatic diseases, especially osteoarthritis (OA) and systemic lupus erythematosus (SLE), and in the development of Internet-based research study methodologies. A. Osteoarthritis: My research career began with a community-based study of knee OA that generated a number of influential manuscripts concerning its patterns, relationship to physical function and risk factors. At that time I published the first study to OA using MRI. Pursuit of this line of research led me to Boston University in 1993, where I examined effects of a variety of exposures on OA risk including nutrition status and physical activity. In 2002 my focus changed towards translation of the epidemiologic findings into clinical trials. Subsequently, I was performed clinical trials testing the effects of various potential disease-modifying agents for knee OA (vitamin D, collagen hydrolysate and BMP-7); and, more recently, intra-articular corticosteroids. Involvement in the Osteoarthritis Initiative also led me to investigate the participation of bone in the progression of OA in a large ancillary study. B. SLE: I have performed a number of studies investigating clinical and epidemiologic aspects of SLE.

C. Internet-based research study methodologies I originally obtained funding from NIH/NLM to develop a methodology for online clinical trials by conducting a prototype trial of Glucosamine for knee OA symptoms. This endeavor stimulated a program of activities focused on testing online research approaches, including case-control studies and case-crossover studies. The online trial idea won an award from the Boston University Office of Technology Transfer and was recently granted a patent.

Complete List of Published Work in My Bibliography: http://www.ncbi.nlm.nih.gov/sites/myncbi/timothy.mcalindon.1/bibliography/40325953/public/?sort=date&direction=ascending

D. Research Support

Ongoing Research Support R01AR066378-01A1 (McAlindon) 04/01/2015-09/30/2018 NIH/NIAMS

http://www.ncbi.nlm.nih.gov/sites/myncbi/timothy.mcalindon.1/bibliography/40325953/public/?sort=date&direction=ascending

http://www.ncbi.nlm.nih.gov/sites/myncbi/timothy.mcalindon.1/bibliography/40325953/public/?sort=date&direction=ascending

Page 8 of 24


Constitutional and Metabolic Factors associated with the development of Hand OA The goal of this project is to evaluate and contrast the roles of structural and metabolic characteristics in the development of radiographic, symptomatic and erosive hand osteoarthritis. Role: Principal Investigator U01AR067168-01 (McAlindon) 09/01/2014-08/31/2017 NIH

Rapid quantitative composite MRI measurement of Knee OA structural progression The goal of this project develop and validate a responsive, quantitative, MR-based outcome measure and software tool to assess knee OA severity, incorporating measures of cartilage, bone marrow lesions, and effusion, which can be efficiently applied. Role: Principal Investigator R01 AR060718 (McAlindon) 09/01/2012-08/31/2016 NIH/NIAMS

Periarticular Bone Density as a Biomarker of Early Knee Osteoarthritis The goal of this project is to study the longitudinal role of peri-articular bone in OA in the progression of knee OA and suggest tissue targeted interventions Project Role: Principal Investigator Research Support Agreement (McAlindon) 04/02/2012-04/01/2017 Osteoarthritis Research Society International

Prevention and Treatment of Osteoarthritis through the Promotion and Presentation of

Research, Education, and the Worldwide Dissemination of New Knowledge Project Role: Principal Investigator PCORI (Selker) 02/01/2014-01/31/2017 PCORI

A Method for Patient-Centered Enrollment in Comparative Effectiveness Trials:

Mathematical Equipoise The goal of this project is to develop a mathematical equipoise (ME) method to address important clinical problems for which randomized clinical trials (RCTs) have not been done – especially when ultimately widely incorporated into EHRs – should greatly enhance the number, scope, and impact of patient-centered comparative effectiveness trials. This project will develop an ME method for knee osteoarthritis treatment. Project Role: Co-Investigator

I N D E P E N D E N T R E S E A R C H S U P P O R T - C O M P L E T E D

U01 Image Analysis Grant

R01 OA DXA Grant

R01 AR057802-01A1 (McAlindon) 08/09/10-06/30/15 3.00 calendar

Page 9 of 24


$480,953 NIAMS Effects of Intra-Articular Steroids on Structural Progression of Knee OA: A Randomized Controlled Trial

The goal of this project is to test the potential of intra-articular corticosteroids to exert disease modifying effects in knee osteoarthritis (OA).

R01 AR 054938 (McAlindon) 04/01/07-03/31/12 2.40 calendar NIH/NIAMS $490,373 Role of Bone in OA Progression The goal of this project is to study the longitudinal role of peri-articular bone in OA to increase understanding of the mechanisms of progression, refine predictive models, and suggest tissue targeted interventions.

N01 AR 022262 (Eaton) 07/15/02-07/14/2011 NCE 0.96 calendar NIH/NIAMS (Subcontract w/ Memorial Hospital of RI) $20,174 Clinical Centers for the Osteoarthritis Initiative The goal of the OAI is to identify biomarkers for knee osteoarthritis progression.

R21 AT 003621 (Wang) NCE 04/01/07-05/31/11 0.48 calendar NCCAM/NIH $171,500 Tai Chi for Fibromyalgia The project goal is to conduct a pilot randomized controlled trial of Tai Chi for Fibromyalgia

R01 HS 018574 (Schmid) 09/30/09-07/31/12 0.24 calendar AHRQ $253,302 Modernizing Meta-Analysis to Facilitate Comparative Effectiveness Reviews The goal of this project is to develop statistical methods and software for collectively analyzing multiple treatments across multiple endpoints and apply them to rank treatments based on multiple dimensions of health and well-being.

Vitamin RCT Grants

Trial Title: Estrogen Receptor and Aromatase Gene Polymorphisms in Systemic Lupus Erythematosus (PI Wang)

Funding Agency: American College of Rheumatology (ACR Career Development Award)

Amount: $100,000

Period: 2006 - 2008

Role: Co-Investigator

Grant Title: Metabolic Consequences from Oral Ingestion of Glucosamine Sulfate

Funding Agency: Edith Nourse Rogers Memorial Veterans Hospital

Amount: $15,000

Page 10 of 24


Period: 2003 - 2004

Role: Center P.I.

Grant Title: Reproducibility of Knee Joint Cartilage Volume Measurement at Tufts-New England Medical Center

Funding Agency: NEMCH Research Fund

Amount: $25,000

Period: 2003 - 2004

Role: P.I.

Grant Title: An Online Case-Crossover Study of Risk Factors Triggering Acute Gout Flares

Funding Agency: Arthritis Foundation (P.I. Yuqing Zhang DSc)

Amount: $243,000

Period: 07/01/02 - 06/30/05

Role: Co-P.I.

Grant Title: An Internet-Based Randomized Double-Blind Placebo-Controlled Clinical Trial of Zilex in the Treatment of Labial Herpes Simplex Type 1

Funding Agency: Meditech Pharmaceuticals Inc.

Amount: $59,540

Period: 06/05/2001 - 12/31/2002

Role: P.I.

Grant Title: Can Case-Control Studies of Rare Diseases Be Performed Over the Internet?

Funding Agency: NIAMS, NIH (Funded as Project 2 on the Boston University Multidisciplinary Clinical Research Center Grant P60 AR47785 Overall P.I. D. Felson MD)

Amount: $764,094 (direct costs)

Period: 09/01/2001 – 08/31/2007

Role: Project P.I.

