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Chemical Heritage Foundation Transmutations NO. 4 FALL 2008 Treasure the past Educate the present Inspire the future Illuminates Impact of 20th-Century Science Today’s typical consumer expects effective medicines, a wide range of safe foods, ever-faster communi- cations, and myriad other modern conveniences. Without the chemical and molecular sciences these expectations could not be met, much less exceeded, and the story of human development would greatly differ from the one we currently know. Yet the work of chemists and chemical engineers is quickly taken for granted. Raymond J. Giguere, a professor of chemistry at Skidmore College, recognized this lack of public awareness and set out to illuminate the impact of significant molecules as well as the science that enabled their discovery. The result is Molecules That Matter, a fascinating traveling exhibition that showcases ten organic molecules that profoundly altered modern life. The scientific and sociological implications of each molecule are explored through contemporary art, historical artifacts, and large-scale molecular models. Identifying ten molecules that best capture scientific achievement in the 20th century was not a quick or easy process. In 2005 Giguere and his colleagues at Skidmore’s Frances Young Tang Teaching Museum and Art Gallery invited CHF to collaborate on the project. A committee of ten professionals from higher education, industry, and CHF then ruminated on molecules with far-ranging significance. The final selection, reviewed by chemistry Nobel laureates Roald Hoffmann and Dudley Herschbach, is a balanced range of compounds that includes pharmaceuticals, consumer-industrial polymers, and unique molecules: aspirin, isooctane, penicillin G, polyethylene, nylon 6,6, DNA, progestin, DDT, Prozac, and buck- minsterfullerene (also known as the buckyball). The committee associated each molecule with one decade of the 20th century according to date of discovery or period of impact. Once the molecules were chosen, a team of CHF and Skidmore staff members began performing additional research, commissioning and collecting art, tracking down pertinent artifacts, and working with fabricators on the molecular models, which are 2.5 billion times larger than actual size. This juxtapo- sition of objects makes Molecules That Matter a one-of-a-kind experience that blurs the boundaries of art, natural science, and social science. M ol ec ul es THAT MATTER A one-of-a-kind experience that blurs the boundaries of art, natural science, and social science. continued on page 8 Molecular models suspended in the Francis Young Tang Teaching Museum and Art Gallery at Skidmore College. Photo by Art Evans.

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Page 1: Transmutations Newsletter

Chemical Heritage

Foundation TransmutationsN O . 4 � FA L L 2 0 0 8 Treasure the past Educate the present Inspire the future

Illuminates Impact of20th-Century Science

Today’s typical consumer expects effective medicines,

a wide range of safe foods, ever-faster communi-

cations, and myriad other modern conveniences.

Without the chemical and molecular sciences these

expectations could not be met, much less exceeded,

and the story of human development would greatly

differ from the one we currently know. Yet the work

of chemists and chemical engineers is quickly taken

for granted.

Raymond J. Giguere, a professor of chemistry at Skidmore

College, recognized this lack of public awareness and set out

to illuminate the impact of significant molecules as well as the

science that enabled their discovery. The result is Molecules

That Matter, a fascinating traveling exhibition that showcases

ten organic molecules that profoundly altered modern life.

The scientific and sociological implications of each molecule

are explored through contemporary art, historical artifacts,

and large-scale molecular models.

Identifying ten molecules that best capture scientific

achievement in the 20th century was not a quick or easy process.

In 2005 Giguere and his colleagues at Skidmore’s Frances

Young Tang Teaching Museum and Art Gallery invited CHF to

collaborate on the project. A committee of ten professionals

from higher education, industry, and CHF then ruminated on

molecules with far-ranging significance.

The final selection, reviewed by chemistry Nobel laureates

Roald Hoffmann and Dudley Herschbach, is a balanced range of

compounds that includes pharmaceuticals, consumer-industrial

polymers, and unique molecules: aspirin, isooctane, penicillin G,

polyethylene, nylon 6,6, DNA, progestin, DDT, Prozac, and buck-

minsterfullerene (also known as the buckyball). The committee

associated each molecule with one decade of the 20th century

according to date of discovery or period of impact.

