Tuberculin Test in Children

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    Paediatrica IndonesianaVOLUME 51 NUMBER 6November

    Original Article

    Paediatr Indones, Vol. 51, No. 6, November 2011 311

    Risk factors for positive tuberculin tests in children

    Purnomo Sidhi, 1 Dwi Wastoro Dadiyanto, 1 Suhartono 2

    AbstractBackground 7XEHUFXORVLV 7% LV D FKURQLF LQIHFWLRXV GLVHDVHDQG D SXEOLF KHDOWK SUREOHP 7KH :RUOG +HDOWK 2UJDQL]DWLRQ:+2 GHFODUHG7% WREH DJOREDO HPHUJHQF\ EHFDXVHRI FXUUHQWO\increasing rates of disease and drug resistance. Two million peopledie annually because of TB. Children are one of the highest groupsat risk for TB infection. An effort to define risk factors is neededfor effective intervention.Objective To identify risk factors for positive tuberculin testsin children.

    Methods This case control study was done in elementary schoolFKLOGUHQ DJHG \HDUV LQ DUHDV VHUYHG E\ WKUHH FRPPXQLW\KHDOWK FHQWHUV LQ 6HPDUDQJ 7ZHQW\ QLQH VXEMHFWV ZHUH 0DQWRX[SRVLWLYH DQG RWKHUV VHUYHG DV FRQWUROV &RQVHFXWLYH VDPSOLQJZDV XVHG IRU DOO QHJDWLYH 0DQWRX[ WHVW UHVXOWV 3XOPRQDU\

    TB was diagnosed using the TB scoring system, including theMantoux test. Statistical bivariate and multivariate analyseswere performed.Results History of household TB contact as a risk factor forpositive tuberculin test in children resulted in an OR of 3.76

    &, WR 3 +LVWRU\ RI LOOQHVV DW WKH WLPHRI WHVWLQJ UHVXOWHG LQ DQ 25 RI &, WR3 7KH SUREDELOLW\ RI SRVLWLYH WXEHUFXOLQ WHVWLQJ ZDVif both these variables were positive.Conclusion History of household TB contact and the history of illness at the time of testing were risk factors for positive tuberculintests in children. [Paediatr Indones. 2011;51:311-5] .

    Keywords: tuberculosis contact, tuberculin test,children

    From the Department of Child Health, Medical School, Diponegoro8QLYHUVLW\ .DULDGL +RVSLWDO 6HPDUDQJ ,QGRQHVLD1 From the Faculty of 3XEOLF +HDOWK 'LSRQHJRUR 8QLYHUVLW\ 6HPDUDQJ ,QGRQHVLD

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    3ulmonary tuberculosis, also known as

    tuberculosis 7% LV D FKURQLF LQIHFWLdisease caused by Mycobacterium tuberculosis.These bacteria have caused more disease

    LQ UHFHQW GHFDGHV DQG KDYH EHHQ FODVVemerging disease. 1 7KH :RUOG +HDOWK 2UJDQL]DW:+2 HVWLPDWHV WKDW PLOOLRQ QHZ FDV

    7% KDYH DULVHQ LQ FKLOGUHQ ZRUOGZLGH Dchildren younger than 15 years die annually. Indeveloping countries, the risk of TB infections inFKLOGUHQ LV DQG 7% FDXVHV PRUWDOLWchildren. 3 WHO stated that Indonesia is one of the

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    %DVHG RQ WXEHUFXOLQ VNLQ WHVW UHVXformulate a tuberculin index as a guide to understandthe extent of TB infections to measure the prevalenceof tuberculosis infection and ARTI (Annual Risk of 7XEHUFXORVLV ,QIHFWLRQ LQ FKLOGUHQ6,7 An IndonesianVXUYH\ LQ VKRZHG WKDW SRVLWLYH DFEDFWHULD $)% SUHYDOHQFH ZDV ZKLOSRVLWLYH $)% LQFLGHQFH ZDV ZLWK VHYregional variations. 6 Children with tuberculosismight show a positive tuberculin skin test with orwithout apparent clinical, radiographic, or laboratory

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    Purnomo Sidhi et al:Risk factors for positive tuberculin tests in children

    Paediatr Indones, Vol. 51, No. 6, November 2011 315

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