Trial Title: Levels of Proteins C and S levels in Patients with Systemic Lupus Erythematosus: A Pilot Study

Funding Agency: Tufts-NEMC General Clinical Research Center

Amount: funded by the General Clinical Research Center

Period: 2004 - 2006

Role: P.I.

Trial Title: Metabolic Consequences from Oral Ingestion of Glucosamine Sulfate

Funding Agency: Tufts-NEMC General Clinical Research Center

Amount: funded by the General Clinical Research Center

Period: 2005 – 2007

Role: P.I.

Grant Title: Technology Development Award (Online Clinical Trial Project).

Funding Agency: Boston University Community Technology Fund

Amount: $50,000

Period: 2000

Role: P.I.

Page 11 of 24


Grant Title: Feasibility of Internet-Based Trials for Osteoarthritis (RO1 LM06856).

Funding Agency: National Library of Medicine, NIH

Amount: $572,538

Period: 09/30/1999 – 09/29/2002

Role: P.I.

Grant Title: A Study of the Feasibility of Internet-Based Clinical Trials in Osteoarthritis

Funding Agency: Arthritis Foundation

Amount: $268,827

Period: 1999 – 2002 (Grant superceded in 1999 by RO-1 award)

Role: P.I.

Grant Title: An Epidemiologic Study of SLE Among Black Women

Funding Agency: NIAMS, NIH (Funded as Project 2 on the Boston University Multipurpose Arthritis Center Grant, Overall PI D. Felson)

Amount: $498,273 (direct costs)

Period: 1997 – 2001

Role: Project P.I.

Grant Title: A Study of the Potential of Indole-3-Carbinol to Benefit Patients with SLE

Funding Agency: Lupus Foundation of America (Delaware Branch)

Amount: $30,000

Period: 1998 - 2000

Role: P.I.

Grant Title: Travelling Fellowship

Funding Agency: Arthritis and Rheumatism Council (UK)

Amount: Salary support for one year

Period: 1993 -1994

Role: P.I.

Grant Title: Environmental Factors Predicting Nephritis in SLE.

Funding Agency: Lupus UK

Amount: $15,000

Period: 1992

Role: P.I.

Grant Title: Risk Factors for Knee OA.

Funding Agency: Arthritis and Rheumatism Council (UK)

Amount: Project Support

Period: 1989 -1991

Role: Co-Investigator

Page 12 of 24


E D I T O R I A L B O A R D S & A C T I V I T Y Ad Hoc reviewer for Annals of Internal Medicine, JAMA, Arthritis & Rheumatism, Journal of Rheumatology, Annals of Rheumatic Diseases, Osteoarthitis & Cartilage 2009 Editorial Board Member – Osteoarthritis & Cartilage 2009 Member, Board of Directors – Osteoarthritis Research Society 2010 Associate Editor – Arthritis and Rheumatism

B I B L I O G R A P H Y

a ) R e f e r e e d p a p e r s

1 Seegmiller JE, Dixon RM, Kemp GJ, Angus PW, McAlindon TE, Dieppe P, Rajgopalan B, Radda GK. Fructose-Induced Aberration of Metabolism in Familial Gout Identified by 31P Magnetic Resonance Spectroscopy. Proc Natl Acad Sci USA 1990;87:8326-8330.

2 Cushnaghan J, Cooper C, Dieppe P, Kirwan J, McAlindon T, McCrae F. Clinical Assessment of Osteoarthritis of the Knee. Ann Rheum Dis 1990;49:768-770.

3 McAlindon TE, Watt I, McCrae F, Goddard P, Dieppe PA. Magnetic Resonance Imaging in Osteoarthritis of the Knee: Correlation with Radiographic and Scintigraphic Findings. Ann Rheum Dis 1991;50:14-19.

4 Cooper C, Cushnaghan J, Kirwan JR, Dieppe PA, Rogers J, McAlindon TE, McCrae F. Radiographic Assessment of the Knee Joint in Osteoarthritis. Annals Rheum Dis 1992;51:80-82.

5 McAlindon TE, Cooper C, Kirwan JR, Dieppe PA. Knee Pain and Disability in the Community. British Journal of Rheumatology 1992;31:189-192.

6 McAlindon TE, Snow S, Cooper C, Dieppe PA. Radiographic Patterns of Osteoarthritis of the Knee Joint in the Community: the Importance of the Patello-Femoral Joint. Ann Rheum Dis 1992;51:844-9.

7 McAlindon TE, Teal D, Dieppe PA. Insulin-like Growth Factor 1 Levels in Osteoarthritis of the Knee. Ann Rheum Dis 1993;52:229-31.

8 Jones AC, Ledingham J, McAlindon T, et al. Radiographic Assessment of Patellofemoral Osteoarthritis. Ann Rheum Dis 1993;52:655-658.

9 McAlindon TE, Cooper C, Kirwan JR, Dieppe PA. Determinants of Disability in Osteoarthritis of the Knee. Annals of the Rheumatic Diseases 1993;52:258-262.

10 McAlindon TE, Giannotta L, Taub N, D'Cruz D, Hughes G. Environmental Factors Predicting Nephritis in SLE. Ann Rheum Dis 1993;52:720-724.

11 Cooper C, McAlindon TE, Snow S et al. Mechanical and Constitutional Risk Factors for Symptomatic Knee OA: Differences Between Medial Tibiofemoral and Patellofemoral Disease. J Rheumatol 1994;21:307-13.

12 Cooper C, McAlindon TE, Coggon D et al. Occupational Activity and Osteoarthritis of the Knee. Ann Rheum Dis 1994;53:90-93.

13 McAlindon TE, Hannan MT, Felson DT et al. Are Risk Factors for Patellofemoral and Tibiofemoral Knee Osteoarthritis Different? J Rheumatol 1996;23:332-7.

Page 13 of 24


14 McAlindon TE, Jacques P, Zhang Y, Hannan MT, Aliabadi P, Weissman B, Rush D, Levy D, Felson DT. Do Antioxidant Micronutrients Protect Against the Development and Progression of Knee Osteoarthritis? Arthritis Rheum 1996;39:648-656.

15 McAlindon TE, Jacques P, Zhang Y, Hannan MT, Aliabadi P, Weissman B, Rush D, Wilson P, Felson DT. The Relationship Between Vitamin D Status and Knee Osteoarthritis Progression. Annals Intern Med 1996;125:353-9.

16 Chaisson C, McAlindon TE, Felson et al. Lack of Association Between Thyroid Status and Chondrocalcinosis or Osteoarthritis: The Framingham Osteoarthritis Study. J Rheumatol 1996;23:711-5.

17 Lloyd ME, Hart DJ, Nandra D, McAlindon TE, Wheeler M, Doyle DV, Spector TD. Relation Between Insulin-Like Growth Factor-I Concentrations, Osteoarthritis, Bone Density, and Fractures in the General Population: The Chingford Study. Ann Rheum Dis 1996;55:870-4

18 Chaisson C, McAlindon TE. Osteoarthritis Of The Hand: Clinical Features and Management. J Musculoskel Med 1997;14:66-77.

19 Felson DT, McAlindon TE, Anderson JJ, Naimark A, Weissman BW, Aliabadi P, Evans S, Levy D, LaValley MP. Defining Radiographic Osteoarthritis for the Whole Knee. Osteoarthritis & Cartilage 1997;5:241-50.