Once the molecules were chosen, a team of CHF and

Skidmore staff members began performing additional research,

commissioning and collecting art, tracking down pertinent

artifacts, and working with fabricators on the molecular models,

which are 2.5 billion times larger than actual size. This juxtapo-

sition of objects makes Molecules That Matter a one-of-a-kind

experience that blurs the boundaries of art, natural science, and

social science.

MoleculesTHAT MATTER

A one-of-a-kind

experience

that blurs the

boundaries

of art, natural

science, and

social science.

c o n t i n u e d o n p a g e 8Molecular models suspended in the Francis Young Tang TeachingMuseum and Art Gallery at Skidmore College. Photo by Art Evans.

Page 2: Transmutations Newsletter

2

exhibition about ten organic molecules that changed the

course of the 20th century. You can read more about the

latter on page 1, but I also urge you to visit CHF and see

firsthand how impressive these installations really are.

And that is not the only way to stay involved! Such big

finishes do not mean it is time to take a break. Instead CHF

is seizing the opportunity for new beginnings, and I hope

you will join us.

As you read this, we are putting the finishing touches

on CHF’s new strategic plan. The document that lays out this

plan, “Creating the Future,” represents the efforts and imag-

ination of many people, but I also seek the counsel of the

Transmutations

Treasure the past Educate the present Inspire the future

Writer and Coordinator : Margo Bresnen

Editor : Mary El len Burd

Design: SnyderCreat ive

Off ice of Advancement

Director of Advancement: Rick Sherman

Phone: 215-873-8254 . Fax: 215-629-5254

E-mai l : rsherman@chemheri tage.org

CHF General Information

315 Chestnut Street . Phi ladelphia, PA 19106

Phone: 215-925-2222 . Fax: 215-925-1954

www.chemheri tage.org

Open to the public: Monday–Friday, 10:00 a.m.–4:00 p.m.

N O . 4 � FA L L 2 0 0 8

Chemical Heritage Foundation

A Letter from the President and CEO

As we near the end of 2008, my natural inclination is to

notice all that CHF has achieved in the last several months.

Since becoming CHF’s second president on 1 January, I have

seen many exciting events unfold from a front-row seat.

For instance, this fall brings the triumphant close of CHF’s

25th Anniversary Initiative, the most successful campaign in

our organization’s history, in which we have exceeded our

$75 million goal thanks to the generous support of our many

friends (for more information, see page 14). Your contributions

encourage us to keep up the good work, and for that I extend

my gratitude.

Under the category of good work falls CHF’s other notable

accomplishment in 2008: the opening of our new museum

and conference center. Ten years of hard work have paid

off in CHF’s magnificent new galleries, home to Making

Modernity, the permanent exhibition that highlights the

untold story of the chemical and molecular sciences, and,

for this season only, Molecules That Matter, a traveling

Above: Thomas R. Tritton.Photo by Douglas A. Lockard.

Right: Molecules That Matter in CHF’s Clifford C. Hach Gallery.

Photo by Gregory Tobias.

Page 3: Transmutations Newsletter

3

entire CHF community. I therefore invite you to read a draft of

“Creating the Future” and to get back to me with reactions,

comments, critique, suggestions, and any other forms of

wisdom you would like to convey. Your advice will inform

my own thinking as well as the final version of the plan,

providing it with the strongest vision for CHF’s future directions

and emphases. To request a copy and to offer feedback, write

to [email protected].

While CHF is a relatively small organiza-

tion, small does not describe the scope of

our ambition. We do a lot; so much, in fact,

that it is difficult to explain our essence in

short and simple statements, but we are

giving it a try. We are reworking our mission

statement, and we are refocusing around

three central themes—collections, education,

and policy—that will lend CHF the most

relevance in the chemical and molecular

sciences, technologies, and industries as well as in the wider

world. We are proving that CHF’s complex and unique nature

is exactly what keeps us vital.

I am highly confident in CHF’s ability to forge a path

for growth that proves as compelling as our history. I have

already asked the staff to accept this new challenge,

and now I extend the invitation to you. Together we have

accomplished a great deal, but our work is never done.

