Tropis_Tissue helminth6_capillaria, fasciola.pdf

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    Parasite of rodents, dogs, and monkeys

    Infected if eat raw meat

    6/18/2012 S. Wahyuni, Parasitology Dept, Medical Faculty, Unhas 1

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    In a host the ova are deposited in the liver

    fully embryonated within 30 days

    a new host eats infected liver

    the larvae after piercing the intestinal wall migrate to

    t e ver

    become mature in 4 weeks

    6/18/2012 S. Wahyuni, Parasitology Dept, Medical Faculty, Unhas 2

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    Pathogenicity

    inflammatory reaction in the liver with theroduction of fibrous connective tissue

    in heavy infections extensive tissuedestruction & he atic cirrhosis

    microscopic examination of the liver at

    6/18/2012 S. Wahyuni, Parasitology Dept, Medical Faculty, Unhas 3

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    Classified as trematodes The sheep liver fluke

    can infect humans

    accidentally epa ca : up o x

    mm

    Reside in the large biliary

    ducts of the mammalianhost.

    Worldwide distribution

    6/18/2012 S. Wahyuni, Parasitology Dept, Medical Faculty, Unhas 4

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    distinct operculum inupper end of the

    ellipsoidal size 120-150 x 63 to 90 m.

    . The operculum can

    be opened (egg C),

    ,operculum

    have a thin shell which is slightlythicker at the abopercular end.

    6/18/2012 S. Wahyuni, Parasitology Dept, Medical Faculty, Unhas 5

    passe unem ryona e .

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    genus Lymnae4 months

    6/18/2012 S. Wahyuni, Parasitology Dept, Medical Faculty, Unhas 6

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    acute hase (caused b the mi ration of the

    immature fluke through the hepaticparenchyma): abdominal pain, hepatomegaly,fever vomitin diarrhea urticaria &eosinophilia can last for months.

    chronic phase (caused by the adult fluke within

    and reflect intermittent biliary obstruction andinflammation.

    ccas ona y, ectopc ocatons o n ecton sucas intestinal wall, lungs, subcutaneous tissue,and har n eal mucosa) can occur.

    6/18/2012 S. Wahyuni, Parasitology Dept, Medical Faculty, Unhas 7

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    6/18/2012 S. Wahyuni, Parasitology Dept, Medical Faculty, Unhas 8

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    E s: in the stools or in material obtained b

    duodenal or biliary drainage. False fascioliasis (pseudofascioliasis) refers to

    t e presence o eggs n t e stoo resutng notfrom an actual infection but from recent ingestion

    avoided by having the patient follow a liver-freediet several days before a repeat stool

    examna on. Antibody detection tests are useful especially in

    6/18/2012 S. Wahyuni, Parasitology Dept, Medical Faculty, Unhas 9

    ,.