20 Chaisson CE, Zhang Y, McAlindon TE, Hannan MT, Aliabadi P, Naimark A, Levy D, Felson DT. Radiographic Hand Osteoarthritis: Incidence, Patterns, and Influence of Pre-Existing Disease in a Population-Based Sample. J Rheum 1997;24:1337-43.

21 Kauppila LI, McAlindon T, Evans S, Wilson PWF, Kiel D, Felson DT. Disc Degeneration, Back Pain and Calcification of the Abdominal Aorta. Spine 1997;22:1642-7.

22 Zhang Y, McAlindon TE, Hannan MT, Chaisson CE, Klein R, Wilson PW, Felson DT. Estrogen Replacement Therapy and Worsening of Radiographic Knee Osteoarthritis: The Framingham Study. Arthritis Rheum 1998;41:1867-73.

23 Fraenkel L, Zhang Y, Trippel SB, McAlindon TE, LaValley MP, Assif A, Adams KE, Evans SR, Felson DT. Longitudinal analysis of the relationship between serum insulin-like growth factor-1 and radiographic knee osteoarthritis. Osteoarthritis and Cartilage 1998;6:362-367.

24 Fraenkel L, Roubenoff R, LaValley M, McAlindon T, Chaisson C, Evans S, Harris T, Dinarello CA, Felson DT. The Association of Peripheral Monocyte Derived Interleukin 1beta (IL- 1beta), IL-1 Receptor Antagonist, and Tumor Necrosis Factor-Alpha with Osteoarthritis in the Elderly. J Rheumatol 1998;25:1820-6.

25 Felson DT, Couropmitree NN, Chaisson CE, Hannan MT, Zhang Y, McAlindon TE, LaValley M, Levy D, Myers RH. Evidence for a Mendelian Gene in a Segregation Analysis of Generalized Radiographic Osteoarthritis: The Framingham Study. Arthritis Rheum 1998;41:1064-71.

26 McAlindon TE, Wilson PWF, Aliabadi P, Weissman B, Felson DT. Level of Physical Activity and Risk for Incident Radiographic and Symptomatic Knee Osteoarthritis in an Elderly Sample: The Framingham Study. Amer J Med 1999;106:151-7.

27 Adams JG, McAlindon T, Dimasi M, Carey J, Eustace S. Contribution of Meniscal Extrusion and Cartilage Loss to Joint Space Narrowing in Osteoarthritis. Clin Radiol 1999;54(8):502-6.

28 McAlindon TE, Lavalley M, Gulin J, Felson DT. Glucosamine and Chondroitin Treatment for Osteoarthritis? A Systematic Quality Assessment and Meta-Analysis. JAMA 2000;283:1469-75.

29 Zhang Y, Hannan MT, Chaisson CE, McAlindon TE, Evans SR, Aliabadi P, et al. Bone mineral density and risk of incident and progressive radiographic knee osteoarthritis in women: the Framingham Study. J Rheumatol 2000;27(4):1032-7.

Page 14 of 24


30 Cooper C, Snow S, McAlindon TE, Kellingray S, Stuart B, Coggan D, Dieppe P. Risk Factors for the Incidence and Progression of Radiographic Knee Osteoarthritis. Arthritis & Rheumatism 2000;43:995-1000.

31 Eustace S, Dimasi M, Adams J, Ward R, Caruthers S, McAlindon T. In Vitro and In Vivo Spin Echo Diffusion Imaging Characteristics of Synovial Fluid: Potential Non-Invasive Differentiation of Inflammatory and Degenerative Arthritis. Skeletal Radiol 2000;29(6):320-3.

32 Johnson KL, McAlindon TE, Mulcahy E, Bianchi DW. Micochimerism in a Female Patient with Systemic Lupus Erythematosus. Arthritis Rheum 2001;44:2107-2111.

33 Lavalley MP, McAlindon TE, Chaisson CE, Levy D, Felson DT. The Validity of Different Definitions of Radiographic Worsening for Longitudinal Studies of Knee Osteoarthritis. J Clin Epi 2001:54:30-39.

34 Lavalley MP, McAlindon TE, Evans S, Chaisson CE, Felson DT. Problems in the Development and Validation of Questionnaire-Based Screening Instruments for Ascertaining Cases with Symptomatic Knee Osteoarthritis. Arthritis Rheum 5:1105-1113, 2001.

35 McAlindon TE, Gulin J, Chen T, Klug T, Lahita R, Nuite M. Indole-3-Carbinol In Women With SLE: Effect on Estrogen Metabolism and Disease Activity. Lupus 10:779-783, 2001.

36 Baldwin CT, Cupples LA, Joost O, Demissie S, Chaisson C, McAlindon T, et al. Absence of linkage or association for osteoarthritis with the vitamin D receptor/type II collagen locus: the Framingham Osteoarthritis Study. J Rheumatol 2002;29(1):161-5.

37 Formica MK, Palmer JR, Rosenberg L, McAlindon TE. Smoking, Alcohol Consumption and Risk of Systemic Lupus Erythematosus in the Black Women’s Health Study. J Rheumatology 2003:30:1222-6.

38 McAlindon TE, Formica M, Palmer JR, Lafyatis R, Rosenberg L. Assessment of Strategies for Identifying Diagnosed Cases of SLE Through Self-Report. Lupus 2003;12:1-6.

39 Lo GH, LaValley M, McAlindon T, Felson DT. Intra-articular hyaluronic acid in treatment of knee osteoarthritis: a meta-analysis. JAMA 2003;290:3115-21

40 McAlindon T, Formica M, Kabbara K, LaValley M, Lehmer M. Conducting Clinical Trials Over the Internet: Feasibility Study. B Med J 2003:327 (7413):484-7.

41 Formica M, Kabbara K, Clark R, McAlindon T. Can Clinical Trials Requiring Frequent Participant Contact Be Conducted Over the Internet? Results From an Online Randomized Controlled Trial Evaluating a Topical Ointment for Herpes Labialis. Journal of Medical Internet Research 2004;6(1):e6.http://www.jmir.org/2004/1/e6/

42 McAlindon T, Formica M, LaValley M, Lehmer M, Kabbara K. Effectiveness of Glucosamine for Knee Osteoarthritis Symptoms: Results from an Internet-Based Randomized Double-Blind Controlled Trial. American Journal of Medicine 2004;117:643-649.

43 Karlson EW, Costenbader KH, McAlindon TE, Massarotti EM, Fitzgerald LM, Jajoo R, Husm E, Wright EA, Pankey H, Fraser PA. High Sensitivity, Specificity and Predictive Value of the Connective Tissue Disease Screening Questionnaire Among Urban African-American Women. Lupus 2005;14:832-836.

44 Biggee, B. A., C. M. Blinn, McAlindon T.E., Silbert J.E. Low levels of human serum glucosamine after ingestion of glucosamine sulphate relative to capability for peripheral effectiveness. Ann Rheum Dis 2006;65(2): 222-6.