Realizing the next level of our potential depends on your

continued enthusiasm and support.

Please stay tuned for updates on our progress through

this newsletter and other sources. And thank you again for all

that you have done and will continue to do to sustain CHF.

Thomas R. Tritton

Below: Archival objects enhance the timeline in CHF’s installationof Molecules That Matter. Bottom: Vials of molecules at theentrance to the Hach Gallery. Photos by Gregory Tobias.

Page 4: Transmutations Newsletter

4

He also became an active philanthropist and strong advocate

of civic responsibility, known especially for his work on behalf

of medical facilities and youth organizations.

Current and former senior executives of Rohm and Haas

and many Haas family friends turned out in May to honor

John Haas in CHF’s new E. I. du Pont Conference Center.

A premier suite overlooking Independence National Historical

Park was dedicated as the Otto Röhm and Otto Haas

Conference Room.

Rohm and Haas CEO Rajiv L. Gupta and CHF president

and CEO Thomas R. Tritton remarked on John Haas’s many

years with the company, his philanthropy in the Philadelphia

region and beyond, and his long involvement with CHF,

which dates to its earliest stages. For more than two

decades since, John Haas has continuously served on

CHF’s advisory boards and development committees and

generously given of his time, resources, and knowledge.

We thank John Haas and those who contributed in

his honor to establish the Otto Röhm and Otto Haas

Conference Room.

Otto Röhm, a chemist, and Otto Haas, a businessman, formed

a partnership in 1909 to manufacture and sell a unique

chemical product to the Philadelphia-based tanning industry.

Rohm and Haas Company quickly became a leader in acrylic

chemistry, developing Plexiglas, paint emulsifiers, coatings,

adhesives, and other key materials.

Now the once-tiny firm is one of the world’s top specialty

materials companies, with more than 100 locations in 25

countries, over 15,000 employees, and sales approaching

$10 billion. And next year Rohm and Haas will celebrate its

100th anniversary in the United States.

One critical component in Rohm and Haas’s growth and

success is the thoughtful stewardship of John C. Haas, the

younger son of Otto Haas. Educated as a chemical engineer

at the Massachusetts Institute of Technology, John Haas

joined the company in 1942. Over the next 50 years he served

Rohm and Haas in many capacities, including director of per-

sonnel, executive vice president, and chairman of the board.

Premier Conference Suite Dedicated in Honor of John C. Haas

Above: The Otto Röhm and Otto Haas Conference Room at CHF.Top: John C. Haas, right, enjoys the event with, from left, his son

Lenny, wife Chara, and son David. Photos by Douglas A. Lockard.

Page 5: Transmutations Newsletter

5

In recent years CHF has delivered valuable content to televi-

sion viewers. In 2006 the Science Channel’s series 100

Greatest Discoveries, hosted by Bill Nye, featured CHF in

its “Chemistry” episode. In February 2007 public television

stations nationwide aired the NOVA special “Forgotten

Genius,” a CHF collaboration with WGBH and Moreno/Lyons

Productions about the life of scientist Percy Julian. And last

October the PBS series Wired Science examined chemistry

sets from CHF’s collections in its premiere episode.

But CHF also strives to reach people who look to other,

newer sources for programming and information. To broaden

its audience, CHF has embraced the latest in communication

technology, including podcasting.

Podcasting refers to the regular Web-based distribution

of digital media files, which users download to portable

media players or personal computers to play back at a con-

venient time. The vast majority of podcasts are provided free

of charge, and the ability to podcast using inexpensive and

accessible technology makes it possible for organizations

like CHF to reach larger constituencies.

CHF’s weekly audio podcast, Distillations, seizes an

opportunity to enhance public appreciation of the chemical

and molecular sciences, technologies, and associated

industries in a new venue. The series, which debuted on

CHF Attracts New Audiences with

P o d c a s t

Distillations’ executive producer,Audra Wolfe, reviews a script.Photo by Victoria M. Indivero.

