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TREATMENT PLANNING PHOTONS & ELECTRONS
Karen P. Doppke 3/20/2007
Regions of Radiation Field Considered in Dose Calculations
DOSE TO A POINT IN TISSUE
Major Processes that Effect Dose in Tissue from Photon Beams
Inverse Square Law
Photon Attenuation
Photon Scatter
Dose Calculation Methods Used to Determine Dose at a Point in a Patient
Correction Based Methods
% Depth Dose Calculations
Tissue Maximum/Phantom Ratios
Tissue-Air Ratios
Model Based Methods
Pencil Beam Methods
Convolution Superposition
Monte Carlo Calculations
The General Form of Equation Used to Calculate Dose at Depth in the Patient
TPR (d, r, h) = Dose at Depth / Dose at Reference/Max
10 Mv X-ray Beam
Isodose Curves High Energy
Variation in Dose for Various Energy Beams
COMPARE MONTE CARLO DOSES IN LUNG
Comparison Dose Distribution 6 MV X-Rays
Conformal Planning Process
PATIENT DATA SET/SCT, MRI, PET
DEFINATION OF TARGET AND NORMAL TISSUES
PRESCRIPTION DOSE and FRACTIONATIONTOTAL DOSE TO VOLUMES DOSE TO NORMAL TISSUES
EXAMPLE OF A CONFORMAL PLAN
The prescription should include the total dose to the target volumes, the fractionation, a statement of the expansion of the GTV to the CTV and PTV.
The dose limits to the normal tissues that are near the site of treatment need to be defined.
ICRU 62
EXAMPLE OF TREATMENT VOLUMES
TREATMENT VOLUMES
GTVGTV
CTVCTV
ITVITV
PTVPTV
NORMAN TISSUES NEAR TREATMENT SITE
SPINAL CORD < ~45 Gy
LIVER <~25Gy/100%, 30Gy/35%, 35Gy/25%
KIDNEYS <~23Gy/66%
LUNG <~30Gy/40%, 60Gy/20%
HEART <~30Gy/100% LV, 45Gy/100% (atrium)
AP/PA OPPOSED FIELDS
DVH FOR TISSUES AP/PA
CTVPTVLiver
Lung RT Kidney RTHeart
FOUR FIELD PLAN AP/PA/RLAT/LLAT
DVH 4 FIELD PLAN
CTVPTVLiver
HeartKidney RTLung RT
5 FIELD PLANE AP/RA/RP/LP/LA
DVH 5 FIELD PLAN
CTVPTVLiverLung RTHeart Kidney RT
CTVLung RTKidney RT
Stereotactic Radiosurgery 1905: Introduction of stereotactic
equipment 1908: Mapping of brain in 3 planes 1918: First stereotactic frame for humans
in London 1940: Greatest strides in intracranial
applications began
Stereotactic Radiosurgery1982: Modified Linear Accelerator
Stereotactic RadiosurgerySRS Frame Placement
STEROTACTIC RADIATION THERAPY SRT
Fractionated Stereotactic Radiation Therapy
Fractionated Stereotactic Radiation Therapy(SRT) combines the target and dose localization characteristics of SRS with the biologic advantages of dose fractionization
STEROTACTIC RADIATION SURGERY SRS
Fractionated Stereotactic Radiation Therapy
Fractionated Stereotactic Radiation Therapy