45 Blinn CM, Biggee BA, McAlindon TE, Nuite M, Silbert JE. Sulphate and osteoarthritis: decrease of serum sulphate levels by an additional 3-h fast and a 3-h glucose tolerance test after an overnight fast. Ann Rheum Dis 2006;65:1223-5

http://www.jmir.org/2004/1/e6/

Page 15 of 24


46 Zhang Y, Woods R, Chaisson CE, Neogi T, Niu J, McAlindon TE, Hunter D. Alcohol consumption as a trigger of recurrent gout attacks. Am J Med 2006;119:800 e13-8

47 Zhang Y, Chaisson CE, McAlindon T, Woods R, Hunter DJ, Niu J, Neogi T, Felson, D. T.The online case-crossover study is a novel approach to study triggers for recurrent disease flares. J Clin Epidemiol 2007;60:50-55

48 Biggee BA, Blinn CM, Nuite M, Silbert JE, McAlindon TE. Effects of oral glucosamine sulphate on serum glucose and insulin during an oral glucose tolerance test of subjects with osteoarthritis. Ann Rheum Dis 2007;66:260-2

49 Karlson EW, Watts J, Signorovitch J, Bonetti M, Wright E, Cooper GS, McAlindon TE, Costenbader KH, Massarotti EM, Fitzgerald LM, Jajoo R, Husni ME, Fossel AH, Pankey H, Ding WZ, Knorr R, Condon S, Fraser PA. Effect of glutathione S-transferase polymorphisms and proximity to hazardous waste sites on time to systemic lupus erythematosus diagnosis: results from the Roxbury lupus project. Arthritis Rheum 2007;56:244-54

50 McAlindon T, Formica M, Schmid C, Fletcher J. Change in barometric pressure, and ambient temperature, influence osteoarthritis pain. Am J Med 2007;120:429-434

51 Vlad SC, LaValley MP, McAlindon TE, Felson DT. Glucosamine for pain on osteoarthritis: why do trial results differ? Arthritis Rheum 2007;56: 2267-2277

52 Vlad SC, Lavalley MP, Felson DT, McAlindon TE. Reply. Arthritis Rheum 2008;58(1):333-4. 53 Biggee BA, Blinn CM, Nuite M, McAlindon TE, Silbert JE. Changes in serum levels of

glucosamine and sulphate after ingestion of glucosamine sulphate with and without simultaneous ingestion of glucose. Ann Rheum Dis 2007;66(10):1403-4.

54 De Pablo P, Dietrich T, McAlindon TE. Association of Periodontal Disease and Tooth Loss with Rheumatoid Arthritis in the US Population. J Rheumatol 2008;35(1):70-76.

55 Lo GH, Niu J, McLennan CE, Kiel DP, McLean RR, Guermazi A, Genant HK, McAlindon

TE, Hunter DJ. Meniscal damage associated with increased local subchondral bone mineral density: a Framingham study. Osteoarthritis Cartilage 2008;16(2):261-7.

56 Emrani PS, Katz JN, Kessler CL, Reichmann WM, Wright EA, McAlindon TE, Losina E. Joint space narrowing and Kellgren-Lawrence progression in knee osteoarthritis: an analytic literature synthesis. Osteoarthritis Cartilage 2008 ;16:873-82

57 McAlindon TE, Wang J, Fletcher J, Formica M. Feasibility and validity were demonstrated of an online case-control study using the prototype of recent-onset systemic lupus erythematosus. J Clin Epidemiol 2008;61:671-8

58 Wang J, Kay AB, Fletcher J, Formica MK, McAlindon TE. Alcohol consumption is not protective for systemic lupus erythematosus. Ann Rheum Dis 2009;68:345-8.

59 Wang C, Pablo P, Chen X, Schmid CH, McAlindon T. Acupuncture for Pain Relief in Patients with Rheumatoid Arthritis: A Systematic Review. Arthritis Care & Research 2008; 28:1183-7

60 Wang J, Kay A, McAlindon T. Is Lipstick Associated with Development of Systemic Lupus Erythematosus (SLE)? Clinical Rheumatology 2008;9:1183-7

61 Wang C, Schmid CH, Hibberd H, Kalish R, Roubenoff R, Rones R, Okparavero A,

McAlindon T. Tai Chi for treating knee osteoarthritis: designing a long-term follow up randomized controlled trial. BMC Musculoskeletal Disorders 2008:9;108 (29 Jul 2008) doi:10.1186/1471-2474-9-108

62 Lo GH, Hunter DJ, Nevitt M, Lynch J, McAlindon TE. Strong association of MRI meniscal derangement and bone marrow lesions in knee osteoarthritis: data from the osteoarthritis initiative. Osteoarthritis Cartilage 2009;17:743-747.

63 Lo GH, McAlindon TE, Niu J, Zhang Y, Beals C, Dabrowski C, Hellio Le Graverand MP, Hunter DJ. Bone marrow lesions and joint effusion are strongly and independently

Page 16 of 24


associated with weight-bearing pain in knee osteoarthritis: data from the Osteoarthritis Initiative. Osteoarthritis & Cartilage 2009;17(12):1562-9

64 Wang C, Schmid CH, Hibberd PL, Kalish R, Roubenoff R, Rones R, McAlindon TE. Tai Chi is effective in treating knee osteoarthritis: A randomized controlled trial. Arthritis Rheum 2009;61(11):1545-53.

65 Bannuru, R. R., Natov, N. S., Obadan, I. E., Price, L. L., Schmid, C. H., McAlindon, T. E. Therapeutic trajectory of hyaluronic acid versus corticosteroids in the treatment of knee osteoarthritis: a systematic review and meta-analysis. Arthritis Rheum 2009;61(12):1704-11

66 Wang J, Nuite N, McAlindon TE. Association of estrogen and Aromatase polymorphisms with systemic lupus erythematosus. LUPUS 2010;19:734-740.

67 Ike, R, Arnold E, Arnold, W, Craig-Muller, J, Kaeley G, McAlindon T, Nazerian L, Reginato, A. Ultrasound in American Rheumatology Practice. Arthritis Care & Research 2010;Sep;62(9):1206-19.

68 Hunter DJ, Pike MC, Jonas BL, Kissin E, Krop J, McAlindon T. Phase 1 safety and tolerability study of BMP-7 in symptomatic knee osteoarthritis BMC Musculoskeletal Disorders 2010, 11:232.

69 Felson DT, Lynch J, Guermazi A, Roemer FW, Niu J, McAlindon T, Nevitt MC. Comparison of BLOKS and WORMS scoring systems part II. Longitudinal assessment of knee MRIs for osteoarthritis and suggested approach based on their performance: data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2010 Nov;18(11):1402-7. Epub 2010 Sep 17.

70 Wang C, Schmid CH, Rones R, Kalish R, Yinh J, Goldenberg DL, Lee Y, McAlindon T. A randomized trial of tai chi for fibromyalgia. N Engl J Med. 2010 Aug 19; 363(8): 743-54.

71 Formica MK, McAlindon TE, Lash TL, Demissie S, Rosenberg L.Validity of self-reported rheumatoid arthritis in a large cohort: results from the Black Women's Health Study. Arthritis Care Res 2010 Feb;62(2):235-41.

72 Jawahar R, Yang S, Eaton CB, McAlindon T, Lapane KL: Gender-specific correlates of complementary and alternative medicine use for knee osteoarthritis. J Womens Health (Larchmt), 21(10):1091-1099.

73 Schneider E, Lo GH, Sloane G, Fanella L, Hunter DJ, Eaton CB, McAlindon, T. E. Magnetic resonance imaging evaluation of weight-bearing subchondral trabecular bone in the knee. Skeletal Radiol 2011;40:95-103.