Page 6: Transmutations Newsletter

6

14 December 2007, brings historical perspective to contem-

porary issues in these fields. With examples from both the

distant and recent past, Distillations highlights how scientific

advances have improved our lives and how society can affect

the pace and direction of these advances. This exploration of

science’s historical roots is CHF’s distinct contribution to

the world of science podcasting, and it is attracting a lot

of attention.

As of 30 June Distillations had totals of about 34,000

visits, and nearly 24,000 downloads, well positioning the

podcast to reach the goal of 50,000 downloads in its first

year. It has a remarkably international subscriber base, with

repeat listeners from more than 20 countries. And a variety

of college and high-school classrooms, chemistry libraries,

online resource pages, and blogs have linked to Distillations’

Web site, where all of the 8– to 12–minute episodes can be

accessed.

Each episode of Distillations uses interviews, commen-

taries, reviews, and features to provide strong narratives

and expert opinions on a unifying theme.

For instance “Wonder Drugs,”

which aired on 22 February,

addresses how modern phar-

maceuticals, from antibiotics

to chemotherapy, have trans-

formed the experience of

illness in the 20th century.

Kiran Mazumdar-Shaw, founder

and chair of Biocon, discussed

how the global pharmaceutical

business is changing the culture

of science in India, while

David Caruso, manager of

the Biomedical Sciences and

Technologies Program of CHF’s

Center for Contemporary History

and Policy, commented on the

far-reaching effects of phar-

maceuticals in social, economic,

and political history.

Distillations

highlights

how scientific

advances have

improved our

lives and how

society can

affect the pace

and direction

of these

advances.

Page 7: Transmutations Newsletter

7

Market research and

Internet trend analysis indi-

cate that podcasting has

already become a powerful

communication tool, and its

importance will only increase

in the near future. As large

segments of the public, espe-

cially younger generations,

turn toward new media as

sources of information, it is

vital that CHF continue to

diversify the ways in which

it pursues its mission.

Distillations is an early, suc-

cessful step in that direction.

Distillations is a presentation of CHF and is made

possible by the generous support of the Richard

Lounsbery Foundation. To learn more about the

podcast, download an episode, or subscribe, please go

to http://distillations.chemheritage.org. Distillations

is also available on iTunes. Look for a new episode

every Friday.

CHF’s BlogsCHF followed up its podcasting venture by entering

the blogosphere.

� Periodic Tabloid is an ongoing record of Thomas

R. Tritton’s transition from college president to

president and CEO of CHF. Expect to be informed

and amused as Tritton shares his thoughts on this

new chapter of his career, on chemistry education,

and on scientific research.

� The Collective Voice offers a glimpse into the

world of CHF’s curatorial team as they open CHF’s

new museum, the completion of a project ten

years in the making. Discover the ins and outs of

exhibition planning through the staff’s tales of

achievements and challenges.

� The Center is CHF’s latest blog, where members of

the Center for Contemporary History and Policy

analyze current issues in biotechnology, electronics,

nanotechnology, and environmental science, evalu-

ating them through a historical lens.

To read and comment on these blogs, or for more

information, visit www.chemheritage.org.

The exploration

of science’s

historical roots

is CHF’s distinct

contribution

to science

podcasting.

Page 8: Transmutations Newsletter

8

Take Prozac, the molecule positioned at 1980 in Molecules

That Matter’s timeline. The first selective serotonin reuptake

inhibitor, Prozac emerged as a major new approach to treating

clinical depression in 1988, when it was approved by the U.S.

Food and Drug Administration. Within five years more than

eight million people had taken Prozac, and in 1999 Fortune

listed this revolutionary drug as one of its products of the

century. Artist Melissa Gwyn’s painting Prozac illustrates

use of the drug as so widespread that traces are found

in groundwater. The exhibition also includes examples of

Prozac’s cultural pervasiveness—a button declaring “Prozac

makes it better,” a pill case engraved with “Chance made us

sisters, Prozac made us friends”—as well as its controversial

standing in the chemical-imbalance hypothesis, which critics

claim is promoted by pharmaceutical companies merely to

sell such medications. The sheer scale of the

Prozac model reinforces the enormity of this

molecule’s impact.

Molecules That Matter opened at the Tang in

September 2007 and moved to CHF in July 2008.

It is the first installation to appear in the Clifford

C. Hach Gallery, the area in CHF’s new museum

devoted to rotating, science-themed exhibitions.

To fully seize the opportunity presented by hosting

this exhibition, CHF has organized a companion

lecture series for Molecules That Matter. Robert

S. Langer, Eric Roston, Chrissy Conant, Sandra

Steingraber, and Dawn A. Bonnell—all leaders

in their respective fields—are offering their

perspectives on the molecules, on the science in

everyday experiences, and on the promise and

peril of discovery and innovation.

Molecules That Matter

c o n t i n u e d f r o m p a g e 1

Top: Excerpts from the exhibition’s timeline. Above: A student tours Molecules That Matter

at the Tang. Photo by Art Evans.

Page 9: Transmutations Newsletter

9

These lectures are one more way that Molecules That

Matter encourages the general public to become informed

about and engaged with the socioscientific issues it

explores. For while our power over matter has vastly

improved the human experience, it has also affected the

biosphere in unanticipated ways, creating major challenges

for the world today. These challenges demand a better public

understanding of modern science, including the appreciation

of why molecules matter—the ultimate end to which this

exhibition aims.

Molecules That Matter remains in CHF’s Hach Gallery

through January 2009. Its tour then continues to The College

of Wooster in Wooster, Ohio; Baylor University in Waco,

Texas; and Grinnell College in Grinnell, Iowa. Funding for the

exhibition has been provided by The Camille and Henry

Dreyfus Foundation, the Hach Scientific Foundation, Amgen,

the Friends of the Tang, and donors to the Chemical Heritage

Foundation. To learn more about the Molecules That Matter

exhibition, the lecture series, or how to visit CHF’s new

museum, please go to www.chemheritage.org.

In conjunction with the Molecules That Matter

exhibition, CHF has invited five speakers, all leaders

in their fields, to offer perspectives on the molecules,

on the science in everyday experiences, and on the

promise and peril of discovery and innovation.

$15 per lecture. $45 for series. Students free with

valid ID. To register for the remaining lectures, or for

more information, visit www.chemheritage.org.

25 September

Biomaterials and How They Will Change Our Lives

Robert S. LangerInstitute Professor, Massachusetts Institute of Technology

7 October

The Beauty of Science and the Science of Beauty

Eric Rostonauthor of The Carbon Age: How Life's Core Element Has Become Civilization's Greatest Threat

21 October

An Artist Hijacks the Biochemistry of Life

Chrissy Conantartist featured in Molecules That Matter

11 November

The Many Faces of DDT

Sandra Steingraberauthor of Living Downstream: An Ecologist Looks at Cancer and the Environment

9 December

Linking Proteins, Wires, Dots, and Molecules into Useful Devices

Dawn A. BonnellTrustee Professor of Materials Science and director of the Nano/Bio Interface Center, University of Pennsylvania

Molecules THAT MATTERLecture Series

5:00 p.m. Exhibition opens

6:00 p.m. Lecture begins

7:00 p.m. Reception

Page 10: Transmutations Newsletter

farm. Still, Hach-Darrow’s mother, a former schoolteacher,

was anxious that her daughter go to college. And, with

precocious entrepreneurial skill, Hach-Darrow earned

seven hundred dollars from the sale of her turkeys in a

Thanksgiving market, which allowed her to attend what is

now Columbia College.

From there Hach-Darrow transferred to Iowa State

University, where she met Hach, who was studying analytical

chemistry and working in the laboratory of Harvey C. Diehl, Jr.

During World War II Hach received a deferment because many

of the lab’s projects—including the purification of thorium

and the generation of carbon dioxide—directly supported

the war effort.

During a date early in their relationship, Hach gave Hach-

Darrow a wrapped package containing Otto Eisenschiml’s

Without Fame: The Romance of a Profession. “Cliff said,

‘I want you to read this because we’re going to build a

chemical company,’” Hach-Darrow recalls. In 1943 the couple

married. Four years later Hach received his degree and bought

one acre of a flood plain in Ames, Iowa. On that land he and

Kathryn “Kitty” Hach-

Darrow and her first

husband, Clifford C.