74 McAlindon TE, Nuite M, Krishnan N, Ruthazer R, Price LL, Burstein D, Griffith J, Flechsenhar K. Change in knee osteoarthritis cartilage detected by delayed gadolinium enhanced magnetic resonance imaging following treatment with collagen hydrolysate: a pilot randomized controlled trial. Osteoarthritis Cartilage 2011 19;4:611-619

75 Bannuru RR, Natov NS, Dasi UR, Schmid CH, McAlindon TE. Therapeutic trajectory following intra-articular hyaluronic acid injection in knee osteoarthritis - meta-analysis. Osteoarthritis Cartilage (2011). Doi 10.1016/j/joca.2010.09.014.

76 Driban JB, Lo GH, Lee JY, Ward RJ, Miller E, Pang J, Price LL, McAlindon TE. Quantitiative bone marrow lesion size in osteoarthritic knees correlates with cartilage damage and predicts longitudinal cartilage loss. BMC Musculoskeletal Disorders (2011). doi:10.1186/1471-2474-12-217.

77 McAlindon T, Kissin E, Nazarian L, Ranganath V, Prakash S, Taylor M, Bannuru RR, Srinivasan S, Gogia M, McMahon MA et al: American College of Rheumatology report on reasonable use of musculoskeletal ultrasonography in rheumatology clinical practice. Arthritis Care Res (Hoboken) 2012, 64(11):1625-1640.

Page 17 of 24


78 Brand, J. A., McAlindon, T. E., Zeng, L. A 3D System for Culturing Human Articular Chondrocytes in Synovial Fluid. J. Vis. Exp. (59), e3587, DOI: 10.3791/3587 (2012).

79 Driban JB, Tassinari A, Lo GH, Price LL, Schneider E, Lynch JA, Eaton CB, McAlindon TE, Group OAII: Bone marrow lesions are associated with altered trabecular morphometry. Osteoarthritis Cartilage 2012, 20(12):1519-1526.

80 Yang S, Jawahar R, McAlindon TE, Eaton CB, Lapane KL: Racial differences in symptom management approaches among persons with radiographic knee osteoarthritis. BMC Complement Altern Med 2012, 12:86.

81 Lo GH, Tassinari AM, Driban JB, Price LL, Schneider E, Majumdar S, McAlindon TE: Cross-sectional DXA and MR measures of tibial periarticular bone associate with radiographic knee osteoarthritis severity. Osteoarthritis Cartilage 2012, 20(7):686-693.

82 Lo GH, Harvey WF, McAlindon TE: Associations of varus thrust and alignment with pain in knee osteoarthritis. Arthritis Rheum 2012, 64(7):2252-2259.

83 Lapane KL, Sands MR, Yang S, McAlindon TE, Eaton CB: Use of complementary and

alternative medicine among patients with radiographic-confirmed knee osteoarthritis.

Osteoarthritis Cartilage 2012, 20(1):22-28.

84 McAlindon T, LaValley M, Schneider E, Nuite M, Lee J, Price L, Lo G, Dawson-Hughes B.

Effect of Vitamin D Supplementation on Progression of Knee Pain and Cartilage Volume

Loss in Patients With Symptomatic Osteoarthritis A Randomized Controlled Trial.

JAMA. 2013;309(2):155-162. doi:10.1001/jama.2012.164487.

85 Pang J, Driban JB, Destenaves G, Miller E, Lo GH, Ward RJ, Price LL, Lynch JA, Eaton

CB, Eckstein F, McAlindon TE. Quantification of bone marrow lesion volume and volume

change using semi-automated segmentation: data from the osteoarthritis initiative. BMC

Musculoskelet Disord 2013, 14(1):3.

86 Lee JY, Luc S, Greenblatt DJ, Kalish RA, McAlindon TE. Factors associated with serum

hydroxychloroquine level in lupus patients: renal function could be important Lupus

0961203313476361, first published on February 8, 2013 as

doi:10.1177/0961203313476361

87 Lee JY, Harvey WF, Price LL, Paulus JK, Dawson-Hughes B, McAlindon TE. Relationship

of bone mineral density to progression of knee osteoarthritis. Arthritis Rheum. 2013 Mar 12.

Doi: 10.1002/art.37926

88 Yang S, Dube CE, Eaton CB, McAlindon TE, Lapane KL. Longitudinal use of

complementary and alternative medicine among older adults with radiographic knee

osteoarthritis. Clinical therapeutics. 2013;35(11):1690-702. doi:

10.1016/j.clinthera.2013.09.022. PubMed PMID: 24145044; PubMed Central PMCID:

PMC3880574

89 van Middelkoop M, Dziedzic KS, Doherty M, Zhang W, Bijlsma JW, McAlindon TE,

Lohmander SL, Bierma-Zeinstra SM. Individual patient data meta-analysis of trials

investigating the effectiveness of intra-articular glucocorticoid injections in patients with

knee or hip osteoarthritis: an OA Trial Bank protocol for a systematic review. Systematic

reviews. 2013;2:54. doi: 10.1186/2046-4053-2-54. PubMed PMID: 23830482; PubMed

Central PMCID: PMC3707758

90 Pelletier JP, Cooper C, Peterfy C, Reginster JY, Brandi ML, Bruyere O, Chapurlat R,

Cicuttini F, Conaghan PG, Doherty M, Genant H, Giacovelli G, Hochberg MC, Hunter DJ,

Kanis JA, Kloppenburg M, Laredo JD, McAlindon T, Nevitt M, Raynauld JP, Rizzoli R,

Zilkens C, Roemer FW, Martel-Pelletier J, Guermazi A. What is the predictive value of MRI

http://www.ncbi.nlm.nih.gov/pubmed/23494470

http://www.ncbi.nlm.nih.gov/pubmed/23494470

Page 18 of 24


for the occurrence of knee replacement surgery in knee osteoarthritis? Annals of the

rheumatic diseases. 2013;72(10):1594-604. doi: 10.1136/annrheumdis-2013-203631.

PubMed PMID: 23887285

91 Motyl JM, Driban JB, McAdams E, Price LL, McAlindon TE. Test-retest reliability and

sensitivity of the 20-meter walk test among patients with knee osteoarthritis. BMC

musculoskeletal disorders. 2013;14(1):166. doi: 10.1186/1471-2474-14-166. PubMed PMID:

23663561; PubMed Central PMCID: PMC3661341

92 Lu B, Ahmad O, Zhang FF, Driban JB, Duryea J, Lapane KL, McAlindon T, Eaton CB. Soft

drink intake and progression of radiographic knee osteoarthritis: data from the osteoarthritis

initiative. BMJ open. 2013;3(7). doi: 10.1136/bmjopen-2013-002993. PubMed PMID:

23872291; PubMed Central PMCID: PMC3717463

93 Henrotin Y, Chevalier X, Herrero-Beaumont G, McAlindon T, Mobasheri A, Pavelka K,

Schon C, Weinans H, Biesalski H, Participants at the Hohenheim Consensus Conference in

August t. Physiological effects of oral glucosamine on joint health: current status and

consensus on future research priorities. BMC research notes. 2013;6:115. doi:

10.1186/1756-0500-6-115. PubMed PMID: 23531101; PubMed Central PMCID:

PMC3629992

94 Driban JB, Price LL, Lo GH, Pang J, Hunter DJ, Miller E, Ward RJ, Eaton CB, Lynch JA,

McAlindon TE. Evaluation of bone marrow lesion volume as a knee osteoarthritis

biomarker - longitudinal relationships with pain and structural changes: data from the

Osteoarthritis Initiative. Arthritis research & therapy. 2013;15(5):R112. doi: 10.1186/ar4292.