Hach, after founding

their chemical company

in 1947, quickly became

legends in the water-analysis industry. Hach-Darrow ingen-

iously applied her love of aviation to the remarkable corporate

success she shared with Hach, flying to remote areas to

assist eager customers with the company’s groundbreaking

products. In fact Hach-Darrow’s passion for flying predates

even her business sense, which she first exhibited by raising

and selling turkeys to finance her college tuition.

Hach-Darrow grew up in rural Missouri during the Great

Depression. Before the economy buckled, her father was a

Ford Motor Company dealer who flew planes as a hobby, and

in 1928 he purchased an Eagle Rock biplane. “I fell in love

with airplanes at that moment and would cry to go in that

plane with my dad,” she reminisces. When the family fell on

hard times, they sold the plane and moved onto a wheat

10

Ready to FlyAbout Kathryn Hach-Darrow

Page 11: Transmutations Newsletter

11

Hach-Darrow built a three-room, cement-

block structure, which served as the lab,

office, and production facility of the business

they started, the Hach Chemical Company,

which eventually became the Hach Corporation.

The young firm’s first products were com-

pounds used for teaching organic chemistry.

The move away from selling student samples

began in 1949, when Hach produced a new

method for water testing. The home water-

softener business was emerging, but water-

softener salesmen needed a better test to

make their pitch to housewives. Soon Hach

was supplying the Model 5B Hardness Test

Kit to Culligan Water Conditioning, Sears-

Roebuck and Company, and others.

Hach then recognized an industry that did not yet fully

exist: municipal water testing. In the early 1950s the typical

municipal water authority was understaffed, it had to make

its own reagents, and it used complex procedures to test

water quality. Hach developed simplified procedures and

combined several reagents, for everything from acid to zinc,

into single-dosage powder packages, marketed as “powder

pillows.” The new product met with instant success, and the

company grew rapidly in sales and reputation. By the year

2000 the production of powder pillows had reached 200

million units per year.

In addition to filling a demonstrated need

with their revolutionary product, the Hach

Corporation set standards in customer service.

It was an early provider of phone-based tech-

nical service, and it established a hands-on

training center. But it was most famous for its

flying. Hach-Darrow essentially brought the

company to underserved customers by piloting

her planes to small rural towns, where she

provided technical training and on-site prob-

lem solving. She was known throughout the

water-analysis industry as the woman whose

sales force was ready to fly anywhere to fix

things fast.

In 1957, just ten years after they founded

the company, the Hachs jointly won the

American Water Works George Fuller Award

for distinguished service in the water-supply

field. The Hach Corporation became publicly

traded in 1968 and by 1998 had sales of $150

million per year. Hach-Darrow oversaw the

business operations, marketing, and other

managerial aspects of the firm until its sale in

1999. In 2003, in recognition of her entrepre-

neurship, scientific contributions, and exceptional service,

Hach-Darrow was awarded the Pittcon Heritage Award and

entered the Pittcon Hall of Fame.

Today Hach-Darrow serves as chairman of the board of

the Hach Scientific Foundation, which provides scholarships

to chemistry students and teachers. She and her son, Bruce

Hach, who also serves on the Hach Scientific Foundation’s

board of directors, have collaborated with CHF on several

projects, including an oral history and the traveling exhibition

Her Lab in Your Life: Women in Chemistry. They also made

the lead gift in support of the creation of CHF’s new museum,

in which the gallery for rotating exhibitions was dedicated in

Clifford C. Hach’s memory. For more information about the

Clifford C. Hach Gallery, please visit www.chemheritage.org.

Hach-Darrow

was known

as the woman

ready to fly

anywhere to

fix things fast.

Left page, bottom to top: Kathryn Hach-Darrow pilots a BeechcraftBonanza. Hach-Darrow, wearing helmet and goggles, with family members and her father’s Eagle Rock biplane. Above: Hach-Darrowbeside one of her beloved planes. Photos courtesy Hach Scientific Foundation.

Page 12: Transmutations Newsletter

Masao Horiba proved the exception to the Japanese adage

that the nail that stands out gets beaten down. Horiba forged

his own path to corporate success, becoming a pioneer in the

analytical instrument industry and building a giant global

organization out of little more than a storefront operation.

Today Horiba dares others to be distinct. “Let the nail stand

out” is a cornerstone of his management philosophy, and his

own story is proof of the achievement that may follow.

In his youth Horiba dreamed of becoming a nuclear

physicist. But when, in 1945, American authorities banned

the study of nuclear physics in Japan, he had to find a new

goal. Horiba decided to abandon his studies at Kyoto

University and instead face the challenges of the free market.

He founded his own firm, Horiba Radio Laboratory (HRL),

which specialized in the production of electronic parts, the

repair of measurement instruments, and the restoration of

discarded batteries. Batteries were a particularly profitable

business, as postwar Japan’s power-distribution system was

not very consistent. HRL also made such medical devices as

electric-pulse oscillators, which were used in hospitals.

In 1952 Horiba developed a new product that would

change the course of the company. Japan’s economy was

booming, and the Japanese chemical and food industries

needed low-cost, dependable pH meters, but imported

versions were expensive and unreliable in Japan’s humid

climate. Soon Horiba pH meters were launched onto a ready

market with instant success, reaching sales in excess of

one million yen per month in the first year. The meters quickly

gained a reputation for excellence, and “pH equals Horiba”

became an accepted maxim in the Japanese chemical world.

In 1953 HRL became Horiba Ltd., with Horiba as president.

Aware that continued commercial success depends on

seizing new opportunities, Horiba next sought to broaden the

range of analytical instruments his company produced.

Japan’s chemical industry

was shifting its focus from

liquid-phase to gas-phase

reactions, and Horiba

foresaw a market for

reliable, inexpensive, and

12

The NailThat Stood OutAbout Masao Horiba

Above: Masao Horiba as a young student. Right: Horiba’s first pH meter, the Model H.

Photos courtesy Horiba, Ltd.

Page 13: Transmutations Newsletter

efficient gas analyzers. In 1958 Horiba staked the company’s

future on the development of infrared (IR) analyzers. Sales of

IR units were slow at first but took off in 1962.

Horiba Ltd.’s IR expertise became the basis of its next

great success, which occurred in the context of growing

international concern about the environment in the early

1960s. Government researchers approached the company

about using a version of the Horiba exhalation-measuring

system, a device designed for medical use, to gauge

auto emissions. “I couldn’t believe what they were

saying,” Horiba recalls. “This machine is used in

operating rooms, where the air is

clean and dust free. How can you

measure gas with dust and oil in it?

I declined their order.”

But Masahiro Oura, a young sci-

entist at Horiba Ltd., saw this as an

opportunity to seize and began secretly

working on the project. Horiba was

furious when he discovered what Oura

was doing, until it became clear that

Oura already had firm orders from auto manufacturers

Toyota, Nissan, and Mazda. Horiba had to abide by

his own motto about letting the nail stand out, and

the outcome was the MEXA-1, produced in 1964.

This auto-emissions measurement device was the

first in a series, each incorporating newer technology

to achieve higher levels of sensitivity. The devices

became the springboard for Horiba Ltd.’s expansion into

foreign markets: by the mid-1970s MEXA systems were

being delivered to the U.S. Environmental Protection Agency

and Mercedes-Benz, and additional orders poured in. Today

sales of such systems account for over 27% of the company’s

total turnover.

Confident about the course of the company, Horiba

retired as president of Horiba Ltd. in 1978. At the age of 53

he became company chairman, while the presidency was

passed to Oura. In 1992 Oura was succeeded by Horiba’s son,

Atsushi Horiba. Horiba later relinquished his executive

rights and now serves as Horiba Ltd.’s

supreme counsel.