PubMed PMID: 24020939.

95 Bannuru RR, Vaysbrot EE, Sullivan MC, McAlindon TE. Relative efficacy of hyaluronic acid

in comparison with NSAIDs for knee osteoarthritis: A systematic review and meta-analysis.

Seminars in arthritis and rheumatism. 2013. doi: 10.1016/j.semarthrit.2013.10.002. PubMed

PMID: 24216297

96 McAlindon TE, Bannuru RR, Sullivan MC, Arden NK, Berenbaum F, Bierma-Zeinstra SM,

Hawker GA, Henrotin Y, Hunter DJ, Kawaguchi H, Kwoh K, Lohmander S, Rannou F, Roos

EM, Underwood M. OARSI guidelines for the non-surgical management of knee

osteoarthritis. Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society. 2014.

doi: 10.1016/j.joca.2014.01.003. PubMed PMID: 24462672.

97 Bannuru, R. R., N. E. Flavin, E. Vaysbrot, W. Harvey and T. McAlindon (2014). "High-

energy extracorporeal shock-wave therapy for treating chronic calcific tendinitis of the

shoulder: a systematic review." Ann Intern Med 160(8): 542-549.

98 Driban, J. B., M. F. Barbe, M. Amin, N. S. Kalariya, M. Zhang, G. H. Lo, A. M. Tassinari, D.

Harper, L. L. Price, C. B. Eaton, E. Schneider and T. E. McAlindon (2014). "Validation of

quantitative magnetic resonance imaging-based apparent bone volume fraction in peri-

articular tibial bone of cadaveric knees." BMC Musculoskelet Disord 15: 143.

99 Driban, J. B., C. B. Eaton, G. H. Lo, R. J. Ward, B. Lu and T. E. McAlindon (2014). "Knee

injuries are associated with accelerated knee osteoarthritis progression: Data from the

Osteoarthritis Initiative." Arthritis Care Res (Hoboken).

100Lu, B., J. B. Driban, J. Duryea, T. McAlindon, K. L. Lapane and C. B. Eaton (2014). "Milk

consumption and progression of medial tibiofemoral knee osteoarthritis: data from the

osteoarthritis initiative." Arthritis Care Res (Hoboken) 66(6): 802-809.

Page 19 of 24


101McAlindon, T., M. LaValley and B. Dawson-Hughes (2013). "Vitamin D supplementation in

patients with osteoarthritis--reply." JAMA 309(15): 1583-1584.

102McAlindon, T. E., R. R. Bannuru, M. C. Sullivan, N. K. Arden, F. Berenbaum, S. M. Bierma-

Zeinstra, G. A. Hawker, Y. Henrotin, D. J. Hunter, H. Kawaguchi, K. Kwoh, S. Lohmander,

F. Rannou, E. M. Roos and M. Underwood (2014). "Response to Letter to the Editor entitled

"Comments on 'OARSI guidelines for the non-surgical management of knee osteoarthritis'"."

Osteoarthritis Cartilage 22(6): 890-891.

103Pang, J., J. Driban, T. McAlindon, J. Tamez-Pena, J. Fripp and E. Miller (2014). "On the use

of coupled shape priors for segmentation of magnetic resonance images of the knee." IEEE

J Biomed Health Inform.

104Wang, C., M. D. Iversen, T. McAlindon, W. F. Harvey, J. B. Wong, R. A. Fielding, J. B.

Driban, L. L. Price, R. Rones, T. Gamache and C. H. Schmid (2014). "Assessing the

comparative effectiveness of Tai Chi versus physical therapy for knee osteoarthritis: design

and rationale for a randomized trial." BMC Complement Altern Med 14: 333.

105Zhang, M., J. B. Driban, L. L. Price, D. Harper, G. H. Lo, E. Miller, R. J. Ward and T. E.

McAlindon (2014). "Development of a rapid knee cartilage damage quantification method

using magnetic resonance images." BMC Musculoskelet Disord 15: 264.

106Fang Fang Zhang, Jeffrey B Driban, Grace H Lo, Lori Lyn Price, Sarah Booth, Charles B

Eaton, Bing Lu, Michael Nevitt, Becky Jackson, Cheryl Garganta, Marc C Hochberg, Kent

Kwoh, and Timothy E McAlindon Vitamin D Deficiency Is Associated with Progression of

Knee Osteoarthritis J. Nutr. 2014; 144:2002-2008 doi:10.3945/jn.114.193227

b ) O t h e r p a p e r s p r e s e n t i n g p r i m a r y d a t a

1 U.S. Patent Application 09/560,597 Method For Conducting Clinical Trials Over The

Internet – Published 07/31/2007

c ) B o o k c h a p t e r s

1. Dieppe P, Cushnaghan J, McAlindon T. Epidemiology, Clinical Course and Outcome of

Knee Osteoarthritis. In - Articular cartilage and Osteoarthritis, SD Kuettner et al, Raven Press, New York 1992.

2. McAlindon TE, Allaire SA. Systemic Lupus Erythematosus. In – Primary Care: A Collaborative Practice. Eds Bailey PP, Buttaro TM, Oas KH, Trybulski J. Mosby, St Louis, 1999.

3. Allaire SA, McAlindon TE. Rheumatoid Arthritis. In – Primary Care: A Collaborative Practice. Eds Bailey PP, Buttaro TM, Oas KH, Trybulski J. Mosby, St Louis, 1999.

4. McAlindon TE. Regional Musculoskeletal Pain: The Knee. In – Bailliere’s Best Practice & Research: Clinical Rheumatology. Eds Croft P, Brooks PM. Bailliere Tindall Press 1999; 13(2);329-44.

5. McAlindon TE. Osteoarthritis: Role of Nutrition and Dietary Supplement Interventions. In – Primary and Secondary Preventive Nutrition, pp 291-305 Eds Bendich A, Deckelbaum R. Humana Press, Totowa, NJ 2000.

6. McAlindon T. Why are Clinical Trials of Glucosamine No Longer Uniformly Positive?

In – Rheumatic Disease Clinics of North America: Osteoarthritis. Ed Brandt KD, Philadelphia, 2003.

Page 20 of 24


7. McAlindon TE. Nutritional Therapies. In – Osteoarthritis, Second Edition, pp 289-292, Eds Brandt & Doherty, Oxford University Press, Oxford, UK, 2003.

8. McAlindon TE. Mechanisms by which micronutrients may influence osteoarthritis. In – Osteoarthritis, Second Edition, pp 293-297, Eds Brandt & Doherty, Oxford University Press, Oxford, UK, 2003.

9. McAlindon TE. Osteoarthritis. In – Clinical Handbook of Nutrition and Aging, Eds Bales CW & Ritchie C. Humana Press, Totowa, NJ, 2004.