In recent years Horiba has devoted him-

self to activities outside the company. He has

encouraged venture investment in Kyoto and

spoken about the importance of venture capital

initiatives at economic conferences. He has

also become a popular author and lecturer

on management issues, espousing his funda-

mental ideas that work must be enjoyable and

fulfilling and that business leaders should take chances and

let the nail stand out.

In recognition of his entrepreneurship, his contributions

to the instrumentation industry, and his service to society,

Horiba was awarded the Pittcon Heritage Award and entered

the Pittcon Hall of Fame in 2006. “Out of all of the awards

I have received so far, this makes me the happiest,”

he declared.

Horiba’s relationship with CHF dates from an oral history

conducted after an initial meeting at Pittcon 2003. A sub-

stantial gift from Horiba Ltd. helped make possible CHF’s

new museum, in which the Masao Horiba Exhibit Hall was

dedicated in his honor. For more information about the exhibit

hall, please visit www.chemheritage.org.

13

Above: Horiba in 2005. Left: Horiba, in center at window,embarking on his first business trip to the United States.Photos courtesy Horiba, Ltd.

Horiba forged

his own path

to success in

the analytical

instrument

industry.

Page 14: Transmutations Newsletter

14

Treasure the past Educate the present Inspire the future

25th Anniversary InitiativeProgresseventsA Note from the ChancellorSuccess has a thousand fathers, and CHF surely has cause to celebrate all

the thousands of you who have given of your time and talents to ensure the

success of our 25th Anniversary Initiative. Thank you!

CHF’s comprehensive campaign has enabled us to do three things critical

to CHF’s growing work in the world:

• To complete the fit-out and modernization of our 100,000-square-foot head-

quarters, and thereby to provide both a jewel box worthy of the treasures of

CHF’s heritage and a state-of-the-art exhibition space, conference center,

and think tank fitted to our global mission.

• To develop the staff, the educational programs, the Web and printed

publications, and the conferences and events that give life to the heritage of

the chemical and molecular sciences.

• To build the endowment that brings permanence and security to our opera-

tions and underpins our ability to accept precious heirlooms (whether 16th-

century books or the archives of a recent Nobel laureate) for time and eternity.

After 25-plus years, a nd with this landmark campaign successfully

completed, CHF is poised to take its place on the world stage as the Chemical

Heritage Foundation.

The forward march of the chemical sciences steadily accelerates its pace

(think Moore’s Law!); the challenges of education and of public understanding

increase; the need for sane perspectives on contemporary history and policy

has never been greater. Hence, like you, I look forward to CHF’s growing

ability to treasure the past, educate the present, and inspire the future.

The best is yet to be. Thank you again.

Arnold Thackray

CHF thanks

all of you

who ensured

the success

of our 25th

Anniversary

Initiative.

Page 15: Transmutations Newsletter

1515

Clockwise, from below: Leroy Hood, center, accepts the 2008 Pittcon HeritageAward from Jane Chan, Pittcon program chair, and John Varine, Pittcon presi-dent. Photo by Peter Cutts. Participants discuss the dilemmas of dual use at the2008 Gordon Cain Conference. Ronald Breslow listens to a speaker in CHF’sUllyot Meeting Hall. Haldor Topsøe, this year’s winner of The Chemists’ Club’sWinthrop-Sears Medal, on Heritage Day 2008. Nobel laureate Walter Gilbert,co-recipient of the 2008 American Institute of Chemists’ Gold Medal, left,talks with Henrik and Nan Topsøe in CHF’s rare book room. Photos by Douglas A.Lockard. Peter Huntsman, second from left, accepts the 2008 PetrochemicalHeritage Award surrounded by, from left, Gerald Law, Tom Tritton, John Shelton,Douglas Culpon, and Ron Woliver. Photo courtesy Sam’s Studio.

Page 16: Transmutations Newsletter

Chemical Heritage Foundation315 Chestnut StreetPhiladelphia, PA 19106

Treasure t h e p a s tEducate t h e p r e s e n t

Inspire t h e f u t u r e

Transmutations INTHISISSUE

145

14

Molecules That Matter

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CHF’s Podcast: Distillations

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