10. McAlindon TE, Lo GH. Nutritional and Nutritional Supplement Interventions for Osteoarthritis. In - Osteoarthritis, Eds Sharma and Berenbaum. 2007

11. De Pablo P, McAlindon TE. Nutrition and Nutritional Supplements and Osteoarthritis. In - Nutrition and Rheumatic Disease, Editors: Meydani, Goldberg, Coleman, Series Editor Bendich, Humana Press, 2007

12. McAlindon TE. Osteoarthritis. In – Clinical Handbook of Nutrition and Aging, 2nd Edition Eds Bales CW & Ritchie C. Humana Press, Totowa, NJ, 2008.

13. McAlindon T and Ward RJ. Osteonecrosis. In – RHEUMATOLOGY, 5th Edition, pp 1815-1823, Eds Hochberg MC, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH, Mosby Elsevier, Philadelphia, PA 2011.

d ) I n v i t e d r e v i e w s

1. McAlindon TE, Dieppe PA. Arthritis in the elderly. Medicine International 1990;74:3095-8.

2. McAlindon TE, Dieppe PA. Osteoarthritis. Care of the Elderly 1990;2:201-203.

3. McAlindon TE, Dieppe PA. Disorders of the Shoulder in Elderly People. BMJ 1990;300:1341.

4. McAlindon TE, Felson DT. Identifying individuals at risk for arthritis. IM Internal Medicine 1996;17:17-28.

5. McAlindon TE. Does Diet Affect Potential for Osteoarthritis? (Q & A) Musculoskeletal Medicine 1999;16:673.

6. McAlindon T. Update on the Epidemiology of Systemic Lupus Erythematosus: New Spins on Old Ideas. Curr Op Rheumatol 2000;12:104-112.

7. Tim McAlindon. Epidemiologie de l’Arthrose. La Revue De Praticien 2000:50. 8. Felson DT, Lawrence RC, Dieppe PA, Hirsch R, Helmick CG, Jordan JM, Kington RS, Lane

ME, Nevitt MC, Zhang Y, Sowers M, McAlindon T, Spector TD, Poole AR, Yanovski SZ, Ateshian G, Sharma L, Buckwalter JA, Brandt KD, Fries JF. Osteoarthritis: New Insights. Part 1: The Disease and its Risk Factors. Ann Intern Med 2000:133(8):635-646.

9. David T. Felson, Marc C. Hochberg, Timothy McAlindon, Paul A. Dieppe. Osteoarthritis: New Insights. Part 2: Treatment Approaches. Ann Intern Med 2000:133(9):726-737.

10. Baker K, McAlindon TE. Exercise for Knee Osteoarthritis. Curr Opin Rheumatol 2000:12:456-463.

11. McAlindon TE. Can Diet Affect The Risk and Progression of Osteoarthritis? Women’s Health 2000:3:208-214.

12. McAlindon TE. Glucosamine and Chondroitin for Osteoarthritis? Bull Rheum Dis., Vol. 50, No. 7, 2001.

13. Biggee BA, McAlindon T. Glucosamine for osteoarthritis: part I, review of the clinical evidence. Med Health R I 2004;87: 176-9

14. Biggee BA, McAlindon T. Glucosamine for osteoarthritis: part II, biologic and metabolic controversies. Med Health R I 2004;87:180-1

Page 21 of 24


15. Arabelovic S, McAlindon TE. Considerations in the treatment of early osteoarthritis. Curr Rheumatol Rep;2005:29-35

16. Timothy E. McAlindon and Beth Anne Biggee. Nutritional Factors and Osteoarthritis: Recent Developments. Curr Opin Rheumatol 17:647-652, 2005.

17. Timothy E. McAlindon. Neutraceuticals: Do they work and when should we use them? Best Practice & Research Clinical Rheumatology (Osteoarthritis) 20:99-115, 2006.

18. McAlindon TE, Driban JB, Lo GH: Osteoarthritis year 2011 in review: clinical. Osteoarthritis Cartilage 2012, 20(3):197-200.

19. McAlindon T. Osteoarthritis Research Society International (OARSI) Classification and Guidelines. HSS journal : the musculoskeletal journal of Hospital for Special Surgery 2012, 8(1):66-67.

20. McAlindon TE, Bannuru RR: Osteoarthritis: Is viscosupplementation really so unsafe for knee OA? Nat Rev Rheumatol 2012, 8(11):635-636.

e ) E d i t o r i a l s

1. McAlindon TE, Dieppe PA. Osteoarthritis: Definitions and Criteria. Ann Rheum Dis 1989;48:531-2.

2. McAlindon TE, Dieppe PA. The Medical Management of Osteoarthritis of the Knee: An Inflammatory Issue? Brit J Rheum 1990;29:471-473.

3. McAlindon TE, Felson DT. Nutritional Risk Factors for Knee Osteoarthritis. Ann Rheum Dis 1997;56:397-402.

4. Felson DT, McAlindon TE. Glucosamine and Chondroitin for Osteoarthritis: To Recommend or Not to Recommend? Arthr Care Res 2000;13:197-182.

5. McAlindon T. Glucosamine for Osteoarthritis: Dawn of a New Era? Lancet 2001;357:247-8.

6. McAlindon TE. Is treatment with chondroitin efficacious for osteoarthritis? Nat Clin Pract Rheumatol 2007;3(11):606-7.

7. McAlindon T. 2007 OARSI Recommendations for the Management of Hip and Knee Osteoarthritis: Towards Consensus? Osteoarthritis and Cartilage 2008;16:636-7.

8. McAlindon TE, Bannuru RR: OARSI recommendations for the management of hip and knee osteoarthritis: the semantics of differences and changes. Osteoarthritis Cartilage 2010, 18(4):473-475.

f ) C a s e r e p o r t s

1. McAlindon TE. Disseminated Intravascular Coagulation Following Phenelzine Overdose. BMJ 1986;293:1103.

2. McAlindon TE, Ferguson IT. Mononeuritis Multiplex and Occipital Infarction Complicating Giant Cell Arteritis. British J Rheumatol 1989;28:257-8.

3. Hanson JA, McAlindon TE. Possible Dangers of Cold Water. Brit J Rheumatol 1993;32:525-6.

4. McAlindon TE, MacFarlane D, Ward S, Mathews JA. Transient Regional Osteoporosis Presenting as a Septic Arthritis. Postgraduate Medical Journal 1993;69:871-873.

5. Snowden MJ, McAlindon TE, Morosan CG, Lo GH. Small vessel vasculitis in a patient with botryomycosis. J Rheumatol 2006;33:2545-7

Page 22 of 24


g ) B o o k s A u t h o r e d / B o o k s e d i t e d – n / a

h ) T h e s e s

‘Knee Joint Failure’; Doctorate in Medicine, Southampton University, UK, 1993

i ) S e l e c t e d R e c e n t P u b l i s h e d A b s t r a c t s

k ) I n v i t e d L e c t u r e s

1. Stepping Away From OA: A Scientific conference on the prevention of onset, progression and disability of osteoarthritis. Nation Institute of Arthritis and Musculoskeletal and Skin Diseases, July 23-24 1999.

a. Nutritional Factors b. Nutriceuticals c. Complementary and Alternative Medicine (Public Session)

2. ARHP Annual Meeting Nov 1999, “Radiology of Rheumatic Disease” 3. ‘Epidemiology of Osteoarthritis’ Conference on disease modification in OA. MonteCarlo,

1/29/00 4. ‘Risk factors for lupus among Black women.’ Rheumatology Grand Rounds, Rheumatology

Section, Yale, 5/24/00 5. Boston Dept. of Public Health Lupus Conference, 6/24/00, ‘Risk factors for SLE among

Black Women’ 6. ‘Glucosamine and Chondroitin for Osteoarthritis’ Orthopedic Grand Rounds, Boston Medical

Center, Nov 2000 7. ‘New Advances in the Treatment of Arthritis’, New Advances in Arthritis Treatment,

Massachusetts Rehabilitation Commission/ Arthritis Foundation, Boston Nov 2000 (i) ‘Risk factors for OA progression’ (ii) ‘Alternative treatments for OA’.Georgia

Society for Rheumatology. April 2001. 8. “Glucosamine and Chondroitin: A Critical Review of the Evidence”. Nutracon 2001

Conference; San Diego July 2001. 9. “Nutritional support for osteoarthritis – overview and latest findings”, Glucosamine, Kan man

spise sig fra slidgigt? [Industry-sponsored conference on glucosamine] August 20th, 2001. 10. ‘Can clinical trials be performed entirely over the Internet’, Session on ‘Using the Internet to

Conduct Rheumatology Research’, Annual Meeting of the International League of Associations for Rheumatology (ILAR), Edmonton, August 2001.

11. ‘Can Clinical Trials be performed entrirely over the Internet?’ Seminar, Center for Drug Evaluation & Research, Food and Drug Administration, Rockville, MD, October 2001.

12. ‘Internet-based Clinical Trials’ – Clinical Research in the Department of Medicine, Dept. of Medicine Retreat, October 2nd, 2001.

13. ‘Diet and Arthritis’ 9th Annual Symposium on Geriatric Research and Healthcare Policy - Facing Aging or Changing its Face - Research & Training Institute of the Hebrew Rehabilitation Center for the Aged, October, 2001.

14. ‘Methodological Obervations From An Online Trial’. Web-based Clinical Trials Workshop, Sponsored by Bioforums and IQPC, Boston, October 29-30th, 2001. .

15. ‘Nutritional remedies for osteoarthritis: the glucosamine/chondroitin story’. General Internal Medicine Section Rounds, Boston University School of Medicine, January 9th, 2002.

Page 23 of 24


16. ‘Nutritional Factors and Osteoarthritis. Department of Family Medicine Noon Conference, Boston University School of Medicine, Tuesday, March 19th, 2002.

17. ‘Using the Internet to Conduct Clinical Trials’, Boston University School of Medicine Clinical Trials Management Certificate Program, Friday, April 26, 2002.

18. ‘An Evaluation Of Glucosamine For The Treatment Of OA’ – Symposium On Controversies And Practical Issues In The Management Of Osteoarthritis, Philadelphia, May 2002

19. ‘Nutritional Risk Factors for Osteoarthritis Incidence and Progression’ Brown University Center for Primary Care and Prevention Research Forum. 10/08/2002

20. ‘On-Line Clinical Trials’ – Certificate in Clinical Trials Management Program, Sponsored by the Schools of Medicine and Public Health and the Center for Professional Education at Boston Univeristy, March 2002 & March 2003.

21. Hot topics in osteoarthritis research. Medical Grand Rounds, Tufts New England Medical Center. May 23 2003.

22. Osteoarthritis.ARHP Annual Scientific Meeting 2003. 23. Arthritis Grand Rounds Guest Lecturer, Massachusettes General Hospital, Boston MA,

March 9, 2004. 24. Rheumatology Conference Guest Lecturer, Lahey Clinic, Burlington, MA, March 30, 2004. 25. ‘Glucosamine and Chondroitin Sulfate in Osteoarthritis.’ Rheumatology Grand Rounds,

Division of Rheumatology, Roger Williams Medical Center, June 15, 2004. 26. ACR Annual Meeting, October 2004. “Barometric Pressure and Ambient Temperature

Influence Osteoarthritis Pain. Results Of A National Web-Based Prospective Study.” 27. ACR Communications and Marketing Committee Media Presentation, “Barometric Pressure

and Ambient Temperature Influence Osteoarthritis Pain. Results Of A National Web-Based Prospective Study,” ACR/ARHP Annual Meeting, October 2004.

28. “Current Concepts In Osteoarthritis.” Rheumatology Grand Rounds, Beth Israel Deaconess Medical Center, Boston, MA, November 12, 2004.

29. “Joint Physiology, Glucosamine and Chondroitin.” The Viactiv Bone and Joint Health Summit, McNeil Nutritionals, LLC, a Johnson & Johnson Company, New York, New York, March 31, 2005.

30. “Separating Facts and Fiction in Arthritis.” Yale Rheumatology Symposium, New Haven, Connecticut, April 6, 2005.

31. “Internet-based Clinical Trial.” Clinical Decision Making Seminar, Tufts-New England Medical Center, Boston, MA, September 20, 2005.

32. “Internet Use in Clinical Research.” General Clinical Research Center Basic Tools for Clinical Research Fall Workshop 2005, Tufts-New England Medical Center, Boston, MA, October 25, 2005.

33. “Fact and Fiction in Rheumatology: Glucosamine and the Weather.” Rheumatology Grand Rounds, University of Massachusetts Medical School, Worcester, MA, December 2, 2005.

34. Meteorologic Effects On Arthritis Pain - Tufts Headache & Facial Pain Rounds, March 28, 2007

35. Osteoarthritis: Novel Treatments – Meet The Professor – American College of Rheumatology Annual Meeting, Nov 2007, 2008, 2009

36. Vitamin D And Osteoarthritis - International Academy of Nutrition and Aging (IANA), Boston, November 2007

37. OA: Novel treatment perspectives from clinical research. MGH Rheumatology Grand Rounds, Nov 2009

38. OA: Novel treatment perspectives from clinical research. BIDMC Rheumatology Grand Rounds, Apr 2010

Page 24 of 24


39. “Can clinical trials be performed entirely over the Internet? Experience with the Online Glucosamine Trial.” Novartis, Innovation in Science & Technology Day, Congress Center Basel, Switzerland, October 19, 2010

40. “Setting up Clinical Trials.” OARSI Breakfast Workshop B, San Diego, California, September 18, 2011.

41. “Clinical.” Plenary Session 4 – Year in Review, OARSI, San Diego, California, September 18, 2011.

42. “MSUS”. Boston University, Grand Rounds. December 2012. 43. “Innovations in Osteoarthritis Therapy”. Tobey Hospital, The Southcoast Hospitals Group.

December 2012

l ) N o n - p r i n t P u b l i c a t i o n s

1. Lupus, About Health with Jeanne Blake (health program distributed local cable channels, 1996.

2. Arthritis and Vitamins, Healthweek, WGBH-TV, August 1997. 3. Lupus, WLVI-TV News, October 1999. 4. Glucosamine, WBZ-TV News, February 2001. 5. Discovery Channel ‘Arthritis’ 2001 6. Channel 7 News Sept 2009 Interview concerning Lymphostat-B for SLE.

Documents

TUFTS UNIVERSITY SCHOOL OF MEDICINE …momi.de/symposium/wp-content/uploads/2018/02/CV... · TUFTS UNIVERSITY SCHOOL OF MEDICINE ... 2/1/83 - 7/31/83 House ... 9 October 1998: General